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ONTOLOGY REPORT - ANNOTATIONS

Term:decidualization
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Accession:GO:0046697 term browser browse the term
Definition:The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.
Synonyms:exact_synonym: decidual cell reaction
 xref: Wikipedia:Decidualization


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decidualization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ash1l ASH1 like histone lysine methyltransferase acts_upstream_of_or_within ISO MGI:3852878 (MGI:5700615|PMID:26333994) RGD PMID:26333994 MGI:5700615 NCBI chr 2:174,346,267...174,483,057
Ensembl chr 2:174,346,150...174,483,055 		JBrowse link
G Bsg basigin (Ok blood group) IEP RGD PMID:12141934 RGD:2289056 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Cdh1 cadherin 1 involved_in ISO (MGI:5430269|PMID:22378759) RGD PMID:22378759 MGI:5430269 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 acts_upstream_of_or_within ISO MGI:2176158 (MGI:3628724|PMID:16579983) RGD PMID:16579983 MGI:3628724 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Ctsb cathepsin B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:88564 (MGI:1097032|PMID:9310336)		 Ensembl
RGD		 PMID:9310336 GO_REF:0000107 MGI:1097032 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsl cathepsin L acts_upstream_of_or_within IEP
ISO		 MGI:88561 (MGI:1097032|PMID:9310336) RGD PMID:9310336 PMID:15644143 MGI:1097032, RGD:2315602 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in ISO
IEA		 (PMID:16720713)
GO_REF:0000107		 RGD
Ensembl		 PMID:16720713 GO_REF:0000107 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Dedd death effector domain-containing acts_upstream_of_or_within ISO MGI:3707325 (MGI:5000188|PMID:21135503) RGD PMID:21135503 MGI:5000188 NCBI chr13:83,755,874...83,769,982
Ensembl chr13:83,756,108...83,769,332 		JBrowse link
G Epor erythropoietin receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3762687|PMID:17300687)		 Ensembl
RGD		 PMID:17300687 GO_REF:0000107 MGI:3762687 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257 		JBrowse link
G Esr1 estrogen receptor 1 IEP RGD PMID:21248290 RGD:8553214 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide involved_in ISO
ISS		 (PMID:17494105)
GO_REF:0000024		 RGD
UniProt		 PMID:17494105 GO_REF:0000024 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Ghsr growth hormone secretagogue receptor involved_in ISS
ISO		 GO_REF:0000024
(PMID:17494105)		 UniProt
RGD		 PMID:17494105 GO_REF:0000024 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
G Gja1 gap junction protein, alpha 1 IEP RGD PMID:8924512 RGD:11568668 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gjb2 gap junction protein, beta 2 IEP RGD PMID:1655436 PMID:8924512 RGD:7349399, RGD:11568668 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177 		JBrowse link
G Il11ra1 interleukin 11 receptor subunit alpha 1 acts_upstream_of_or_within ISO MGI:2177774|MGI:2177778 (MGI:1197428|PMID:9500603), (MGI:1276212|PMID:9679067) RGD PMID:9500603 PMID:9679067 MGI:1197428 MGI:1276212 NCBI chr 5:56,931,824...56,941,408
Ensembl chr 5:56,935,516...56,941,408 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2153821 (MGI:1332277|PMID:10022836)		 Ensembl
RGD		 PMID:10022836 GO_REF:0000107 MGI:1332277 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor acts_upstream_of_or_within ISO (MGI:5608658|PMID:24830702) RGD PMID:24830702 MGI:5608658 NCBI chr13:44,774,823...44,780,707
Ensembl chr13:44,774,823...44,780,612 		JBrowse link
G Lif LIF, interleukin 6 family cytokine involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2177780 (MGI:82525|PMID:1522892)		 Ensembl
RGD		 PMID:1522892 GO_REF:0000107 MGI:82525 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 IDA RGD PMID:21248290 RGD:8553214 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 IDA RGD PMID:21248290 RGD:8553214 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Men1 menin 1 IEP RGD PMID:19780023 RGD:9589138 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871 		JBrowse link
G Ndp norrin cystine knot growth factor NDP IEP RGD PMID:21899531 RGD:8694207 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Pla2g4a phospholipase A2 group IVA IMP RGD PMID:10050766 RGD:1642479 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta IEP RGD PMID:12773104 RGD:2324898 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Ptgis prostaglandin I2 synthase acts_upstream_of_or_within ISO (MGI:1340153|PMID:10385625) RGD PMID:10385625 MGI:1340153 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 acts_upstream_of_or_within IMP
ISO		 MGI:1857239 (MGI:1340153|PMID:10385625) RGD PMID:10385625 PMID:17485303 MGI:1340153, RGD:2300266 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptn pleiotrophin involved_in ISS
ISO		 GO_REF:0000024
(MGI:6294220|PMID:28657144)		 UniProt
RGD		 PMID:28657144 GO_REF:0000024 MGI:6294220 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456 		JBrowse link
G Serpine1 serpin family E member 1 IEP RGD PMID:8862764 RGD:8547846 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sfrp4 secreted frizzled-related protein 4 IEP RGD PMID:12063187 RGD:633927 NCBI chr17:45,278,867...45,330,806
Ensembl chr17:45,234,097...45,330,736 		JBrowse link
G Stc1 stanniocalcin 1 IEP RGD PMID:16735553 RGD:2324698 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264 		JBrowse link
G Stc2 stanniocalcin 2 IEP RGD PMID:16735553 RGD:2324698 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973 		JBrowse link
G Tcf23 transcription factor 23 acts_upstream_of_or_within ISO (PMID:24571987) RGD PMID:24571987 NCBI chr 6:25,397,889...25,406,639
Ensembl chr 6:25,397,937...25,405,880 		JBrowse link
G Tppp3 tubulin polymerization-promoting protein family member 3 involved_in ISO
ISS		 (PMID:30667362)
GO_REF:0000024		 RGD
UniProt		 PMID:30667362 GO_REF:0000024 NCBI chr19:33,345,897...33,349,610
Ensembl chr19:33,345,898...33,349,577 		JBrowse link
G Vdr vitamin D receptor involved_in ISO
IEA		 (PMID:16720713)
GO_REF:0000107		 RGD
Ensembl		 PMID:16720713 GO_REF:0000107 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
G Vim vimentin IEP RGD PMID:17653607 RGD:6480445 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    developmental process 6965
      developmental process involved in reproduction 1227
        decidualization 35
Path 2
Term Annotations click to browse term
  biological_process 19834
    developmental process 6965
      anatomical structure development 6376
        multicellular organism development 5800
          system development 5439
            reproductive system development 601
              reproductive structure development 596
                placenta development 199
                  maternal placenta development 48
                    decidualization 35
paths to the root