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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of bone remodeling
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Accession:GO:0046850 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.
Synonyms:exact_synonym: regulation of bone remodelling
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa;   NCBITaxon:7742 ! Vertebrata



show annotations for term's descendants           Sort by:
regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARTPT CART prepropeptide involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15724149) Ensembl
MGI
PMID:15724149 GO_REF:0000107 NCBI chr 5:71,719,275...71,721,045
Ensembl chr 5:71,719,275...71,721,048
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,293...1,808,872
JBrowse link
G GJA1 gap junction protein alpha 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21346198) Ensembl
MGI
PMID:21346198 GO_REF:0000107 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G INPP4B inositol polyphosphate-4-phosphatase type II B acts_upstream_of_or_within ISO (PMID:21982707) MGI PMID:21982707 NCBI chr 4:142,023,160...142,846,535
Ensembl chr 4:142,023,160...142,847,432
JBrowse link
G LEP leptin involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LEPR leptin receptor involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
JBrowse link
G MDK midkine involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr11:46,380,784...46,383,837
Ensembl chr11:46,380,756...46,383,837
JBrowse link
G MEPE matrix extracellular phosphoglycoprotein ISO RGD PMID:10967096 RGD:70633 NCBI chr 4:87,821,398...87,846,792
Ensembl chr 4:87,821,398...87,846,814
JBrowse link
G SUCO SUN domain containing ossification factor involved_in IEA
IBA
ISS
Ensembl
GO_Central
UniProt
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:172,532,349...172,611,833
Ensembl chr 1:172,532,349...172,611,833
JBrowse link
G SYT7 synaptotagmin 7 involved_in ISS UniProt GO_REF:0000024 NCBI chr11:61,513,714...61,588,387
Ensembl chr11:61,513,714...61,581,148
JBrowse link
negative regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IMP (PMID:15539560) BHF-UCL PMID:15539560 NCBI chr15:32,718,004...32,745,106
Ensembl chr15:32,718,004...32,745,106
JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IMP (PMID:19072540) UniProt PMID:19072540 NCBI chr 8:41,261,962...41,309,473
Ensembl chr 8:41,261,962...41,309,473
JBrowse link
negative regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALCA calcitonin related polypeptide alpha involved_in IDA (PMID:10822112), (PMID:17241109) UniProt PMID:10822112 PMID:17241109 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354
JBrowse link
G CARTPT CART prepropeptide involved_in IMP
IEA
(PMID:16614075) HGNC-UCL
Ensembl
PMID:16614075 GO_REF:0000107 NCBI chr 5:71,719,275...71,721,045
Ensembl chr 5:71,719,275...71,721,048
JBrowse link
G CD38 CD38 molecule involved_in ISO
IEA
RGD
Ensembl
PMID:10477767 GO_REF:0000107 RGD:2307268 NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232
JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:25490771) MGI PMID:25490771 NCBI chr19:42,507,306...42,528,481
Ensembl chr19:42,507,304...42,561,234
JBrowse link
G CLDN18 claudin 18 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22437732) Ensembl
MGI
PMID:22437732 GO_REF:0000107 NCBI chr 3:137,998,816...138,033,649
Ensembl chr 3:137,998,735...138,033,655
JBrowse link
G CSK C-terminal Src kinase involved_in ISO
IEA
RGD
Ensembl
PMID:10411542 GO_REF:0000107 RGD:5134371 NCBI chr15:74,782,080...74,803,197
Ensembl chr15:74,782,080...74,803,197
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 ISO RGD PMID:8694895 RGD:7257714 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
JBrowse link
G FSHR follicle stimulating hormone receptor acts_upstream_of_or_within ISO (PMID:11089565), (PMID:17332067) MGI PMID:11089565 PMID:17332067 NCBI chr 2:48,962,157...49,154,515
Ensembl chr 2:48,962,157...49,154,527
JBrowse link
G GPR137 G protein-coupled receptor 137 involved_in IBA
IEA
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr11:64,270,531...64,289,500
Ensembl chr11:64,270,062...64,289,494
JBrowse link
G GPR137B G protein-coupled receptor 137B involved_in ISS
IEA
IBA
UniProt
TreeGrafter
GO_Central
GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:236,142,539...236,208,907
Ensembl chr 1:236,142,505...236,221,865
JBrowse link
G HAMP hepcidin antimicrobial peptide involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24561287) Ensembl
MGI
PMID:24561287 GO_REF:0000107 NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143
