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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of alpha-beta T cell activation
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Accession:GO:0046634 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of alpha-beta T cell activation.
Synonyms:exact_synonym: regulation of alpha-beta T lymphocyte activation



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CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD81 CD81 molecule involved_in IDA (PMID:22307619) UniProt
UniProt
PMID:22307619 NCBI chr11:2,376,180...2,397,397
Ensembl chr11:2,376,177...2,397,802
JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:4819294|PMID:20639485) BHF-UCL PMID:20639485 MGI:4819294 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331
JBrowse link
negative regulation of alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3822045|PMID:10069416) MGI
Ensembl
Ensembl
PMID:10069416 GO_REF:0000107 MGI:3822045 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357
JBrowse link
G LILRB1 leukocyte immunoglobulin like receptor B1 involved_in IDA (PMID:21213105) UniProt
UniProt
PMID:21213105 NCBI chr19:54,616,322...54,638,022
Ensembl chr19:54,617,158...54,638,022
JBrowse link
G VSIR V-set immunoregulatory receptor involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:71,747,556...71,773,520
Ensembl chr10:71,747,556...71,773,520
JBrowse link
negative regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI3 GLI family zinc finger 3 involved_in ISS
IEA
BHF-UCL
BHF-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:41,960,949...42,264,268
Ensembl chr 7:41,960,949...42,264,100
JBrowse link
G IHH Indian hedgehog signaling molecule involved_in ISS
IEA
BHF-UCL
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:219,054,424...219,060,921
Ensembl chr 2:219,054,424...219,060,921
JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1888832|PMID:10981962) Ensembl
Ensembl
MGI
PMID:10981962 GO_REF:0000107 MGI:1888832 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463
JBrowse link
negative regulation of alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTLA B and T lymphocyte associated acts_upstream_of_or_within ISO (MGI:3521631|PMID:15568026) MGI PMID:15568026 MGI:3521631 NCBI chr 3:112,463,966...112,499,624
Ensembl chr 3:112,463,966...112,499,472
JBrowse link
G CBLB Cbl proto-oncogene B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:105,655,461...105,869,449
Ensembl chr 3:105,655,461...105,869,552
JBrowse link
G CLEC4G C-type lectin domain family 4 member G acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5475030|PMID:23487419) MGI
Ensembl
PMID:23487419 GO_REF:0000107 MGI:5475030 NCBI chr19:7,728,957...7,732,110
Ensembl chr19:7,728,957...7,733,906
JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3692513|PMID:16945588) MGI
Ensembl
PMID:16945588 GO_REF:0000107 MGI:3692513 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,270,477
JBrowse link
G ITCH itchy E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,235...34,511,773
JBrowse link
G TNFRSF14 TNF receptor superfamily member 14 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 1:2,554,234...2,563,829
Ensembl chr 1:2,555,639...2,565,382
JBrowse link
negative regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TARM1 T cell-interacting, activating receptor on myeloid cells 1 involved_in IDA (PMID:26311901) UniProt
UniProt
PMID:26311901 NCBI chr19:54,069,895...54,081,365
Ensembl chr19:54,069,895...54,081,365
JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 involved_in IDA (PMID:17164348) BHF-UCL
BHF-UCL
PMID:17164348 NCBI chr18:9,334,773...9,402,420
Ensembl chr18:9,334,767...9,402,420
JBrowse link
negative regulation of CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD160 CD160 molecule involved_in IDA (PMID:18193050) UniProt
UniProt
PMID:18193050 NCBI chr 1:145,719,499...145,739,288
Ensembl chr 1:145,719,471...145,739,288
JBrowse link
negative regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBFB core-binding factor subunit beta involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr16:67,029,149...67,101,058
Ensembl chr16:67,028,984...67,101,058
JBrowse link
G HMGB1 high mobility group box 1 involved_in IDA (PMID:22473704) UniProt
UniProt
PMID:22473704 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
JBrowse link
G RUNX1 RUNX family transcription factor 1 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G RUNX3 RUNX family transcription factor 3 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121
JBrowse link
negative regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARG2 arginase 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708
JBrowse link
G CBLB Cbl proto-oncogene B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3038342|PMID:14973438) MGI
Ensembl
PMID:14973438 GO_REF:0000107 MGI:3038342 NCBI chr 3:105,655,461...105,869,449
Ensembl chr 3:105,655,461...105,869,552
JBrowse link
G CD274 CD274 molecule involved_in IDA (PMID:24691993) UniProt
UniProt
PMID:24691993 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566
JBrowse link
G CD44 CD44 molecule (Indian blood group) involved_in ISO (MGI:5688819|PMID:25065622) UniProt PMID:25065622 MGI:5688819 NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3697020|PMID:17028180) MGI
Ensembl
