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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of bone remodeling
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Accession:GO:0046850 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.
Synonyms:exact_synonym: regulation of bone remodelling
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa;   NCBITaxon:7742 ! Vertebrata



show annotations for term's descendants           Sort by:
regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cartpt CART prepropeptide acts_upstream_of_or_within IMP (PMID:15724149) MGI PMID:15724149 NCBI chr13:100,034,991...100,037,191
Ensembl chr13:100,034,997...100,037,599
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 involved_in ISO MGI GO_REF:0000008 NCBI chr12:109,418,411...109,429,262
Ensembl chr12:109,418,749...109,429,262
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within IMP (PMID:20053668) MGI PMID:20053668 NCBI chr 5:33,879,068...33,894,412
Ensembl chr 5:33,879,018...33,894,412
JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within IMP (PMID:21346198) MGI PMID:21346198 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase, type II acts_upstream_of_or_within IMP (PMID:21982707) MGI PMID:21982707 NCBI chr 8:82,068,895...82,865,553
Ensembl chr 8:82,069,185...82,854,543
JBrowse link
G Lep leptin involved_in IMP (MGI:1352383|PMID:10660043) UniProt PMID:10660043 MGI:1352383 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lepr leptin receptor involved_in IMP (MGI:1352383|PMID:10660043) UniProt PMID:10660043 MGI:1352383 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549
JBrowse link
G Mdk midkine involved_in IMP (MGI:5008226|PMID:21185956) UniProt PMID:21185956 MGI:5008226 NCBI chr 2:91,760,149...91,762,348
Ensembl chr 2:91,760,150...91,762,642
JBrowse link
G Mepe matrix extracellular phosphoglycoprotein with ASARM motif (bone) ISO RGD PMID:10967096 RGD:70633 NCBI chr 5:104,473,195...104,486,477
Ensembl chr 5:104,473,195...104,486,477
JBrowse link
G Suco SUN domain containing ossification factor involved_in IMP
IBA
(MGI:4452525|PMID:20440000) UniProt
GO_Central
PMID:20440000 GO_REF:0000033 MGI:4452525 NCBI chr 1:161,643,681...161,704,506
Ensembl chr 1:161,643,683...161,704,251
JBrowse link
G Syt7 synaptotagmin VII involved_in IMP (MGI:3798323|PMID:18539119) UniProt PMID:18539119 MGI:3798323 NCBI chr19:10,366,142...10,430,545
Ensembl chr19:10,366,454...10,430,544
JBrowse link
negative regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:113,579,020...113,588,993
Ensembl chr 2:113,576,509...113,588,991
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:23,901,401...23,939,648
Ensembl chr 8:23,901,518...23,939,648
JBrowse link
negative regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin/calcitonin-related polypeptide, alpha involved_in ISO (PMID:10822112), (PMID:17241109) UniProt PMID:10822112 PMID:17241109 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
JBrowse link
G Cartpt CART prepropeptide involved_in IGI
ISO
(MGI:3696590|PMID:16614075) HGNC-UCL
MGI
PMID:16614075 GO_REF:0000119 MGI:3696590 MGI:4834177 NCBI chr13:100,034,991...100,037,191
Ensembl chr13:100,034,997...100,037,599
JBrowse link
G Cd38 CD38 antigen involved_in ISO RGD
MGI
PMID:10477767 GO_REF:0000096 MGI:4417868 RGD:2307268 NCBI chr 5:44,026,153...44,069,714
Ensembl chr 5:44,025,895...44,069,717
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 acts_upstream_of_or_within IMP (PMID:25490771) MGI PMID:25490771 NCBI chr 7:25,161,127...25,177,072
Ensembl chr 7:25,161,132...25,177,028
JBrowse link
G Cldn18 claudin 18 acts_upstream_of_or_within IMP (PMID:22437732) MGI PMID:22437732 NCBI chr 9:99,572,849...99,599,320
