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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of alpha-beta T cell activation
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Accession:GO:0046634 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of alpha-beta T cell activation.
Synonyms:exact_synonym: regulation of alpha-beta T lymphocyte activation


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CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 CD81 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936794:664,089...670,294 JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4819294|PMID:20639485) BHF-UCL PMID:20639485 MGI:4819294 NCBI chrNW_004936481:14,391,359...14,409,514 JBrowse link
negative regulation of alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3822045|PMID:10069416) MGI
Ensembl
PMID:10069416 GO_REF:0000107 MGI:3822045 NCBI chrNW_004936619:597,970...618,564 JBrowse link
negative regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli3 GLI family zinc finger 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936478:17,129,922...17,403,630 JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936569:1,474,693...1,480,562 JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1888832|PMID:10981962) MGI
Ensembl
PMID:10981962 GO_REF:0000107 MGI:1888832 NCBI chrNW_004936527:10,033,095...10,042,713 JBrowse link
negative regulation of alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btla B and T lymphocyte associated acts_upstream_of_or_within ISO (MGI:3521631|PMID:15568026) MGI PMID:15568026 MGI:3521631 NCBI chrNW_004936536:155,401...183,039 JBrowse link
G Clec4g C-type lectin domain family 4 member G acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5475030|PMID:23487419) MGI
Ensembl
PMID:23487419 GO_REF:0000107 MGI:5475030 NCBI chrNW_004936588:4,737,278...4,740,750 JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3692513|PMID:16945588) MGI
Ensembl
PMID:16945588 GO_REF:0000107 MGI:3692513 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
negative regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Twsg1 twisted gastrulation BMP signaling modulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936626:1,901,686...1,946,554 JBrowse link
negative regulation of CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd160 CD160 molecule involved_in ISO (PMID:18193050) UniProt PMID:18193050 NCBI chrNW_004936867:478,625...485,905 JBrowse link
negative regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbfb core-binding factor subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:17,537,273...17,589,383 JBrowse link
G Hmgb1 high mobility group box 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936472:25,236,728...25,246,585 JBrowse link
G Runx3 RUNX family transcription factor 3 involved_in ISO (MGI:3772948|PMID:18258917) UniProt PMID:18258917 MGI:3772948 NCBI chrNW_004936474:9,751,946...9,802,910 JBrowse link
negative regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936495:11,004,296...11,045,467 JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3038342|PMID:14973438) MGI
Ensembl
PMID:14973438 GO_REF:0000107 MGI:3038342 NCBI chrNW_004936701:1,157,790...1,353,375 JBrowse link
G Cd274 CD274 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936539:132,870...145,288 JBrowse link
G Cd44 CD44 molecule (Indian blood group) involved_in ISO (MGI:5688819|PMID:25065622) UniProt PMID:25065622 MGI:5688819 NCBI chrNW_004936533:2,949,026...3,033,166 JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3697020|PMID:17028180) MGI
Ensembl
PMID:17028180 GO_REF:0000107 MGI:3697020 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Itch itchy E3 ubiquitin protein ligase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3038342|PMID:14973438) MGI
Ensembl
PMID:14973438 GO_REF:0000107 MGI:3038342 NCBI chrNW_004936561:6,140,236...6,265,734 JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:20209097)
(MGI:5688819|PMID:25065622)
UniProt PMID:20209097 PMID:25065622 MGI:5688819 NCBI chrNW_004936538:4,034,467...4,050,240 JBrowse link
G LOC101970885 lymphotactin involved_in ISO (PMID:10887101) BHF-UCL PMID:10887101 NCBI chrNW_004936481:17,825,714...17,828,955 JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO (MGI:3694584|PMID:17137798) MGI PMID:17137798 MGI:3694584 NCBI chrNW_004936504:12,053,470...12,103,346 JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 acts_upstream_of_or_within ISO (MGI:3521631|PMID:15568026) MGI PMID:15568026 MGI:3521631 NCBI chrNW_004936737:1,008,228...1,013,575 JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936626:1,901,686...1,946,554 JBrowse link