PMID:17028180 GO_REF:0000107 MGI:3697020 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,270,477
JBrowse link
G ITCH itchy E3 ubiquitin protein ligase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3038342|PMID:14973438) MGI
Ensembl
PMID:14973438 GO_REF:0000107 MGI:3038342 NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,235...34,511,773
JBrowse link
G LGALS7 galectin 7 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr19:38,770,968...38,773,517
Ensembl chr19:38,789,200...38,791,754
Ensembl chr19:38,789,200...38,791,754
JBrowse link
G LGALS7B galectin 7B involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr19:38,789,200...38,791,754
Ensembl chr19:38,789,200...38,791,754
Ensembl chr19:38,789,200...38,791,754
JBrowse link
G LGALS9 galectin 9 involved_in IDA
IBA
(PMID:20209097)
(PMID:21873635)
UniProt
UniProt
GO_Central
GO_Central
PMID:20209097 PMID:21873635 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560
JBrowse link
G LGALS9B galectin 9B involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr17:20,449,395...20,467,539
Ensembl chr17:20,449,395...20,467,539
JBrowse link
G LGALS9C galectin 9C involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr17:18,476,789...18,494,945
Ensembl chr17:18,476,737...18,494,945
JBrowse link
G NDFIP1 Nedd4 family interacting protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3694584|PMID:17137798) MGI
Ensembl
PMID:17137798 GO_REF:0000107 MGI:3694584 NCBI chr 5:142,108,779...142,154,440
Ensembl chr 5:142,108,779...142,154,440
JBrowse link
G TARM1 T cell-interacting, activating receptor on myeloid cells 1 involved_in ISO (MGI:5908526|PMID:26311901) UniProt PMID:26311901 MGI:5908526 NCBI chr19:54,069,895...54,081,365
Ensembl chr19:54,069,895...54,081,365
JBrowse link
G TNFRSF14 TNF receptor superfamily member 14 acts_upstream_of_or_within ISO (MGI:3521631|PMID:15568026) MGI PMID:15568026 MGI:3521631 NCBI chr 1:2,554,234...2,563,829
Ensembl chr 1:2,555,639...2,565,382
JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 involved_in IDA (PMID:17164348) BHF-UCL
BHF-UCL
PMID:17164348 NCBI chr18:9,334,773...9,402,420
Ensembl chr18:9,334,767...9,402,420
JBrowse link
G VSIR V-set immunoregulatory receptor involved_in
acts_upstream_of_or_within
IMP
ISO
(PMID:24691993)
(MGI:5292805|PMID:21383057)
UniProt
UniProt
MGI
PMID:21383057 PMID:24691993 MGI:5292805 NCBI chr10:71,747,556...71,773,520
Ensembl chr10:71,747,556...71,773,520
JBrowse link
G XCL1 X-C motif chemokine ligand 1 involved_in IDA (PMID:10887101) BHF-UCL
BHF-UCL
PMID:10887101 NCBI chr 1:168,576,605...168,582,069
Ensembl chr 1:168,576,605...168,582,069
JBrowse link
negative regulation of CD8-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD274 CD274 molecule involved_in IMP (PMID:28813410), (PMID:28813417) UniProt
UniProt
PMID:28813410 PMID:28813417 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566
JBrowse link
G HFE homeostatic iron regulator involved_in IGI (PMID:24643698) BHF-UCL
BHF-UCL
PMID:24643698 NCBI chr 6:26,087,429...26,098,343
Ensembl chr 6:26,087,281...26,098,343
JBrowse link
G LILRB1 leukocyte immunoglobulin like receptor B1 involved_in IDA (PMID:21213105) UniProt
UniProt
PMID:21213105 NCBI chr19:54,616,322...54,638,022
Ensembl chr19:54,617,158...54,638,022
JBrowse link
negative regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SOCS1 suppressor of cytokine signaling 1 involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204
JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:155,001,750...155,018,523
Ensembl chr 1:155,002,630...155,018,523
JBrowse link
negative regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VSIR V-set immunoregulatory receptor involved_in IMP (PMID:24691993) UniProt
UniProt
PMID:24691993 NCBI chr10:71,747,556...71,773,520
Ensembl chr10:71,747,556...71,773,520
JBrowse link
negative regulation of NK T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD300A CD300a molecule involved_in IDA (PMID:10540326) UniProt
UniProt
PMID:10540326 NCBI chr17:74,466,373...74,484,798
Ensembl chr17:74,466,399...74,484,794
JBrowse link
negative regulation of NK T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZBTB7B zinc finger and BTB domain containing 7B involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:155,001,750...155,018,523
Ensembl chr 1:155,002,630...155,018,523
JBrowse link
negative regulation of T-helper 1 cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G XCL1 X-C motif chemokine ligand 1 involved_in IDA (PMID:10887101) BHF-UCL
BHF-UCL
PMID:10887101 NCBI chr 1:168,576,605...168,582,069
Ensembl chr 1:168,576,605...168,582,069
JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL4R interleukin 4 receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3761239|PMID:16424184) Ensembl
Ensembl
MGI
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G JAK3 Janus kinase 3 involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr19:17,824,782...17,847,982
Ensembl chr19:17,824,780...17,848,071
JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331
JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 involved_in IMP (PMID:23169781) UniProt
UniProt
PMID:23169781 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,270,477
JBrowse link
G IL2 interleukin 2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL4 interleukin 4 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:3817792|PMID:18792410)
GO_Central
