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ONTOLOGY REPORT - ANNOTATIONS


Term:bone remodeling
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Accession:GO:0046849 term browser browse the term
Definition:The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis.
Synonyms:exact_synonym: bone remodelling
 xref: Wikipedia:Bone_remodeling



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bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc154 coiled-coil domain containing 154 acts_upstream_of_or_within ISO (PMID:33614666) RGD PMID:33614666 NCBI chr10:14,177,271...14,187,378
Ensembl chr10:14,177,278...14,187,253
JBrowse link
G Ctnnb1 catenin beta 1 IEP RGD PMID:29224185 RGD:13792728 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Dock5 dedicator of cytokinesis 5 acts_upstream_of_or_within ISO (PMID:27505886) RGD PMID:27505886 NCBI chr15:41,979,728...42,158,733
Ensembl chr15:41,979,729...42,158,649
JBrowse link
G Efna2 ephrin A2 involved_in ISO
IBA
(MGI:5284751|PMID:19299512)
GO_REF:0000033
RGD
GO_Central
PMID:19299512 GO_REF:0000033 MGI:5284751 NCBI chr 7:9,515,635...9,528,071
Ensembl chr 7:9,516,429...9,527,061
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in
acts_upstream_of_or_within
ISO MGI:1857079 (PMID:9541520)
MGI:1857079 (PMID:10024383)
RGD PMID:9541520 PMID:10024383 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (MGI:5284751|PMID:19299512) RGD PMID:19299512 MGI:5284751 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Gja1 gap junction protein, alpha 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:6274948|PMID:25270829)
UniProt
RGD
PMID:25270829 GO_REF:0000024 MGI:6274948 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IDA RGD PMID:29224185 RGD:13792728 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B acts_upstream_of_or_within ISO MGI:1278315|MGI:98796 (PMID:19041748) RGD PMID:19041748 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549
JBrowse link
G Il6 interleukin 6 IEP RGD PMID:16193234 RGD:1601024 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 involved_in ISS
ISO
GO_REF:0000024
(MGI:4360132|PMID:19605502)
UniProt
RGD
PMID:19605502 GO_REF:0000024 MGI:4360132 NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899
JBrowse link
G Lrp5 LDL receptor related protein 5 acts_upstream_of_or_within ISO MGI:1298218|MGI:2183279|MGI:3530598|MGI:3612485|MGI:96274|MGI:98796 (PMID:11956231), (PMID:12817748), (PMID:15207752), (PMID:15537447), (PMID:16790443), (PMID:17147489), (PMID:17627087), (PMID:19041748) RGD PMID:11956231 PMID:12817748 PMID:15207752 PMID:15537447 PMID:16790443 More... NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:1278315 (PMID:15537447) RGD PMID:15537447 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within ISO MGI:2180017 (PMID:11790802) RGD PMID:11790802 NCBI chr 1:203,029,412...203,045,975
Ensembl chr 1:203,029,877...203,045,975
JBrowse link
G Lypd8l1 LY6/PLAUR domain containing 8 like 1 involved_in IEP PMID:9461570 UniProt PMID:9461570 RGD:1299027 NCBI chr10:42,615,555...42,623,925
Ensembl chr10:42,615,555...42,623,784
JBrowse link
G Mitf melanocyte inducing transcription factor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856095 (PMID:12086670)
Ensembl
RGD
PMID:12086670 GO_REF:0000107 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
JBrowse link
G Notch2 notch receptor 2 involved_in ISO
IEA
(PMID:21378985), (PMID:21378989)
GO_REF:0000107
RGD
Ensembl
PMID:21378985 PMID:21378989 GO_REF:0000107 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
JBrowse link
G P3h4 prolyl 3-hydroxylase family member 4 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5779580|PMID:27119146), (MGI:5897747|PMID:23959653)
UniProt
Ensembl
RGD
PMID:23959653 PMID:27119146 GO_REF:0000024 GO_REF:0000107 MGI:5779580 MGI:5897747 NCBI chr10:85,338,158...85,345,108
Ensembl chr10:85,338,161...85,345,093
JBrowse link
