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ONTOLOGY REPORT - ANNOTATIONS

Term:quinolinate metabolic process
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Accession:GO:0046874 term browser browse the term
Definition:The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
Synonyms:exact_synonym: quinolinate metabolism

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quinolinate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase involved_in ISO
IEA 		RGD
TreeGrafter		 PMID:2940338 PMID:3112306 PMID:9870556 GO_REF:0000118 RGD:2290301 RGD:2290302 RGD:2290370 NCBI chr14:64,460,553...64,485,731
Ensembl chr14:64,460,703...64,485,378 		JBrowse link
G QPRT quinolinate phosphoribosyltransferase ISO RGD PMID:8694849 RGD:2289495 NCBI chr 5:26,953,980...26,970,120
Ensembl chr 5:26,950,391...26,970,079 		JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACMSD aminocarboxymuconate semialdehyde decarboxylase involved_in IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chr10:19,063,731...19,128,387
Ensembl chr10:19,064,115...19,129,089 		JBrowse link
quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL10 BCL10 immune signaling adaptor acts_upstream_of_or_within ISO (PMID:2419335) UniProt PMID:2419335 NCBI chr20:48,073,489...48,084,635
Ensembl chr20:48,073,800...48,085,136 		JBrowse link
G BIN1 bridging integrator 1 acts_upstream_of_or_within ISO (PMID:2419335) UniProt PMID:2419335 NCBI chr10:3,112,605...3,173,522
Ensembl chr10:3,113,868...3,173,620 		JBrowse link
G E2F1 E2F transcription factor 1 acts_upstream_of_or_within ISO (PMID:2419335) UniProt PMID:2419335 NCBI chr 2:37,968,541...37,980,461
Ensembl chr 2:37,968,556...37,980,326 		JBrowse link
G EXTL3 exostosin like glycosyltransferase 3 acts_upstream_of_or_within ISO (PMID:2419335) UniProt PMID:2419335 NCBI chr 8:26,729,772...26,861,953
Ensembl chr 8:26,821,141...26,864,926 		JBrowse link
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chr14:64,460,553...64,485,731
Ensembl chr14:64,460,703...64,485,378 		JBrowse link
G HTT huntingtin acts_upstream_of_or_within ISO (PMID:16697652) MGI PMID:16697652 NCBI chr27:45,493,467...45,657,690
Ensembl chr27:45,497,352...45,657,621 		JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:37,930,910...37,950,790
Ensembl chr 8:37,930,562...37,946,505 		JBrowse link
G KMO kynurenine 3-monooxygenase involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr25:78,611,194...78,670,314
Ensembl chr25:78,628,757...78,670,181 		JBrowse link
G KYNU kynureninase involved_in IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr10:28,230,129...28,394,103
Ensembl chr10:28,230,508...28,394,076 		JBrowse link
G RAC1 Rac family small GTPase 1 acts_upstream_of_or_within ISO (PMID:2419335) UniProt PMID:2419335 NCBI chr28:15,583,609...15,610,753
Ensembl chr28:15,583,516...15,610,328 		JBrowse link
G REG3G regenerating family member 3 gamma acts_upstream_of_or_within ISO (PMID:2419335) UniProt PMID:2419335 NCBI chr14:28,213,731...28,217,299 JBrowse link
G XIAP X-linked inhibitor of apoptosis acts_upstream_of_or_within ISO (PMID:2419335) UniProt PMID:2419335
quinolinate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G QPRT quinolinate phosphoribosyltransferase involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:26,953,980...26,970,120
Ensembl chr 5:26,950,391...26,970,079 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19826
    cellular process 19340
      metabolic process 13108
        pyridine-containing compound metabolic process 202
          quinolinate metabolic process 14
            quinolinate biosynthetic process + 13
            quinolinate catabolic process 1
Path 2
Term Annotations click to browse term
  biological_process 19826
    cellular process 19340
      metabolic process 13108
        small molecule metabolic process 1741
          organic acid metabolic process 928
            oxoacid metabolic process 919
              carboxylic acid metabolic process 901
                dicarboxylic acid metabolic process 111
                  quinolinate metabolic process 14
                    quinolinate biosynthetic process + 13
                    quinolinate catabolic process 1
paths to the root