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ONTOLOGY REPORT - ANNOTATIONS

Term:ketone body catabolic process
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Accession:GO:0046952 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.
Synonyms:exact_synonym: ketolysis;   ketone body breakdown;   ketone body catabolism;   ketone body degradation;   utilization of ketone bodies
 xref: MetaCyc:PWY66-368;   Reactome:R-HSA-77108 "Utilization of Ketone Bodies"


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ketone body catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO
IEA 		(PMID:1979337)
GO_REF:0000107 		RGD
Ensembl		 PMID:1979337 GO_REF:0000107 NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 IEP RGD PMID:5116556 RGD:2326095 NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Oxct1 3-oxoacid CoA transferase 1 involved_in
acts_upstream_of_or_within 		IEA
ISO 		GO_REF:0000002
MGI:4364940 (PMID:21209089)
GO_REF:0000107 		InterPro
RGD
Ensembl		 PMID:21209089 GO_REF:0000002 GO_REF:0000107 NCBI chr 2:54,963,964...55,112,303
Ensembl chr 2:53,236,368...53,384,714 		JBrowse link
G Oxct2a 3-oxoacid CoA transferase 2A involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:140,885,914...140,887,672
Ensembl chr 5:135,591,507...135,602,569 		JBrowse link
G Oxct2b 3-oxoacid CoA transferase 2B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:140,681,746...140,683,500 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        catabolic process 2962
          small molecule catabolic process 372
            ketone body catabolic process 5
              acetoacetic acid catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        primary metabolic process 10727
          lipid metabolic process 1485
            fatty acid derivative metabolic process 69
              fatty acid derivative catabolic process 23
                ketone body catabolic process 5
                  acetoacetic acid catabolic process 0
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