G Ptprv protein tyrosine phosphatase, receptor type, V IEP RGD PMID:7527035 RGD:632779 NCBI chr13:46,548,125...46,569,148
Ensembl chr13:46,548,128...46,568,329
JBrowse link
G Rassf2 Ras association domain family member 2 acts_upstream_of_or_within ISO MGI:5314787 (PMID:22227519) RGD PMID:22227519 NCBI chr 3:119,244,288...119,280,462
Ensembl chr 3:119,245,821...119,280,431
JBrowse link
G Slc34a1 solute carrier family 34 member 1 acts_upstream_of_or_within ISO MGI:2386786 (PMID:9560283) RGD PMID:9560283 NCBI chr17:9,218,876...9,233,852
Ensembl chr17:9,218,876...9,233,852
JBrowse link
G Snx10 sorting nexin 10 acts_upstream_of_or_within ISO MGI:5690193 (PMID:25811986) RGD PMID:25811986 NCBI chr 4:80,612,648...80,677,005
Ensembl chr 4:80,612,669...80,676,996
JBrowse link
G Spp2 secreted phosphoprotein 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:89,006,858...89,026,676
Ensembl chr 9:89,007,175...89,026,688
JBrowse link
G Tph1 tryptophan hydroxylase 1 acts_upstream_of_or_within ISO MGI:1278315|MGI:96274 (PMID:19041748) RGD PMID:19041748 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344
JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (MGI:2181820|PMID:10421844) RGD PMID:10421844 MGI:2181820 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Wnt16 Wnt family member 16 acts_upstream_of_or_within ISO MGI:5467557 (PMID:22792071) RGD PMID:22792071 NCBI chr 4:50,820,968...50,831,380
Ensembl chr 4:50,820,968...50,831,380
JBrowse link
bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant involved_in
acts_upstream_of_or_within
TAS
IEP
IEA
IBA
ISO
GO_REF:0000107
GO_REF:0000033
MGI:2180086 (PMID:8898228)
Ensembl
GO_Central
RGD
PMID:8898228 PMID:1722212 PMID:20069278 GO_REF:0000033 GO_REF:0000107, RGD:1298628, RGD:2315871 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
JBrowse link
G Adrb2 adrenoceptor beta 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1859675 (PMID:15724149)
Ensembl
RGD
PMID:15724149 GO_REF:0000107 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Ccdc154 coiled-coil domain containing 154 acts_upstream_of_or_within ISO MGI:5702426 (PMID:20121924) RGD PMID:20121924 NCBI chr10:14,177,271...14,187,378
Ensembl chr10:14,177,278...14,187,253
JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1858008|MGI:2148567|MGI:3041864|MGI:98504 (PMID:15866165)
Ensembl
RGD
PMID:15866165 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsk cathepsin K acts_upstream_of_or_within IMP
ISO
MGI:2182131 (PMID:19834056) RGD PMID:19834056 PMID:10430032 RGD:1601030 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
JBrowse link
G Ctss cathepsin S IMP RGD PMID:10470376 RGD:5687153 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:1857079 (PMID:28798354) RGD PMID:28798354 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (PMID:29415886) RGD PMID:29415886 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
G Gpr55 G protein-coupled receptor 55 involved_in ISO (PMID:19805329) RGD PMID:19805329 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613
JBrowse link
G Hnf1a HNF1 homeobox A acts_upstream_of_or_within ISO MGI:88276 (PMID:15866165) RGD PMID:15866165 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Iapp islet amyloid polypeptide acts_upstream_of ISO MGI:2656235 (PMID:14970190) RGD PMID:14970190 NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920
JBrowse link
G Ihh Indian hedgehog signaling molecule acts_upstream_of_or_within ISO (PMID:10208865) RGD PMID:10208865 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Il7 interleukin 7 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
GO_REF:0000024
(PMID:12490655)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12490655 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Lrrk1 leucine-rich repeat kinase 1 acts_upstream_of_or_within ISO MGI:5568128 (PMID:23526378) RGD PMID:23526378 NCBI chr 1:119,844,360...119,972,885
Ensembl chr 1:119,845,146...119,979,734
