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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of bone remodeling
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Accession:GO:0046850 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.
Synonyms:exact_synonym: regulation of bone remodelling
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa;   NCBITaxon:7742 ! Vertebrata


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regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cartpt CART prepropeptide involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15724149) Ensembl
MGI
PMID:15724149 GO_REF:0000107 NCBI chrNW_004624905:751,032...753,012
Ensembl chrNW_004624905:751,223...752,845
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chrNW_004624755:25,633,690...25,647,361
Ensembl chrNW_004624755:25,635,165...25,646,932
JBrowse link
G Gja1 gap junction protein alpha 1 acts_upstream_of_or_within ISO (PMID:21346198) MGI PMID:21346198 NCBI chrNW_004624798:9,358,996...9,364,413
Ensembl chrNW_004624798:9,359,004...9,364,313
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B acts_upstream_of_or_within ISO (PMID:21982707) MGI PMID:21982707 NCBI chrNW_004624853:1,350,577...2,147,616
Ensembl chrNW_004624853:1,355,384...1,868,812
JBrowse link
G Lep leptin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624783:7,708,820...7,721,610
Ensembl chrNW_004624783:7,708,588...7,721,727
JBrowse link
G Lepr leptin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624742:29,221,742...29,313,273
Ensembl chrNW_004624742:29,223,392...29,337,049
JBrowse link
G Mdk midkine involved_in ISO (MGI:5008226|PMID:21185956) UniProt PMID:21185956 MGI:5008226 NCBI chrNW_004624767:2,171,096...2,173,436
Ensembl chrNW_004624767:2,171,096...2,173,512
JBrowse link
G Mepe matrix extracellular phosphoglycoprotein ISO RGD PMID:10967096 RGD:70633 NCBI chrNW_004624872:4,345,045...4,358,456 JBrowse link
G Suco SUN domain containing ossification factor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624771:9,094,893...9,168,989
Ensembl chrNW_004624771:9,096,453...9,168,731
JBrowse link
G Syt7 synaptotagmin 7 involved_in ISO (MGI:3798323|PMID:18539119) UniProt PMID:18539119 MGI:3798323 NCBI chrNW_004624926:722,201...765,834
Ensembl chrNW_004624926:722,224...765,033
JBrowse link
negative regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chrNW_004624804:1,606,182...1,620,932
Ensembl chrNW_004624804:1,608,757...1,620,938
JBrowse link
G Sfrp1 secreted frizzled related protein 1 involved_in ISO (PMID:19072540) UniProt PMID:19072540 NCBI chrNW_004624780:2,133,105...2,172,301
Ensembl chrNW_004624780:2,132,960...2,174,508
JBrowse link
negative regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin related polypeptide alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624766:6,764,388...6,771,396
Ensembl chrNW_004624766:6,766,185...6,768,173
JBrowse link
G Cartpt CART prepropeptide involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624905:751,032...753,012
Ensembl chrNW_004624905:751,223...752,845
JBrowse link
G Cd38 CD38 molecule ISO RGD PMID:10477767 RGD:2307268 NCBI chrNW_004624755:16,035,412...16,093,610
Ensembl chrNW_004624755:16,034,771...16,093,866
JBrowse link
G Cldn18 claudin 18 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22437732) Ensembl
MGI
PMID:22437732 GO_REF:0000107 NCBI chrNW_004624730:14,500,379...14,522,047
Ensembl chrNW_004624730:14,489,585...14,522,042
JBrowse link
G Csk C-terminal Src kinase ISO RGD PMID:10411542 RGD:5134371 NCBI chrNW_004624894:12,621...29,400
Ensembl chrNW_004624894:24,203...29,668
JBrowse link
G Fshr follicle stimulating hormone receptor acts_upstream_of_or_within ISO (PMID:11089565), (PMID:17332067) MGI PMID:11089565 PMID:17332067 NCBI chrNW_004624738:30,170,514...30,369,250
Ensembl chrNW_004624738:30,176,817...30,369,166
JBrowse link
G Gpr137 G protein-coupled receptor 137 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624767:22,021,596...22,025,362
Ensembl chrNW_004624767:22,019,257...22,025,686
JBrowse link
G Gpr137b G protein-coupled receptor 137B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624775:14,333,389...14,380,869
Ensembl chrNW_004624775:14,338,028...14,380,845
JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of_or_within ISO (PMID:24561287) MGI PMID:24561287 NCBI chrNW_004624794:8,257,760...8,259,243
Ensembl chrNW_004624794:8,257,760...8,259,264
JBrowse link
