Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of alpha-beta T cell activation
go back to main search page
Accession:GO:0046636 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell activation.
Synonyms:exact_synonym: down regulation of alpha-beta T cell activation;   downregulation of alpha-beta T cell activation;   negative regulation of alpha-beta T lymphocyte activation
 narrow_synonym: inhibition of alpha-beta T cell activation



show annotations for term's descendants           Sort by:
 
negative regulation of alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor acts_upstream_of_or_within IDA (MGI:3822045|PMID:10069416) MGI PMID:10069416 MGI:3822045 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618
JBrowse link
G Vsir V-set immunoregulatory receptor involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr10:60,182,630...60,266,073
Ensembl chr10:60,182,630...60,208,463
JBrowse link
negative regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli3 GLI-Kruppel family member GLI3 involved_in IMP (MGI:4355451|PMID:19667090) BHF-UCL PMID:19667090 MGI:4355451 NCBI chr13:15,638,308...15,904,611
Ensembl chr13:15,637,820...15,904,611
JBrowse link
G Ihh Indian hedgehog involved_in IMP (MGI:3836494|PMID:19109233) BHF-UCL PMID:19109233 MGI:3836494 NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831
JBrowse link
G Shh sonic hedgehog acts_upstream_of_or_within IMP (MGI:1888832|PMID:10981962) MGI PMID:10981962 MGI:1888832 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254
JBrowse link
negative regulation of alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btla B and T lymphocyte associated acts_upstream_of_or_within IMP (MGI:3521631|PMID:15568026) MGI PMID:15568026 MGI:3521631 NCBI chr16:45,043,121...45,073,258
Ensembl chr16:45,044,678...45,078,033
JBrowse link
G Clec4g C-type lectin domain family 4, member g acts_upstream_of_or_within IMP (MGI:5475030|PMID:23487419) MGI PMID:23487419 MGI:5475030 NCBI chr 8:3,757,066...3,770,695
Ensembl chr 8:3,757,064...3,770,651
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within IMP (MGI:3692513|PMID:16945588) MGI PMID:16945588 MGI:3692513 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484
JBrowse link
G Tnfrsf14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 4:155,002,944...155,013,077
Ensembl chr 4:155,006,390...155,013,020
JBrowse link
negative regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Skint2 selection and upkeep of intraepithelial T cells 2 acts_upstream_of_or_within IDA (MGI:3830586|PMID:17339463) MGI PMID:17339463 MGI:3830586 NCBI chr 4:112,470,795...112,509,445
Ensembl chr 4:112,414,391...112,509,445
JBrowse link
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 7:3,535,015...3,551,159
Ensembl chr 7:3,535,016...3,551,140
JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:66,230,060...66,258,198
Ensembl chr17:66,228,967...66,258,221
JBrowse link
negative regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbfb core binding factor beta involved_in IMP (MGI:3772948|PMID:18258917) UniProt PMID:18258917 MGI:3772948 NCBI chr 8:105,897,230...105,944,621
Ensembl chr 8:105,897,306...105,944,621
JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299
JBrowse link
G Runx1 runt related transcription factor 1 involved_in IDA (MGI:3772948|PMID:18258917) UniProt PMID:18258917 MGI:3772948 NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037
JBrowse link
G Runx3 runt related transcription factor 3 involved_in IMP (MGI:3772948|PMID:18258917) UniProt PMID:18258917 MGI:3772948 NCBI chr 4:134,847,956...134,905,301
Ensembl chr 4:134,847,963...134,905,301
JBrowse link
negative regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase type II involved_in IMP (MGI:5908533|PMID:25009204) UniProt PMID:25009204 MGI:5908533 NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075
JBrowse link
G Cblb Casitas B-lineage lymphoma b acts_upstream_of_or_within IMP (MGI:3038342|PMID:14973438) MGI PMID:14973438 MGI:3038342 NCBI chr16:51,851,593...52,028,410
Ensembl chr16:51,851,588...52,028,411
JBrowse link
G Cd274 CD274 antigen involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
JBrowse link
G Cd44 CD44 antigen involved_in IMP (MGI:5688819|PMID:25065622) UniProt PMID:25065622 MGI:5688819 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within IDA (MGI:3697020|PMID:17028180) MGI PMID:17028180 MGI:3697020 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484
JBrowse link
G Itch itchy, E3 ubiquitin protein ligase acts_upstream_of_or_within IMP (MGI:3038342|PMID:14973438) MGI PMID:14973438 MGI:3038342 NCBI chr 2:154,975,401...155,068,775
Ensembl chr 2:154,975,429...155,068,775
JBrowse link