negative regulation of CD8-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936539:132,870...145,288 JBrowse link
G Hfe homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936671:1,940,079...1,947,574 JBrowse link
negative regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Socs1 suppressor of cytokine signaling 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936530:9,312,965...9,315,593 JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:4,546,139...4,560,157 JBrowse link
negative regulation of NK T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb7b zinc finger and BTB domain containing 7B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:4,546,139...4,560,157 JBrowse link
negative regulation of T-helper 1 cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101970885 lymphotactin involved_in ISO (PMID:10887101) BHF-UCL PMID:10887101 NCBI chrNW_004936481:17,825,714...17,828,955 JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO (MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:3761239 NCBI chrNW_004936501:11,025,590...11,058,807 JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (MGI:3719947|PMID:16020505) BHF-UCL PMID:16020505 MGI:3719947 NCBI chrNW_004936596:3,212,593...3,224,426 JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4942267|PMID:9670042) BHF-UCL PMID:9670042 MGI:4942267 NCBI chrNW_004936481:14,391,359...14,409,514 JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Il2 interleukin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936662:1,594,953...1,599,625 JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936481:13,919,006...13,973,868 JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936487:11,341,663...11,393,275 JBrowse link
G Smad7 SMAD family member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:13,894,586...13,921,978 JBrowse link
G Tbx21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:13,546,405...13,558,635 JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5450776|PMID:23034280) MGI
Ensembl
PMID:23034280 GO_REF:0000107 MGI:5450776 NCBI chrNW_004936580:4,546,139...4,560,157 JBrowse link
G Zc3h12a zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:19,714,145...19,722,512 JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Loxl3 lysyl oxidase like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936556:745,798...765,926 JBrowse link
G Tbx21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:13,546,405...13,558,635 JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936481:14,499,495...14,508,074 JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936503:9,124,314...9,142,372 JBrowse link
G Bcl6 BCL6 transcription repressor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2450484|PMID:12594267) MGI
Ensembl
PMID:12594267 GO_REF:0000107 MGI:2450484 NCBI chrNW_004936578:2,371,976...2,395,034 JBrowse link
G Hlx H2.0 like homeobox acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3761239|PMID:16424184) MGI
Ensembl
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chrNW_004936650:1,416,825...1,422,595 JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936508:5,531,002...5,588,022 JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rc3h1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3580753|PMID:15917799) MGI
Ensembl
PMID:15917799 GO_REF:0000107 MGI:3580753 NCBI chrNW_004936481:13,919,006...13,973,868 JBrowse link
positive regulation of alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101968779 HLA class II histocompatibility antigen, DQ beta 1 chain-like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:361,446...368,507 JBrowse link
positive regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (MGI:3620422|PMID:12163459), (MGI:3690682|PMID:11067867), (MGI:3774231|PMID:16670300)
(MGI:3690682|PMID:11067867), (MGI:3774231|PMID:16670300)
MGI PMID:11067867 PMID:12163459 PMID:16670300 MGI:3620422 MGI:3690682 MGI:3774231 NCBI chrNW_004936530:2,217,713...2,224,070 JBrowse link
G Gli3 GLI family zinc finger 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936478:17,129,922...17,403,630 JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936569:1,474,693...1,480,562 JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3039326|PMID:15064401) MGI
Ensembl
PMID:15064401 GO_REF:0000107 MGI:3039326 NCBI chrNW_004936526:3,378,046...3,477,177 JBrowse link
G LOC101971458 tyrosine-protein kinase ZAP-70 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:75253|PMID:7630421)
(MGI:893249|PMID:9208839)
(MGI:1096306|PMID:9275205)
MGI
Ensembl
PMID:7630421 PMID:9208839 PMID:9275205 GO_REF:0000107 MGI:1096306 MGI:75253 MGI:893249 NCBI chrNW_004936744:1,000,105...1,012,712 JBrowse link
G Nkap NFKB activating protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936479:10,024,674...10,041,738 JBrowse link
