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ONTOLOGY REPORT - ANNOTATIONS

Term:alpha-beta T cell differentiation
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Accession:GO:0046632 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: alpha-beta T lymphocyte differentiation
 related_synonym: alpha-beta T cell development


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alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18025176) Ensembl
MGI		 PMID:18025176 GO_REF:0000107 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307 		JBrowse link
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:18025176) MGI PMID:18025176 NCBI chr 7:20,696,659...20,735,362
Ensembl chr 7:20,700,144...20,727,410 		JBrowse link
G ADA adenosine deaminase involved_in
acts_upstream_of		 IEA
ISO		 (PMID:11067867), (PMID:12163459), (PMID:16670300)
(PMID:11067867), (PMID:16670300)		 Ensembl
MGI		 PMID:11067867 PMID:12163459 PMID:16670300 GO_REF:0000107 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160 		JBrowse link
G ANXA1 annexin A1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011 		JBrowse link
G BCL11B BCL11 transcription factor B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12717433) Ensembl
MGI		 PMID:12717433 GO_REF:0000107 NCBI chr 8:67,622,592...67,713,922
Ensembl chr 8:67,622,708...67,714,404 		JBrowse link
G BLM BLM RecQ like helicase acts_upstream_of_or_within ISO (PMID:17210642) MGI PMID:17210642 NCBI chr 3:53,408,120...53,506,728
Ensembl chr 3:53,408,217...53,473,146 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23334952) Ensembl
MGI		 PMID:23334952 GO_REF:0000107 NCBI chr16:8,222,909...8,318,179
Ensembl chr16:8,222,907...8,317,906 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15855276) Ensembl
MGI		 PMID:15855276 GO_REF:0000107 NCBI chr18:7,800,817...8,071,531
Ensembl chr18:7,801,394...8,068,132 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9462507) Ensembl
MGI		 PMID:9462507 GO_REF:0000107 NCBI chr32:28,516,002...28,633,759
Ensembl chr32:28,517,108...28,634,019 		JBrowse link
G PRR7 proline rich 7, synaptic involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:35,913,300...35,923,823
Ensembl chr 4:35,913,472...35,943,221 		JBrowse link
G RORC RAR related orphan receptor C acts_upstream_of_or_within ISO (PMID:15247480) MGI PMID:15247480 NCBI chr17:60,821,498...60,842,485
Ensembl chr17:60,821,981...60,842,453 		JBrowse link
G RPL22 ribosomal protein L22 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17555992) Ensembl
MGI		 PMID:17555992 GO_REF:0000107 NCBI chr 5:60,089,862...60,100,963
Ensembl chr 5:60,091,345...60,100,846 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of		 IEA
ISO		 (PMID:10981962) Ensembl
MGI		 PMID:10981962 GO_REF:0000107 NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903 		JBrowse link
G TCF7 transcription factor 7 acts_upstream_of_or_within ISO (PMID:9462507) MGI PMID:9462507 NCBI chr11:22,313,113...22,346,221
Ensembl chr11:22,313,105...22,344,004 		JBrowse link
G ZAP70 zeta chain of T cell receptor associated protein kinase 70 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:9208839)
(PMID:9275205)
(PMID:7630421)		 Ensembl
MGI		 PMID:7630421 PMID:9208839 PMID:9275205 GO_REF:0000107 NCBI chr10:44,887,416...44,913,845
Ensembl chr10:44,887,433...44,900,071 		JBrowse link
alpha-beta T cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RHOA ras homolog family member A involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215 		JBrowse link
beta selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RHOA ras homolog family member A involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9275205) Ensembl
MGI		 PMID:9275205 GO_REF:0000107 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583 		JBrowse link
G ZAP70 zeta chain of T cell receptor associated protein kinase 70 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9275205) Ensembl
MGI		 PMID:9275205 GO_REF:0000107 NCBI chr10:44,887,416...44,913,845
