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ONTOLOGY REPORT - ANNOTATIONS


Term:microtubule polymerization
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Accession:GO:0046785 term browser browse the term
Definition:The addition of tubulin heterodimers to one or both ends of a microtubule.
Synonyms:exact_synonym: microtubule assembly
 related_synonym: microtubule formation


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microtubule polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 ISO RGD PMID:16480946 RGD:1582162 NCBI chrNW_004936589:2,504,235...2,536,778 JBrowse link
G Cenpj centromere protein J involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936720:2,149,296...2,201,599 JBrowse link
G Ckap5 cytoskeleton associated protein 5 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936562:2,269,341...2,369,098 JBrowse link
G Fbxo5 F-box protein 5 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3701159|PMID:17190794) MGI
Ensembl
PMID:17190794 GO_REF:0000107 MGI:3701159 NCBI chrNW_004936489:5,589,621...5,602,221 JBrowse link
G Fgf13 fibroblast growth factor 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936513:8,419,588...8,911,010 JBrowse link
G LOC101955940 HDGF like 3 involved_in ISO (MGI:3849122|PMID:19237540) UniProt PMID:19237540 MGI:3849122 NCBI chrNW_004936483:17,769,831...17,830,541 JBrowse link
G LOC101956723 tubulin polymerization promoting protein involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936815:842,279...882,985 JBrowse link
G Map7d3 MAP7 domain containing 3 involved_in ISO (PMID:24927501) UniProt PMID:24927501 NCBI chrNW_004936513:10,989,123...11,021,086 JBrowse link
G Mapre1 microtubule associated protein RP/EB family member 1 involved_in ISO (MGI:6355670|PMID:24706950) UniProt PMID:24706950 MGI:6355670 NCBI chrNW_004936485:19,577,859...19,608,036 JBrowse link
G Mapt microtubule associated protein tau involved_in ISO (PMID:26996940) ARUK-UCL PMID:26996940 NCBI chrNW_004936541:2,381,411...2,479,984 JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 NOT|involved_in ISO (PMID:26996940) ARUK-UCL PMID:26996940 NCBI chrNW_004936659:309,530...321,294 JBrowse link
G Tppp3 tubulin polymerization promoting protein family member 3 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936475:17,845,235...17,849,694 JBrowse link
G Trpv4 transient receptor potential cation channel subfamily V member 4 involved_in ISO PMID:20657843 BHF-UCL PMID:20657843 RGD:8553293 NCBI chrNW_004936769:1,424,526...1,447,547 JBrowse link
astral microtubule nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpj centromere protein J acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:11003675) MGI
Ensembl
PMID:11003675 GO_REF:0000107 NCBI chrNW_004936720:2,149,296...2,201,599 JBrowse link
centrosome-templated microtubule nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cep192 centrosomal protein 192 involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936626:2,565,302...2,659,863 JBrowse link
G Nin ninein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3575622|PMID:15784680) MGI
Ensembl
PMID:15784680 GO_REF:0000107 MGI:3575622 NCBI chrNW_004936495:14,791,246...14,897,454 JBrowse link
microtubule nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap9 A-kinase anchoring protein 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936621:2,247,082...2,374,407 JBrowse link
G Ccdc57 coiled-coil domain containing 57 involved_in ISO (PMID:32402286) UniProt PMID:32402286 NCBI chrNW_004936594:5,648,250...5,687,880 JBrowse link
G Clasp1 cytoplasmic linker associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936469:49,067,357...49,335,212 JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:17543864) UniProt PMID:17543864 NCBI chrNW_004936473:23,756,291...23,940,966 JBrowse link
G Csnk1d casein kinase 1 delta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936594:5,720,887...5,743,206 JBrowse link
G Golga2 golgin A2 involved_in ISO (PMID:19242490)
(PMID:26165940)
UniProt PMID:19242490 PMID:26165940 NCBI chrNW_004936487:15,798,623...15,814,360 JBrowse link
G LOC101969275 tubulin gamma-1 chain involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936490:17,357,782...17,363,006 JBrowse link
G Nde1 nudE neurodevelopment protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1928549|PMID:11163258) MGI
Ensembl
PMID:11163258 GO_REF:0000107 MGI:1928549 NCBI chrNW_004936501:3,193,962...3,234,640 JBrowse link
G Slain2 SLAIN motif family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936482:14,396,635...14,455,204 JBrowse link
G Tpx2 TPX2 microtubule nucleation factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:18,718,801...18,773,315 JBrowse link
G Tubg2 tubulin gamma 2 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936490:17,392,613...17,398,000 JBrowse link
G Tubgcp2 tubulin gamma complex associated protein 2 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936486:19,404,651...19,423,601 JBrowse link
G Tubgcp3 tubulin gamma complex associated protein 3 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936472:896,513...965,410 JBrowse link
G Tubgcp4 tubulin gamma complex associated protein 4 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936471:6,542,295...6,588,484 JBrowse link
G Tubgcp5 tubulin gamma complex associated protein 5 involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936471:38,180,670...38,215,972 JBrowse link
