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ONTOLOGY REPORT - ANNOTATIONS

Term:quinolinate metabolic process
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Accession:GO:0046874 term browser browse the term
Definition:The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
Synonyms:exact_synonym: quinolinate metabolism


show annotations for term's descendants           Sort by:
quinolinate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IDA
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:2940338 PMID:3112306 PMID:9870556 GO_REF:0000033, RGD:2290301, RGD:2290302, RGD:2290370 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
G Qprt quinolinate phosphoribosyltransferase IDA RGD PMID:8694849 RGD:2289495 NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486 		JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:12140278)
GO_REF:0000104
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:12140278 GO_REF:0000024 GO_REF:0000104 GO_REF:0000107 NCBI chr13:39,200,412...39,245,954
Ensembl chr13:39,200,314...39,245,209 		JBrowse link
quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl10 BCL10, immune signaling adaptor acts_upstream_of_or_within ISO (PMID:2419335) RGD PMID:2419335 NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Bin1 bridging integrator 1 acts_upstream_of_or_within ISO (PMID:2419335) RGD PMID:2419335 NCBI chr18:24,282,840...24,341,461
Ensembl chr18:24,009,653...24,067,263 		JBrowse link
G E2f1 E2F transcription factor 1 acts_upstream_of_or_within ISO (PMID:2419335) RGD PMID:2419335 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G Extl3 exostosin-like glycosyltransferase 3 acts_upstream_of_or_within ISO (PMID:2419335) RGD PMID:2419335 NCBI chr15:39,294,033...39,384,086
Ensembl chr15:39,293,605...39,338,898 		JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in ISO
IEA 		(PMID:28792876)
GO_REF:0000104 		RGD
UniProt		 PMID:28792876 GO_REF:0000104 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
G Htt huntingtin acts_upstream_of_or_within ISO MGI:1861934|MGI:1861935 (PMID:16697652) RGD PMID:16697652 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in ISO
IEA 		(PMID:2419335)
GO_REF:0000107 		RGD
Ensembl		 PMID:2419335 GO_REF:0000107 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104
GO_REF:0000002 		UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr13:90,089,340...90,121,108
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G Kynu kynureninase involved_in ISO
IEA 		(PMID:9291104)
GO_REF:0000104 		RGD
UniProt		 PMID:9291104 GO_REF:0000104 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Rac1 Rac family small GTPase 1 acts_upstream_of_or_within ISO (PMID:2419335) RGD PMID:2419335 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Reg3g regenerating family member 3 gamma acts_upstream_of_or_within ISO (PMID:2419335) RGD PMID:2419335 NCBI chr 4:112,482,183...112,484,738
Ensembl chr 4:110,924,168...110,926,723 		JBrowse link
G Xiap X-linked inhibitor of apoptosis acts_upstream_of_or_within ISO (PMID:2419335) RGD PMID:2419335 NCBI chr  X:125,756,107...125,803,979
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
quinolinate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Qprt quinolinate phosphoribosyltransferase involved_in
acts_upstream_of_or_within 		ISO
IBA 		(PMID:24038671), (PMID:3409840), (PMID:9473669)
GO_REF:0000033
(PMID:9473669) 		RGD
GO_Central		 PMID:3409840 PMID:9473669 PMID:24038671 GO_REF:0000033 NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        pyridine-containing compound metabolic process 251
          quinolinate metabolic process 14
            quinolinate biosynthetic process + 13
            quinolinate catabolic process 1
Path 2
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      metabolic process 12158
        small molecule metabolic process 1944
          organic acid metabolic process 1062
            oxoacid metabolic process 1040
              carboxylic acid metabolic process 1025
                dicarboxylic acid metabolic process 113
                  quinolinate metabolic process 14
                    quinolinate biosynthetic process + 13
                    quinolinate catabolic process 1
paths to the root