JBrowse link
G Mir34a microRNA 34a acts_upstream_of_or_within_negative_effect ISO (PMID:25043055) RGD PMID:25043055 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
JBrowse link
G Ncdn neurochondrin acts_upstream_of_or_within ISO (PMID:10231559) RGD PMID:10231559 NCBI chr 5:139,037,807...139,047,645
Ensembl chr 5:139,037,819...139,047,568
JBrowse link
G Nox4 NADPH oxidase 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:11098048)
Ensembl
RGD
PMID:11098048 GO_REF:0000107 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Pth parathyroid hormone TAS RGD PMID:11145578 RGD:61525 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530
JBrowse link
G Pth1r parathyroid hormone 1 receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2154519 (PMID:9832460)
Ensembl
RGD
PMID:9832460 GO_REF:0000107 NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISS
ISO
GO_REF:0000024
(MGI:3040548|PMID:14739300)
UniProt
RGD
PMID:14739300 GO_REF:0000024 MGI:3040548 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Rab3d RAB3D, member RAS oncogene family involved_in ISO (PMID:21262767) RGD PMID:21262767 NCBI chr 8:20,438,622...20,449,269
Ensembl chr 8:20,439,294...20,449,185
JBrowse link
G Rab7a RAB7A, member RAS oncogene family IMP RGD PMID:11514537 RGD:729760 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889
JBrowse link
G Rac1 Rac family small GTPase 1 IDA RGD PMID:10350213 RGD:1599401 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rac2 Rac family small GTPase 2 IDA RGD PMID:10350213 RGD:1599401 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720
JBrowse link
G Snx10 sorting nexin 10 acts_upstream_of_or_within ISO MGI:5690193 (PMID:25811986) RGD PMID:25811986 NCBI chr 4:80,612,648...80,677,005
Ensembl chr 4:80,612,669...80,676,996
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:1857247 (PMID:19448635)
(MGI:3040548|PMID:14739300)
UniProt
RGD
PMID:14739300 PMID:19448635 GO_REF:0000024 MGI:3040548 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 acts_upstream_of_or_within ISO MGI:1856973|MGI:5496553 (PMID:18768394), (PMID:21305608), (PMID:22087326), (PMID:23166162), (PMID:23908015) RGD PMID:18768394 PMID:21305608 PMID:22087326 PMID:23166162 PMID:23908015 NCBI chr 1:201,127,034...201,138,787
Ensembl chr 1:201,127,034...201,138,742
JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:12490655)
Ensembl
RGD
PMID:12490655 GO_REF:0000107 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tns3 tensin 3 acts_upstream_of_or_within ISO (PMID:27505886) RGD PMID:27505886 NCBI chr14:83,173,649...83,405,671
Ensembl chr14:83,173,649...83,405,998
JBrowse link
G Tpp1 tripeptidyl peptidase 1 involved_in ISS
IEA
ISO
PMID:14609438
GO_REF:0000107
(PMID:8215436)
Ensembl
RGD
PMID:8215436 PMID:14609438 GO_REF:0000107, RGD:8554137 NCBI chr 1:160,097,984...160,104,108
Ensembl chr 1:160,096,833...160,104,129
JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO
IEA
(MGI:1335941|PMID:10215628)
GO_REF:0000107
RGD
Ensembl
PMID:10215628 GO_REF:0000107 MGI:1335941 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
negative regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) RGD PMID:15539560 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19072540)
Ensembl
RGD
PMID:19072540 GO_REF:0000107 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286
JBrowse link
negative regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha involved_in ISO (PMID:10822112), (PMID:17241109) RGD PMID:10822112 PMID:17241109 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Cartpt CART prepropeptide involved_in ISO (PMID:16614075)
UniProtKB:P56450 (MGI:3696590|PMID:16614075)
RGD PMID:16614075 MGI:3696590 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
JBrowse link