Ensembl chr10:44,887,433...44,900,071 		JBrowse link
CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARMC5 armadillo repeat containing 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28169274) Ensembl
MGI		 PMID:28169274 GO_REF:0000107 NCBI chr 6:16,782,732...16,789,490
Ensembl chr 6:16,781,860...16,788,878 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23334952) Ensembl
MGI		 PMID:23334952 GO_REF:0000107 NCBI chr16:8,222,909...8,318,179
Ensembl chr16:8,222,907...8,317,906 		JBrowse link
G CD83 CD83 molecule involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15322158) Ensembl
MGI		 PMID:15322158 GO_REF:0000107 NCBI chr35:13,489,046...13,507,897
Ensembl chr35:13,489,000...13,507,068 		JBrowse link
G FOXP3 forkhead box P3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17028180) Ensembl
MGI		 PMID:17028180 GO_REF:0000107 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758 		JBrowse link
G GIMAP1 GTPase, IMAP family member 1 acts_upstream_of_or_within ISO (PMID:20194894) MGI PMID:20194894 NCBI chr16:14,793,642...14,798,501
Ensembl chr16:14,793,464...14,795,732 		JBrowse link
G NKX2-3 NK2 homeobox 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10926756) Ensembl
MGI		 PMID:10926756 GO_REF:0000107 NCBI chr28:12,466,319...12,469,467
Ensembl chr28:12,466,368...12,469,473 		JBrowse link
G PAX1 paired box 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16093716) Ensembl
MGI		 PMID:16093716 GO_REF:0000107 NCBI chr24:1,742,570...1,752,593
Ensembl chr24:1,743,940...1,753,185 		JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:4,488,202...4,508,705
Ensembl chr17:4,487,957...4,507,181 		JBrowse link
G SASH3 SAM and SH3 domain containing 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16227612) Ensembl
MGI		 PMID:16227612 GO_REF:0000107 NCBI chr  X:100,989,605...101,003,162
Ensembl chr  X:100,989,685...101,001,885 		JBrowse link
G SATB1 SATB homeobox 1 acts_upstream_of_or_within ISO (PMID:10716941) MGI PMID:10716941 NCBI chr23:24,614,198...24,692,254
Ensembl chr23:24,593,489...24,690,977 		JBrowse link
CD4-positive, alpha-beta T cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSL3 cathepsin L family member 3 involved_in ISO (MGI:2655909|PMID:9545226) UniProt PMID:9545226 MGI:2655909 NCBI chr 1:72,215,774...72,219,093 JBrowse link
G CTSV cathepsin V involved_in ISS UniProt GO_REF:0000024 NCBI chr 1:69,937,550...69,943,316 JBrowse link
G TOX thymocyte selection associated high mobility group box involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:9,542,471...9,841,759
Ensembl chr29:9,544,561...9,842,034 		JBrowse link
CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16301745), (PMID:18573908)
(PMID:16275384)		 Ensembl
MGI		 PMID:16275384 PMID:16301745 PMID:18573908 GO_REF:0000107 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758 		JBrowse link
G FUT7 fucosyltransferase 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18573908) Ensembl
MGI		 PMID:18573908 GO_REF:0000107 NCBI chr 9:48,604,879...48,609,292
Ensembl chr 9:48,606,435...48,609,303 		JBrowse link
G IL2RG interleukin 2 receptor subunit gamma acts_upstream_of ISO (PMID:16227984) MGI PMID:16227984 NCBI chr  X:55,480,846...55,488,485
Ensembl chr  X:55,481,092...55,484,751 		JBrowse link
G NCOR1 nuclear receptor corepressor 1 acts_upstream_of_or_within ISO (PMID:11030619) MGI PMID:11030619 NCBI chr 5:39,687,530...39,837,003
Ensembl chr 5:39,687,543...39,836,464 		JBrowse link
G PLA2G2D phospholipase A2 group IID involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19564598) Ensembl
MGI		 PMID:19564598 GO_REF:0000107 NCBI chr 2:78,739,826...78,745,839
Ensembl chr 2:78,739,769...78,745,920 		JBrowse link
CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TOX thymocyte selection associated high mobility group box involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:9,542,471...9,841,759
Ensembl chr29:9,544,561...9,842,034 		JBrowse link
