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ONTOLOGY REPORT - ANNOTATIONS

Term:decidualization
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Accession:GO:0046697 term browser browse the term
Definition:The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.
Synonyms:exact_synonym: decidual cell reaction
 xref: Wikipedia:Decidualization


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decidualization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASH1L ASH1 like histone lysine methyltransferase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26333994) Ensembl
MGI		 PMID:26333994 GO_REF:0000107 NCBI chr 1:155,335,268...155,563,202
Ensembl chr 1:155,335,268...155,563,162 		JBrowse link
G BSG basigin (Ok blood group) involved_in ISO
IEA		 RGD
Ensembl		 PMID:12141934 GO_REF:0000107 RGD:2289056 NCBI chr19:571,283...583,493
Ensembl chr19:571,277...583,494 		JBrowse link
G CDH1 cadherin 1 involved_in ISO (MGI:5430269|PMID:22378759) CACAO PMID:22378759 MGI:5430269 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16579983) Ensembl
MGI		 PMID:16579983 GO_REF:0000107 NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648 		JBrowse link
G CTSB cathepsin B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9310336) Ensembl
MGI		 PMID:9310336 GO_REF:0000107 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533 		JBrowse link
G CTSL cathepsin L acts_upstream_of_or_within ISO (PMID:9310336) RGD
MGI		 PMID:9310336 PMID:15644143 RGD:2315602 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469 		JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in IEP (PMID:16720713) BHF-UCL PMID:16720713 NCBI chr12:57,762,334...57,767,078
Ensembl chr12:57,762,334...57,768,986 		JBrowse link
G DCAF13 DDB1 and CUL4 associated factor 13 involved_in IEA
IDA		 (PMID:35932979) Ensembl
UniProt		 PMID:35932979 GO_REF:0000107 NCBI chr 8:103,415,386...103,443,453
Ensembl chr 8:103,414,714...103,443,453 		JBrowse link
G DEDD death effector domain containing involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21135503) Ensembl
MGI		 PMID:21135503 GO_REF:0000107 NCBI chr 1:161,120,974...161,132,667
Ensembl chr 1:161,120,974...161,132,688 		JBrowse link
G EPOR erythropoietin receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17300687) Ensembl
MGI		 PMID:17300687 GO_REF:0000107 NCBI chr19:11,377,207...11,384,314
Ensembl chr19:11,377,207...11,384,342 		JBrowse link
G ESR1 estrogen receptor 1 ISO RGD PMID:21248290 RGD:8553214 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide involved_in IDA (PMID:17494105) UniProt PMID:17494105 NCBI chr 3:10,285,666...10,292,947
Ensembl chr 3:10,285,666...10,292,947 		JBrowse link
G GHSR growth hormone secretagogue receptor involved_in IDA (PMID:17494105) UniProt PMID:17494105 NCBI chr 3:172,443,291...172,448,456
Ensembl chr 3:172,443,291...172,448,456 		JBrowse link
G GJA1 gap junction protein alpha 1 ISO RGD PMID:8924512 RGD:11568668 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GJB2 gap junction protein beta 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:1655436 PMID:8924512 GO_REF:0000107 RGD:11568668 RGD:7349399 NCBI chr13:20,187,470...20,192,938
Ensembl chr13:20,187,463...20,192,938 		JBrowse link
G IL11RA interleukin 11 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:9500603)
(PMID:9679067)		 MGI PMID:9500603 PMID:9679067 NCBI chr 9:34,652,185...34,661,902
Ensembl chr 9:34,652,162...34,661,902 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10022836) Ensembl
MGI		 PMID:10022836 GO_REF:0000107 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G KISS1 KiSS-1 metastasis suppressor acts_upstream_of_or_within ISO (PMID:24830702) MGI PMID:24830702 NCBI chr 1:204,190,341...204,196,491
Ensembl chr 1:204,190,341...204,196,491 		JBrowse link
