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Term:tetrahydrofolylpolyglutamate biosynthetic process
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Accession:GO:0046901 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues.
Synonyms:exact_synonym: THF polyglutamylation;   tetrahydrofolate polyglutamylation;   tetrahydrofolyl-[Glu](n) biosynthesis;   tetrahydrofolyl-[Glu](n) biosynthetic process;   tetrahydrofolylpolyglutamate anabolism;   tetrahydrofolylpolyglutamate biosynthesis;   tetrahydrofolylpolyglutamate formation;   tetrahydrofolylpolyglutamate synthesis
 broad_synonym: folic-acid containing compound polyglutamylation

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tetrahydrofolylpolyglutamate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fpgs folylpolyglutamate synthase ISO
(PMID:25164808), (PMID:3619447)
PMID:3619447 PMID:25164808, PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 3:11,717,667...11,729,694
Ensembl chr 3:11,717,667...11,723,327
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  biological_process 20045
    cellular process 18859
      cellular metabolic process 11041
        cellular modified amino acid metabolic process 204
          folic acid-containing compound metabolic process 28
            tetrahydrofolylpolyglutamate metabolic process 2
              tetrahydrofolylpolyglutamate biosynthetic process 1
Path 2
Term Annotations click to browse term
  biological_process 20045
    metabolic process 12102
      cellular metabolic process 11041
        heterocycle metabolic process 5631
          pteridine-containing compound metabolic process 34
            pteridine-containing compound biosynthetic process 15
              folic acid-containing compound biosynthetic process 9
                tetrahydrofolylpolyglutamate biosynthetic process 1
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