CD8-positive, alpha-beta intraepithelial T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPR18 G protein-coupled receptor 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25348153) Ensembl
MGI		 PMID:25348153 GO_REF:0000107 NCBI chr22:49,288,226...49,294,567
Ensembl chr22:49,288,343...49,289,338 		JBrowse link
CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GIMAP1 GTPase, IMAP family member 1 acts_upstream_of_or_within ISO (PMID:20194894) MGI PMID:20194894 NCBI chr16:14,793,642...14,798,501
Ensembl chr16:14,793,464...14,795,732 		JBrowse link
G IRF1 interferon regulatory factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11359801) Ensembl
MGI		 PMID:11359801 GO_REF:0000107 NCBI chr11:20,773,801...20,781,106
Ensembl chr11:20,760,120...20,781,608 		JBrowse link
G OTUD5 OTU deubiquitinase 5 acts_upstream_of_or_within ISO (PMID:25470037) MGI PMID:25470037 NCBI chr  X:42,079,396...42,109,129
Ensembl chr  X:42,081,561...42,108,612 		JBrowse link
G PAX1 paired box 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16093716) Ensembl
MGI		 PMID:16093716 GO_REF:0000107 NCBI chr24:1,742,570...1,752,593
Ensembl chr24:1,743,940...1,753,185 		JBrowse link
G PSMB11 proteasome subunit beta 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31915251)
(PMID:17540904)		 Ensembl
MGI		 PMID:17540904 PMID:31915251 GO_REF:0000107 NCBI chr 8:3,355,239...3,356,505 JBrowse link
G SATB1 SATB homeobox 1 acts_upstream_of_or_within ISO (PMID:10716941), (PMID:15814699) MGI PMID:10716941 PMID:15814699 NCBI chr23:24,614,198...24,692,254
Ensembl chr23:24,593,489...24,690,977 		JBrowse link
G TNFSF8 TNF superfamily member 8 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:16177108) Ensembl
MGI
TreeGrafter
GO_Central		 PMID:16177108 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr11:68,979,498...69,006,898
Ensembl chr11:68,982,360...69,007,355 		JBrowse link
CD8-positive, alpha-beta T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EOMES eomesodermin involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr23:16,476,498...16,512,406
Ensembl chr23:16,506,032...16,511,527 		JBrowse link
G IFNG interferon gamma acts_upstream_of_or_within ISO (PMID:17277142) MGI PMID:17277142 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698 		JBrowse link
CD8-positive, alpha-beta T cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8170972) Ensembl
MGI		 PMID:8170972 GO_REF:0000107 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658 		JBrowse link
G TOX thymocyte selection associated high mobility group box involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:9,542,471...9,841,759
Ensembl chr29:9,544,561...9,842,034 		JBrowse link
negative regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI3 GLI family zinc finger 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:7,800,817...8,071,531
Ensembl chr18:7,801,394...8,068,132 		JBrowse link
G IHH Indian hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:25,616,942...25,622,989 JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10981962) Ensembl
MGI		 PMID:10981962 GO_REF:0000107 NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBFB core-binding factor subunit beta involved_in ISO (MGI:3772948|PMID:18258917) UniProt PMID:18258917 MGI:3772948 NCBI chr 5:82,253,496...82,313,765
Ensembl chr 5:82,255,617...82,313,168 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:22473704) UniProt PMID:22473704 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165 		JBrowse link
G RUNX1 RUNX family transcription factor 1 involved_in ISO (MGI:3772948|PMID:18258917) UniProt PMID:18258917 MGI:3772948 NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839 		JBrowse link
G RUNX3 RUNX family transcription factor 3 involved_in ISO (MGI:3772948|PMID:18258917) UniProt PMID:18258917 MGI:3772948
negative regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC4A2 solute carrier family 4 member 2 involved_in ISO (MGI:6840447|PMID:24515893) UniProt PMID:24515893 MGI:6840447 NCBI chr16:15,111,078...15,126,618
