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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of bone remodeling
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Accession:GO:0046850 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.
Synonyms:exact_synonym: regulation of bone remodelling
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa;   NCBITaxon:7742 ! Vertebrata


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regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cartpt CART prepropeptide involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15724149) Ensembl
MGI
PMID:15724149 GO_REF:0000107 NCBI chrNW_004936549:4,717,337...4,719,523
Ensembl chrNW_004936549:4,717,771...4,719,395
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chrNW_004936477:21,591,772...21,606,289
Ensembl chrNW_004936477:21,591,792...21,606,296
JBrowse link
G Gja1 gap junction protein alpha 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21346198) Ensembl
MGI
PMID:21346198 GO_REF:0000107 NCBI chrNW_004936658:3,920,043...3,932,987
Ensembl chrNW_004936658:3,920,043...3,932,987
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B acts_upstream_of_or_within ISO (PMID:21982707) MGI PMID:21982707 NCBI chrNW_004936535:5,427,131...6,168,622
Ensembl chrNW_004936535:5,794,135...6,171,072
JBrowse link
G Lep leptin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936479:15,394,966...15,411,334
Ensembl chrNW_004936479:15,394,966...15,411,334
JBrowse link
G Lepr leptin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936591:5,771,371...5,846,177
Ensembl chrNW_004936591:5,774,326...5,836,444
JBrowse link
G Mdk midkine involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936562:2,687,825...2,690,292
Ensembl chrNW_004936562:2,687,825...2,689,484
JBrowse link
G Mepe matrix extracellular phosphoglycoprotein ISO RGD PMID:10967096 RGD:70633 NCBI chrNW_004936905:284,849...297,297 JBrowse link
G Suco SUN domain containing ossification factor involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936481:14,823,622...14,892,312
Ensembl chrNW_004936481:14,823,253...14,892,318
JBrowse link
G Syt7 synaptotagmin 7 involved_in ISO (MGI:3798323|PMID:18539119) UniProt PMID:18539119 MGI:3798323 NCBI chrNW_004936581:1,516,199...1,557,992
Ensembl chrNW_004936581:1,512,855...1,559,679
JBrowse link
negative regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936673:1,394,743...1,399,726
Ensembl chrNW_004936673:1,395,757...1,396,311
JBrowse link
G Sfrp1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936785:1,276,478...1,320,397
Ensembl chrNW_004936785:1,276,420...1,321,017
JBrowse link
negative regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin related polypeptide alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936528:3,800,801...3,806,000
Ensembl chrNW_004936528:3,800,577...3,805,004
JBrowse link
G Cartpt CART prepropeptide involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936549:4,717,337...4,719,523
Ensembl chrNW_004936549:4,717,771...4,719,395
JBrowse link
G Cd38 CD38 molecule ISO RGD PMID:10477767 RGD:2307268 NCBI chrNW_004936477:12,109,761...12,156,037
Ensembl chrNW_004936477:12,108,742...12,156,248
JBrowse link
G Cldn18 claudin 18 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22437732) Ensembl
MGI
PMID:22437732 GO_REF:0000107 NCBI chrNW_004936540:373,889...401,535
Ensembl chrNW_004936540:373,889...401,535
JBrowse link
G Csk C-terminal Src kinase ISO RGD PMID:10411542 RGD:5134371 NCBI chrNW_004936471:33,757,778...33,777,871
Ensembl chrNW_004936471:33,757,772...33,778,933
JBrowse link
G Fshr follicle stimulating hormone receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11089565), (PMID:17332067) Ensembl
MGI
PMID:11089565 PMID:17332067 GO_REF:0000107 NCBI chrNW_004936508:3,601,205...3,754,234
Ensembl chrNW_004936508:3,601,315...3,753,706
JBrowse link
G Gpr137 G protein-coupled receptor 137 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936599:4,920,347...4,923,655
Ensembl chrNW_004936599:4,919,897...4,923,655
JBrowse link
G Gpr137b G protein-coupled receptor 137B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936484:16,539,076...16,578,606
Ensembl chrNW_004936484:16,542,993...16,578,612
JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24561287) Ensembl
MGI
PMID:24561287 GO_REF:0000107 NCBI chrNW_004936570:1,009,344...1,010,654
Ensembl chrNW_004936570:1,009,312...1,010,686
JBrowse link
G Iapp islet amyloid polypeptide involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14970190) Ensembl
MGI
PMID:14970190 GO_REF:0000107 NCBI chrNW_004936548:5,463,829...5,469,136
Ensembl chrNW_004936548:5,463,828...5,469,139
JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:5795829|PMID:11159963) BHF-UCL PMID:11159963 MGI:5795829 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12161749) Ensembl
TreeGrafter
MGI
PMID:12161749 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936525:4,046,609...4,154,715
Ensembl chrNW_004936525:4,048,492...4,154,618
JBrowse link
G LOC101954488 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:25490771) MGI PMID:25490771 NCBI chrNW_004936706:37,480...53,306 JBrowse link
G LOC101954950 aromatase ISO RGD PMID:8694895 RGD:7257714 NCBI chrNW_004936471:13,107,603...13,136,910
Ensembl chrNW_004936471:13,107,603...13,136,910
JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12677010) Ensembl
MGI
PMID:12677010 GO_REF:0000107 NCBI chrNW_004936558:3,106,819...3,149,689
Ensembl chrNW_004936558:3,108,283...3,149,765
JBrowse link
G Tmem119 transmembrane protein 119 involved_in ISO (MGI:5543589|PMID:22416756) ARUK-UCL PMID:22416756 MGI:5543589 NCBI chrNW_004936769:513,695...515,769 JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11b ISO RGD PMID:11839361 PMID:16912914 RGD:1624170 RGD:730196 NCBI chrNW_004936470:27,571,263...27,598,725
Ensembl chrNW_004936470:27,571,270...27,599,089
JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23149425) Ensembl
TreeGrafter
MGI
PMID:23149425 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936542:7,225,387...7,370,163
Ensembl chrNW_004936542:7,225,977...7,373,381
JBrowse link
G Vegfa vascular endothelial growth factor A ISO RGD PMID:15312247 RGD:1580559 NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673
JBrowse link
positive regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 ADAM metallopeptidase domain 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936486:19,389,925...19,403,577
Ensembl chrNW_004936486:19,391,324...19,402,332
JBrowse link
G Ahsg alpha 2-HS glycoprotein ISO RGD PMID:10500999 RGD:1625797 NCBI chrNW_004936578:3,332,934...3,339,903
Ensembl chrNW_004936578:3,332,934...3,339,903
JBrowse link
G Ca2 carbonic anhydrase 2 ISO RGD PMID:8674544 RGD:1600722 NCBI chrNW_004936544:362,591...379,151
Ensembl chrNW_004936544:362,591...380,223
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:39,664,573...39,671,532
Ensembl chrNW_004936470:39,664,511...39,671,532
JBrowse link
G Def8 differentially expressed in FDCP 8 homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936641:158,115...174,524
Ensembl chrNW_004936641:157,931...174,536
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 acts_upstream_of_or_within ISO (PMID:21308776) MGI PMID:21308776 NCBI chrNW_004936604:4,504,519...4,511,897
Ensembl chrNW_004936604:4,504,503...4,511,910
JBrowse link
G Egfr epidermal growth factor receptor ISO RGD PMID:2981075 RGD:10395245 NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528
JBrowse link
G Fshb follicle stimulating hormone subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16630814) Ensembl
MGI
PMID:16630814 GO_REF:0000107 NCBI chrNW_004936533:7,395,206...7,397,266
Ensembl chrNW_004936533:7,395,206...7,397,266
JBrowse link
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO (PMID:19834056) MGI PMID:19834056 NCBI chrNW_004936477:22,200,471...22,215,473
Ensembl chrNW_004936477:22,200,474...22,215,077
JBrowse link
G Itgb3 integrin subunit beta 3 ISO RGD PMID:8603604 RGD:5024929 NCBI chrNW_004936541:2,822,789...2,871,069
Ensembl chrNW_004936541:2,815,738...2,871,035
JBrowse link
G LOC101955076 low affinity immunoglobulin gamma Fc region receptor III-A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004937131:42,523...49,533 JBrowse link
G LOC101970551 inhibitor of carbonic anhydrase involved_in ISO (MGI:3838421|PMID:19252502) DFLAT PMID:19252502 MGI:3838421 NCBI chrNW_004936529:6,856,042...6,895,989 JBrowse link
G LOC101970831 serotransferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936529:6,917,762...6,947,512
Ensembl chrNW_004936529:6,855,958...6,947,394
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO (PMID:18505367) MGI PMID:18505367 NCBI chrNW_004936587:5,065,200...5,143,029
Ensembl chrNW_004936587:4,978,043...5,140,191
JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15878314) Ensembl
MGI
PMID:15878314 GO_REF:0000107 NCBI chrNW_004936599:3,902,903...3,918,471
Ensembl chrNW_004936599:3,902,897...3,918,471
JBrowse link
G Mc4r melanocortin 4 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:4,636,370...4,638,205
Ensembl chrNW_004936497:4,636,758...4,637,759
JBrowse link
G Oscar osteoclast associated Ig-like receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11805147) Ensembl
MGI
PMID:11805147 GO_REF:0000107 NCBI chrNW_004936994:226,318...232,143
Ensembl chrNW_004936994:226,424...312,143
