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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of bone remodeling
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Accession:GO:0046850 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.
Synonyms:exact_synonym: regulation of bone remodelling
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa;   NCBITaxon:7742 ! Vertebrata


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regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cartpt CART prepropeptide acts_upstream_of_or_within ISO (PMID:15724149) MGI PMID:15724149 NCBI chrNW_004955575:551,991...555,118
Ensembl chrNW_004955575:551,991...555,149
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chrNW_004955514:1,030,244...1,038,590
Ensembl chrNW_004955514:1,025,600...1,038,590
JBrowse link
G Gja1 gap junction protein alpha 1 acts_upstream_of_or_within ISO (PMID:21346198) MGI PMID:21346198 NCBI chrNW_004955436:3,612,533...3,618,095
Ensembl chrNW_004955436:3,612,533...3,618,095
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B acts_upstream_of_or_within ISO (PMID:21982707) MGI PMID:21982707 NCBI chrNW_004955471:938,005...1,291,695
Ensembl chrNW_004955471:938,005...1,291,695
JBrowse link
G Lep leptin involved_in ISO (MGI:1352383|PMID:10660043) UniProt PMID:10660043 MGI:1352383 NCBI chrNW_004955479:9,266,604...9,276,568
Ensembl chrNW_004955479:9,274,516...9,279,472
JBrowse link
G Lepr leptin receptor involved_in ISO (MGI:1352383|PMID:10660043) UniProt PMID:10660043 MGI:1352383 NCBI chrNW_004955423:25,108,897...25,185,315
Ensembl chrNW_004955423:25,111,266...25,185,407
JBrowse link
G Mdk midkine involved_in ISO (MGI:5008226|PMID:21185956) UniProt PMID:21185956 MGI:5008226 NCBI chrNW_004955422:1,655,351...1,657,026
Ensembl chrNW_004955422:1,655,358...1,657,044
JBrowse link
G Mepe matrix extracellular phosphoglycoprotein ISO RGD PMID:10967096 RGD:70633 NCBI chrNW_004955474:2,048,883...2,064,515 JBrowse link
G Suco SUN domain containing ossification factor involved_in ISO (MGI:4452525|PMID:20440000) UniProt PMID:20440000 MGI:4452525 NCBI chrNW_004955406:12,985,339...13,064,863
Ensembl chrNW_004955406:12,985,856...13,065,855
JBrowse link
G Syt7 synaptotagmin 7 involved_in ISO (MGI:3798323|PMID:18539119) UniProt PMID:18539119 MGI:3798323 NCBI chrNW_004955511:6,051,392...6,093,651
Ensembl chrNW_004955511:6,051,386...6,093,651
JBrowse link
negative regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chrNW_004955416:1,812,725...1,825,528
Ensembl chrNW_004955416:1,812,676...1,826,271
JBrowse link
G Sfrp1 secreted frizzled related protein 1 involved_in ISO (PMID:19072540) UniProt PMID:19072540 NCBI chrNW_004955536:1,663,721...1,702,678
Ensembl chrNW_004955536:1,663,344...1,703,514
JBrowse link
negative regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cartpt CART prepropeptide involved_in ISO (PMID:16614075)
(MGI:3696590|PMID:16614075)
HGNC-UCL PMID:16614075 MGI:3696590 NCBI chrNW_004955575:551,991...555,118
Ensembl chrNW_004955575:551,991...555,149
JBrowse link
G Cd38 CD38 molecule ISO RGD PMID:10477767 RGD:2307268 NCBI chrNW_004955480:8,177,178...8,218,483
Ensembl chrNW_004955480:8,178,473...8,217,643
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:25490771) MGI PMID:25490771 NCBI chrNW_004955555:426,894...446,235 JBrowse link
G Cldn18 claudin 18 acts_upstream_of_or_within ISO (PMID:22437732) MGI PMID:22437732 NCBI chrNW_004955501:962,188...991,922