Ensembl chr 9:99,571,514...99,599,320
JBrowse link
G Csk c-src tyrosine kinase involved_in ISO RGD
MGI
PMID:10411542 GO_REF:0000096 MGI:4417868 RGD:5134371 NCBI chr 9:57,533,929...57,560,758
Ensembl chr 9:57,533,929...57,560,914
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 involved_in ISO RGD
MGI
PMID:8694895 GO_REF:0000096 MGI:4417868 RGD:7257714 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394
JBrowse link
G Fshr follicle stimulating hormone receptor acts_upstream_of_or_within IMP (PMID:11089565), (PMID:17332067) MGI PMID:11089565 PMID:17332067 NCBI chr17:89,292,380...89,508,103
Ensembl chr17:89,292,380...89,508,103
JBrowse link
G Gpr137 G protein-coupled receptor 137 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:6,915,425...6,919,818
Ensembl chr19:6,915,425...6,919,848
JBrowse link
G Gpr137b G protein-coupled receptor 137B involved_in IMP
IBA
(MGI:6362357|PMID:31173907) UniProt
GO_Central
PMID:31173907 GO_REF:0000033 MGI:6362357 NCBI chr13:13,528,035...13,568,250
Ensembl chr13:13,532,205...13,568,599
JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of_or_within IMP (PMID:24561287) MGI PMID:24561287 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457
JBrowse link
G Iapp islet amyloid polypeptide acts_upstream_of_or_within IMP (PMID:14970190) MGI PMID:14970190 NCBI chr 6:142,244,151...142,249,546
Ensembl chr 6:142,244,149...142,249,687
JBrowse link
G Il6 interleukin 6 involved_in IMP (MGI:5795829|PMID:11159963) BHF-UCL PMID:11159963 MGI:5795829 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D acts_upstream_of_or_within
involved_in
IMP
IBA
(PMID:12161749) MGI
GO_Central
PMID:12161749 GO_REF:0000033 NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229
JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 acts_upstream_of_or_within IMP (PMID:12677010) MGI PMID:12677010 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495
JBrowse link
G Tmem119 transmembrane protein 119 involved_in IMP (MGI:5543589|PMID:22416756) ARUK-UCL PMID:22416756 MGI:5543589 NCBI chr 5:113,931,790...113,938,457
Ensembl chr 5:113,931,790...113,938,577
JBrowse link
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) involved_in ISO RGD
MGI
PMID:11839361 PMID:16912914 GO_REF:0000096 MGI:4417868 RGD:1624170 RGD:730196 NCBI chr15:54,114,014...54,141,700
Ensembl chr15:54,114,015...54,141,880
JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B acts_upstream_of_or_within
involved_in
IMP
IBA
(PMID:23149425) MGI
GO_Central
PMID:23149425 GO_REF:0000033 NCBI chr 9:40,922,056...41,069,358
Ensembl chr 9:40,922,394...41,072,993
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO RGD
MGI
PMID:15312247 GO_REF:0000096 MGI:4417868 RGD:1580559 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
positive regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 a disintegrin and metallopeptidase domain 8 involved_in IDA
IMP
(MGI:5009189|PMID:11341326)
(MGI:5009349|PMID:20683884)
BHF-UCL PMID:11341326 PMID:20683884 MGI:5009189 MGI:5009349 NCBI chr 7:139,558,845...139,573,016
Ensembl chr 7:139,558,845...139,572,475
JBrowse link
G Ahsg alpha-2-HS-glycoprotein involved_in ISO RGD
MGI
PMID:10500999 GO_REF:0000096 MGI:4417868 RGD:1625797 NCBI chr16:22,710,793...22,718,193
Ensembl chr16:22,710,027...22,718,199
JBrowse link
G Car2 carbonic anhydrase 2 involved_in ISO RGD
MGI
PMID:8674544 GO_REF:0000096 MGI:4417868 RGD:1600722 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein involved_in IMP (MGI:3588832|PMID:16061724), (MGI:5426134|PMID:17164993), (MGI:5426135|PMID:16937266) UniProt PMID:16061724 PMID:16937266 PMID:17164993 MGI:3588832 MGI:5426134 MGI:5426135 NCBI chr15:39,609,326...39,624,334
Ensembl chr15:39,609,326...39,624,334