G Iapp islet amyloid polypeptide involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14970190) Ensembl
MGI
PMID:14970190 GO_REF:0000107 NCBI chrNW_004624752:17,528,214...17,594,622
Ensembl chrNW_004624752:17,584,225...17,593,693
JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:5795829|PMID:11159963) BHF-UCL PMID:11159963 MGI:5795829 NCBI chrNW_004624739:7,957,709...7,963,414
Ensembl chrNW_004624739:7,957,674...7,962,318
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:12161749) MGI
TreeGrafter
PMID:12161749 GO_REF:0000118 NCBI chrNW_004624843:5,685,409...5,774,459
Ensembl chrNW_004624843:5,685,502...5,773,469
JBrowse link
G LOC101702005 aromatase ISO RGD PMID:8694895 RGD:7257714 NCBI chrNW_004624731:9,053,644...9,100,212
Ensembl chrNW_004624731:9,053,803...9,100,212
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:12677010) MGI PMID:12677010 NCBI chrNW_004624747:21,725,813...21,768,123
Ensembl chrNW_004624747:21,725,395...21,759,453
JBrowse link
G Tmem119 transmembrane protein 119 involved_in ISO (MGI:5543589|PMID:22416756) ARUK-UCL PMID:22416756 MGI:5543589 NCBI chrNW_004624747:11,828,292...11,834,855 JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11b ISO RGD PMID:11839361 PMID:16912914 RGD:1624170 RGD:730196 NCBI chrNW_004624763:17,139,109...17,166,398
Ensembl chrNW_004624763:17,138,847...17,166,453
JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing B acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:23149425) MGI
TreeGrafter
PMID:23149425 GO_REF:0000118 NCBI chrNW_004624880:2,269,247...2,427,531
Ensembl chrNW_004624880:2,270,679...2,427,298
JBrowse link
G Vegfa vascular endothelial growth factor A ISO RGD PMID:15312247 RGD:1580559 NCBI chrNW_004624754:15,929,414...15,943,637 JBrowse link
positive regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 ADAM metallopeptidase domain 8 involved_in ISO (MGI:5009349|PMID:20683884)
(MGI:5009189|PMID:11341326)
BHF-UCL PMID:11341326 PMID:20683884 MGI:5009189 MGI:5009349 NCBI chrNW_004624737:13,459,274...13,474,686 JBrowse link
G Ahsg alpha 2-HS glycoprotein ISO RGD PMID:10500999 RGD:1625797 NCBI chrNW_004624730:70,149,461...70,156,058
Ensembl chrNW_004624730:70,149,850...70,156,039
JBrowse link
G Ca2 carbonic anhydrase 2 ISO RGD PMID:8674544 RGD:1600722 NCBI chrNW_004624744:6,168,030...6,183,407
Ensembl chrNW_004624744:6,167,606...6,183,538
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624763:20,588,635...20,602,124
Ensembl chrNW_004624763:20,589,668...20,601,641
JBrowse link
G Def8 differentially expressed in FDCP 8 homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624746:99,543...119,535 JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 acts_upstream_of_or_within ISO (PMID:21308776) MGI PMID:21308776 NCBI chrNW_004624734:3,363,084...3,372,790
Ensembl chrNW_004624734:3,363,001...3,372,694
JBrowse link
G Egfr epidermal growth factor receptor ISO RGD PMID:2981075 RGD:10395245 NCBI chrNW_004624740:584,133...713,205
Ensembl chrNW_004624740:589,606...713,271
JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa involved_in ISO (MGI:5641770|PMID:25824719) UniProt PMID:25824719 MGI:5641770 NCBI chrNW_004624826:51,387...59,117 JBrowse link
G Fshb follicle stimulating hormone subunit beta acts_upstream_of_or_within ISO (PMID:16630814) MGI PMID:16630814 NCBI chrNW_004624766:19,328,730...19,332,385
Ensembl chrNW_004624766:19,329,371...19,331,267
JBrowse link
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO (PMID:19834056) MGI PMID:19834056 NCBI chrNW_004624755:26,151,302...26,169,324
Ensembl chrNW_004624755:26,154,186...26,169,365
JBrowse link
G Itgb3 integrin subunit beta 3 ISO RGD PMID:8603604 RGD:5024929 NCBI chrNW_004624849:1,895,378...1,952,755
Ensembl chrNW_004624849:1,895,914...1,952,665
JBrowse link
G LOC101719398 serotransferrin involved_in ISO (MGI:3838421|PMID:19252502) DFLAT PMID:19252502 MGI:3838421 NCBI chrNW_004624730:10,078,165...10,109,349 JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO (PMID:18505367) MGI PMID:18505367 NCBI chrNW_004624752:25,605,444...25,756,573
Ensembl chrNW_004624752:25,605,302...25,751,893
JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within ISO (PMID:15878314) MGI PMID:15878314 NCBI chrNW_004624767:20,845,949...20,861,169
Ensembl chrNW_004624767:20,845,949...20,860,673
JBrowse link
G Mc4r melanocortin 4 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624792:5,865,902...5,867,498
Ensembl chrNW_004624792:5,866,119...5,867,120
JBrowse link