G Pnp purine nucleoside phosphorylase acts_upstream_of_or_within ISO (PMID:16964310) MGI PMID:16964310 NCBI chrNW_004936877:686,539...692,832 JBrowse link
G Rhoa ras homolog family member A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936529:1,000,050...1,045,655 JBrowse link
G Shh sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936527:10,033,095...10,042,713 JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1096306|PMID:9275205) MGI
Ensembl
PMID:9275205 GO_REF:0000107 MGI:1096306 NCBI chrNW_004936780:1,553,605...1,601,036 JBrowse link
positive regulation of alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO (MGI:3700903|PMID:17210642) MGI PMID:17210642 MGI:3700903 NCBI chrNW_004936483:16,194,092...16,295,803 JBrowse link
G Cd80 CD80 molecule acts_upstream_of_or_within ISO (MGI:3757624|PMID:1385153) MGI PMID:1385153 MGI:3757624 NCBI chrNW_004936536:6,462,080...6,483,450 JBrowse link
G LOC101964770 C-C chemokine receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936596:285,559...287,198 JBrowse link
G LOC101968601 signal transducer CD24 acts_upstream_of_or_within ISO (MGI:3757622|PMID:7908303), (MGI:3757624|PMID:1385153)
(MGI:3757614|PMID:9368605), (MGI:3757626|PMID:1346270)
MGI PMID:1346270 PMID:1385153 PMID:7908303 PMID:9368605 MGI:3757614 MGI:3757622 MGI:3757624 MGI:3757626 NCBI chrNW_004936491:16,706,745...16,707,010 JBrowse link
G LOC101971458 tyrosine-protein kinase ZAP-70 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1096306|PMID:9275205) MGI
Ensembl
PMID:9275205 GO_REF:0000107 MGI:1096306 NCBI chrNW_004936744:1,000,105...1,012,712 JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:73253|PMID:7751624) MGI
Ensembl
PMID:7751624 GO_REF:0000107 MGI:73253 NCBI chrNW_004936567:5,266,653...5,378,464 JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1096306|PMID:9275205) MGI
Ensembl
PMID:9275205 GO_REF:0000107 MGI:1096306 NCBI chrNW_004936780:1,553,605...1,601,036 JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3772919|PMID:16670306) BHF-UCL PMID:16670306 MGI:3772919 NCBI chrNW_004936481:14,391,359...14,409,514 JBrowse link
positive regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) UniProt PMID:16818763 NCBI chrNW_004936557:5,344,373...5,364,234 JBrowse link
G LOC101954488 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:5451119|PMID:23123061) MGI PMID:23123061 MGI:5451119 NCBI chrNW_004936706:37,480...53,306 JBrowse link
G LOC101969065 mamu class II histocompatibility antigen, DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:540,225...544,968 JBrowse link
positive regulation of CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4819294|PMID:20639485) BHF-UCL PMID:20639485 MGI:4819294 NCBI chrNW_004936481:14,391,359...14,409,514 JBrowse link
positive regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd83 CD83 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3054335|PMID:15322158) MGI
Ensembl
PMID:15322158 GO_REF:0000107 MGI:3054335 NCBI chrNW_004936552:637,471...654,422 JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3697020|PMID:17028180) MGI
Ensembl
PMID:17028180 GO_REF:0000107 MGI:3697020 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Nckap1l NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936512:11,683,330...11,734,423 JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3607020|PMID:16227612) MGI
Ensembl
PMID:16227612 GO_REF:0000107 MGI:3607020 NCBI chrNW_004936479:1,752,180...1,765,330 JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936530:9,312,965...9,315,593 JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4819294|PMID:20639485) BHF-UCL PMID:20639485 MGI:4819294 NCBI chrNW_004936481:14,391,359...14,409,514 JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:4,546,139...4,560,157 JBrowse link
positive regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card11 caspase recruitment domain family member 11 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3039643|PMID:12867038) MGI
Ensembl
PMID:12867038 GO_REF:0000107 MGI:3039643 NCBI chrNW_004936823:580,438...621,298 JBrowse link
G Cd28 CD28 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3038342|PMID:14973438), (MGI:3757614|PMID:9368605), (MGI:65397|PMID:8125140)
(MGI:3757614|PMID:9368605)
MGI
Ensembl
PMID:8125140 PMID:9368605 PMID:14973438 GO_REF:0000107 MGI:3038342 MGI:3757614 MGI:65397 NCBI chrNW_004936631:335,411...363,407 JBrowse link
G Cd3e CD3e molecule acts_upstream_of_or_within ISO (MGI:2176424|PMID:11894097), (MGI:3038342|PMID:14973438), (MGI:65397|PMID:8125140) MGI PMID:8125140 PMID:11894097 PMID:14973438 MGI:2176424 MGI:3038342 MGI:65397 NCBI chrNW_004936542:3,379,361...3,390,677 JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) UniProt PMID:16818763 NCBI chrNW_004936557:5,344,373...5,364,234 JBrowse link