GO_Central
MGI
PMID:18792410 PMID:21873635 MGI:3817792 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:173,931,084...174,022,357
Ensembl chr 1:173,931,084...174,022,357
JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 9:122,844,556...122,905,359
Ensembl chr 9:122,844,556...122,905,359
JBrowse link
G SMAD7 SMAD family member 7 involved_in ISS
IEA
BHF-UCL
BHF-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr18:48,919,853...48,950,965
Ensembl chr18:48,919,853...48,950,965
JBrowse link
G TBX21 T-box transcription factor 21 involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122
JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5450776|PMID:23034280) Ensembl
Ensembl
MGI
PMID:23034280 GO_REF:0000107 MGI:5450776 NCBI chr 1:155,001,750...155,018,523
Ensembl chr 1:155,002,630...155,018,523
JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:37,474,580...37,484,377
Ensembl chr 1:37,474,580...37,484,377
JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOXL3 lysyl oxidase like 3 involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:74,532,258...74,555,702
Ensembl chr 2:74,532,258...74,555,690
JBrowse link
G TBX21 T-box transcription factor 21 involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122
JBrowse link
G TNFSF18 TNF superfamily member 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:173,039,202...173,050,941
Ensembl chr 1:173,039,202...173,050,941
JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IBA
IDA
(PMID:21873635)
(PMID:17008549)
GO_Central
UniProt
GO_Central
UniProt
PMID:17008549 PMID:21873635 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
JBrowse link
G BCL6 BCL6 transcription repressor involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2450484|PMID:12594267) Ensembl
Ensembl
MGI
PMID:12594267 GO_REF:0000107 MGI:2450484 NCBI chr 3:187,721,377...187,745,468
Ensembl chr 3:187,721,377...187,745,725
JBrowse link
G HLX H2.0 like homeobox involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3761239|PMID:16424184) Ensembl
Ensembl
MGI
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chr 1:220,879,443...220,885,059
Ensembl chr 1:220,879,431...220,885,059
JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:46,698,937...46,763,129
Ensembl chr 2:46,698,952...46,780,245
JBrowse link
G ZNF271P zinc finger protein 271, pseudogene acts_upstream_of_or_within ISO (MGI:4366385|PMID:19783676) MGI PMID:19783676 MGI:4366385 NCBI chr18:35,290,272...35,310,766
Ensembl chr18:35,290,276...35,328,390
JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RC3H1 ring finger and CCCH-type domains 1 involved_in
acts_upstream_of_or_within
ISS
IEA
ISO
(MGI:3580753|PMID:15917799) BHF-UCL
Ensembl
BHF-UCL
MGI
PMID:15917799 GO_REF:0000024 GO_REF:0000107 MGI:3580753 NCBI chr 1:173,931,084...174,022,357
Ensembl chr 1:173,931,084...174,022,357
JBrowse link
positive regulation of alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 involved_in ISO (MGI:4942246|PMID:14607905)
(MGI:4943670|PMID:9610637)
BHF-UCL PMID:9610637 PMID:14607905 MGI:4942246 MGI:4943670 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
JBrowse link
positive regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3620422|PMID:12163459), (MGI:3690682|PMID:11067867), (MGI:3774231|PMID:16670300)
(MGI:3690682|PMID:11067867), (MGI:3774231|PMID:16670300)
Ensembl
Ensembl
MGI
PMID:11067867 PMID:12163459 PMID:16670300 GO_REF:0000107 MGI:3620422 MGI:3690682 MGI:3774231 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252
JBrowse link
G GLI3 GLI family zinc finger 3 involved_in ISS
IEA
BHF-UCL
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:41,960,949...42,264,268
Ensembl chr 7:41,960,949...42,264,100
JBrowse link
G IHH Indian hedgehog signaling molecule involved_in ISS
IEA
BHF-UCL
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:219,054,424...219,060,921
Ensembl chr 2:219,054,424...219,060,921
JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3039326|PMID:15064401) Ensembl
Ensembl
MGI
PMID:15064401 GO_REF:0000107 MGI:3039326 NCBI chr 1:226,631,690...226,739,282
Ensembl chr 1:226,631,690...226,739,323
JBrowse link
G NKAP NFKB activating protein involved_in IMP (PMID:19409814) UniProt
UniProt
PMID:19409814 NCBI chr  X:119,920,672...119,943,751
Ensembl chr  X:119,920,672...119,943,751
JBrowse link
G PNP purine nucleoside phosphorylase acts_upstream_of_or_within IDA (PMID:16964310) MGI
MGI
PMID:16964310 NCBI chr14:20,469,406...20,477,089
Ensembl chr14:20,461,992...20,477,094
JBrowse link
G RHOA ras homolog family member A involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998
JBrowse link
G SHH sonic hedgehog signaling molecule involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463
JBrowse link
G SYK spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1096306|PMID:9275205) Ensembl
Ensembl
MGI
PMID:9275205 GO_REF:0000107 MGI:1096306 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549
JBrowse link
G ZAP70 zeta chain of T cell receptor associated protein kinase 70 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:75253|PMID:7630421)
(MGI:1096306|PMID:9275205)
(MGI:893249|PMID:9208839)
Ensembl
Ensembl
MGI
PMID:7630421 PMID:9208839 PMID:9275205 GO_REF:0000107 MGI:1096306 MGI:75253 MGI:893249 NCBI chr 2:97,713,576...97,756,364
Ensembl chr 2:97,713,576...97,739,862
JBrowse link