JBrowse link
G IAPP islet amyloid polypeptide involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14970190) Ensembl
MGI
PMID:14970190 GO_REF:0000107 NCBI chr12:21,354,959...21,379,980
Ensembl chr12:21,354,959...21,379,980
JBrowse link
G IL6 interleukin 6 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(PMID:12161749) Ensembl
MGI
GO_Central
PMID:12161749 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:233,060,342...233,207,903
Ensembl chr 2:233,059,967...233,207,903
JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
(PMID:12677010) BHF-UCL
MGI
Ensembl
PMID:12677010 GO_REF:0000024 GO_REF:0000107 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032
JBrowse link
G TMEM119 transmembrane protein 119 involved_in IEA
ISS
Ensembl
ARUK-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr12:108,589,851...108,598,084
Ensembl chr12:108,589,851...108,598,320
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in NAS (PMID:21127049) BHF-UCL PMID:21127049 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314
JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b involved_in ISO
IEA
RGD
Ensembl
PMID:11839361 PMID:16912914 GO_REF:0000107 RGD:1624170 RGD:730196 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885
JBrowse link
G UBASH3B ubiquitin associated and SH3 domain containing B involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(PMID:23149425) Ensembl
MGI
GO_Central
PMID:23149425 GO_REF:0000033 GO_REF:0000107 NCBI chr11:122,655,722...122,814,473
Ensembl chr11:122,655,722...122,814,473
JBrowse link
G VEGFA vascular endothelial growth factor A ISO RGD PMID:15312247 RGD:1580559 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
positive regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM8 ADAM metallopeptidase domain 8 involved_in ISS
IEA
BHF-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr10:133,262,423...133,276,868
Ensembl chr10:133,262,420...133,276,868
JBrowse link
G AHSG alpha 2-HS glycoprotein ISO RGD PMID:10500999 RGD:1625797 NCBI chr 3:186,613,060...186,621,318
Ensembl chr 3:186,613,060...186,621,318
JBrowse link
G CA2 carbonic anhydrase 2 ISO RGD PMID:8674544 RGD:1600722 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493
JBrowse link
G DCSTAMP dendrocyte expressed seven transmembrane protein involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 8:104,339,796...104,356,689
Ensembl chr 8:104,339,087...104,356,689
JBrowse link
G DEF8 differentially expressed in FDCP 8 homolog involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr16:89,948,755...89,968,060
Ensembl chr16:89,948,697...89,968,060
JBrowse link
G DLK1 delta like non-canonical Notch ligand 1 acts_upstream_of_or_within ISO (PMID:21308776) MGI PMID:21308776 NCBI chr14:100,726,892...100,738,224
Ensembl chr14:100,725,705...100,738,224
JBrowse link
G EGFR epidermal growth factor receptor involved_in ISO
IEA
RGD
Ensembl
PMID:2981075 GO_REF:0000107 RGD:10395245 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G FCGR3A Fc gamma receptor IIIa involved_in ISO (MGI:5641770|PMID:25824719) UniProt PMID:25824719 MGI:5641770 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,968
JBrowse link
G FSHB follicle stimulating hormone subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16630814) Ensembl
MGI
PMID:16630814 GO_REF:0000107 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261
JBrowse link
G IDUA alpha-L-iduronidase acts_upstream_of_or_within ISO (PMID:19834056) MGI PMID:19834056 NCBI chr 4:986,997...1,008,351
Ensembl chr 4:986,997...1,004,564
JBrowse link
G ITGB3 integrin subunit beta 3 involved_in ISO
IEA
RGD
Ensembl
PMID:8603604 GO_REF:0000107 RGD:5024929 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743
JBrowse link
G LRP6 LDL receptor related protein 6 acts_upstream_of_or_within ISO (PMID:18505367) MGI PMID:18505367 NCBI chr12:12,116,025...12,267,044
Ensembl chr12:12,116,025...12,267,044
JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15878314) Ensembl
MGI
PMID:15878314 GO_REF:0000107 NCBI chr11:65,538,559...65,558,359
Ensembl chr11:65,538,559...65,558,930
JBrowse link
G MC4R melanocortin 4 receptor involved_in IEA
IMP
(PMID:16614075) Ensembl
HGNC-UCL
PMID:16614075 GO_REF:0000107 NCBI chr18:60,371,062...60,372,775
Ensembl chr18:60,371,062...60,372,775
JBrowse link
G OSCAR osteoclast associated Ig-like receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11805147) Ensembl
MGI
PMID:11805147 GO_REF:0000107 NCBI chr19:54,094,668...54,100,803
Ensembl chr19:54,094,668...54,102,692
JBrowse link
G PLEKHM1 pleckstrin homology and RUN domain containing M1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr17:45,434,209...45,490,721