G Cd81 CD81 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936794:664,089...670,294 JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:16116184) UniProt PMID:16116184 NCBI chrNW_004936538:4,034,467...4,050,240 JBrowse link
G LOC101954488 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:5451119|PMID:23123061) MGI PMID:23123061 MGI:5451119 NCBI chrNW_004936706:37,480...53,306 JBrowse link
G LOC101968601 signal transducer CD24 acts_upstream_of_or_within ISO (MGI:3510282|PMID:15314074)
(MGI:65397|PMID:8125140)
MGI PMID:8125140 PMID:15314074 MGI:3510282 MGI:65397 NCBI chrNW_004936491:16,706,745...16,707,010 JBrowse link
G LOC101970885 lymphotactin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936481:17,825,714...17,828,955 JBrowse link
G Prkcq protein kinase C theta acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3039643|PMID:12867038) MGI
Ensembl
PMID:12867038 GO_REF:0000107 MGI:3039643 NCBI chrNW_004936484:8,048,239...8,166,058 JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2176422|PMID:11894098)
(MGI:2176424|PMID:11894097)
MGI
Ensembl
PMID:11894097 PMID:11894098 GO_REF:0000107 MGI:2176422 MGI:2176424 NCBI chrNW_004936544:3,606,925...3,653,248 JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:21,324,669...21,409,430 JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3695768|PMID:16275384)
(MGI:2653673|PMID:12612578)
(MGI:3700459|PMID:16301745), (MGI:3799419|PMID:18573908)
MGI
Ensembl
PMID:12612578 PMID:16275384 PMID:16301745 PMID:18573908 GO_REF:0000107 MGI:2653673 MGI:3695768 MGI:3700459 MGI:3799419 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3662823|PMID:16227984) MGI
Ensembl
PMID:16227984 GO_REF:0000107 MGI:3662823 NCBI chrNW_004936762:487,414...491,028 JBrowse link
G Klhl25 kelch like family member 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936483:12,001,111...12,033,158 JBrowse link
G LOC101969065 mamu class II histocompatibility antigen, DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:540,225...544,968 JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:20209097) UniProt PMID:20209097 NCBI chrNW_004936538:4,034,467...4,050,240 JBrowse link
positive regulation of CD8-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101954488 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:5451119|PMID:23123061) MGI PMID:23123061 MGI:5451119 NCBI chrNW_004936706:37,480...53,306 JBrowse link
positive regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbfb core-binding factor subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:17,537,273...17,589,383 JBrowse link
G Nckap1l NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936512:11,683,330...11,734,423 JBrowse link
G Runx3 RUNX family transcription factor 3 involved_in ISO (MGI:3772948|PMID:18258917) UniProt PMID:18258917 MGI:3772948 NCBI chrNW_004936474:9,751,946...9,802,910 JBrowse link
positive regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO (MGI:5700312|PMID:11739483) UniProt PMID:11739483 MGI:5700312 NCBI chrNW_004936903:146,108...162,410 JBrowse link
G LOC101970885 lymphotactin involved_in ISO (PMID:10887101) BHF-UCL PMID:10887101 NCBI chrNW_004936481:17,825,714...17,828,955 JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936690:2,180,804...2,232,869 JBrowse link
positive regulation of NK T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il12a interleukin 12A involved_in ISO (PMID:19088061) BHF-UCL PMID:19088061 NCBI chrNW_004936519:6,166,060...6,180,652 JBrowse link
G Il12b interleukin 12B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936515:4,056,214...4,066,121 JBrowse link
G Il23a interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936646:743,630...745,998 JBrowse link
positive regulation of NK T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3b1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2679144|PMID:14557411) MGI
Ensembl
PMID:14557411 GO_REF:0000107 MGI:2679144 NCBI chrNW_004936549:5,964,240...6,205,245 JBrowse link
G Ap3d1 adaptor related protein complex 3 subunit delta 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2679144|PMID:14557411) MGI
Ensembl
PMID:14557411 GO_REF:0000107 MGI:2679144 NCBI chrNW_004936588:1,223,646...1,262,577 JBrowse link
G Ikzf1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (MGI:1340364|PMID:10366784) MGI PMID:10366784 MGI:1340364 NCBI chrNW_004936686:1,459,582...1,556,478 JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3686949|PMID:16973387) MGI
Ensembl
PMID:16973387 GO_REF:0000107 MGI:3686949 NCBI chrNW_004936473:21,324,669...21,409,430 JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936612:389,877...570,595 JBrowse link
