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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of bone remodeling
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Accession:GO:0046851 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling.
Synonyms:exact_synonym: down regulation of bone remodeling;   downregulation of bone remodeling
 narrow_synonym: inhibition of bone remodeling



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negative regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) RGD PMID:15539560 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19072540)
Ensembl
RGD
PMID:19072540 GO_REF:0000107 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286
JBrowse link
negative regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha involved_in ISO (PMID:10822112), (PMID:17241109) RGD PMID:10822112 PMID:17241109 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Cartpt CART prepropeptide involved_in ISO (PMID:16614075)
UniProtKB:P56450 (MGI:3696590|PMID:16614075)
RGD PMID:16614075 MGI:3696590 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
JBrowse link
G Cd38 CD38 molecule IDA RGD PMID:10477767 RGD:2307268 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO MGI:5560663 (MGI:5691608|PMID:25490771) RGD PMID:25490771 MGI:5691608 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Cldn18 claudin 18 acts_upstream_of_or_within ISO MGI:5007067 (MGI:5489769|PMID:22437732) RGD PMID:22437732 MGI:5489769 NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351
JBrowse link
G Csk C-terminal Src kinase IDA RGD PMID:10411542 RGD:5134371 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IMP RGD PMID:8694895 RGD:7257714 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Fshr follicle stimulating hormone receptor acts_upstream_of_or_within ISO MGI:2384087 (MGI:1926755|PMID:11089565), (MGI:3769858|PMID:17332067) RGD PMID:11089565 PMID:17332067 MGI:1926755 MGI:3769858 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
JBrowse link
G Gpr137 G protein-coupled receptor 137 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:204,129,636...204,132,622
Ensembl chr 1:204,129,636...204,133,082
JBrowse link
G Gpr137b G protein-coupled receptor 137B involved_in IBA
ISO
PMID:21873635
(MGI:6362357|PMID:31173907)
RGD PMID:31173907 PMID:21873635 MGI:6362357, RGD:13792537 NCBI chr17:86,003,630...86,041,841
Ensembl chr17:85,966,921...86,041,835
JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of_or_within ISO MGI:4351741 (MGI:5581387|PMID:24561287) RGD PMID:24561287 MGI:5581387 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Iapp islet amyloid polypeptide acts_upstream_of_or_within ISO MGI:2656235 (MGI:3037515|PMID:14970190) RGD PMID:14970190 MGI:3037515 NCBI chr 4:175,237,013...175,244,373
Ensembl chr 4:175,237,115...175,242,920
JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:5795829|PMID:11159963) RGD PMID:11159963 MGI:5795829 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
MGI:2386884 (MGI:2386137|PMID:12161749)
Ensembl
RGD
PMID:12161749 PMID:21873635 GO_REF:0000107 MGI:2386137, RGD:13792537 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080 (MGI:2667237|PMID:12677010) RGD PMID:12677010 MGI:2667237 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Tmem119 transmembrane protein 119 involved_in ISO (MGI:5543589|PMID:22416756) RGD PMID:22416756 MGI:5543589 NCBI chr12:42,828,621...42,835,678
Ensembl chr12:42,828,418...42,835,689
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B IMP
IDA
RGD PMID:11839361 PMID:16912914 RGD:730196, RGD:1624170 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5619442|PMID:23149425)
RGD PMID:23149425 PMID:21873635 MGI:5619442, RGD:13792537 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201
JBrowse link
G Vegfa vascular endothelial growth factor A IMP RGD PMID:15312247 RGD:1580559 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19818
    negative regulation of biological process 5809
      negative regulation of multicellular organismal process 1357
        negative regulation of tissue remodeling 31
          negative regulation of bone remodeling 21
            negative regulation of bone resorption 19
Path 2
Term Annotations click to browse term
  biological_process 19818
    biological regulation 13487
      regulation of biological process 13074
        negative regulation of biological process 5809
          negative regulation of multicellular organismal process 1357
            negative regulation of tissue remodeling 31
              negative regulation of bone remodeling 21
                negative regulation of bone resorption 19
paths to the root