G Cd38 CD38 molecule IDA RGD PMID:10477767 RGD:2307268 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO MGI:5560663 (PMID:25490771) RGD PMID:25490771 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Cldn18 claudin 18 acts_upstream_of_or_within ISO MGI:5007067 (PMID:22437732) RGD PMID:22437732 NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351
JBrowse link
G Csk C-terminal Src kinase IDA RGD PMID:10411542 RGD:5134371 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IMP RGD PMID:8694895 RGD:7257714 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Fshr follicle stimulating hormone receptor acts_upstream_of_or_within ISO MGI:2384087 (PMID:11089565), (PMID:17332067) RGD PMID:11089565 PMID:17332067 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
JBrowse link
G Gpr137 G protein-coupled receptor 137 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:204,129,636...204,132,622
Ensembl chr 1:204,129,636...204,133,082
JBrowse link
G Gpr137b G protein-coupled receptor 137B involved_in ISO
IBA
(MGI:6362357|PMID:31173907)
GO_REF:0000033
RGD
GO_Central
PMID:31173907 GO_REF:0000033 MGI:6362357 NCBI chr17:86,003,635...86,041,841
Ensembl chr17:85,966,921...86,041,835
JBrowse link
G Hamp hepcidin antimicrobial peptide acts_upstream_of_or_within ISO MGI:4351741 (PMID:24561287) RGD PMID:24561287 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Iapp islet amyloid polypeptide acts_upstream_of_or_within ISO MGI:2656235 (PMID:14970190) RGD PMID:14970190 NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920
JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:5795829|PMID:11159963) RGD PMID:11159963 MGI:5795829 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:2386884 (PMID:12161749)
GO_REF:0000033
Ensembl
RGD
GO_Central
PMID:12161749 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080 (PMID:12677010) RGD PMID:12677010 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Tmem119 transmembrane protein 119 involved_in ISO (MGI:5543589|PMID:22416756) RGD PMID:22416756 MGI:5543589 NCBI chr12:42,828,621...42,835,678
Ensembl chr12:42,828,418...42,835,689
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B IMP
IDA
RGD PMID:11839361 PMID:16912914 RGD:730196, RGD:1624170 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:23149425)
GO_Central
RGD
PMID:23149425 GO_REF:0000033 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201
JBrowse link
G Vegfa vascular endothelial growth factor A IMP RGD PMID:15312247 RGD:1580559 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
ossification involved in bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cthrc1 collagen triple helix repeat containing 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3830252 (PMID:18779865)
Ensembl
RGD
PMID:18779865 GO_REF:0000107 NCBI chr 7:70,122,474...70,132,756
Ensembl chr 7:70,122,474...70,132,756
JBrowse link
G Gdf5 growth differentiation factor 5 IEP RGD PMID:10404008 RGD:2289026 NCBI chr 3:144,454,316...144,458,508
Ensembl chr 3:144,454,338...144,458,612
JBrowse link
G Ptn pleiotrophin involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19442624)
UniProt
Ensembl
RGD
PMID:19442624 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456
JBrowse link
positive regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 ADAM metallopeptidase domain 8 involved_in ISO (MGI:5009189|PMID:11341326), (MGI:5009349|PMID:20683884) RGD PMID:11341326 PMID:20683884 MGI:5009189 MGI:5009349 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
JBrowse link
G Ahsg alpha-2-HS-glycoprotein IMP RGD PMID:10500999 RGD:1625797 NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999
JBrowse link
G Car2 carbonic anhydrase 2 IMP RGD PMID:8674544 RGD:1600722 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein involved_in ISO (MGI:3588832|PMID:16061724), (MGI:5426134|PMID:17164993), (MGI:5426135|PMID:16937266) RGD PMID:16061724 PMID:16937266 PMID:17164993 MGI:3588832 MGI:5426134 MGI:5426135 NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078
JBrowse link
G Def8 differentially expressed in FDCP 8 homolog involved_in ISS
