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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular ketone body metabolic process
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Accession:GO:0046950 term browser browse the term
Definition:The chemical reactions and pathways involving ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone, as carried out by individual cells. Although 3-hydroxybutyrate is not a ketone, it is classed as a ketone body because it exists in an equilibrium with acetoacetate. Ketone bodies may accumulate in excessive amounts in the body in starvation, diabetes mellitus or in other defects of carbohydrate metabolism.
Synonyms:exact_synonym: cellular ketone body metabolism


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cellular ketone body metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Oxct1 3-oxoacid CoA transferase 1 JBrowse link 15 4,026,428 4,155,344 RGD:2290270
G Oxct2a 3-oxoacid CoA transferase 2A JBrowse link 4 123,321,875 123,323,679 RGD:2290270
ketone body biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hmgcl 3-hydroxy-3-methylglutaryl-Coenzyme A lyase JBrowse link 4 135,946,448 135,962,668 RGD:2290270
G Hmgcll1 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1 JBrowse link 9 76,014,698 76,136,350 RGD:2290270
G Hmgcs2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 JBrowse link 3 98,280,431 98,310,738 RGD:2290270
G Slc27a5 solute carrier family 27 (fatty acid transporter), member 5 JBrowse link 7 12,988,346 12,998,192 RGD:2290270
ketone body catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acat1 acetyl-Coenzyme A acetyltransferase 1 JBrowse link 9 53,580,522 53,610,350 RGD:2290270
G Oxct1 3-oxoacid CoA transferase 1 JBrowse link 15 4,026,428 4,155,344 RGD:2290270
G Oxct2a 3-oxoacid CoA transferase 2A JBrowse link 4 123,321,875 123,323,679 RGD:2290270
G Oxct2b 3-oxoacid CoA transferase 2B JBrowse link 4 123,116,248 123,118,000 RGD:2290270

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  biological_process 23162
    metabolic process 10900
      cellular metabolic process 9695
        cellular ketone body metabolic process 8
          ketone body biosynthetic process + 4
          ketone body catabolic process + 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.