JBrowse link
G Def8 differentially expressed in FDCP 8 involved_in IMP (MGI:5806241|PMID:27777970) UniProt PMID:27777970 MGI:5806241 NCBI chr 8:124,169,725...124,190,009
Ensembl chr 8:124,150,266...124,190,009
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 acts_upstream_of_or_within
involved_in
IMP
ISO
(PMID:21308776) MGI PMID:21308776 GO_REF:0000008 NCBI chr12:109,418,411...109,429,262
Ensembl chr12:109,418,749...109,429,262
JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO RGD
MGI
PMID:2981075 GO_REF:0000096 MGI:4417868 RGD:10395245 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Fcgr4 Fc receptor, IgG, low affinity IV involved_in IMP (MGI:5641770|PMID:25824719) UniProt PMID:25824719 MGI:5641770 NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330
JBrowse link
G Fshb follicle stimulating hormone beta acts_upstream_of_or_within IMP (PMID:16630814) MGI PMID:16630814 NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001
JBrowse link
G Idua iduronidase, alpha-L acts_upstream_of_or_within IMP (PMID:19834056) MGI PMID:19834056 NCBI chr 5:108,808,197...108,833,312
Ensembl chr 5:108,808,197...108,832,423
JBrowse link
G Itgb3 integrin beta 3 involved_in IC
ISO
(MGI:3766172|PMID:16995821) BHF-UCL
MGI
RGD
PMID:8603604 PMID:16995821 GO_REF:0000096 MGI:3766172 MGI:4417868 RGD:5024929 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
JBrowse link
G Lrp6 low density lipoprotein receptor-related protein 6 acts_upstream_of_or_within IMP (PMID:18505367) MGI PMID:18505367 NCBI chr 6:134,423,439...134,543,876
Ensembl chr 6:134,423,439...134,543,928
JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within IMP (PMID:15878314) MGI PMID:15878314 NCBI chr19:5,790,928...5,808,564
Ensembl chr19:5,790,932...5,808,560
JBrowse link
G Mc4r melanocortin 4 receptor involved_in IMP
ISO
(MGI:3696590|PMID:16614075) HGNC-UCL
MGI
PMID:16614075 GO_REF:0000119 MGI:3696590 MGI:4834177 NCBI chr18:66,990,776...66,993,558
Ensembl chr18:66,990,775...66,993,577
JBrowse link
G Mir9718 microRNA 9718 acts_upstream_of_or_within IMP (PMID:25019593) MGI PMID:25019593 NCBI chr12:73,092,659...73,092,722
Ensembl chr12:73,092,659...73,092,722
JBrowse link
G Oscar osteoclast associated receptor acts_upstream_of_or_within IMP (PMID:11805147) MGI PMID:11805147 NCBI chr 7:3,612,812...3,619,156
Ensembl chr 7:3,612,812...3,619,156
JBrowse link
G Plekhm1 pleckstrin homology domain containing, family M (with RUN domain) member 1 involved_in IMP (MGI:5806241|PMID:27777970) UniProt PMID:27777970 MGI:5806241 NCBI chr11:103,255,101...103,303,531
Ensembl chr11:103,255,101...103,303,513
JBrowse link
G Ppargc1b peroxisome proliferative activated receptor, gamma, coactivator 1 beta involved_in IMP (MGI:3838421|PMID:19252502) DFLAT PMID:19252502 MGI:3838421 NCBI chr18:61,424,516...61,533,846
Ensembl chr18:61,431,207...61,533,502
JBrowse link
G Prkca protein kinase C, alpha involved_in IMP (MGI:5284791|PMID:16014375) BHF-UCL PMID:16014375 MGI:5284791 NCBI chr11:107,824,213...108,237,360
Ensembl chr11:107,824,213...108,234,754
JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) involved_in ISO RGD
MGI
PMID:11792579 GO_REF:0000096 MGI:4417868 RGD:729815 NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668
JBrowse link
G Spp1 secreted phosphoprotein 1 involved_in ISO
IBA
RGD
GO_Central
MGI
PMID:11792563 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:1581129 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916
JBrowse link
G Src Rous sarcoma oncogene involved_in ISO RGD
MGI
PMID:8514886 GO_REF:0000096 MGI:4417868 RGD:150524326 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
JBrowse link