Ensembl chr16:15,111,116...15,126,617 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 involved_in ISO (MGI:6140589|PMID:24880459) UniProt PMID:24880459 MGI:6140589 NCBI chr 6:31,511,003...31,511,995
Ensembl chr 6:31,509,268...31,511,557 		JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436 		JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL2 achaete-scute family bHLH transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:46,394,034...46,396,723
Ensembl chr18:46,395,391...46,395,975 		JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of_or_within ISO (PMID:16424184) MGI PMID:16424184 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291 		JBrowse link
G JAK3 Janus kinase 3 involved_in ISO (MGI:3719947|PMID:16020505) BHF-UCL PMID:16020505 MGI:3719947 NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:4942267|PMID:9670042) BHF-UCL PMID:9670042 MGI:4942267 NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892 		JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL2 achaete-scute family bHLH transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:46,394,034...46,396,723
Ensembl chr18:46,395,391...46,395,975 		JBrowse link
G FOXP3 forkhead box P3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758 		JBrowse link
G IL2 interleukin 2 involved_in ISO (MGI:5634593|PMID:25642768) BHF-UCL PMID:25642768 MGI:5634593 NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394 		JBrowse link
G IL4 interleukin 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18792410) TreeGrafter
MGI		 PMID:18792410 GO_REF:0000118 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534 		JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,265,836...25,312,417
Ensembl chr 7:25,233,235...25,305,174 		JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:59,881,889...59,943,271
Ensembl chr 9:59,881,966...59,929,341 		JBrowse link
G SMAD7 SMAD family member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749 		JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:24,077,752...24,086,560
Ensembl chr 9:24,077,761...24,086,261 		JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23034280) Ensembl
MGI		 PMID:23034280 GO_REF:0000107 NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:4,972,369...4,984,218
Ensembl chr15:4,972,956...4,980,371 		JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOXL3 lysyl oxidase like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:48,590,996...48,610,264
Ensembl chr17:48,591,768...48,610,392 		JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:24,077,752...24,086,560
Ensembl chr 9:24,077,761...24,086,261 		JBrowse link
G TNFSF18 TNF superfamily member 18 involved_in ISO (MGI:5551556|PMID:24107315) UniProt PMID:24107315 MGI:5551556 NCBI chr 7:25,983,064...25,994,605
Ensembl chr 7:25,963,719...25,992,801 		JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011 		JBrowse link
G ASCL2 achaete-scute family bHLH transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:46,394,034...46,396,723
Ensembl chr18:46,395,391...46,395,975 		JBrowse link
G BCL6 BCL6 transcription repressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12594267) Ensembl
MGI		 PMID:12594267 GO_REF:0000107 NCBI chr34:20,112,302...20,135,705
Ensembl chr34:20,113,322...20,124,704 		JBrowse link
G HLX H2.0 like homeobox involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16424184) Ensembl
MGI		 PMID:16424184 GO_REF:0000107 NCBI chr38:15,538,744...15,543,686
Ensembl chr38:15,539,029...15,542,152 		JBrowse link
G LOC111089966 zinc finger protein 271 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:54,714,912...54,727,638 JBrowse link
G RTP2 receptor transporter protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:20,087,395...20,091,248
Ensembl chr34:20,087,226...20,115,428 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:48,916,446...48,977,183
Ensembl chr10:48,972,842...48,974,452 		JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RC3H1 ring finger and CCCH-type domains 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15917799) Ensembl
