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ONTOLOGY REPORT - ANNOTATIONS


Term:folic acid metabolic process
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Accession:GO:0046655 term browser browse the term
Definition:The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
Synonyms:exact_synonym: folate metabolic process;   folate metabolism;   folic acid metabolism;   vitamin B9 metabolic process;   vitamin B9 metabolism;   vitamin M metabolic process;   vitamin M metabolism



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folic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 involved_in IDA PMID:1848231 UniProt PMID:1848231 RGD:632027 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 involved_in ISO (MGI:6489626|PMID:33168096) RGD PMID:33168096 MGI:6489626 NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776
JBrowse link
G Dhfr dihydrofolate reductase involved_in IDA
IBA
PMID:20424322
GO_REF:0000033
GO_Central PMID:20424322 GO_REF:0000033, RGD:10054082 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G ENSRNOG00000065410 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 2:178,497,468...178,499,169 JBrowse link
G Folr1 folate receptor alpha acts_upstream_of_or_within ISO MGI:2383986 (MGI:2669340|PMID:12854656) RGD PMID:12854656 MGI:2669340 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISS
ISO
GO_REF:0000024
(MGI:5512657|PMID:24074862)
(PMID:11466310)
UniProt
RGD
PMID:11466310 PMID:24074862 GO_REF:0000024 MGI:5512657 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in ISO (PMID:11278996) RGD PMID:11278996 NCBI chr10:45,468,698...45,490,833
Ensembl chr10:45,468,700...45,497,820
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
folic acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO (PMID:12764149) RGD PMID:12764149 NCBI chr 8:89,729,498...89,801,998
Ensembl chr 8:89,729,508...89,799,089
JBrowse link
G Pm20d2 peptidase M20 domain containing 2 NOT|involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:47,566,059...47,586,334
Ensembl chr 5:47,566,072...47,586,212
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20350
    metabolic process 11904
      nitrogen compound metabolic process 9700
        amide metabolic process 1657
          folic acid metabolic process 10
            folic acid biosynthetic process 0
            folic acid catabolic process 2
Path 2
Term Annotations click to browse term
  biological_process 20350
    metabolic process 11904
      cellular metabolic process 10470
        organic acid metabolic process 1075
          oxoacid metabolic process 1057
            carboxylic acid metabolic process 1038
              dicarboxylic acid metabolic process 108
                folic acid metabolic process 10
                  folic acid biosynthetic process 0
                  folic acid catabolic process 2
paths to the root