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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of bone remodeling
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Accession:GO:0046850 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.
Synonyms:exact_synonym: regulation of bone remodelling
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa;   NCBITaxon:7742 ! Vertebrata


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regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARTPT CART prepropeptide involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15724149) Ensembl
MGI
PMID:15724149 GO_REF:0000107 NCBI chr 4:66,058,755...66,060,635
Ensembl chr 4:66,058,769...66,061,112
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chr27:46,958,444...46,974,032
Ensembl chr27:46,957,254...46,973,392
JBrowse link
G GJA1 gap junction protein alpha 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21346198) Ensembl
MGI
PMID:21346198 GO_REF:0000107 NCBI chr13:52,397,291...52,410,341
Ensembl chr13:52,396,109...52,410,339
JBrowse link
G INPP4B inositol polyphosphate-4-phosphatase type II B acts_upstream_of_or_within ISO (PMID:21982707) MGI PMID:21982707 NCBI chr 7:88,929,249...89,732,375
Ensembl chr 7:88,979,493...89,461,475
JBrowse link
G LEP leptin involved_in ISO (MGI:1352383|PMID:10660043) UniProt PMID:10660043 MGI:1352383 NCBI chr21:97,056,913...97,071,161
Ensembl chr21:97,057,529...97,071,220
JBrowse link
G LEPR leptin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:67,454,205...67,567,524
Ensembl chr20:67,454,334...67,524,229
JBrowse link
G MDK midkine involved_in ISO (MGI:5008226|PMID:21185956) UniProt PMID:21185956 MGI:5008226 NCBI chr 1:18,945,355...18,948,394
Ensembl chr 1:18,946,378...18,947,134
JBrowse link
G MEPE matrix extracellular phosphoglycoprotein ISO RGD PMID:10967096 RGD:70633 NCBI chr 7:36,201,916...36,216,446 JBrowse link
G SUCO SUN domain containing ossification factor involved_in ISO (MGI:4452525|PMID:20440000) UniProt PMID:20440000 MGI:4452525 NCBI chr25:56,541,074...56,623,086
Ensembl chr25:56,541,038...56,623,201
JBrowse link
G SYT7 synaptotagmin 7 involved_in ISO (MGI:3798323|PMID:18539119) UniProt PMID:18539119 MGI:3798323 NCBI chr 1:12,267,591...12,333,181
Ensembl chr 1:12,267,685...12,333,185
JBrowse link
negative regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GREM1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chr26:50,152,097...50,169,760 JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 Ensembl chr26:50,155,496...50,156,047 JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:39,243,775...39,289,050
Ensembl chr 8:39,243,780...39,288,984
JBrowse link
negative regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARTPT CART prepropeptide involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:66,058,755...66,060,635
Ensembl chr 4:66,058,769...66,061,112
JBrowse link
G CD38 CD38 molecule ISO RGD PMID:10477767 RGD:2307268 NCBI chr27:34,375,859...34,449,131
Ensembl chr27:34,376,271...34,449,425
JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:25490771) MGI PMID:25490771 NCBI chr 6:36,708,368...36,731,729
Ensembl chr 6:36,708,311...36,730,189
JBrowse link
G CLDN18 claudin 18 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22437732) Ensembl
MGI
PMID:22437732 GO_REF:0000107 NCBI chr15:52,509,568...52,533,205
Ensembl chr15:52,508,887...52,532,836
JBrowse link
G CSK C-terminal Src kinase ISO RGD PMID:10411542 RGD:5134371 NCBI chr26:8,667,657...8,688,850
Ensembl chr26:8,667,655...8,688,824
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 ISO RGD PMID:8694895 RGD:7257714 NCBI chr26:32,074,260...32,164,926
Ensembl chr26:32,132,425...32,164,277
JBrowse link
G FSHR follicle stimulating hormone receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11089565), (PMID:17332067) Ensembl
MGI
PMID:11089565 PMID:17332067 GO_REF:0000107 NCBI chr14:58,013,405...58,211,528
Ensembl chr14:58,013,742...58,212,755
JBrowse link
G GPR137 G protein-coupled receptor 137 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:9,944,971...9,949,623
Ensembl chr 1:9,944,579...9,949,624
JBrowse link
G GPR137B G protein-coupled receptor 137B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr25:73,301,915...73,371,209
Ensembl chr25:73,302,046...73,372,569
JBrowse link
G HAMP hepcidin antimicrobial peptide involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24561287) Ensembl