positive regulation of alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLM BLM RecQ like helicase acts_upstream_of_or_within ISO (MGI:3700903|PMID:17210642) MGI PMID:17210642 MGI:3700903 NCBI chr15:90,717,346...90,816,166
Ensembl chr15:90,717,346...90,816,166
JBrowse link
G CCR2 C-C motif chemokine receptor 2 involved_in ISS
IEA
BHF-UCL
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
JBrowse link
G CD24 CD24 molecule acts_upstream_of_or_within ISO (MGI:3757622|PMID:7908303), (MGI:3757624|PMID:1385153)
(MGI:3757614|PMID:9368605)
(MGI:3757614|PMID:9368605), (MGI:3757626|PMID:1346270)
MGI PMID:1346270 PMID:1385153 PMID:7908303 PMID:9368605 MGI:3757614 MGI:3757622 MGI:3757624 MGI:3757626 NCBI chr 6:106,969,831...106,976,855
Ensembl chr 6:106,969,831...106,975,627
JBrowse link
G CD28 CD28 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:203,706,465...203,738,912
Ensembl chr 2:203,706,475...203,738,912
JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:118,304,730...118,316,173
Ensembl chr11:118,304,730...118,316,175
JBrowse link
G CD80 CD80 molecule acts_upstream_of_or_within ISO (MGI:3757624|PMID:1385153) MGI PMID:1385153 MGI:3757624 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614
JBrowse link
G EBI3 Epstein-Barr virus induced 3 involved_in TAS (PMID:14743498) UniProt
UniProt
PMID:14743498 NCBI chr19:4,229,523...4,237,528
Ensembl chr19:4,229,523...4,237,528
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:73253|PMID:7751624) Ensembl
Ensembl
MGI
PMID:7751624 GO_REF:0000107 MGI:73253 NCBI chr 1:198,638,713...198,757,476
Ensembl chr 1:198,638,457...198,757,476
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064
JBrowse link
G SYK spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:1096306|PMID:9275205)
GO_Central
Ensembl
GO_Central
MGI
PMID:9275205 PMID:21873635 GO_REF:0000107 MGI:1096306 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549
JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331
JBrowse link
G ZAP70 zeta chain of T cell receptor associated protein kinase 70 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:1096306|PMID:9275205) Ensembl
Ensembl
MGI
PMID:9275205 GO_REF:0000107 MGI:1096306 NCBI chr 2:97,713,576...97,756,364
Ensembl chr 2:97,713,576...97,739,862
JBrowse link
positive regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD55 CD55 molecule (Cromer blood group) involved_in IDA (PMID:16818763) UniProt
UniProt
PMID:16818763 NCBI chr 1:207,321,678...207,360,966
Ensembl chr 1:207,321,519...207,386,804
JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:5451119|PMID:23123061) MGI PMID:23123061 MGI:5451119 NCBI chr19:42,507,306...42,528,481
Ensembl chr19:42,507,304...42,561,234
JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha involved_in IDA (PMID:15265931) UniProt
UniProt
PMID:15265931 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 involved_in IDA (PMID:15265931) UniProt
UniProt
PMID:15265931 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848
JBrowse link
G HLA-DRB3 major histocompatibility complex, class II, DR beta 3 involved_in IDA (PMID:19531622) UniProt
UniProt
PMID:19531622
positive regulation of CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFSF4 TNF superfamily member 4 involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331
JBrowse link
positive regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD83 CD83 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3054335|PMID:15322158) Ensembl
Ensembl
MGI
PMID:15322158 GO_REF:0000107 MGI:3054335 NCBI chr 6:14,117,256...14,136,918
Ensembl chr 6:14,117,256...14,136,918
JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3697020|PMID:17028180) MGI
Ensembl
PMID:17028180 GO_REF:0000107 MGI:3697020 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,270,477
JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr12:54,497,752...54,548,243
Ensembl chr12:54,497,752...54,548,243
JBrowse link
G SASH3 SAM and SH3 domain containing 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3607020|PMID:16227612) Ensembl
Ensembl
MGI
PMID:16227612 GO_REF:0000107 MGI:3607020 NCBI chr  X:129,779,949...129,795,201
Ensembl chr  X:129,779,949...129,795,201
JBrowse link
G SOCS1 suppressor of cytokine signaling 1 involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204
JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331
JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:155,001,750...155,018,523
Ensembl chr 1:155,002,630...155,018,523
JBrowse link
positive regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARD11 caspase recruitment domain family member 11 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3039643|PMID:12867038) MGI
Ensembl
PMID:12867038 GO_REF:0000107 MGI:3039643 NCBI chr 7:2,906,142...3,043,867
Ensembl chr 7:2,906,142...3,044,228
JBrowse link
G CD24 CD24 molecule acts_upstream_of_or_within ISO (MGI:65397|PMID:8125140)
(MGI:3510282|PMID:15314074)
MGI PMID:8125140 PMID:15314074 MGI:3510282 MGI:65397 NCBI chr 6:106,969,831...106,976,855
Ensembl chr 6:106,969,831...106,975,627
JBrowse link
G CD28 CD28 molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3038342|PMID:14973438), (MGI:3757614|PMID:9368605), (MGI:65397|PMID:8125140)
(MGI:3757614|PMID:9368605)
MGI
Ensembl
PMID:8125140 PMID:9368605 PMID:14973438 GO_REF:0000107 MGI:3038342 MGI:3757614 MGI:65397 NCBI chr 2:203,706,465...203,738,912
Ensembl chr 2:203,706,475...203,738,912
JBrowse link