ISO
GO_REF:0000024
(MGI:5806241|PMID:27777970)
UniProt
RGD
PMID:27777970 GO_REF:0000024 MGI:5806241 NCBI chr19:51,474,783...51,495,638
Ensembl chr19:51,474,878...51,495,638
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 acts_upstream_of_or_within ISO MGI:3526402 (PMID:21308776) RGD PMID:21308776 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
JBrowse link
G Egfr epidermal growth factor receptor IMP RGD PMID:2981075 RGD:10395245 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in ISO (MGI:5641770|PMID:25824719) RGD PMID:25824719 MGI:5641770 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Fshb follicle stimulating hormone subunit beta acts_upstream_of_or_within ISO MGI:1857434 (PMID:16630814) RGD PMID:16630814 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO MGI:2176236 (PMID:19834056) RGD PMID:19834056 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522
JBrowse link
G Itgb3 integrin subunit beta 3 IMP RGD PMID:8603604 RGD:5024929 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:2673982 (PMID:18505367) RGD PMID:18505367 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within ISO MGI:2180017 (PMID:15878314) RGD PMID:15878314 NCBI chr 1:203,029,412...203,045,975
Ensembl chr 1:203,029,877...203,045,975
JBrowse link
G Mc4r melanocortin 4 receptor involved_in ISO (PMID:16614075)
(MGI:3696590|PMID:16614075)
RGD PMID:16614075 MGI:3696590 NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719
JBrowse link
G Oscar osteoclast associated Ig-like receptor acts_upstream_of_or_within ISO (PMID:11805147) RGD PMID:11805147 NCBI chr 1:65,607,214...65,615,395
Ensembl chr 1:65,607,410...65,613,758
JBrowse link
G Plekhm1 pleckstrin homology and RUN domain containing M1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5806241|PMID:27777970)
UniProt
RGD
PMID:27777970 GO_REF:0000024 MGI:5806241 NCBI chr10:88,313,837...88,366,182
Ensembl chr10:88,314,651...88,362,412
JBrowse link
G Ppargc1b PPARG coactivator 1 beta involved_in ISO
IEA
(MGI:3838421|PMID:19252502)
GO_REF:0000107
RGD
Ensembl
PMID:19252502 GO_REF:0000107 MGI:3838421 NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194
JBrowse link
G Prkca protein kinase C, alpha involved_in ISO (MGI:5284791|PMID:16014375) RGD PMID:16014375 MGI:5284791 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:11792579 RGD:729815 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
G Spp1 secreted phosphoprotein 1 involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:11792563 GO_REF:0000033, RGD:1581129 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IMP RGD PMID:8514886 RGD:150524326 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3703840|PMID:17353363)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17353363 GO_REF:0000024 GO_REF:0000107 MGI:3703840 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
G Tf transferrin involved_in ISO (MGI:3838421|PMID:19252502) RGD PMID:19252502 MGI:3838421 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tfrc transferrin receptor involved_in ISO (MGI:3838421|PMID:19252502) RGD PMID:19252502 MGI:3838421 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tmem64 transmembrane protein 64 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:3880885 (PMID:23395171)
GO_Central
RGD
PMID:23395171 GO_REF:0000033 NCBI chr 5:28,698,947...28,745,384
Ensembl chr 5:28,698,918...28,745,330
JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:11805147)
GO_Central
RGD
PMID:11805147 GO_REF:0000033 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695
JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in IMP
IEA
ISO
GO_REF:0000107
(PMID:17241109)
Ensembl
RGD
PMID:17241109 PMID:11092398 GO_REF:0000107, RGD:730134 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
JBrowse link
