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ONTOLOGY REPORT - ANNOTATIONS

Term:folic acid metabolic process
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Accession:GO:0046655 term browser browse the term
Definition:The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
Synonyms:exact_synonym: folate metabolic process;   folate metabolism;   folic acid metabolism;   vitamin B9 metabolic process;   vitamin B9 metabolism;   vitamin M metabolic process;   vitamin M metabolism

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folic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhfr dihydrofolate reductase involved_in IBA
IDA		 PMID:21873635
PMID:20424322		 GO_Central
BHF-UCL		 PMID:21873635, PMID:20424322 RGD:13792537, RGD:10054082 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453 		JBrowse link
G Folr1 folate receptor alpha acts_upstream_of_or_within ISO MGI:2383986 (MGI:2669340|PMID:12854656) RGD PMID:12854656 MGI:2669340 NCBI chr 1:166,934,457...166,945,864
Ensembl chr 1:166,934,460...166,943,592 		JBrowse link
G Gnmt glycine N-methyltransferase TAS RGD PMID:12054489 RGD:728472 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5512657|PMID:24074862)
(PMID:11466310)		 UniProt
RGD		 PMID:11466310 PMID:24074862 GO_REF:0000024 MGI:5512657 NCBI chr 1:37,743,089...37,774,485
Ensembl chr 1:37,743,147...37,774,015 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in IBA
ISO		 PMID:21873635
(PMID:11278996)		 RGD PMID:11278996, PMID:21873635 RGD:13792537 NCBI chr10:47,030,813...47,059,216
Ensembl chr10:47,031,050...47,059,216 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:70,824,718...70,829,822
Ensembl chr 7:70,824,715...70,829,815 		JBrowse link
folic acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO (PMID:12764149) RGD PMID:12764149 NCBI chr 8:96,564,877...96,614,386
Ensembl chr 8:96,564,877...96,614,348 		JBrowse link
G Pm20d2 peptidase M20 domain containing 2 NOT|involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:48,416,005...48,437,054
Ensembl chr 5:48,420,302...48,436,531 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19634
    metabolic process 11911
      cellular metabolic process 10866
        cellular nitrogen compound metabolic process 6604
          cellular amide metabolic process 1530
            folic acid metabolic process 8
              folic acid biosynthetic process 0
              folic acid catabolic process 2
Path 2
Term Annotations click to browse term
  biological_process 19634
    metabolic process 11911
      cellular metabolic process 10866
        organic acid metabolic process 1004
          oxoacid metabolic process 966
            carboxylic acid metabolic process 948
              dicarboxylic acid metabolic process 104
                folic acid metabolic process 8
                  folic acid biosynthetic process 0
                  folic acid catabolic process 2
paths to the root