G CD3E CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2176424|PMID:11894097), (MGI:3038342|PMID:14973438), (MGI:65397|PMID:8125140) MGI
Ensembl
PMID:8125140 PMID:11894097 PMID:14973438 GO_REF:0000107 MGI:2176424 MGI:3038342 MGI:65397 NCBI chr11:118,304,730...118,316,173
Ensembl chr11:118,304,730...118,316,175
JBrowse link
G CD55 CD55 molecule (Cromer blood group) involved_in IDA (PMID:16818763) UniProt
UniProt
PMID:16818763 NCBI chr 1:207,321,678...207,360,966
Ensembl chr 1:207,321,519...207,386,804
JBrowse link
G CD81 CD81 molecule involved_in IDA (PMID:22307619) UniProt
UniProt
PMID:22307619 NCBI chr11:2,376,180...2,397,397
Ensembl chr11:2,376,177...2,397,802
JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:5451119|PMID:23123061) MGI PMID:23123061 MGI:5451119 NCBI chr19:42,507,306...42,528,481
Ensembl chr19:42,507,304...42,561,234
JBrowse link
G LGALS9 galectin 9 involved_in IDA (PMID:16116184) UniProt
UniProt
PMID:16116184 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560
JBrowse link
G PRKCQ protein kinase C theta acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3039643|PMID:12867038) MGI
Ensembl
PMID:12867038 GO_REF:0000107 MGI:3039643 NCBI chr10:6,394,097...6,580,646
Ensembl chr10:6,427,143...6,580,301
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2176424|PMID:11894097)
(MGI:2176422|PMID:11894098)
MGI
Ensembl
PMID:11894097 PMID:11894098 GO_REF:0000107 MGI:2176422 MGI:2176424 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in IDA (PMID:17164348) BHF-UCL
BHF-UCL
PMID:17164348 NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,601...30,694,142
JBrowse link
G XCL1 X-C motif chemokine ligand 1 involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr 1:168,576,605...168,582,069
Ensembl chr 1:168,576,605...168,582,069
JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 involved_in
acts_upstream_of_or_within
TAS
IEA
ISO
(PMID:18368049)
(MGI:3700459|PMID:16301745), (MGI:3799419|PMID:18573908)
(MGI:3695768|PMID:16275384)
(MGI:2653673|PMID:12612578)
UniProt
Ensembl
UniProt
MGI
PMID:12612578 PMID:16275384 PMID:16301745 PMID:18368049 PMID:18573908 GO_REF:0000107 MGI:2653673 MGI:3695768 MGI:3700459 MGI:3799419 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,270,477
JBrowse link
G GIMAP5 GTPase, IMAP family member 5 ISO RGD PMID:15778366 RGD:2303772 NCBI chr 7:150,737,418...150,743,646
Ensembl chr 7:150,722,253...150,750,033
JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha involved_in IDA (PMID:28467828) UniProt
UniProt
PMID:28467828 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 involved_in IDA (PMID:28467828) UniProt
UniProt
PMID:28467828 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848
JBrowse link
G IL2RG interleukin 2 receptor subunit gamma acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3662823|PMID:16227984) MGI
Ensembl
PMID:16227984 GO_REF:0000107 MGI:3662823 NCBI chr  X:71,107,404...71,111,577
Ensembl chr  X:71,107,404...71,112,108
JBrowse link
G KLHL25 kelch like family member 25 involved_in IEA
IDA
(PMID:34491895) Ensembl
UniProt
PMID:34491895 GO_REF:0000107 NCBI chr15:85,759,326...85,794,925
Ensembl chr15:85,759,326...85,794,925
JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in IDA (PMID:20209097) UniProt
UniProt
PMID:20209097 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G LGALS9 galectin 9 involved_in IDA (PMID:20209097) UniProt
UniProt
PMID:20209097 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560
JBrowse link
positive regulation of CD8-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEACAM1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:5451119|PMID:23123061) MGI PMID:23123061 MGI:5451119 NCBI chr19:42,507,306...42,528,481
Ensembl chr19:42,507,304...42,561,234
JBrowse link
G HLA-A major histocompatibility complex, class I, A involved_in IDA (PMID:24643698) BHF-UCL
BHF-UCL
PMID:24643698 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,945,884
JBrowse link
G HLA-E major histocompatibility complex, class I, E involved_in IDA (PMID:28676677) UniProt
UniProt
PMID:28676677 NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194
JBrowse link
positive regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBFB core-binding factor subunit beta involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr16:67,029,149...67,101,058
Ensembl chr16:67,028,984...67,101,058
JBrowse link
G LILRB4 leukocyte immunoglobulin like receptor B4 involved_in IDA (PMID:18420485) ARUK-UCL
ARUK-UCL
PMID:18420485 NCBI chr19:54,662,985...54,668,718
Ensembl chr19:54,643,889...54,670,359
JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr12:54,497,752...54,548,243
Ensembl chr12:54,497,752...54,548,243
JBrowse link
G RUNX1 RUNX family transcription factor 1 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667
JBrowse link
G RUNX3 RUNX family transcription factor 3 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr 1:24,899,511...24,965,138
Ensembl chr 1:24,899,511...24,965,121
JBrowse link
positive regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD244 CD244 molecule involved_in ISO (MGI:5700312|PMID:11739483) UniProt PMID:11739483 MGI:5700312 NCBI chr 1:160,830,160...160,862,887
Ensembl chr 1:160,830,160...160,862,887
JBrowse link
G HLA-A major histocompatibility complex, class I, A involved_in IDA (PMID:25631937) UniProt
UniProt