positive regulation of NK T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il12a interleukin 12A involved_in ISO (PMID:19088061) ComplexPortal PMID:19088061 NCBI chrNW_004936519:6,166,060...6,180,652 JBrowse link
G Il12b interleukin 12B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936515:4,056,214...4,066,121 JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 involved_in ISO (PMID:19088061) ComplexPortal PMID:19088061 NCBI chrNW_004936596:3,062,620...3,076,349 JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 involved_in ISO (PMID:19088061) ComplexPortal PMID:19088061 NCBI chrNW_004936591:4,238,720...4,310,847 JBrowse link
G Il18 interleukin 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936612:2,306,963...2,325,086 JBrowse link
G Il23a interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936646:743,630...745,998 JBrowse link
G Jak2 Janus kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936503:111,722...243,627 JBrowse link
G Rasal3 RAS protein activator like 3 involved_in ISO (PMID:25652366) UniProt PMID:25652366 NCBI chrNW_004936596:5,048,068...5,059,074 JBrowse link
G Tyk2 tyrosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936659:681,463...704,484 JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936503:9,124,314...9,142,372 JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (MGI:3576832|PMID:15845453) BHF-UCL PMID:15845453 MGI:3576832 NCBI chrNW_004936524:2,765,271...2,767,259 JBrowse link
G Hlx H2.0 like homeobox acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3761239|PMID:16424184) MGI
Ensembl
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chrNW_004936650:1,416,825...1,422,595 JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2176424|PMID:11894097) MGI
Ensembl
PMID:11894097 GO_REF:0000107 MGI:2176424 NCBI chrNW_004936544:3,606,925...3,653,248 JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936508:5,531,002...5,588,022 JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Malt1 MALT1 paracaspase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:5,854,361...5,910,719 JBrowse link
G Nfkbid NFKB inhibitor delta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004936570:464,513...471,333 JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936630:1,601,006...1,633,844 JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936864:709,693...732,119 JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il23a interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936646:743,630...745,998 JBrowse link
positive regulation of T-helper 2 cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcq protein kinase C theta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936484:8,048,239...8,166,058 JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) BHF-UCL PMID:12496423 MGI:3763508 NCBI chrNW_004936481:14,391,359...14,409,514 JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il18 interleukin 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936612:2,306,963...2,325,086 JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO (MGI:3761239|PMID:16424184) MGI PMID:16424184 MGI:3761239 NCBI chrNW_004936501:11,025,590...11,058,807 JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within ISO (MGI:2450484|PMID:12594267) MGI PMID:12594267 MGI:2450484 NCBI chrNW_004936549:7,015,595...7,016,246 JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936864:709,693...732,119 JBrowse link
G Prkcz protein kinase C zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936737:1,303,502...1,383,135 JBrowse link
G Rara retinoic acid receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:15,376,217...15,420,638 JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:4943387|PMID:18354165) BHF-UCL PMID:18354165 MGI:4943387 NCBI chrNW_004936481:14,391,359...14,409,514 JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myb MYB proto-oncogene, transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936560:2,797,943...2,828,813 JBrowse link
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5617929|PMID:24645804) MGI
Ensembl
PMID:24645804 GO_REF:0000107 MGI:5617929 NCBI chrNW_004936524:5,698,101...5,832,801 JBrowse link
regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankle1 ankyrin repeat and LEM domain containing 1 NOT|involved_in ISO (MGI:5800654|PMID:27010503) UniProt PMID:27010503 MGI:5800654 NCBI chrNW_004936596:3,568,810...3,573,506 JBrowse link
regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end-product specific receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:1,418,342...1,422,005 JBrowse link
regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sh3rf1 SH3 domain containing ring finger 1 involved_in ISO (MGI:6158776|PMID:27084103) UniProt PMID:27084103 MGI:6158776 NCBI chrNW_004936516:1,267,128...1,429,040 JBrowse link
regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il2 interleukin 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3662823|PMID:16227984) MGI
Ensembl
PMID:16227984 GO_REF:0000107 MGI:3662823 NCBI chrNW_004936662:1,594,953...1,599,625 JBrowse link
G Il2ra interleukin 2 receptor subunit alpha acts_upstream_of_or_within ISO (MGI:3662823|PMID:16227984) MGI PMID:16227984 MGI:3662823 NCBI chrNW_004936484:8,514,333...8,555,392 JBrowse link
regulation of CD8-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO (MGI:4359960|PMID:19752223) UniProt PMID:19752223 MGI:4359960 NCBI chrNW_004936542:7,402,879...7,411,510 JBrowse link
regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3817343|PMID:18776904) MGI
Ensembl
PMID:18776904 GO_REF:0000107 MGI:3817343 NCBI chrNW_004936580:4,546,139...4,560,157 JBrowse link
regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf1 interferon regulatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936647:2,686,247...2,693,633 JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936562:3,113,217...3,122,794 JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in ISO (MGI:5546548|PMID:23963642) UniProt PMID:23963642 MGI:5546548 NCBI chrNW_004936516:1,267,128...1,429,040 JBrowse link
regulation of NK T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prdm1 PR/SET domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936564:2,594,362...2,690,680 JBrowse link
G Znf683 zinc finger protein 683 involved_in ISO (MGI:5779429|PMID:27102484) UniProt PMID:27102484 MGI:5779429 NCBI chrNW_004936474:10,851,249...10,859,092 JBrowse link
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il27 interleukin 27 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:11,972,715...11,978,152 JBrowse link
regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl20 C-C motif chemokine ligand 20 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chrNW_004936525:8,238,128...8,240,974 JBrowse link
G Ccr6 C-C motif chemokine receptor 6 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chrNW_004936489:16,669,297...16,689,451 JBrowse link
regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata3 GATA binding protein 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3817343|PMID:18776904) MGI
Ensembl
PMID:18776904 GO_REF:0000107 MGI:3817343 NCBI chrNW_004936484:6,780,692...6,800,883 JBrowse link
G LOC101969065 mamu class II histocompatibility antigen, DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:540,225...544,968 JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3817343|PMID:18776904) MGI
Ensembl
PMID:18776904 GO_REF:0000107 MGI:3817343 NCBI chrNW_004936580:4,546,139...4,560,157 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15040
    regulation of biological process 10217
      regulation of immune system process 1296
        regulation of leukocyte activation 553
          regulation of lymphocyte activation 454
            regulation of T cell activation 326
              regulation of alpha-beta T cell activation 106
                negative regulation of alpha-beta T cell activation + 38
                positive regulation of alpha-beta T cell activation + 70
                regulation of CD4-positive, alpha-beta T cell activation + 68
                regulation of CD8-positive, alpha-beta T cell activation + 15
                regulation of NK T cell activation + 10
                regulation of alpha-beta T cell differentiation + 65
                regulation of alpha-beta T cell proliferation + 47
Path 2
Term Annotations click to browse term
  biological_process 15040
    biological regulation 10787
      regulation of biological process 10217
        regulation of cellular process 9652
          regulation of cell activation 604
            regulation of leukocyte activation 553
              regulation of lymphocyte activation 454
                regulation of T cell activation 326
                  regulation of alpha-beta T cell activation 106
                    negative regulation of alpha-beta T cell activation + 38
                    positive regulation of alpha-beta T cell activation + 70
                    regulation of CD4-positive, alpha-beta T cell activation + 68
                    regulation of CD8-positive, alpha-beta T cell activation + 15
                    regulation of NK T cell activation + 10
                    regulation of alpha-beta T cell differentiation + 65
                    regulation of alpha-beta T cell proliferation + 47
paths to the root