MGI
PMID:24561287 GO_REF:0000107 NCBI chr 6:30,214,820...30,218,100
Ensembl chr 6:30,215,563...30,217,996
JBrowse link
G IAPP islet amyloid polypeptide involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14970190) Ensembl
MGI
PMID:14970190 GO_REF:0000107 NCBI chr11:21,240,947...21,247,409
Ensembl chr11:21,241,514...21,247,207
JBrowse link
G IL6 interleukin 6 involved_in ISO (MGI:5795829|PMID:11159963) BHF-UCL PMID:11159963 MGI:5795829 NCBI chr21:35,577,513...35,582,385
Ensembl chr21:35,577,939...35,582,237
JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D acts_upstream_of_or_within ISO (PMID:12161749) MGI PMID:12161749 NCBI chr10:119,093,160...119,244,128
Ensembl chr10:119,093,781...119,244,123
JBrowse link
G LOC103239768 calcitonin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:49,946,574...49,956,010
Ensembl chr 1:49,951,694...49,954,092
JBrowse link
G P2RX7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:12677010) MGI PMID:12677010 NCBI chr11:116,505,975...116,560,151
Ensembl chr11:116,529,346...116,563,059
JBrowse link
G TMEM119 transmembrane protein 119 involved_in ISO (MGI:5543589|PMID:22416756) ARUK-UCL PMID:22416756 MGI:5543589 NCBI chr11:103,787,911...103,796,217
Ensembl chr11:103,788,407...103,789,249
JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b ISO RGD PMID:11839361 PMID:16912914 RGD:1624170 RGD:730196 NCBI chr 8:113,520,711...113,549,370
Ensembl chr 8:113,520,596...113,548,936
JBrowse link
G UBASH3B ubiquitin associated and SH3 domain containing B acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:23149425) MGI
TreeGrafter
PMID:23149425 GO_REF:0000118 NCBI chr 1:114,053,792...114,218,909
Ensembl chr 1:114,054,384...114,218,912
JBrowse link
G VEGFA vascular endothelial growth factor A ISO RGD PMID:15312247 RGD:1580559 NCBI chr17:28,377,959...28,394,508 JBrowse link
positive regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM8 ADAM metallopeptidase domain 8 involved_in ISO (MGI:5009189|PMID:11341326)
(MGI:5009349|PMID:20683884)
BHF-UCL PMID:11341326 PMID:20683884 MGI:5009189 MGI:5009349 NCBI chr26:53,114,184...53,129,650
Ensembl chr26:53,114,924...53,126,900
JBrowse link
G AHSG alpha 2-HS glycoprotein ISO RGD PMID:10500999 RGD:1625797 NCBI chr15:2,809,234...2,818,382
Ensembl chr15:2,809,028...2,817,514
JBrowse link
G CA2 carbonic anhydrase 2 ISO RGD PMID:8674544 RGD:1600722 NCBI chr 8:80,830,963...80,848,245
Ensembl chr 8:80,830,939...80,848,707
JBrowse link
G DCSTAMP dendrocyte expressed seven transmembrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:99,174,778...99,193,539
Ensembl chr 8:99,185,423...99,193,058
JBrowse link
G DEF8 differentially expressed in FDCP 8 homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:75,274,379...75,294,458
Ensembl chr 5:75,275,190...75,295,178
JBrowse link
G DLK1 delta like non-canonical Notch ligand 1 acts_upstream_of_or_within ISO (PMID:21308776) MGI PMID:21308776 NCBI chr24:78,687,542...78,695,782
Ensembl chr24:78,687,668...78,695,607
JBrowse link
G EGFR epidermal growth factor receptor ISO RGD PMID:2981075 RGD:10395245 NCBI chr21:3,664,622...3,853,492
Ensembl chr21:3,666,339...3,853,239
JBrowse link
G FCGR3A Fc fragment of IgG receptor IIIa involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:2,466,492...2,475,579 JBrowse link
G FSHB follicle stimulating hormone subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16630814) Ensembl
MGI
PMID:16630814 GO_REF:0000107 NCBI chr 1:34,943,544...34,947,796
Ensembl chr 1:34,943,568...34,946,863
JBrowse link
G IDUA alpha-L-iduronidase acts_upstream_of_or_within ISO (PMID:19834056) MGI PMID:19834056 NCBI chr27:47,778,220...47,794,435
Ensembl chr27:47,778,335...47,794,352
JBrowse link
G ITGB3 integrin subunit beta 3 ISO RGD PMID:8603604 RGD:5024929 NCBI chr16:59,372,171...59,431,434
Ensembl chr16:59,374,889...59,410,857
JBrowse link
G LRP6 LDL receptor related protein 6 acts_upstream_of_or_within ISO (PMID:18505367) MGI PMID:18505367 NCBI chr11:12,016,542...12,170,496
Ensembl chr11:12,021,560...12,170,663
JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15878314) Ensembl
MGI
PMID:15878314 GO_REF:0000107 NCBI chr 1:8,681,140...8,700,721
Ensembl chr 1:8,681,156...8,703,740
JBrowse link
G MC4R melanocortin 4 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:19,380,054...19,386,412
Ensembl chr18:19,380,849...19,381,847
