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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of bone remodeling
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Accession:GO:0046850 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.
Synonyms:exact_synonym: regulation of bone remodelling
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa;   NCBITaxon:7742 ! Vertebrata



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regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARTPT CART prepropeptide involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15724149) Ensembl
MGI
PMID:15724149 GO_REF:0000107 NCBI chr 2:54,865,043...54,867,410
Ensembl chr 2:54,865,298...54,867,158
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896
JBrowse link
G GJA1 gap junction protein alpha 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21346198) Ensembl
MGI
PMID:21346198 GO_REF:0000107 NCBI chr 1:60,941,772...60,944,694
Ensembl chr 1:60,929,097...60,942,936
JBrowse link
G INPP4B inositol polyphosphate-4-phosphatase type II B acts_upstream_of_or_within ISO (PMID:21982707) MGI PMID:21982707 NCBI chr19:826,711...1,192,340
Ensembl chr19:850,784...1,186,498
JBrowse link
G LEP leptin involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395
JBrowse link
G LEPR leptin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:44,684,118...44,775,626
Ensembl chr 5:44,688,109...44,775,636
JBrowse link
G LOC491316 midkine involved_in ISO (MGI:5008226|PMID:21185956) UniProt PMID:21185956 MGI:5008226 NCBI chr 9:55,100,491...55,101,081 JBrowse link
G MEPE matrix extracellular phosphoglycoprotein ISO RGD PMID:10967096 RGD:70633 NCBI chr32:11,212,531...11,222,805
Ensembl chr32:11,212,531...11,222,805
JBrowse link
G SUCO SUN domain containing ossification factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:26,375,414...26,410,001
Ensembl chr 7:26,376,990...26,464,125
JBrowse link
G SYT7 synaptotagmin 7 involved_in ISO (MGI:3798323|PMID:18539119) UniProt PMID:18539119 MGI:3798323 NCBI chr18:54,863,072...54,926,121
Ensembl chr18:54,861,754...54,921,367
JBrowse link
negative regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418
JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:24,262,451...24,306,162
Ensembl chr16:24,261,946...24,302,964
JBrowse link
negative regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARTPT CART prepropeptide involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:54,865,043...54,867,410
Ensembl chr 2:54,865,298...54,867,158
JBrowse link
G CD38 CD38 molecule ISO RGD PMID:10477767 RGD:2307268 NCBI chr 3:64,529,129...64,577,755
Ensembl chr 3:64,529,721...64,578,099
JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:25490771) MGI PMID:25490771 NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830
JBrowse link
G CLDN18 claudin 18 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22437732) Ensembl
MGI
PMID:22437732 GO_REF:0000107 NCBI chr23:34,229,115...34,257,431
Ensembl chr23:34,228,992...34,255,650
JBrowse link
G CRSP-3 calcitonin receptor-stimulating peptide 3 involved_in ISO (PMID:10822112), (PMID:17241109) UniProt PMID:10822112 PMID:17241109 NCBI chr21:37,676,841...37,680,643
Ensembl chr21:37,676,841...37,680,645
JBrowse link
G CSK C-terminal Src kinase ISO RGD PMID:10411542 RGD:5134371 NCBI chr30:37,851,269...37,870,382
Ensembl chr30:37,852,046...37,870,378
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 ISO RGD PMID:8694895 RGD:7257714 NCBI chr30:16,954,020...17,056,728
Ensembl chr30:16,957,215...16,988,353
JBrowse link
G FSHR follicle stimulating hormone receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11089565), (PMID:17332067) Ensembl
MGI
PMID:11089565 PMID:17332067 GO_REF:0000107 NCBI chr10:50,765,591...50,938,643
Ensembl chr10:50,770,995...50,938,474
JBrowse link
G GPR137 G protein-coupled receptor 137 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:52,776,857...52,781,050
Ensembl chr18:52,776,858...52,779,783
JBrowse link
G GPR137B G protein-coupled receptor 137B involved_in ISO (MGI:6362357|PMID:31173907) UniProt PMID:31173907 MGI:6362357 NCBI chr 4:3,819,338...3,864,690
Ensembl chr 4:3,825,602...3,864,780
JBrowse link
G HAMP hepcidin antimicrobial peptide involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24561287) Ensembl
MGI
PMID:24561287 GO_REF:0000107 NCBI chr 1:117,305,531...117,306,587
