Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:tetrahydrofolate biosynthetic process
go back to main search page
Accession:GO:0046654 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.
Synonyms:exact_synonym: tetrahydrofolate anabolism;   tetrahydrofolate biosynthesis;   tetrahydrofolate formation;   tetrahydrofolate synthesis
 xref: MetaCyc:FOLSYN-PWY

show annotations for term's descendants           Sort by:
 
tetrahydrofolate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 TAS RGD PMID:14729668 RGD:1547843 NCBI chr 4:123,516,553...123,564,067
Ensembl chr 4:123,516,788...123,557,501 		JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase IDA RGD PMID:7057182 RGD:2301991 NCBI chr 9:78,862,013...78,882,061
Ensembl chr 9:78,862,013...78,882,060 		JBrowse link
G Dhfr dihydrofolate reductase IDA
IBA
ISO
IEA		 PMID:21873635
(PMID:2303423)
GO_REF:0000041		 RGD
UniProt		 PMID:2303423, PMID:11502523, PMID:21873635 GO_REF:0000041, RGD:1298877, RGD:13792537 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453 		JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase IDA RGD PMID:4078017 RGD:2301990 NCBI chr11:31,780,477...31,805,728
Ensembl chr11:31,780,487...31,805,728 		JBrowse link
G Gch1 GTP cyclohydrolase 1 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011 		JBrowse link
10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 ISO (PMID:1881876)
(MGI:5503248|PMID:23704330)		 RGD PMID:1881876 PMID:23704330 MGI:5503248 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340 		JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like ISO (PMID:12937168) RGD PMID:12937168 NCBI chr 1:40,529,092...40,719,232
Ensembl chr 1:40,529,045...40,719,391 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20045
    cellular process 18859
      cellular metabolic process 11041
        cellular modified amino acid metabolic process 204
          folic acid-containing compound metabolic process 28
            tetrahydrofolate metabolic process 21
              tetrahydrofolate biosynthetic process 7
                10-formyltetrahydrofolate biosynthetic process 2
Path 2
Term Annotations click to browse term
  biological_process 20045
    metabolic process 12102
      cellular metabolic process 11041
        heterocycle metabolic process 5631
          pteridine-containing compound metabolic process 34
            pteridine-containing compound biosynthetic process 15
              folic acid-containing compound biosynthetic process 9
                tetrahydrofolate biosynthetic process 7
                  10-formyltetrahydrofolate biosynthetic process 2
paths to the root