PMID:25631937 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,945,884
JBrowse link
G HLA-E major histocompatibility complex, class I, E involved_in IDA (PMID:25631937) UniProt
UniProt
PMID:25631937 NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA
IBA
(PMID:21873635) Ensembl
Ensembl
GO_Central
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 1:113,813,811...113,871,759
Ensembl chr 1:113,813,811...113,871,753
JBrowse link
G XCL1 X-C motif chemokine ligand 1 involved_in IDA (PMID:10887101) BHF-UCL
BHF-UCL
PMID:10887101 NCBI chr 1:168,576,605...168,582,069
Ensembl chr 1:168,576,605...168,582,069
JBrowse link
positive regulation of NK T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD1D CD1d molecule acts_upstream_of_or_within ISO (MGI:2180705|PMID:10201995), (MGI:3041278|PMID:11754812), (MGI:72888|PMID:7538697) MGI PMID:7538697 PMID:10201995 PMID:11754812 MGI:2180705 MGI:3041278 MGI:72888 NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427
JBrowse link
G HSPH1 heat shock protein family H (Hsp110) member 1 involved_in TAS (PMID:12952910) BHF-UCL
BHF-UCL
PMID:12952910 NCBI chr13:31,134,973...31,162,388
Ensembl chr13:31,134,973...31,162,388
JBrowse link
G IL12A interleukin 12A involved_in IDA (PMID:19088061) BHF-UCL
BHF-UCL
PMID:19088061 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019
JBrowse link
G IL12B interleukin 12B involved_in IC
IDA
(PMID:20027291)
(PMID:19088061)
BHF-UCL
BHF-UCL
PMID:19088061 PMID:20027291 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IC
IDA
(PMID:20027291)
(PMID:19088061)
BHF-UCL
BHF-UCL
PMID:19088061 PMID:20027291 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410
JBrowse link
G IL23R interleukin 23 receptor involved_in IC (PMID:19088061) BHF-UCL
BHF-UCL
PMID:19088061 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979
JBrowse link
positive regulation of NK T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP3B1 adaptor related protein complex 3 subunit beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2679144|PMID:14557411) Ensembl
Ensembl
MGI
PMID:14557411 GO_REF:0000107 MGI:2679144 NCBI chr 5:78,000,522...78,294,698
Ensembl chr 5:78,000,522...78,294,762
JBrowse link
G AP3D1 adaptor related protein complex 3 subunit delta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2679144|PMID:14557411) Ensembl
Ensembl
MGI
PMID:14557411 GO_REF:0000107 MGI:2679144 NCBI chr19:2,100,988...2,164,616
Ensembl chr19:2,100,988...2,164,468
JBrowse link
G CD1D CD1d molecule acts_upstream_of_or_within ISO (MGI:2180705|PMID:10201995)
(MGI:87097|PMID:9133426)
MGI PMID:9133426 PMID:10201995 MGI:2180705 MGI:87097 NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427
JBrowse link
G IKZF1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (MGI:1340364|PMID:10366784) MGI PMID:10366784 MGI:1340364 NCBI chr 7:50,303,455...50,405,101
Ensembl chr 7:50,304,068...50,405,101
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in
acts_upstream_of_or_within
ISS
IEA
ISO
(MGI:3686949|PMID:16973387) BHF-UCL
Ensembl
BHF-UCL
MGI
PMID:16973387 GO_REF:0000024 GO_REF:0000107 MGI:3686949 NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,601...30,694,142
JBrowse link
G ZBTB16 zinc finger and BTB domain containing 16 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr11:114,059,711...114,256,770
Ensembl chr11:114,059,041...114,256,765
JBrowse link
positive regulation of NK T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL12A interleukin 12A involved_in IDA (PMID:19088061) ComplexPortal
ComplexPortal
PMID:19088061 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019
JBrowse link
G IL12B interleukin 12B involved_in IDA
IC
(PMID:19088061) BHF-UCL
ComplexPortal
PMID:19088061 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
JBrowse link
G IL12RB1 interleukin 12 receptor subunit beta 1 involved_in IDA
IC
(PMID:19088061) ComplexPortal
ComplexPortal
PMID:19088061 NCBI chr19:18,058,995...18,098,816
Ensembl chr19:18,058,995...18,098,944
JBrowse link
G IL12RB2 interleukin 12 receptor subunit beta 2 involved_in IDA (PMID:19088061) ComplexPortal
ComplexPortal
PMID:19088061 NCBI chr 1:67,307,364...67,398,724
Ensembl chr 1:67,307,364...67,398,724
JBrowse link
G IL18 interleukin 18 involved_in IDA (PMID:19088061) BHF-UCL
BHF-UCL
PMID:19088061 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IDA
IC
(PMID:19088061) BHF-UCL
ComplexPortal
PMID:19088061 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410
JBrowse link
G IL23R interleukin 23 receptor involved_in IC (PMID:19088061) ComplexPortal PMID:19088061 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979
JBrowse link
G JAK2 Janus kinase 2 involved_in IDA
IC
(PMID:19088061) ComplexPortal
ComplexPortal
PMID:19088061 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
JBrowse link
G RASAL3 RAS protein activator like 3 involved_in IMP (PMID:25652366) UniProt
UniProt
PMID:25652366 NCBI chr19:15,451,624...15,464,544
Ensembl chr19:15,451,624...15,464,544
JBrowse link
G TYK2 tyrosine kinase 2 involved_in IDA
IC
(PMID:19088061) ComplexPortal
ComplexPortal
PMID:19088061 NCBI chr19:10,350,533...10,380,572
Ensembl chr19:10,350,533...10,380,608
JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IBA
IDA
(PMID:21873635)
(PMID:17008549)
GO_Central
UniProt
GO_Central
UniProt
PMID:17008549 PMID:21873635 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
JBrowse link