Ensembl chr 1:117,305,411...117,306,619
JBrowse link
G IAPP islet amyloid polypeptide acts_upstream_of_or_within ISO (PMID:14970190) MGI PMID:14970190 NCBI chr27:26,295,481...26,299,967
Ensembl chr27:26,295,481...26,299,967
JBrowse link
G IL6 interleukin 6 involved_in ISO (MGI:5795829|PMID:11159963) BHF-UCL PMID:11159963 MGI:5795829 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519
JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12161749) Ensembl
MGI
PMID:12161749 GO_REF:0000107 NCBI chr25:44,612,146...44,731,347
Ensembl chr25:44,611,523...44,730,200
JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12677010) Ensembl
MGI
PMID:12677010 GO_REF:0000107 NCBI chr26:7,928,863...7,983,956
Ensembl chr26:7,940,985...7,983,740
JBrowse link
G TMEM119 transmembrane protein 119 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:18,275,719...18,282,905
Ensembl chr26:18,260,923...18,282,409
JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b ISO RGD PMID:11839361 PMID:16912914 RGD:1624170 RGD:730196 NCBI chr13:18,155,765...18,183,263
Ensembl chr13:18,156,367...18,183,444
JBrowse link
G UBASH3B ubiquitin associated and SH3 domain containing B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23149425) Ensembl
TreeGrafter
MGI
PMID:23149425 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:11,496,254...11,614,769
Ensembl chr 5:11,500,669...11,614,675
JBrowse link
G VEGFA vascular endothelial growth factor A ISO RGD PMID:15312247 RGD:1580559 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965
JBrowse link
positive regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM8 ADAM metallopeptidase domain 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:40,853,665...40,865,604
Ensembl chr28:40,855,509...40,863,747
JBrowse link
G AHSG alpha 2-HS glycoprotein ISO RGD PMID:10500999 RGD:1625797 NCBI chr34:19,221,034...19,228,866
Ensembl chr34:19,221,107...19,228,716
JBrowse link
G CA2 carbonic anhydrase 2 ISO RGD PMID:8674544 RGD:1600722 NCBI chr29:31,959,225...31,975,309
Ensembl chr29:31,935,172...31,980,579
JBrowse link
G DCSTAMP dendrocyte expressed seven transmembrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:5,542,474...5,559,433
Ensembl chr13:5,542,425...5,571,968
JBrowse link
G DEF8 differentially expressed in FDCP 8 homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:63,656,411...63,671,934
Ensembl chr 5:63,656,218...63,669,025
JBrowse link
G DLK1 delta like non-canonical Notch ligand 1 acts_upstream_of_or_within ISO (PMID:21308776) MGI PMID:21308776 NCBI chr 8:68,961,975...68,970,106
Ensembl chr 8:68,961,744...68,972,761
JBrowse link
G EGFR epidermal growth factor receptor ISO RGD PMID:2981075 RGD:10395245 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631
JBrowse link
G FSHB follicle stimulating hormone subunit beta acts_upstream_of_or_within ISO (PMID:16630814) MGI PMID:16630814 NCBI chr21:50,279,320...50,282,843
Ensembl chr21:50,280,208...50,282,680
JBrowse link
G IDUA alpha-L-iduronidase acts_upstream_of_or_within ISO (PMID:19834056) MGI PMID:19834056 NCBI chr 3:91,517,225...91,534,593
Ensembl chr 3:91,522,035...91,534,593
JBrowse link
G ITGB3 integrin subunit beta 3 ISO RGD PMID:8603604 RGD:5024929 NCBI chr 9:9,179,667...9,231,061
Ensembl chr 9:9,182,562...9,231,451
JBrowse link
G LOC477072 serotransferrin involved_in ISO (MGI:3838421|PMID:19252502) DFLAT PMID:19252502 MGI:3838421 NCBI chr23:30,658,250...30,683,816
Ensembl chr23:30,595,704...30,683,845
JBrowse link
G LOC478984 low affinity immunoglobulin gamma Fc region receptor III involved_in ISO (MGI:5641770|PMID:25824719) UniProt PMID:25824719 MGI:5641770 NCBI chr38:21,054,870...21,060,948 JBrowse link
G LRP6 LDL receptor related protein 6 acts_upstream_of_or_within ISO (PMID:18505367) MGI PMID:18505367 NCBI chr27:34,003,334...34,166,334
Ensembl chr27:34,003,539...34,161,437
JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15878314) Ensembl
MGI
PMID:15878314 GO_REF:0000107 NCBI chr18:51,653,783...51,667,793
Ensembl chr18:51,659,098...51,667,433
JBrowse link
G MC4R melanocortin 4 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:16,131,829...16,132,827
Ensembl chr 1:16,131,589...16,133,079
JBrowse link
G OSCAR osteoclast associated Ig-like receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11805147) Ensembl
MGI
PMID:11805147 GO_REF:0000107 NCBI chr 1:103,101,462...103,113,593