Ensembl chrNW_004955501:962,188...991,922
JBrowse link
G Csk C-terminal Src kinase ISO RGD PMID:10411542 RGD:5134371 NCBI chrNW_004955450:3,127,561...3,144,550
Ensembl chrNW_004955450:3,127,561...3,144,550
JBrowse link
G Fshr follicle stimulating hormone receptor acts_upstream_of_or_within ISO (PMID:11089565), (PMID:17332067) MGI PMID:11089565 PMID:17332067 NCBI chrNW_004955441:15,422,190...15,585,446
Ensembl chrNW_004955441:15,422,190...15,585,537
JBrowse link
G Gpr137b G protein-coupled receptor 137B involved_in ISO (MGI:6362357|PMID:31173907) UniProt PMID:31173907 MGI:6362357 NCBI chrNW_004955492:3,916,536...3,952,330
Ensembl chrNW_004955492:3,916,536...3,952,330
JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of_or_within ISO (PMID:24561287) MGI PMID:24561287 NCBI chrNW_004955468:4,576,080...4,577,591
Ensembl chrNW_004955468:4,575,510...4,577,649
JBrowse link
G Iapp islet amyloid polypeptide acts_upstream_of_or_within ISO (PMID:14970190) MGI PMID:14970190 NCBI chrNW_004955413:16,834,940...16,841,071
Ensembl chrNW_004955413:16,835,037...16,840,682
JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:5795829|PMID:11159963) BHF-UCL PMID:11159963 MGI:5795829 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D acts_upstream_of_or_within ISO (PMID:12161749) MGI PMID:12161749 NCBI chrNW_004955453:2,938,659...3,037,211
Ensembl chrNW_004955453:2,938,659...3,037,211
JBrowse link
G LOC102023780 aromatase ISO RGD PMID:8694895 RGD:7257714 NCBI chrNW_004955409:3,198,622...3,313,072
Ensembl chrNW_004955409:3,266,233...3,313,142
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:12677010) MGI PMID:12677010 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926
JBrowse link
G Tmem119 transmembrane protein 119 involved_in ISO (MGI:5543589|PMID:22416756) ARUK-UCL PMID:22416756 MGI:5543589 NCBI chrNW_004955455:9,856,443...9,863,100
Ensembl chrNW_004955455:9,856,443...9,863,100
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11b ISO RGD PMID:11839361 PMID:16912914 RGD:1624170 RGD:730196 NCBI chrNW_004955417:24,804,708...24,831,338
Ensembl chrNW_004955417:24,804,664...24,831,894
JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing B acts_upstream_of_or_within ISO (PMID:23149425) MGI PMID:23149425 NCBI chrNW_004955412:23,518,851...23,667,617
Ensembl chrNW_004955412:23,518,240...23,667,697
JBrowse link
G Vegfa vascular endothelial growth factor A ISO RGD PMID:15312247 RGD:1580559 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
positive regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 ADAM metallopeptidase domain 8 involved_in ISO (MGI:5009189|PMID:11341326)
(MGI:5009349|PMID:20683884)
BHF-UCL PMID:11341326 PMID:20683884 MGI:5009189 MGI:5009349 NCBI chrNW_004955477:10,894,288...10,906,961
Ensembl chrNW_004955477:10,895,446...10,907,215
JBrowse link
G Ahsg alpha 2-HS glycoprotein ISO RGD PMID:10500999 RGD:1625797 NCBI chrNW_004955420:21,071,111...21,078,397
Ensembl chrNW_004955420:21,069,681...21,078,298
JBrowse link
G Ca2 carbonic anhydrase 2 ISO RGD PMID:8674544 RGD:1600722 NCBI chrNW_004955417:3,388,110...3,402,798
Ensembl chrNW_004955417:3,386,087...3,402,363
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein involved_in ISO (MGI:3588832|PMID:16061724), (MGI:5426134|PMID:17164993), (MGI:5426135|PMID:16937266) UniProt PMID:16061724 PMID:16937266 PMID:17164993 MGI:3588832 MGI:5426134 MGI:5426135 NCBI chrNW_004955417:28,156,046...28,169,481