G Syk spleen tyrosine kinase involved_in IMP (MGI:3703840|PMID:17353363) UniProt PMID:17353363 MGI:3703840 NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828
JBrowse link
G Tfrc transferrin receptor involved_in IDA (MGI:3838421|PMID:19252502) DFLAT PMID:19252502 MGI:3838421 NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612
JBrowse link
G Tmem64 transmembrane protein 64 involved_in
acts_upstream_of_or_within
IBA
IMP
(PMID:23395171) GO_Central
MGI
PMID:23395171 GO_REF:0000033 NCBI chr 4:15,265,820...15,286,753
Ensembl chr 4:15,265,831...15,286,753
JBrowse link
G Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a, NFKB activator acts_upstream_of_or_within
involved_in
IMP
IBA
(PMID:11805147) MGI
GO_Central
PMID:11805147 GO_REF:0000033 NCBI chr 1:105,708,443...105,777,172
Ensembl chr 1:105,708,443...105,775,709
JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 involved_in ISO RGD
MGI
PMID:11092398 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:730134 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483
JBrowse link
G Trf transferrin involved_in IDA (MGI:3838421|PMID:19252502) DFLAT PMID:19252502 MGI:3838421 NCBI chr 9:103,086,075...103,107,485
Ensembl chr 9:103,081,200...103,107,643
JBrowse link
regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calcr calcitonin receptor NOT|acts_upstream_of_or_within IMP (PMID:14970190) MGI PMID:14970190 NCBI chr 6:3,685,678...3,764,713
Ensembl chr 6:3,685,680...3,764,714
JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221
JBrowse link
G Il20ra interleukin 20 receptor, alpha acts_upstream_of_or_within IMP (PMID:21844205) MGI PMID:21844205 NCBI chr10:19,587,421...19,635,801
Ensembl chr10:19,588,318...19,635,801
JBrowse link
G Itgav integrin alpha V involved_in TAS (MGI:5284791|PMID:16014375) BHF-UCL PMID:16014375 MGI:5284791 NCBI chr 2:83,554,796...83,637,261
Ensembl chr 2:83,554,741...83,637,260
JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of_or_within IMP (PMID:17053831) MGI PMID:17053831 NCBI chr11:79,223,541...79,472,435
Ensembl chr11:79,230,519...79,472,438
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 involved_in IMP (MGI:5303050|PMID:21803180) UniProt PMID:21803180 MGI:5303050 NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 involved_in IMP (MGI:3839226|PMID:19204730) UniProt PMID:19204730 MGI:3839226 NCBI chr 3:115,504,082...115,508,704
Ensembl chr 3:115,504,082...115,508,721
JBrowse link
G Siglec15 sialic acid binding Ig-like lectin 15 acts_upstream_of_or_within
involved_in
IMP
IBA
(PMID:22451653) MGI
GO_Central
PMID:22451653 GO_REF:0000033 NCBI chr18:78,085,708...78,100,656
Ensembl chr18:78,086,829...78,100,610
JBrowse link
G Slc4a2 solute carrier family 4 (anion exchanger), member 2 involved_in IMP (MGI:5469753|PMID:23341620) UniProt PMID:23341620 MGI:5469753 NCBI chr 5:24,628,834...24,645,945
Ensembl chr 5:24,628,835...24,645,948
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28580
    multicellular organismal process 8935
      tissue remodeling 231
        regulation of tissue remodeling 90
          regulation of bone remodeling 67
            negative regulation of bone remodeling + 21
            positive regulation of bone remodeling 0
            regulation of bone resorption + 56
Path 2
Term Annotations click to browse term
  biological_process 28580
    biological regulation 13143
      regulation of biological process 12752
        regulation of multicellular organismal process 3543
          regulation of tissue remodeling 90
            regulation of bone remodeling 67
              negative regulation of bone remodeling + 21
              positive regulation of bone remodeling 0
              regulation of bone resorption + 56
paths to the root