G Lgals7 lectin, galactose binding, soluble 7 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 7:28,563,221...28,565,710
Ensembl chr 7:28,563,278...28,565,709
JBrowse link
G Lgals9 lectin, galactose binding, soluble 9 involved_in IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:5688819|PMID:25065622)
GO_Central
UniProt
PMID:21873635 PMID:25065622 MGI:5688819 MGI:6201960 NCBI chr11:78,853,805...78,875,750
Ensembl chr11:78,853,800...78,875,772
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within IMP (MGI:3694584|PMID:17137798) MGI PMID:17137798 MGI:3694584 NCBI chr18:38,551,960...38,598,250
Ensembl chr18:38,543,449...38,598,356
JBrowse link
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 involved_in IDA (MGI:5908526|PMID:26311901) UniProt PMID:26311901 MGI:5908526 NCBI chr 7:3,535,015...3,551,159
Ensembl chr 7:3,535,016...3,551,140
JBrowse link
G Tnfrsf14 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) acts_upstream_of_or_within IDA (MGI:3521631|PMID:15568026) MGI PMID:15568026 MGI:3521631 NCBI chr 4:155,002,944...155,013,077
Ensembl chr 4:155,006,390...155,013,020
JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:66,230,060...66,258,198
Ensembl chr17:66,228,967...66,258,221
JBrowse link
G Vsir V-set immunoregulatory receptor involved_in
acts_upstream_of_or_within
ISO
IDA
(MGI:5292805|PMID:21383057) MGI PMID:21383057 GO_REF:0000096 MGI:4834177 MGI:5292805 NCBI chr10:60,182,630...60,266,073
Ensembl chr10:60,182,630...60,208,463
JBrowse link
G Xcl1 chemokine (C motif) ligand 1 involved_in ISO (PMID:10887101) BHF-UCL PMID:10887101 NCBI chr 1:164,759,213...164,763,091
Ensembl chr 1:164,759,213...164,763,096
JBrowse link
negative regulation of CD8-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 antigen involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
JBrowse link
G Hfe homeostatic iron regulator involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr13:23,886,017...23,894,837
Ensembl chr13:23,886,017...23,894,837
JBrowse link
G Skint2 selection and upkeep of intraepithelial T cells 2 acts_upstream_of_or_within IDA (MGI:3830586|PMID:17339463) MGI PMID:17339463 MGI:3830586 NCBI chr 4:112,470,795...112,509,445
Ensembl chr 4:112,414,391...112,509,445
JBrowse link
negative regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Socs1 suppressor of cytokine signaling 1 involved_in IMP (MGI:6140589|PMID:24880459) UniProt PMID:24880459 MGI:6140589 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400
JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B involved_in IMP (MGI:5446998|PMID:22730529), (MGI:6140589|PMID:24880459) UniProt PMID:22730529 PMID:24880459 MGI:5446998 MGI:6140589 NCBI chr 3:89,284,951...89,300,980
Ensembl chr 3:89,284,951...89,302,083
JBrowse link
negative regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vsir V-set immunoregulatory receptor involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr10:60,182,630...60,266,073
Ensembl chr10:60,182,630...60,208,463
JBrowse link
negative regulation of NK T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a CD300A molecule involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:114,780,006...114,792,772
Ensembl chr11:114,780,867...114,795,480
JBrowse link
negative regulation of NK T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb7b zinc finger and BTB domain containing 7B involved_in IMP (MGI:5449456|PMID:23105140) UniProt PMID:23105140 MGI:5449456 NCBI chr 3:89,284,951...89,300,980
Ensembl chr 3:89,284,951...89,302,083
JBrowse link
negative regulation of T-helper 1 cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xcl1 chemokine (C motif) ligand 1 involved_in ISO (PMID:10887101) BHF-UCL PMID:10887101 NCBI chr 1:164,759,213...164,763,091
Ensembl chr 1:164,759,213...164,763,096
JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4ra interleukin 4 receptor, alpha acts_upstream_of_or_within IGI (MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:3761239 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646
JBrowse link
G Jak3 Janus kinase 3 involved_in IMP (MGI:3719947|PMID:16020505) BHF-UCL PMID:16020505 MGI:3719947 NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219
JBrowse link
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 involved_in IDA (MGI:4942267|PMID:9670042) BHF-UCL PMID:9670042 MGI:4942267 NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981
JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484
JBrowse link
G Il2 interleukin 2 involved_in IGI (MGI:5634593|PMID:25642768) BHF-UCL PMID:25642768 MGI:5634593 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within
involved_in
IDA
IBA