G Plekhm1 pleckstrin homology and RUN domain containing M1 involved_in ISO (MGI:5806241|PMID:27777970) UniProt PMID:27777970 MGI:5806241 NCBI chrNW_004624795:37,059...86,568
Ensembl chrNW_004624795:37,059...89,135
JBrowse link
G Ppargc1b PPARG coactivator 1 beta involved_in ISO (MGI:3838421|PMID:19252502) DFLAT PMID:19252502 MGI:3838421 NCBI chrNW_004624774:9,056,138...9,178,645
Ensembl chrNW_004624774:9,056,322...9,174,388
JBrowse link
G Prkca protein kinase C alpha involved_in ISO (MGI:5284791|PMID:16014375) BHF-UCL PMID:16014375 MGI:5284791 NCBI chrNW_004624870:1,589,775...2,023,160
Ensembl chrNW_004624870:1,596,102...2,023,172
JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:11792579 RGD:729815 NCBI chrNW_004624759:14,243,887...14,259,090
Ensembl chrNW_004624759:14,244,899...14,258,445
JBrowse link
G Spp1 secreted phosphoprotein 1 involved_in ISO
IEA
RGD
TreeGrafter
PMID:11792563 GO_REF:0000118 RGD:1581129 NCBI chrNW_004624872:4,505,796...4,513,247
Ensembl chrNW_004624872:4,505,522...4,513,742
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:8514886 RGD:150524326 NCBI chrNW_004624842:2,212,561...2,260,514
Ensembl chrNW_004624842:2,211,020...2,230,132
JBrowse link
G Syk spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624868:1,654,079...1,738,648
Ensembl chrNW_004624868:1,653,997...1,701,391
JBrowse link
G Tfrc transferrin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624730:61,282,650...61,313,487
Ensembl chrNW_004624730:61,285,334...61,313,550
JBrowse link
G Tmem64 transmembrane protein 64 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:23395171) MGI
TreeGrafter
PMID:23395171 GO_REF:0000118 NCBI chrNW_004624744:1,313,662...1,348,438
Ensembl chrNW_004624744:1,313,482...1,337,753
JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11a acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:11805147) MGI
TreeGrafter
PMID:11805147 GO_REF:0000118 NCBI chrNW_004624792:8,029,383...8,087,824
Ensembl chrNW_004624792:8,029,364...8,084,424
JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in ISO (PMID:17241109) UniProt
RGD
PMID:11092398 PMID:17241109 RGD:730134 NCBI chrNW_004624748:12,527,221...12,555,551
Ensembl chrNW_004624748:12,527,478...12,555,405
JBrowse link
regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calcr calcitonin receptor NOT|acts_upstream_of_or_within ISO (PMID:14970190) MGI PMID:14970190 NCBI chrNW_004624813:233,117...357,507
Ensembl chrNW_004624813:233,042...357,396
JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in ISO PMID:17121910 UniProt PMID:17121910 RGD:2293713 NCBI chrNW_004624774:9,363,156...9,391,939
Ensembl chrNW_004624774:9,363,908...9,391,986
JBrowse link
G Il20ra interleukin 20 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:21844205) MGI PMID:21844205 NCBI chrNW_004624886:741,022...781,041
Ensembl chrNW_004624886:741,346...780,599
JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of_or_within ISO (PMID:17053831) MGI PMID:17053831 NCBI chrNW_004624875:3,636,762...3,959,991
Ensembl chrNW_004624875:3,636,924...3,956,576
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624813:2,258,279...2,270,540
Ensembl chrNW_004624813:2,258,279...2,270,824
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624857:4,143,269...4,147,877
Ensembl chrNW_004624857:4,143,270...4,147,877
JBrowse link
G Siglec15 sialic acid binding Ig like lectin 15 acts_upstream_of_or_within ISO (PMID:22451653) MGI PMID:22451653 NCBI chrNW_004624778:9,472,529...9,487,973 JBrowse link
G Slc4a2 solute carrier family 4 member 2 involved_in ISO (MGI:5469753|PMID:23341620) UniProt PMID:23341620 MGI:5469753 NCBI chrNW_004624800:5,545,380...5,560,789 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15053
    multicellular organismal process 7114
      tissue remodeling 209
        regulation of tissue remodeling 85
          regulation of bone remodeling 63
            negative regulation of bone remodeling + 20
            positive regulation of bone remodeling 0
            regulation of bone resorption + 52
Path 2
Term Annotations click to browse term
  biological_process 15053
    biological regulation 10586
      regulation of biological process 10275
        regulation of multicellular organismal process 2913
          regulation of tissue remodeling 85
            regulation of bone remodeling 63
              negative regulation of bone remodeling + 20
              positive regulation of bone remodeling 0
              regulation of bone resorption + 52
paths to the root