Ensembl chr 1:103,101,819...103,106,974
JBrowse link
G PLEKHM1 pleckstrin homology and RUN domain containing M1 involved_in IEA Ensembl GO_REF:0000107
G PPARGC1B PPARG coactivator 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:59,167,041...59,278,977
Ensembl chr 4:59,174,604...59,279,464
JBrowse link
G PRKCA protein kinase C alpha involved_in ISO (MGI:5284791|PMID:16014375) BHF-UCL PMID:16014375 MGI:5284791 NCBI chr 9:13,638,106...13,879,571
Ensembl chr 9:13,644,010...13,967,630
JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:11792579 RGD:729815 NCBI chr 4:68,663,362...68,676,241
Ensembl chr 4:68,663,364...68,676,358
JBrowse link
G SPP1 secreted phosphoprotein 1 ISO RGD PMID:11792563 RGD:1581129 NCBI chr32:11,354,070...11,362,325
Ensembl chr32:11,353,953...11,362,069
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:8514886 RGD:150524326 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077
JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583
JBrowse link
G TFRC transferrin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:29,206,024...29,237,221
Ensembl chr33:29,208,609...29,238,242
JBrowse link
G TMEM64 transmembrane protein 64 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23395171) Ensembl
MGI
TreeGrafter
PMID:23395171 GO_REF:0000107 GO_REF:0000118 NCBI chr29:36,005,600...36,030,366
Ensembl chr29:35,870,805...36,030,375
JBrowse link
G TNFRSF11A TNF receptor superfamily member 11a involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11805147) Ensembl
MGI
PMID:11805147 GO_REF:0000107 NCBI chr 1:14,504,595...14,555,956
Ensembl chr 1:14,503,033...14,556,041
JBrowse link
G TNFSF11 TNF superfamily member 11 involved_in ISO
IEA
RGD
Ensembl
PMID:11092398 GO_REF:0000107 RGD:730134 NCBI chr22:8,226,931...8,257,926
Ensembl chr22:8,227,555...8,258,645
JBrowse link
regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALCR calcitonin receptor NOT|acts_upstream_of_or_within ISO (PMID:14970190) MGI PMID:14970190 NCBI chr14:18,923,116...19,074,904
Ensembl chr14:18,923,116...19,074,904
JBrowse link
G CSF1R colony stimulating factor 1 receptor involved_in ISO PMID:17121910 UniProt PMID:17121910 RGD:2293713 NCBI chr 4:58,980,699...59,010,683
Ensembl chr 4:58,980,788...59,010,510
JBrowse link
G IL20RA interleukin 20 receptor subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21844205) Ensembl
MGI
PMID:21844205 GO_REF:0000107 NCBI chr 1:29,506,582...29,545,882
Ensembl chr 1:29,506,689...29,546,006
JBrowse link
G NF1 neurofibromin 1 acts_upstream_of_or_within ISO (PMID:17053831) MGI PMID:17053831 NCBI chr 9:41,467,460...41,679,388
Ensembl chr 9:41,469,416...41,679,382
JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:20,825,861...20,839,290
Ensembl chr14:20,827,831...20,839,256
JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 involved_in ISO (MGI:3839226|PMID:19204730) UniProt PMID:19204730 MGI:3839226 NCBI chr 6:48,897,320...48,902,206
Ensembl chr 6:48,897,449...48,900,037
JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 involved_in IEA Ensembl GO_REF:0000107
G SIGLEC15 sialic acid binding Ig like lectin 15 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:22451653) Ensembl
MGI
PMID:22451653 GO_REF:0000107 NCBI chr 7:45,322,677...45,338,103
Ensembl chr 7:45,324,440...45,337,814
JBrowse link
G SLC4A2 solute carrier family 4 member 2 involved_in ISO (MGI:5469753|PMID:23341620) UniProt PMID:23341620 MGI:5469753 NCBI chr16:15,111,078...15,126,618
Ensembl chr16:15,111,116...15,126,617
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17307
    multicellular organismal process 7953
      tissue remodeling 228
        regulation of tissue remodeling 89
          regulation of bone remodeling 66
            negative regulation of bone remodeling + 21
            positive regulation of bone remodeling 0
            regulation of bone resorption + 55
Path 2
Term Annotations click to browse term
  biological_process 17307
    biological regulation 12009
      regulation of biological process 11678
        regulation of multicellular organismal process 3264
          regulation of tissue remodeling 89
            regulation of bone remodeling 66
              negative regulation of bone remodeling + 21
              positive regulation of bone remodeling 0
              regulation of bone resorption + 55
paths to the root