Ensembl chrNW_004955417:28,155,842...28,168,049
JBrowse link
G Def8 differentially expressed in FDCP 8 homolog involved_in ISO (MGI:5806241|PMID:27777970) UniProt PMID:27777970 MGI:5806241 NCBI chrNW_004955541:3,412,534...3,424,010
Ensembl chrNW_004955541:3,412,484...3,424,869
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 acts_upstream_of_or_within ISO (PMID:21308776) MGI PMID:21308776 NCBI chrNW_004955627:37,886...43,730
Ensembl chrNW_004955627:38,128...43,728
JBrowse link
G Egfr epidermal growth factor receptor ISO RGD PMID:2981075 RGD:10395245 NCBI chrNW_004955456:321,222...456,431 JBrowse link
G Fshb follicle stimulating hormone subunit beta acts_upstream_of_or_within ISO (PMID:16630814) MGI PMID:16630814 NCBI chrNW_004955476:8,795,354...8,797,244
Ensembl chrNW_004955476:8,795,351...8,797,244
JBrowse link
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO (PMID:19834056) MGI PMID:19834056 NCBI chrNW_004955514:474,830...488,007
Ensembl chrNW_004955514:475,731...488,007
JBrowse link
G Itgb3 integrin subunit beta 3 ISO RGD PMID:8603604 RGD:5024929 NCBI chrNW_004955478:9,788,192...9,830,254
Ensembl chrNW_004955478:9,788,149...9,823,746
JBrowse link
G LOC102027549 serotransferrin involved_in ISO (MGI:3838421|PMID:19252502) DFLAT PMID:19252502 MGI:3838421 NCBI chrNW_004955501:4,801,710...4,832,025
Ensembl chrNW_004955501:4,801,885...4,831,910
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO (PMID:18505367) MGI PMID:18505367 NCBI chrNW_004955413:9,080,901...9,237,644
Ensembl chrNW_004955413:9,080,914...9,237,650
JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within ISO (PMID:15878314) MGI PMID:15878314 NCBI chrNW_004955422:19,714,161...19,730,344
Ensembl chrNW_004955422:19,714,627...19,729,855
JBrowse link
G Mc4r melanocortin 4 receptor involved_in ISO (PMID:16614075)
(MGI:3696590|PMID:16614075)
HGNC-UCL PMID:16614075 MGI:3696590 NCBI chrNW_004955402:44,453,973...44,456,689
Ensembl chrNW_004955402:44,455,294...44,456,292
JBrowse link
G Plekhm1 pleckstrin homology and RUN domain containing M1 involved_in ISO (MGI:5806241|PMID:27777970) UniProt PMID:27777970 MGI:5806241 NCBI chrNW_004955451:18,043,194...18,079,808
Ensembl chrNW_004955451:18,043,194...18,079,873
JBrowse link
G Ppargc1b PPARG coactivator 1 beta involved_in ISO (MGI:3838421|PMID:19252502) DFLAT PMID:19252502 MGI:3838421 NCBI chrNW_004955415:4,638,057...4,756,885
Ensembl chrNW_004955415:4,644,998...4,757,093
JBrowse link
G Prkca protein kinase C alpha involved_in ISO (MGI:5284791|PMID:16014375) BHF-UCL PMID:16014375 MGI:5284791 NCBI chrNW_004955478:5,686,639...6,090,356
Ensembl chrNW_004955478:5,686,640...6,083,967
JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:11792579 RGD:729815 NCBI chrNW_004955426:24,997,811...25,010,822
Ensembl chrNW_004955426:24,997,811...25,010,822
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:11792563 RGD:1581129 NCBI chrNW_004955474:1,914,477...1,922,025
Ensembl chrNW_004955474:1,913,829...1,922,016
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:8514886 RGD:150524326 NCBI chrNW_004955445:19,213,210...19,227,670
Ensembl chrNW_004955445:19,215,161...19,228,695
JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO (MGI:3703840|PMID:17353363) UniProt PMID:17353363 MGI:3703840 NCBI chrNW_004955515:1,328,793...1,400,206
Ensembl chrNW_004955515:1,328,630...1,380,581