G Tubgcp6 tubulin gamma complex associated protein 6 involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936629:568,014...587,726 JBrowse link
microtubule nucleation by microtubule organizing center term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101956723 tubulin polymerization promoting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936815:842,279...882,985 JBrowse link
negative regulation of microtubule nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef7 Rho guanine nucleotide exchange factor 7 involved_in ISO (PMID:27012601) UniProt PMID:27012601 NCBI chrNW_004936472:1,784,215...1,857,296 JBrowse link
negative regulation of microtubule polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Capzb capping actin protein of muscle Z-line subunit beta acts_upstream_of_or_within ISO (MGI:4397629|PMID:19806181) MGI PMID:19806181 MGI:4397629 NCBI chrNW_004936474:5,594,193...5,656,665 JBrowse link
G Cdh5 cadherin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:16,738,772...16,775,000 JBrowse link
G Clip3 CAP-Gly domain containing linker protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936922:50,230...63,215 JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936500:5,317,109...5,423,593 JBrowse link
G Eml2 EMAP like 2 involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936706:2,018,951...2,044,695 JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 ISO RGD PMID:17435176 RGD:5508373 NCBI chrNW_004936606:3,122,798...3,131,352 JBrowse link
G Inpp5j inositol polyphosphate-5-phosphatase J ISO RGD PMID:16280363 RGD:2312436 NCBI chrNW_004936755:297,016...307,103 JBrowse link
G Map2 microtubule associated protein 2 involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004936845:475,406...752,600 JBrowse link
G Mapre1 microtubule associated protein RP/EB family member 1 involved_in ISO (PMID:11943150) UniProt PMID:11943150 NCBI chrNW_004936485:19,577,859...19,608,036 JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 ISO RGD PMID:16982696 RGD:1642763 NCBI chrNW_004936560:1,979,804...2,009,167 JBrowse link
G Snca synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936685:2,077,017...2,175,298 JBrowse link
G Stmn1 stathmin 1 involved_in
acts_upstream_of_or_within
ISO (PMID:25198505)
(MGI:3529385|PMID:15652749)
CAFA
MGI
PMID:15652749 PMID:25198505 MGI:3529385 NCBI chrNW_004936474:10,470,006...10,475,557 JBrowse link
G Stmn2 stathmin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936871:519,611...572,429 JBrowse link
G Tbcd tubulin folding cofactor D involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936923:239,029...366,503 JBrowse link
G Tubb4a tubulin beta 4A class IVa involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:3,821,171...3,826,827 JBrowse link
positive regulation of microtubule nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ckap5 cytoskeleton associated protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936562:2,269,341...2,369,098 JBrowse link
G Dctn1 dynactin subunit 1 involved_in ISO (PMID:23874158) UniProt PMID:23874158 NCBI chrNW_004936556:601,550...632,321 JBrowse link
G Git1 GIT ArfGAP 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:5,684,660...5,694,779 JBrowse link
G LOC101955831 heat shock 70 kDa protein 1 involved_in ISO (PMID:27137183) UniProt PMID:27137183 NCBI chrNW_004936727:1,718,952...1,721,691 JBrowse link
G LOC101956126 heat shock 70 kDa protein 1 involved_in ISO (PMID:27137183) UniProt PMID:27137183 NCBI chrNW_004936727:1,732,323...1,735,128 JBrowse link
G Mecp2 methyl-CpG binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936809:902,938...967,771 JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936498:6,001,126...6,135,663 JBrowse link
positive regulation of microtubule polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap9 A-kinase anchoring protein 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936621:2,247,082...2,374,407 JBrowse link
G Ankrd53 ankyrin repeat domain 53 involved_in ISO (PMID:26820536) UniProt PMID:26820536 NCBI chrNW_004936491:15,149,146...15,153,961 JBrowse link
G Apc APC regulator of WNT signaling pathway acts_upstream_of_or_within ISO (MGI:3656452|PMID:16525027) MGI PMID:16525027 MGI:3656452 NCBI chrNW_004936531:6,899,580...7,019,016 JBrowse link
G Arl2 ADP ribosylation factor like GTPase 2 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936599:4,336,190...4,343,007 JBrowse link
G Arl3 ADP ribosylation factor like GTPase 3 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936600:3,190,212...3,229,831 JBrowse link
G Cav1 caveolin 1 ISO RGD PMID:16480946 RGD:1582162 NCBI chrNW_004936589:2,504,235...2,536,778 JBrowse link
G Cav3 caveolin 3 ISO RGD PMID:16480946 RGD:1582162 NCBI chrNW_004936602:4,264,896...4,278,160 JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936487:8,900,375...9,081,547 JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3529385|PMID:15652749) MGI
Ensembl
PMID:15652749 GO_REF:0000107 MGI:3529385 NCBI chrNW_004936587:4,573,166...4,578,480 JBrowse link
G Clip1 CAP-Gly domain containing linker protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:2,109,569...2,224,907 JBrowse link
G Dctn1 dynactin subunit 1 involved_in ISO (PMID:23874158)
(PMID:16505168)
UniProt
ARUK-UCL
PMID:16505168 PMID:23874158 NCBI chrNW_004936556:601,550...632,321 JBrowse link
G Drg1 developmentally regulated GTP binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936755:557,862...583,204 JBrowse link