JBrowse link
G Plekhm1 pleckstrin homology and RUN domain containing M1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936541:1,685,902...1,732,361
Ensembl chrNW_004936541:1,685,923...1,732,420
JBrowse link
G Ppargc1b PPARG coactivator 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936504:5,099,334...5,198,279
Ensembl chrNW_004936504:5,099,470...5,198,584
JBrowse link
G Prkca protein kinase C alpha involved_in ISO (MGI:5284791|PMID:16014375) BHF-UCL PMID:16014375 MGI:5284791 NCBI chrNW_004936541:6,231,604...6,488,201
Ensembl chrNW_004936541:6,233,110...6,488,052
JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:11792579 RGD:729815 NCBI chrNW_004936518:1,903,636...1,916,746
Ensembl chrNW_004936518:1,903,725...1,916,746
JBrowse link
G Spp1 secreted phosphoprotein 1 involved_in ISO
IEA
RGD
TreeGrafter
PMID:11792563 GO_REF:0000118 RGD:1581129 NCBI chrNW_004936905:148,956...156,023
Ensembl chrNW_004936905:148,945...156,079
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:8514886 RGD:150524326 NCBI chrNW_004936561:3,826,802...3,844,406
Ensembl chrNW_004936561:3,825,787...3,844,483
JBrowse link
G Syk spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936780:1,553,605...1,601,036
Ensembl chrNW_004936780:1,553,605...1,598,158
JBrowse link
G Tfrc transferrin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936784:696,738...728,385
Ensembl chrNW_004936784:696,713...728,543
JBrowse link
G Tmem64 transmembrane protein 64 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23395171) Ensembl
TreeGrafter
MGI
PMID:23395171 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936544:4,326,083...4,347,809
Ensembl chrNW_004936544:4,329,665...4,348,530
JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11a involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11805147) Ensembl
TreeGrafter
MGI
PMID:11805147 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936497:2,944,841...2,986,113
Ensembl chrNW_004936497:2,945,010...2,995,207
JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in ISO
IEA
RGD
Ensembl
PMID:11092398 GO_REF:0000107 RGD:730134 NCBI chrNW_004936747:1,255,803...1,288,252
Ensembl chrNW_004936747:1,255,803...1,288,252
JBrowse link
regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calcr calcitonin receptor NOT|acts_upstream_of_or_within ISO (PMID:14970190) MGI PMID:14970190 NCBI chrNW_004936803:423,558...466,762
Ensembl chrNW_004936803:422,890...466,730
JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in ISO PMID:17121910 UniProt PMID:17121910 RGD:2293713 NCBI chrNW_004936504:4,898,947...4,927,195
Ensembl chrNW_004936504:4,898,945...4,928,923
JBrowse link
G Il20ra interleukin 20 receptor subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21844205) Ensembl
MGI
PMID:21844205 GO_REF:0000107 NCBI chrNW_004936560:4,384,126...4,397,971
Ensembl chrNW_004936560:4,384,512...4,420,567
JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17053831) Ensembl
MGI
PMID:17053831 GO_REF:0000107 NCBI chrNW_004936538:3,394,623...3,596,025
Ensembl chrNW_004936538:3,398,222...3,595,261
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936585:4,701,012...4,713,421
Ensembl chrNW_004936585:4,700,418...4,714,450
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936748:1,244,962...1,250,093
Ensembl chrNW_004936748:1,245,538...1,250,093
JBrowse link
G Siglec15 sialic acid binding Ig like lectin 15 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22451653) Ensembl
TreeGrafter
MGI
PMID:22451653 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936517:945,345...960,591
Ensembl chrNW_004936517:946,341...953,674
JBrowse link
G Slc4a2 solute carrier family 4 member 2 involved_in ISO (MGI:5469753|PMID:23341620) UniProt PMID:23341620 MGI:5469753 NCBI chrNW_004936527:6,485,566...6,499,901
Ensembl chrNW_004936527:6,485,511...6,499,924
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15910
    multicellular organismal process 7390
      tissue remodeling 212
        regulation of tissue remodeling 88
          regulation of bone remodeling 66
            negative regulation of bone remodeling + 21
            positive regulation of bone remodeling 0
            regulation of bone resorption + 55
Path 2
Term Annotations click to browse term
  biological_process 15910
    biological regulation 11124
      regulation of biological process 10790
        regulation of multicellular organismal process 3010
          regulation of tissue remodeling 88
            regulation of bone remodeling 66
              negative regulation of bone remodeling + 21
              positive regulation of bone remodeling 0
              regulation of bone resorption + 55
paths to the root