G LIF LIF interleukin 6 family cytokine involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1522892) Ensembl
MGI		 PMID:1522892 GO_REF:0000107 NCBI chr22:30,240,453...30,246,759
Ensembl chr22:30,240,453...30,246,759 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO RGD PMID:21248290 RGD:8553214 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO RGD PMID:21248290 RGD:8553214 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MEN1 menin 1 ISO RGD PMID:19780023 RGD:9589138 NCBI chr11:64,803,516...64,811,294
Ensembl chr11:64,803,510...64,811,294 		JBrowse link
G NDP norrin cystine knot growth factor NDP involved_in ISO
IEA		 RGD
Ensembl		 PMID:21899531 GO_REF:0000107 RGD:8694207 NCBI chr  X:43,948,776...43,973,390
Ensembl chr  X:43,948,776...43,973,395 		JBrowse link
G NDRG3 NDRG family member 3 involved_in ISO (MGI:7388523|PMID:29096585) BHF-UCL PMID:29096585 MGI:7388523 NCBI chr20:36,651,771...36,746,090
Ensembl chr20:36,651,766...36,746,090 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PARP2 poly(ADP-ribose) polymerase 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:20,343,635...20,357,904
Ensembl chr14:20,343,615...20,357,904 		JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:10050766 RGD:1642479 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta involved_in ISO
TAS		 (PMID:11551955) RGD
UniProt		 PMID:11551955 PMID:12773104 RGD:2324898 NCBI chr 6:35,342,558...35,428,178
Ensembl chr 6:35,342,558...35,428,191 		JBrowse link
G PTGIS prostaglandin I2 synthase acts_upstream_of_or_within ISO (PMID:10385625) MGI PMID:10385625 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:10385625) RGD
MGI
Ensembl		 PMID:10385625 PMID:17485303 GO_REF:0000107 RGD:2300266 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTN pleiotrophin involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:137,227,341...137,343,733
Ensembl chr 7:137,227,341...137,343,774 		JBrowse link
G SERPINE1 serpin family E member 1 ISO RGD PMID:8862764 RGD:8547846 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SFRP4 secreted frizzled related protein 4 ISO RGD PMID:12063187 RGD:633927 NCBI chr 7:37,905,932...37,916,817
Ensembl chr 7:37,905,932...38,025,695 		JBrowse link
G SPP1 secreted phosphoprotein 1 involved_in TAS (PMID:16720713) BHF-UCL PMID:16720713 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G STC1 stanniocalcin 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:16735553 GO_REF:0000107 RGD:2324698 NCBI chr 8:23,841,929...23,854,806
Ensembl chr 8:23,841,929...23,854,806 		JBrowse link
G STC2 stanniocalcin 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:16735553 GO_REF:0000107 RGD:2324698 NCBI chr 5:173,314,723...173,328,414
Ensembl chr 5:173,314,723...173,328,447 		JBrowse link
G TCF23 transcription factor 23 acts_upstream_of_or_within IMP (PMID:24571987) MGI PMID:24571987 NCBI chr 2:27,149,004...27,156,974
Ensembl chr 2:27,149,004...27,156,974 		JBrowse link
G TPPP3 tubulin polymerization promoting protein family member 3 involved_in IMP (PMID:30667362) UniProt PMID:30667362 NCBI chr16:67,389,809...67,393,498
Ensembl chr16:67,389,809...67,393,518 		JBrowse link
G VDR vitamin D receptor involved_in IEP (PMID:16720713) BHF-UCL PMID:16720713 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
G VIM vimentin ISO RGD PMID:17653607 RGD:6480445 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19770
    developmental process 7667
      developmental process involved in reproduction 1384
        decidualization 40
Path 2
Term Annotations click to browse term
  biological_process 19770
    developmental process 7667
      anatomical structure development 7073
        animal organ development 3887
          placenta development 208
            maternal placenta development 53
              decidualization 40
paths to the root