(MGI:3817792|PMID:18792410)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:18792410 PMID:21873635 MGI:3817792 MGI:6201960 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Rc3h1 RING CCCH (C3H) domains 1 involved_in IMP (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr 1:160,733,981...160,802,546
Ensembl chr 1:160,733,988...160,802,548
JBrowse link
G Rc3h2 ring finger and CCCH-type zinc finger domains 2 involved_in IMP (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr 2:37,260,078...37,313,007
Ensembl chr 2:37,260,081...37,312,915
JBrowse link
G Smad7 SMAD family member 7 involved_in IMP (MGI:5634593|PMID:25642768) BHF-UCL PMID:25642768 MGI:5634593 NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006
JBrowse link
G Tbx21 T-box 21 involved_in IDA (MGI:4868293|PMID:21151104) UniProt PMID:21151104 MGI:4868293 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157
JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within IMP (MGI:5450776|PMID:23034280) MGI PMID:23034280 MGI:5450776 NCBI chr 3:89,284,951...89,300,980
Ensembl chr 3:89,284,951...89,302,083
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in IMP (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr 4:125,012,207...125,021,674
Ensembl chr 4:125,012,216...125,021,633
JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Loxl3 lysyl oxidase-like 3 involved_in IMP (MGI:5825383|PMID:28065600) UniProt PMID:28065600 MGI:5825383 NCBI chr 6:83,011,186...83,029,547
Ensembl chr 6:83,011,154...83,029,543
JBrowse link
G Tbx21 T-box 21 involved_in IMP (MGI:4868293|PMID:21151104) UniProt PMID:21151104 MGI:4868293 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157
JBrowse link
G Tnfsf18 tumor necrosis factor (ligand) superfamily, member 18 involved_in IMP (MGI:5551556|PMID:24107315) UniProt PMID:24107315 MGI:5551556 NCBI chr 1:161,322,226...161,332,859
Ensembl chr 1:161,322,224...161,332,859
JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
JBrowse link
G Bcl6 B cell leukemia/lymphoma 6 acts_upstream_of_or_within IGI (MGI:2450484|PMID:12594267) MGI PMID:12594267 MGI:2450484 NCBI chr16:23,783,800...23,807,623
Ensembl chr16:23,783,802...23,807,602
JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within IGI
IMP
(MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:3761239 NCBI chr 1:184,459,340...184,464,690
Ensembl chr 1:184,459,337...184,464,816
JBrowse link
G Irf1 interferon regulatory factor 1 involved_in TAS (MGI:5319622|PMID:11244049) UniProt PMID:11244049 MGI:5319622 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in IDA (MGI:3687909|PMID:12242343) UniProt PMID:12242343 MGI:3687909 NCBI chr17:87,414,707...87,445,153
Ensembl chr17:87,415,107...87,445,267
JBrowse link
G Zfp35 zinc finger protein 35 acts_upstream_of_or_within IMP (MGI:4366385|PMID:19783676) MGI PMID:19783676 MGI:4366385 NCBI chr18:24,122,134...24,138,428
Ensembl chr18:24,122,689...24,138,433
JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rc3h1 RING CCCH (C3H) domains 1 acts_upstream_of_or_within IMP (MGI:3580753|PMID:15917799) MGI PMID:15917799 MGI:3580753 NCBI chr 1:160,733,981...160,802,546
Ensembl chr 1:160,733,988...160,802,548
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28742
    immune system process 2937
      leukocyte activation 1198
        lymphocyte activation 1004
          T cell activation 618
            alpha-beta T cell activation 201
              negative regulation of alpha-beta T cell activation 47
                negative regulation of CD4-positive, alpha-beta T cell activation + 38
                negative regulation of CD8-positive, alpha-beta T cell activation + 6
                negative regulation of NK T cell activation + 2
                negative regulation of alpha-beta T cell differentiation + 28
                negative regulation of alpha-beta T cell proliferation + 17
Path 2
Term Annotations click to browse term
  biological_process 28742
    biological regulation 13657
      regulation of biological process 12986
        regulation of cellular process 12226
          regulation of cell adhesion 872
            regulation of cell-cell adhesion 534
              regulation of leukocyte cell-cell adhesion 406
                negative regulation of leukocyte cell-cell adhesion 171
                  negative regulation of T cell activation 148
                    negative regulation of alpha-beta T cell activation 47
                      negative regulation of CD4-positive, alpha-beta T cell activation + 38
                      negative regulation of CD8-positive, alpha-beta T cell activation + 6
                      negative regulation of NK T cell activation + 2
                      negative regulation of alpha-beta T cell differentiation + 28
                      negative regulation of alpha-beta T cell proliferation + 17
paths to the root