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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular ketone body metabolic process
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Accession:GO:0046950 term browser browse the term
Definition:The chemical reactions and pathways involving ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone, as carried out by individual cells. Although 3-hydroxybutyrate is not a ketone, it is classed as a ketone body because it exists in an equilibrium with acetoacetate. Ketone bodies may accumulate in excessive amounts in the body in starvation, diabetes mellitus or in other defects of carbohydrate metabolism.
Synonyms:exact_synonym: cellular ketone body metabolism


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cellular ketone body metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Oxct1 3-oxoacid CoA-transferase 1 JBrowse link NW_004936518 924,840 1,057,201 RGD:9068941
ketone body biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aacs acetoacetyl-CoA synthetase JBrowse link NW_004936558 327,822 373,474 RGD:9068941
G Acat1 acetyl-CoA acetyltransferase 1 JBrowse link NW_004936551 594,647 626,016 RGD:9068941
G Acss3 acyl-CoA synthetase short chain family member 3 JBrowse link NW_004936698 1,929,683 2,089,703 RGD:9068941
G Bdh1 3-hydroxybutyrate dehydrogenase 1 JBrowse link NW_004936833 367,790 409,966 RGD:9068941
G Bdh2 3-hydroxybutyrate dehydrogenase 2 JBrowse link NW_004936520 278,467 304,525 RGD:9068941
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase JBrowse link NW_004936474 8,955,216 8,971,078 RGD:9068941
G Hmgcll1 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1 JBrowse link NW_004936476 5,600,154 5,735,721 RGD:9068941
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 JBrowse link NW_004936627 4,451,847 4,473,163 RGD:9068941
G Slc27a5 solute carrier family 27 member 5 JBrowse link NW_004937062 90,217 98,562 RGD:9068941
ketone body catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acat1 acetyl-CoA acetyltransferase 1 JBrowse link NW_004936551 594,647 626,016 RGD:9068941
G Bdh1 3-hydroxybutyrate dehydrogenase 1 JBrowse link NW_004936833 367,790 409,966 RGD:9068941
G Oxct1 3-oxoacid CoA-transferase 1 JBrowse link NW_004936518 924,840 1,057,201 RGD:9068941

Term paths to the root
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  biological_process 14835
    metabolic process 10258
      cellular metabolic process 9544
        cellular ketone body metabolic process 10
          ketone body biosynthetic process + 9
          ketone body catabolic process + 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.