Ensembl chr17:45,435,900...45,490,758
JBrowse link
G PPARGC1B PPARG coactivator 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:149,730,310...149,857,959
Ensembl chr 5:149,730,298...149,855,022
JBrowse link
G PRKCA protein kinase C alpha involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743
JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:11792579 RGD:729815 NCBI chr 5:40,679,915...40,746,800
Ensembl chr 5:40,679,915...40,693,735
JBrowse link
G SPP1 secreted phosphoprotein 1 involved_in ISO
IEA
IBA
RGD
TreeGrafter
GO_Central
Ensembl
PMID:11792563 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:1581129 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO
IEA
RGD
Ensembl
PMID:8514886 GO_REF:0000107 RGD:150524326 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G SYK spleen associated tyrosine kinase involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549
JBrowse link
G TF transferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641
JBrowse link
G TFRC transferrin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153
JBrowse link
G TMEM64 transmembrane protein 64 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(PMID:23395171) Ensembl
TreeGrafter
MGI
GO_Central
PMID:23395171 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:90,621,995...90,646,083
Ensembl chr 8:90,621,995...90,791,632
JBrowse link
G TNFRSF11A TNF receptor superfamily member 11a involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(PMID:11805147) Ensembl
MGI
GO_Central
PMID:11805147 GO_REF:0000033 GO_REF:0000107 NCBI chr18:62,325,310...62,391,288
Ensembl chr18:62,325,287...62,391,288
JBrowse link
G TNFSF11 TNF superfamily member 11 involved_in ISO
IDA
(PMID:17241109) RGD
UniProt
PMID:11092398 PMID:17241109 RGD:730134 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013
JBrowse link
regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BGLAP bone gamma-carboxyglutamate protein involved_in NAS (PMID:10486212) UniProt PMID:10486212 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G CALCR calcitonin receptor NOT|acts_upstream_of_or_within ISO (PMID:14970190) MGI PMID:14970190 NCBI chr 7:93,424,486...93,574,724
Ensembl chr 7:93,424,486...93,574,730
JBrowse link
G CSF1R colony stimulating factor 1 receptor involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
JBrowse link
G IL20RA interleukin 20 receptor subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21844205) Ensembl
MGI
PMID:21844205 GO_REF:0000107 NCBI chr 6:136,999,971...137,044,965
Ensembl chr 6:136,999,971...137,045,180
JBrowse link
G ITGB3 integrin subunit beta 3 involved_in TAS (PMID:19267251) BHF-UCL PMID:19267251 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,827...47,313,743
JBrowse link
G NF1 neurofibromin 1 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
(PMID:17053831) HGNC-UCL
MGI
Ensembl
PMID:17053831 GO_REF:0000024 GO_REF:0000107 NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116
JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516
JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:101,236,899...101,242,313
Ensembl chr 1:101,236,865...101,243,713
JBrowse link
G SIGLEC15 sialic acid binding Ig like lectin 15 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(PMID:22451653) Ensembl
MGI
GO_Central
PMID:22451653 GO_REF:0000033 GO_REF:0000107 NCBI chr18:45,825,675...45,844,094
Ensembl chr18:45,825,675...45,844,094
JBrowse link
G SLC4A2 solute carrier family 4 member 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:151,058,200...151,076,527
Ensembl chr 7:151,057,210...151,076,526
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in TAS (PMID:19267251) BHF-UCL PMID:19267251 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19654
    multicellular organismal process 8480
      tissue remodeling 253
        regulation of tissue remodeling 114
          regulation of bone remodeling 67
            negative regulation of bone remodeling + 22
            positive regulation of bone remodeling 0
            regulation of bone resorption + 56
Path 2
Term Annotations click to browse term
  biological_process 19654
    biological regulation 13379
      regulation of biological process 12995
        regulation of multicellular organismal process 3591
          regulation of tissue remodeling 114
            regulation of bone remodeling 67
              negative regulation of bone remodeling + 22
              positive regulation of bone remodeling 0
              regulation of bone resorption + 56
paths to the root