G CCL19 C-C motif chemokine ligand 19 involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276
JBrowse link
G CD80 CD80 molecule involved_in NAS (PMID:9915850) UniProt
UniProt
PMID:9915850 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614
JBrowse link
G HLX H2.0 like homeobox involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3761239|PMID:16424184) Ensembl
Ensembl
MGI
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chr 1:220,879,443...220,885,059
Ensembl chr 1:220,879,431...220,885,059
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2176424|PMID:11894097) Ensembl
Ensembl
MGI
PMID:11894097 GO_REF:0000107 MGI:2176424 NCBI chr 8:89,757,816...89,791,064
Ensembl chr 8:89,757,806...89,791,064
JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:46,698,937...46,763,129
Ensembl chr 2:46,698,952...46,780,245
JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MALT1 MALT1 paracaspase involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr18:58,671,465...58,754,477
Ensembl chr18:58,671,465...58,754,477
JBrowse link
G MIR21 microRNA 21 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337
JBrowse link
G MIR326 microRNA 326 acts_upstream_of_or_within ISO (MGI:4436838|PMID:19838199) MGI PMID:19838199 MGI:4436838 NCBI chr11:75,335,092...75,335,186
Ensembl chr11:75,335,092...75,335,186
JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr19:35,887,952...35,902,303
Ensembl chr19:35,887,653...35,902,303
JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108
JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL12B interleukin 12B involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
JBrowse link
G IL12RB1 interleukin 12 receptor subunit beta 1 involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr19:18,058,995...18,098,816
Ensembl chr19:18,058,995...18,098,944
JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IBA
ISS
IEA
(PMID:21873635) GO_Central
BHF-UCL
Ensembl
GO_Central
BHF-UCL
PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr12:56,338,884...56,340,410
Ensembl chr12:56,334,174...56,340,410
JBrowse link
G IL23R interleukin 23 receptor involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979
JBrowse link
positive regulation of T-helper 2 cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCQ protein kinase C theta involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr10:6,394,097...6,580,646
Ensembl chr10:6,427,143...6,580,301
JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) BHF-UCL PMID:12496423 MGI:3763508 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331
JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD86 CD86 molecule involved_in NAS (PMID:9915850) UniProt
UniProt
PMID:9915850 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
G IL18 interleukin 18 involved_in ISS
IEA
BHF-UCL
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL4R interleukin 4 receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3761239|PMID:16424184) Ensembl
Ensembl
MGI
PMID:16424184 GO_REF:0000107 MGI:3761239 NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G IL6 interleukin 6 acts_upstream_of_or_within ISO (MGI:2450484|PMID:12594267) MGI PMID:12594267 MGI:2450484 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISS
IEA
UniProt
UniProt
Ensembl
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108
JBrowse link
G PRKCZ protein kinase C zeta involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:2,048,504...2,185,395
Ensembl chr 1:2,050,411...2,185,395
JBrowse link
G RARA retinoic acid receptor alpha involved_in IDA (PMID:18416830) BHF-UCL
BHF-UCL
PMID:18416830 NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643
JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,183,731...173,207,331
JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYB MYB proto-oncogene, transcription factor involved_in IMP (PMID:20484083) UniProt
UniProt
PMID:20484083 NCBI chr 6:135,181,308...135,219,172
Ensembl chr 6:135,181,308...135,219,173
JBrowse link
G SHB SH2 domain containing adaptor protein B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5617929|PMID:24645804) MGI
Ensembl
PMID:24645804 GO_REF:0000107 MGI:5617929 NCBI chr 9:37,915,898...38,069,227
Ensembl chr 9:37,915,898...38,069,227
JBrowse link
regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKLE1 ankyrin repeat and LEM domain containing 1 NOT|involved_in ISO (MGI:5800654|PMID:27010503) UniProt PMID:27010503 MGI:5800654 NCBI chr19:17,281,901...17,287,646
Ensembl chr19:17,281,645...17,287,646
JBrowse link
regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor involved_in IDA (PMID:22473704) UniProt
UniProt
PMID:22473704 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA3 GATA binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198
JBrowse link
G SH3RF1 SH3 domain containing ring finger 1 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr 4:169,094,259...169,270,956
Ensembl chr 4:169,094,259...169,270,956
JBrowse link
regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL2 interleukin 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3662823|PMID:16227984) MGI
Ensembl
PMID:16227984 GO_REF:0000107 MGI:3662823 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3662823|PMID:16227984) MGI
Ensembl
PMID:16227984 GO_REF:0000107 MGI:3662823 NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370
JBrowse link