JBrowse link
G OSCAR osteoclast associated Ig-like receptor acts_upstream_of_or_within ISO (PMID:11805147) MGI PMID:11805147 NCBI chr 6:46,772,335...46,777,606 JBrowse link
G PLEKHM1 pleckstrin homology and RUN domain containing M1 involved_in ISO (MGI:5806241|PMID:27777970) UniProt PMID:27777970 MGI:5806241 NCBI chr16:60,926,006...60,980,359
Ensembl chr16:60,926,063...60,980,669
JBrowse link
G PPARGC1B PPARG coactivator 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:52,337,802...52,462,553
Ensembl chr23:52,428,052...52,455,089
JBrowse link
G PRKCA protein kinase C alpha involved_in ISO (MGI:5284791|PMID:16014375) BHF-UCL PMID:16014375 MGI:5284791 NCBI chr16:54,638,548...55,144,372
Ensembl chr16:54,642,729...54,948,256
JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:11792579 RGD:729815 NCBI chr 4:39,440,697...39,453,983
Ensembl chr 4:39,440,276...39,454,004
JBrowse link
G SPP1 secreted phosphoprotein 1 ISO RGD PMID:11792563 RGD:1581129 NCBI chr 7:36,337,165...36,344,927
Ensembl chr 7:36,338,386...36,344,407
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:8514886 RGD:150524326 NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776
JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:101,254,085...101,374,724
Ensembl chr12:101,260,061...101,349,856
JBrowse link
G TF transferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:56,586,311...56,618,304
Ensembl chr15:56,586,104...56,618,149
JBrowse link
G TFRC transferrin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:91,102,153...91,134,994
Ensembl chr15:91,102,817...91,135,584
JBrowse link
G TMEM64 transmembrane protein 64 acts_upstream_of_or_within ISO (PMID:23395171) MGI PMID:23395171 NCBI chr 8:85,706,631...85,730,966 JBrowse link
G TNFRSF11A TNF receptor superfamily member 11a involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11805147) Ensembl
MGI
PMID:11805147 GO_REF:0000107 NCBI chr18:17,385,251...17,446,442 JBrowse link
G TNFSF11 TNF superfamily member 11 involved_in ISO
IEA
RGD
Ensembl
PMID:11092398 GO_REF:0000107 RGD:730134 NCBI chr 3:20,717,884...20,761,520
Ensembl chr 3:20,727,592...20,760,408
JBrowse link
regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALCR calcitonin receptor NOT|acts_upstream_of_or_within ISO (PMID:14970190) MGI PMID:14970190 NCBI chr21:55,433,438...55,585,608
Ensembl chr21:55,523,412...55,583,735
JBrowse link
G CSF1R colony stimulating factor 1 receptor involved_in ISO PMID:17121910 UniProt PMID:17121910 RGD:2293713 NCBI chr23:52,663,290...52,723,652
Ensembl chr23:52,664,076...52,697,304
JBrowse link
G IL20RA interleukin 20 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:21844205) MGI PMID:21844205 NCBI chr13:36,351,873...36,397,300
Ensembl chr13:36,352,018...36,397,302
JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within ISO (PMID:17053831) MGI PMID:17053831 NCBI chr16:24,550,983...24,836,311
Ensembl chr16:24,550,977...24,836,307
JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:53,445,607...53,458,729
Ensembl chr21:53,445,457...53,460,776
JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:32,109,436...32,117,015
Ensembl chr20:32,110,819...32,111,967
JBrowse link
G SIGLEC15 sialic acid binding Ig like lectin 15 acts_upstream_of_or_within ISO (PMID:22451653) MGI PMID:22451653 NCBI chr18:35,070,459...35,087,525 JBrowse link
G SLC4A2 solute carrier family 4 member 2 involved_in ISO (MGI:5469753|PMID:23341620) UniProt PMID:23341620 MGI:5469753 NCBI chr21:119,240,352...119,258,920
Ensembl chr21:119,241,490...119,263,193
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16522
    multicellular organismal process 7191
      tissue remodeling 220
        regulation of tissue remodeling 89
          regulation of bone remodeling 66
            negative regulation of bone remodeling + 22
            positive regulation of bone remodeling 0
            regulation of bone resorption + 54
Path 2
Term Annotations click to browse term
  biological_process 16522
    biological regulation 11317
      regulation of biological process 10983
        regulation of multicellular organismal process 3135
          regulation of tissue remodeling 89
            regulation of bone remodeling 66
              negative regulation of bone remodeling + 22
              positive regulation of bone remodeling 0
              regulation of bone resorption + 54
paths to the root