JBrowse link
G Tfrc transferrin receptor involved_in ISO (MGI:3838421|PMID:19252502) DFLAT PMID:19252502 MGI:3838421 NCBI chrNW_004955420:12,348,392...12,372,714
Ensembl chrNW_004955420:12,348,821...12,372,691
JBrowse link
G Tmem64 transmembrane protein 64 acts_upstream_of_or_within ISO (PMID:23395171) MGI PMID:23395171 NCBI chrNW_004955417:7,436,690...7,483,190 JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11a acts_upstream_of_or_within ISO (PMID:11805147) MGI PMID:11805147 NCBI chrNW_004955402:46,242,329...46,298,157
Ensembl chrNW_004955402:46,264,164...46,296,368
JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in ISO (PMID:17241109) RGD
UniProt
PMID:11092398 PMID:17241109 RGD:730134 NCBI chrNW_004955518:431,401...462,063
Ensembl chrNW_004955518:430,642...462,705
JBrowse link
regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calcr calcitonin receptor NOT|acts_upstream_of_or_within ISO (PMID:14970190) MGI PMID:14970190 NCBI chrNW_004955432:10,310,776...10,391,029
Ensembl chrNW_004955432:10,309,263...10,391,141
JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in ISO PMID:17121910 UniProt PMID:17121910 RGD:2293713 NCBI chrNW_004955415:4,434,486...4,462,505
Ensembl chrNW_004955415:4,434,453...4,461,751
JBrowse link
G Il20ra interleukin 20 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:21844205) MGI PMID:21844205 NCBI chrNW_004955436:22,281,422...22,323,242
Ensembl chrNW_004955436:22,281,713...22,326,229
JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of_or_within ISO (PMID:17053831) MGI PMID:17053831 NCBI chrNW_004955481:6,145,855...6,404,179
Ensembl chrNW_004955481:6,145,855...6,404,179
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 involved_in ISO (MGI:5303050|PMID:21803180) UniProt PMID:21803180 MGI:5303050 NCBI chrNW_004955432:12,169,548...12,182,064
Ensembl chrNW_004955432:12,169,435...12,182,409
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 involved_in ISO (MGI:3839226|PMID:19204730) UniProt PMID:19204730 MGI:3839226 NCBI chrNW_004955435:5,880,266...5,882,823
Ensembl chrNW_004955435:5,880,288...5,881,436
JBrowse link
G Siglec15 sialic acid binding Ig like lectin 15 acts_upstream_of_or_within ISO (PMID:22451653) MGI PMID:22451653 NCBI chrNW_004955402:31,403,765...31,418,954
Ensembl chrNW_004955402:31,403,965...31,417,386
JBrowse link
G Slc4a2 solute carrier family 4 member 2 involved_in ISO (MGI:5469753|PMID:23341620) UniProt PMID:23341620 MGI:5469753 NCBI chrNW_004955491:5,498,472...5,513,389
Ensembl chrNW_004955491:5,499,033...5,517,319
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12382
    multicellular organismal process 6207
      tissue remodeling 206
        regulation of tissue remodeling 84
          regulation of bone remodeling 61
            negative regulation of bone remodeling + 19
            positive regulation of bone remodeling 0
            regulation of bone resorption + 50
Path 2
Term Annotations click to browse term
  biological_process 12382
    biological regulation 8910
      regulation of biological process 8643
        regulation of multicellular organismal process 2860
          regulation of tissue remodeling 84
            regulation of bone remodeling 61
              negative regulation of bone remodeling + 19
              positive regulation of bone remodeling 0
              regulation of bone resorption + 50
paths to the root