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ONTOLOGY REPORT - ANNOTATIONS


Term:ketone body biosynthetic process
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Accession:GO:0046951 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA.
Synonyms:exact_synonym: ketone body anabolism;   ketone body biosynthesis;   ketone body formation;   ketone body synthesis


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ketone body biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase involved_in ISO (PMID:22847177), (PMID:22865860), (PMID:9200711) RGD
UniProt
PMID:2573547 PMID:9200711 PMID:22847177 PMID:22865860 RGD:1599519 NCBI chrNW_004955452:3,720,103...3,734,730
Ensembl chrNW_004955452:3,720,103...3,735,192
JBrowse link
G Hmgcll1 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1 involved_in ISO (PMID:22847177), (PMID:22865860) UniProt PMID:22847177 PMID:22865860 NCBI chrNW_004955411:760,660...881,415
Ensembl chrNW_004955411:795,145...880,033
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 involved_in ISO (PMID:23751782) RGD
UniProt
PMID:12399220 PMID:23751782 RGD:2326121 NCBI chrNW_004955435:22,804,484...22,820,807
Ensembl chrNW_004955435:22,804,484...22,821,482
JBrowse link
G Slc27a5 solute carrier family 27 member 5 acts_upstream_of_or_within ISO (MGI:3722951|PMID:16618416) MGI PMID:16618416 MGI:3722951 NCBI chrNW_004955584:1,112,387...1,121,500
Ensembl chrNW_004955584:1,112,117...1,121,323
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11982
    metabolic process 7566
      biosynthetic process 3903
        cellular biosynthetic process 3783
          ketone body biosynthetic process 4
            acetoacetic acid biosynthetic process 0
            acetone biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 11982
    cellular process 11219
      cellular metabolic process 6951
        generation of precursor metabolites and energy 327
          ketone body metabolic process 9
            ketone body biosynthetic process 4
              acetoacetic acid biosynthetic process 0
              acetone biosynthetic process 0
paths to the root