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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of neurotransmitter secretion
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Accession:GO:0046929 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.
Synonyms:exact_synonym: down regulation of neurotransmitter secretion;   downregulation of neurotransmitter secretion
 narrow_synonym: conotoxin activity;   inhibition of neurotransmitter secretion


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negative regulation of neurotransmitter secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asic1 acid sensing ion channel subunit 1 acts_upstream_of_or_within ISO MGI:2179834 (MGI:3841883|PMID:18094106) RGD PMID:18094106 MGI:3841883 NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541
JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857478|MGI:97321 (MGI:3612345|PMID:16298082)
Ensembl
RGD
PMID:16298082 GO_REF:0000107 MGI:3612345 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing involved_in
acts_upstream_of_or_within
ISO (PMID:25730884)
MGI:2152971|MGI:2152972 (MGI:5634213|PMID:25730884)
RGD PMID:25730884 MGI:5634213 NCBI chr 9:75,868,620...75,937,126
Ensembl chr 9:75,867,468...75,937,124
JBrowse link
G Slc30a1 solute carrier family 30 member 1 involved_in IMP PMID:16741752 BHF-UCL PMID:16741752 RGD:8554228 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
JBrowse link
G Syt4 synaptotagmin 4 involved_in IDA PMID:10397765 ParkinsonsUK-UCL PMID:10397765 RGD:11535116 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332
JBrowse link
negative regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr6 5-hydroxytryptamine receptor 6 IMP RGD PMID:16987217 RGD:2317005 NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912
JBrowse link
negative regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A IMP RGD PMID:16899074 RGD:10002752 NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:22314364) RGD PMID:22314364 NCBI chr 1:48,688,651...49,882,520 JBrowse link
negative regulation of synaptic vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (MGI:5490391|PMID:23616533) RGD PMID:23616533 MGI:5490391 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Fmr1 FMRP translational regulator 1 involved_in IMP PMID:24709664 UniProt PMID:24709664 RGD:11059581 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:894315 (MGI:5490391|PMID:23616533)
RGD PMID:23616533 PMID:21873635 MGI:5490391, RGD:13792537 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:97852 (MGI:5490391|PMID:23616533)
RGD PMID:23616533 PMID:21873635 MGI:5490391, RGD:13792537 NCBI chr 7:53,423,039...53,456,388
Ensembl chr 7:53,423,130...53,456,370
JBrowse link
G Syt4 synaptotagmin 4 involved_in ISO (MGI:4457852|PMID:19448629) RGD PMID:19448629 MGI:4457852 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    signaling 7460
      negative regulation of signaling 1405
        negative regulation of synaptic transmission 85
          negative regulation of neurotransmitter secretion 12
            negative regulation by symbiont of host neurotransmitter secretion 0
            negative regulation of acetylcholine secretion, neurotransmission 1
            negative regulation of glutamate secretion, neurotransmission 0
            negative regulation of glycine secretion, neurotransmission 0
            negative regulation of spontaneous neurotransmitter secretion 2
            negative regulation of substance P secretion, neurotransmission 0
            negative regulation of synaptic vesicle exocytosis + 5
Path 2
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      cell communication 7543
        cell-cell signaling 1735
          synaptic signaling 919
            trans-synaptic signaling 892
              anterograde trans-synaptic signaling 883
                chemical synaptic transmission 883
                  modulation of chemical synaptic transmission 651
                    regulation of neurotransmitter secretion 137
                      negative regulation of neurotransmitter secretion 12
                        negative regulation by symbiont of host neurotransmitter secretion 0
                        negative regulation of acetylcholine secretion, neurotransmission 1
                        negative regulation of glutamate secretion, neurotransmission 0
                        negative regulation of glycine secretion, neurotransmission 0
                        negative regulation of spontaneous neurotransmitter secretion 2
                        negative regulation of substance P secretion, neurotransmission 0
                        negative regulation of synaptic vesicle exocytosis + 5
paths to the root