regulation of CD8-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRTAM cytotoxic and regulatory T cell molecule involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr11:122,838,500...122,872,643
Ensembl chr11:122,838,500...122,872,643
JBrowse link
regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZBTB7B zinc finger and BTB domain containing 7B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3817343|PMID:18776904) MGI
Ensembl
PMID:18776904 GO_REF:0000107 MGI:3817343 NCBI chr 1:155,001,750...155,018,523
Ensembl chr 1:155,002,630...155,018,523
JBrowse link
regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRF1 interferon regulatory factor 1 involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719
JBrowse link
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr11:45,885,651...45,906,465
Ensembl chr11:45,885,651...45,906,465
JBrowse link
G SH3RF1 SH3 domain containing ring finger 1 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr 4:169,094,259...169,270,956
Ensembl chr 4:169,094,259...169,270,956
JBrowse link
regulation of NK T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRDM1 PR/SET domain 1 involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 6:105,992,690...106,109,938
Ensembl chr 6:105,993,463...106,109,939
JBrowse link
G ZNF683 zinc finger protein 683 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr 1:26,361,634...26,374,518
Ensembl chr 1:26,361,634...26,374,522
JBrowse link
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL27 interleukin 27 involved_in IBA
IDA
(PMID:21873635)
(PMID:12734330)
GO_Central
UniProt
GO_Central
UniProt
PMID:12734330 PMID:21873635 NCBI chr16:28,499,362...28,506,834
Ensembl chr16:28,499,362...28,512,051
JBrowse link
regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in IC (PMID:29234109) ComplexPortal PMID:29234109 NCBI chr14:75,522,469...75,546,992
Ensembl chr14:75,522,455...75,546,993
JBrowse link
G CCL20 C-C motif chemokine ligand 20 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564
JBrowse link
G CCR6 C-C motif chemokine receptor 6 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chr 6:167,111,795...167,139,141
Ensembl chr 6:167,111,807...167,139,141
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit involved_in IC (PMID:29234109) ComplexPortal PMID:29234109 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
JBrowse link
G MIR301A microRNA 301a acts_upstream_of_or_within ISO (MGI:5426073|PMID:22517757) MGI PMID:22517757 MGI:5426073 NCBI chr17:59,151,136...59,151,221
Ensembl chr17:59,151,136...59,151,221
JBrowse link
regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA3 GATA binding protein 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3817343|PMID:18776904) MGI
Ensembl
PMID:18776904 GO_REF:0000107 MGI:3817343 NCBI chr10:8,045,333...8,075,198
Ensembl chr10:8,045,378...8,075,198
JBrowse link
G HLA-DRA major histocompatibility complex, class II, DR alpha involved_in IDA (PMID:15322540) UniProt
UniProt
PMID:15322540 NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 involved_in IDA (PMID:15322540) UniProt
UniProt
PMID:15322540 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,577,902...32,589,848
JBrowse link
G IRF4 interferon regulatory factor 4 involved_in NAS (PMID:12374808) UniProt
UniProt
PMID:12374808 NCBI chr 6:391,752...411,443
Ensembl chr 6:391,739...411,443
JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3817343|PMID:18776904) MGI
Ensembl
PMID:18776904 GO_REF:0000107 MGI:3817343 NCBI chr 1:155,001,750...155,018,523
Ensembl chr 1:155,002,630...155,018,523
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19751
    regulation of biological process 13156
      regulation of immune system process 1737
        regulation of leukocyte activation 772
          regulation of lymphocyte activation 657
            regulation of T cell activation 427
              regulation of alpha-beta T cell activation 134
                negative regulation of alpha-beta T cell activation + 49
                positive regulation of alpha-beta T cell activation + 84
                regulation of CD4-positive, alpha-beta T cell activation + 91
                regulation of CD8-positive, alpha-beta T cell activation + 21
                regulation of NK T cell activation + 14
                regulation of alpha-beta T cell differentiation + 83
                regulation of alpha-beta T cell proliferation + 57
Path 2
Term Annotations click to browse term
  biological_process 19751
    biological regulation 13900
      regulation of biological process 13156
        regulation of cellular process 12179
          regulation of cell activation 837
            regulation of leukocyte activation 772
              regulation of lymphocyte activation 657
                regulation of T cell activation 427
                  regulation of alpha-beta T cell activation 134
                    negative regulation of alpha-beta T cell activation + 49
                    positive regulation of alpha-beta T cell activation + 84
                    regulation of CD4-positive, alpha-beta T cell activation + 91
                    regulation of CD8-positive, alpha-beta T cell activation + 21
                    regulation of NK T cell activation + 14
                    regulation of alpha-beta T cell differentiation + 83
                    regulation of alpha-beta T cell proliferation + 57
paths to the root