regulation of bone remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cartpt CART prepropeptide acts_upstream_of_or_within ISO MGI:3576858 (PMID:15724149) RGD PMID:15724149 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:2135670 (PMID:20053668) RGD PMID:20053668 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within ISO MGI:2445468|MGI:3776013 (PMID:21346198) RGD PMID:21346198 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B acts_upstream_of_or_within ISO MGI:5297505 (PMID:21982707) RGD PMID:21982707 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634
JBrowse link
G Lep leptin involved_in ISS
ISO
GO_REF:0000024
(MGI:1352383|PMID:10660043)
UniProt
RGD
PMID:10660043 GO_REF:0000024 MGI:1352383 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepr leptin receptor involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:1352383|PMID:10660043)
UniProt
Ensembl
RGD
PMID:10660043 GO_REF:0000024 GO_REF:0000107 MGI:1352383 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Mdk midkine involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5008226|PMID:21185956)
UniProt
Ensembl
RGD
PMID:21185956 GO_REF:0000024 GO_REF:0000107 MGI:5008226 NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130
JBrowse link
G Mepe matrix extracellular phosphoglycoprotein IEP RGD PMID:10967096 RGD:70633 NCBI chr14:5,420,634...5,432,186
Ensembl chr14:5,420,635...5,432,183
JBrowse link
G Suco SUN domain containing ossification factor involved_in IEA
IBA
ISO
ISS
GO_REF:0000107
GO_REF:0000033
(MGI:4452525|PMID:20440000)
GO_REF:0000024
Ensembl
GO_Central
RGD
UniProt
PMID:20440000 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:4452525 NCBI chr13:74,192,808...74,257,896
Ensembl chr13:74,193,573...74,257,896
JBrowse link
G Syt7 synaptotagmin 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:3798323|PMID:18539119)
UniProt
RGD
PMID:18539119 GO_REF:0000024 MGI:3798323 NCBI chr 1:207,031,359...207,093,787
Ensembl chr 1:207,031,592...207,089,026
JBrowse link
regulation of bone resorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calcr calcitonin receptor NOT|acts_upstream_of_or_within ISO MGI:3038975 (PMID:14970190) RGD PMID:14970190 NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392
JBrowse link
G Car2 carbonic anhydrase 2 TAS RGD PMID:9665810 RGD:1342423 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in IMP PMID:17121910 UniProt PMID:17121910 RGD:2293713 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Il20ra interleukin 20 receptor subunit alpha acts_upstream_of_or_within ISO MGI:5302406 (PMID:21844205) RGD PMID:21844205 NCBI chr 1:14,424,215...14,494,226
Ensembl chr 1:14,451,228...14,493,602
JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
GO_REF:0000024
MGI:1857478 (PMID:17053831)
GO_REF:0000107
HGNC-UCL
RGD
Ensembl
PMID:17053831 GO_REF:0000024 GO_REF:0000107 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 involved_in ISO
IEA
(MGI:5303050|PMID:21803180)
GO_REF:0000107
RGD
Ensembl
PMID:21803180 GO_REF:0000107 MGI:5303050 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3839226|PMID:19204730)
UniProt
RGD
PMID:19204730 GO_REF:0000024 MGI:3839226 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
G Siglec15 sialic acid binding Ig-like lectin 15 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:22451653)
GO_Central
RGD
PMID:22451653 GO_REF:0000033 NCBI chr18:71,506,416...71,521,894
Ensembl chr18:71,505,399...71,521,881
JBrowse link
G Slc4a2 solute carrier family 4 member 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5469753|PMID:23341620)
UniProt
RGD
PMID:23341620 GO_REF:0000024 MGI:5469753 NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19870
    multicellular organismal process 8843
      tissue remodeling 229
        bone remodeling 113
          bone resorption + 82
          negative regulation of bone remodeling + 21
          ossification involved in bone remodeling 3
          positive regulation of bone remodeling 0
          regulation of bone remodeling + 65
paths to the root