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ONTOLOGY REPORT - ANNOTATIONS


Term:ketone body catabolic process
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Accession:GO:0046952 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.
Synonyms:exact_synonym: ketolysis;   ketone body breakdown;   ketone body catabolism;   ketone body degradation;   utilization of ketone bodies
 xref: MetaCyc:PWY66-368;   Reactome:R-HSA-77108


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ketone body catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acat1 acetyl-CoA acetyltransferase 1 JBrowse link 8 58,166,990 58,195,884 RGD:1624291
G Acat2 acetyl-CoA acetyltransferase 2 JBrowse link 1 47,972,399 47,992,654 RGD:2326095
G Oxct1 3-oxoacid CoA transferase 1 JBrowse link 2 53,859,738 54,007,733 RGD:1624291
G Oxct2b 3-oxoacid CoA transferase 2B JBrowse link 5 140,813,957 140,815,711 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    metabolic process 11899
      small molecule metabolic process 1824
        small molecule catabolic process 354
          ketone body catabolic process 4
            acetoacetic acid catabolic process 0
            acetone catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 19576
    metabolic process 11899
      cellular metabolic process 10737
        drug metabolic process 591
          drug catabolic process 157
            ketone body catabolic process 4
              acetoacetic acid catabolic process 0
              acetone catabolic process 0
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