G Fes FES proto-oncogene, tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936483:16,123,938...16,135,044 JBrowse link
G Gda guanine deaminase involved_in ISO PMID:14730308 CACAO PMID:14730308 RGD:10047353 NCBI chrNW_004936503:8,191,925...8,279,806 JBrowse link
G Map1b microtubule associated protein 1B ISO RGD PMID:11896150 RGD:71122 NCBI chrNW_004936549:4,266,371...4,371,579 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO RGD PMID:16618812 RGD:1582322 NCBI chrNW_004936728:1,775,746...1,893,895 JBrowse link
G Mapre1 microtubule associated protein RP/EB family member 1 involved_in ISO (PMID:29162697) UniProt PMID:29162697 NCBI chrNW_004936485:19,577,859...19,608,036 JBrowse link
G Mapt microtubule associated protein tau involved_in ISO (PMID:1421571), (PMID:7706316) UniProt PMID:1421571 PMID:7706316 NCBI chrNW_004936541:2,381,411...2,479,984 JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936589:2,280,803...2,390,179 JBrowse link
G Nav3 neuron navigator 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936568:5,694,326...6,275,112 JBrowse link
G Nin ninein acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5629993|PMID:25741725) MGI
Ensembl
PMID:25741725 GO_REF:0000107 MGI:5629993 NCBI chrNW_004936495:14,791,246...14,897,454 JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936498:1,358,598...1,438,041 JBrowse link
G Ocln occludin involved_in ISO (PMID:20152177) ARUK-UCL PMID:20152177 NCBI chrNW_004936480:99,516...152,834 JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936498:6,001,126...6,135,663 JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936704:805,864...810,035 JBrowse link
G Rac1 Rac family small GTPase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936750:107,689...122,679 JBrowse link
G Rps3 ribosomal protein S3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936498:4,198,189...4,204,531 JBrowse link
G Slain2 SLAIN motif family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936482:14,396,635...14,455,204 JBrowse link
G Togaram1 TOG array regulator of axonemal microtubules 1 involved_in ISO (MGI:5796072|PMID:26378256) UniProt PMID:26378256 MGI:5796072 NCBI chrNW_004936583:4,213,853...4,298,916 JBrowse link
regulation of microtubule nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eml2 EMAP like 2 involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936706:2,018,951...2,044,695 JBrowse link
regulation of microtubule nucleation by Ran protein signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rangrf RAN guanine nucleotide release factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:1,513,855...1,515,300 JBrowse link
regulation of microtubule polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936487:17,690,206...17,819,619 JBrowse link
G Arl2 ADP ribosylation factor like GTPase 2 involved_in ISO (PMID:16525022) UniProt PMID:16525022 NCBI chrNW_004936599:4,336,190...4,343,007 JBrowse link
G Camsap1 calmodulin regulated spectrin associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936669:1,785,229...1,831,876 JBrowse link
G Camsap2 calmodulin regulated spectrin associated protein family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936567:3,497,304...3,590,967 JBrowse link
G Camsap3 calmodulin regulated spectrin associated protein family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:4,660,664...4,669,836 JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:24520051) UniProt PMID:24520051 NCBI chrNW_004936473:23,756,291...23,940,966 JBrowse link
G Gba2 glucosylceramidase beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936524:3,730,833...3,742,526 JBrowse link
G Mapre3 microtubule associated protein RP/EB family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936493:5,518,124...5,522,760 JBrowse link
G Prune1 prune exopolyphosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:1,231,197...1,253,686 JBrowse link
G Slain2 SLAIN motif family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936482:14,396,635...14,455,204 JBrowse link
G Slc39a12 solute carrier family 39 member 12 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5492261|PMID:23716681) MGI
Ensembl
PMID:23716681 GO_REF:0000107 MGI:5492261 NCBI chrNW_004936520:9,380,723...9,444,146 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14953
    cellular process 14088
      cellular component organization or biogenesis 5445
        cellular component organization 5316
          supramolecular fiber organization 658
            microtubule polymerization 82
              microtubule nucleation + 30
              negative regulation of microtubule polymerization + 16
              positive regulation of microtubule polymerization + 34
              regulation of microtubule polymerization + 59
Path 2
Term Annotations click to browse term
  biological_process 14953
    cellular process 14088
      cellular component organization or biogenesis 5445
        cellular component organization 5316
          organelle organization 3241
            cytoskeleton organization 1240
              microtubule cytoskeleton organization 554
                microtubule polymerization or depolymerization 122
                  microtubule polymerization 82
                    microtubule nucleation + 30
                    negative regulation of microtubule polymerization + 16
                    positive regulation of microtubule polymerization + 34
                    regulation of microtubule polymerization + 59
paths to the root