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ONTOLOGY REPORT - ANNOTATIONS

Term:quinolinate metabolic process
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Accession:GO:0046874 term browser browse the term
Definition:The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
Synonyms:exact_synonym: quinolinate metabolism


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quinolinate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase involved_in ISO
IBA 		RGD
GO_Central		 PMID:2940338 PMID:3112306 PMID:9870556 GO_REF:0000033 RGD:2290301 RGD:2290302 RGD:2290370 NCBI chr10:45,368,157...45,379,521
Ensembl chr10:45,368,178...45,379,160 		JBrowse link
G QPRT quinolinate phosphoribosyltransferase ISO RGD PMID:8694849 RGD:2289495 NCBI chr 6:17,778,664...17,794,110
Ensembl chr 6:17,779,439...17,794,035 		JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACMSD aminocarboxymuconate semialdehyde decarboxylase involved_in IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr19:37,658,999...37,725,426
Ensembl chr19:37,659,226...37,725,172 		JBrowse link
quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL10 BCL10 immune signaling adaptor acts_upstream_of_or_within ISO (PMID:2419335) UniProt PMID:2419335 NCBI chr 6:62,712,937...62,723,852
Ensembl chr 6:62,712,971...62,722,368 		JBrowse link
G BIN1 bridging integrator 1 acts_upstream_of_or_within ISO (PMID:2419335) UniProt PMID:2419335 NCBI chr19:23,503,934...23,534,407
Ensembl chr19:23,375,363...23,534,303 		JBrowse link
G E2F1 E2F transcription factor 1 acts_upstream_of_or_within ISO (PMID:2419335) UniProt PMID:2419335 NCBI chr24:22,895,149...22,904,689
Ensembl chr24:22,878,402...22,904,656 		JBrowse link
G EXTL3 exostosin like glycosyltransferase 3 acts_upstream_of_or_within ISO (PMID:2419335) UniProt PMID:2419335 NCBI chr25:28,788,803...28,833,964
Ensembl chr25:28,790,506...28,937,647 		JBrowse link
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA UniProt GO_REF:0000104 NCBI chr10:45,368,157...45,379,521
Ensembl chr10:45,368,178...45,379,160 		JBrowse link
G HTT huntingtin acts_upstream_of_or_within ISO (PMID:16697652) MGI PMID:16697652 NCBI chr 3:61,076,934...61,221,462
Ensembl chr 3:61,079,904...61,330,290 		JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 involved_in ISO (PMID:2419335) UniProt PMID:2419335 NCBI chr16:25,391,759...25,407,161
Ensembl chr16:25,391,754...25,407,048 		JBrowse link
G KMO kynurenine 3-monooxygenase involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr 7:32,941,487...32,994,541
Ensembl chr 7:32,941,487...32,994,541 		JBrowse link
G KYNU kynureninase involved_in IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr19:45,022,450...45,150,977
Ensembl chr19:45,022,072...45,149,339 		JBrowse link
G RAC1 Rac family small GTPase 1 acts_upstream_of_or_within ISO (PMID:2419335) UniProt PMID:2419335 NCBI chr 6:11,726,259...11,758,532
Ensembl chr 6:11,655,494...11,757,216 		JBrowse link
G REG3A regenerating islet-derived 3 alpha acts_upstream_of_or_within ISO (PMID:2419335) UniProt PMID:2419335 NCBI chr17:44,859,106...44,864,793
Ensembl chr17:44,859,137...44,861,899 		JBrowse link
G XIAP X-linked inhibitor of apoptosis acts_upstream_of_or_within ISO (PMID:2419335) UniProt PMID:2419335 NCBI chr  X:95,300,234...95,356,103
Ensembl chr  X:95,331,827...95,351,582 		JBrowse link
quinolinate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G QPRT quinolinate phosphoribosyltransferase acts_upstream_of_or_within
involved_in 		ISO
IBA 		(PMID:9473669) MGI
GO_Central		 PMID:9473669 GO_REF:0000033 NCBI chr 6:17,778,664...17,794,110
Ensembl chr 6:17,779,439...17,794,035 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22130
    cellular process 21660
      metabolic process 15378
        pyridine-containing compound metabolic process 225
          quinolinate metabolic process 14
            quinolinate biosynthetic process + 13
            quinolinate catabolic process 1
Path 2
Term Annotations click to browse term
  biological_process 22130
    cellular process 21660
      metabolic process 15378
        small molecule metabolic process 1830
          organic acid metabolic process 983
            oxoacid metabolic process 970
              carboxylic acid metabolic process 955
                dicarboxylic acid metabolic process 113
                  quinolinate metabolic process 14
                    quinolinate biosynthetic process + 13
                    quinolinate catabolic process 1
paths to the root