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ONTOLOGY REPORT - ANNOTATIONS

Term:folic acid metabolic process
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Accession:GO:0046655 term browser browse the term
Definition:The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
Synonyms:exact_synonym: folate metabolic process;   folate metabolism;   folic acid metabolism;   vitamin B9 metabolic process;   vitamin B9 metabolism;   vitamin M metabolic process;   vitamin M metabolism


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folic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 involved_in IDA PMID:1848231 UniProt PMID:1848231 RGD:632027 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465 		JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 involved_in ISO (MGI:6489626|PMID:33168096) RGD PMID:33168096 MGI:6489626 NCBI chr 7:20,254,196...20,305,793
Ensembl chr 7:20,254,233...20,305,776 		JBrowse link
G Dhfr dihydrofolate reductase involved_in IBA
IDA		 PMID:21873635
PMID:20424322		 GO_Central
BHF-UCL		 PMID:21873635 PMID:20424322 RGD:13792537, RGD:10054082 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Folr1 folate receptor alpha acts_upstream_of_or_within ISO MGI:2383986 (MGI:2669340|PMID:12854656) RGD PMID:12854656 MGI:2669340 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G Gnmt glycine N-methyltransferase TAS RGD PMID:12054489 RGD:728472 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5512657|PMID:24074862)
(PMID:11466310)		 UniProt
RGD		 PMID:11466310 PMID:24074862 GO_REF:0000024 MGI:5512657 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in IBA
ISO		 PMID:21873635
(PMID:11278996)		 RGD PMID:11278996 PMID:21873635 RGD:13792537 NCBI chr10:45,468,698...45,497,820
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236 		JBrowse link
folic acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO (PMID:12764149) RGD PMID:12764149 NCBI chr 8:89,729,498...89,801,998
Ensembl chr 8:89,729,508...89,799,089 		JBrowse link
G Pm20d2 peptidase M20 domain containing 2 NOT|involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:47,566,059...47,586,334
Ensembl chr 5:47,566,072...47,586,212 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    metabolic process 12042
      cellular metabolic process 10922
        cellular nitrogen compound metabolic process 6716
          cellular amide metabolic process 1563
            folic acid metabolic process 10
              folic acid biosynthetic process 0
              folic acid catabolic process 2
Path 2
Term Annotations click to browse term
  biological_process 19834
    metabolic process 12042
      cellular metabolic process 10922
        organic acid metabolic process 1026
          oxoacid metabolic process 993
            carboxylic acid metabolic process 972
              dicarboxylic acid metabolic process 99
                folic acid metabolic process 10
                  folic acid biosynthetic process 0
                  folic acid catabolic process 2
paths to the root