MGI		 PMID:15917799 GO_REF:0000107 NCBI chr 7:25,265,836...25,312,417
Ensembl chr 7:25,233,235...25,305,174 		JBrowse link
NK T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF2 activating transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:19,032,376...19,103,382
Ensembl chr36:19,010,717...19,103,292 		JBrowse link
G CD1D CD1d molecule involved_in ISO (MGI:87097|PMID:9133426) CACAO PMID:9133426 MGI:87097 NCBI chr38:23,489,169...23,491,712 JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19620306) Ensembl
MGI		 PMID:19620306 GO_REF:0000107 NCBI chr17:22,340,469...22,364,994
Ensembl chr17:22,341,322...22,361,772 		JBrowse link
G ITK IL2 inducible T cell kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18292523) Ensembl
MGI
TreeGrafter		 PMID:18292523 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:52,902,886...52,966,465
Ensembl chr 4:52,902,871...52,966,542 		JBrowse link
G PSAP prosaposin acts_upstream_of_or_within ISO (PMID:14684827) MGI PMID:14684827 NCBI chr 4:22,571,095...22,603,880
Ensembl chr 4:22,572,153...22,603,848 		JBrowse link
G STK17A serine/threonine kinase 17a involved_in ISO (PMID:26423156) MGI PMID:26423156 NCBI chr18:6,588,821...6,626,236
Ensembl chr18:6,590,105...6,626,245 		JBrowse link
G TXK TXK tyrosine kinase acts_upstream_of_or_within ISO (PMID:18292523) MGI PMID:18292523 NCBI chr13:43,911,881...43,977,499
Ensembl chr13:43,914,534...43,976,655 		JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436 		JBrowse link
G ZNF683 zinc finger protein 683 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22885984) Ensembl
MGI		 PMID:22885984 GO_REF:0000107 NCBI chr 2:73,656,842...73,667,621
Ensembl chr 2:73,658,525...73,667,605 		JBrowse link
NK T cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TOX thymocyte selection associated high mobility group box involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:9,542,471...9,841,759
Ensembl chr29:9,544,561...9,842,034 		JBrowse link
positive regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11067867), (PMID:16670300)
(PMID:11067867), (PMID:12163459), (PMID:16670300)		 Ensembl
MGI		 PMID:11067867 PMID:12163459 PMID:16670300 GO_REF:0000107 NCBI chr24:32,083,786...32,119,810
Ensembl chr24:32,083,931...32,111,160 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:7,800,817...8,071,531
Ensembl chr18:7,801,394...8,068,132 		JBrowse link
G IHH Indian hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:25,616,942...25,622,989 JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15064401) Ensembl
MGI		 PMID:15064401 GO_REF:0000107 NCBI chr 7:38,253,257...38,346,400
Ensembl chr 7:38,253,407...38,343,345 		JBrowse link
G NKAP NFKB activating protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:91,922,326...91,956,566
Ensembl chr  X:91,923,550...91,956,414 		JBrowse link
G PNP purine nucleoside phosphorylase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16964310) MGI
Ensembl		 PMID:16964310 GO_REF:0000107 NCBI chr15:17,808,454...17,815,987
Ensembl chr15:17,808,461...17,815,676 		JBrowse link
G RHOA ras homolog family member A involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9275205) Ensembl
MGI		 PMID:9275205 GO_REF:0000107 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583 		JBrowse link
G ZAP70 zeta chain of T cell receptor associated protein kinase 70 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7630421)
(PMID:9208839)
(PMID:9275205)		 Ensembl
MGI		 PMID:7630421 PMID:9208839 PMID:9275205 GO_REF:0000107 NCBI chr10:44,887,416...44,913,845
Ensembl chr10:44,887,433...44,900,071 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD83 CD83 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15322158) Ensembl
MGI		 PMID:15322158 GO_REF:0000107 NCBI chr35:13,489,046...13,507,897
Ensembl chr35:13,489,000...13,507,068 		JBrowse link
G FOXP3 forkhead box P3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17028180) Ensembl
MGI		 PMID:17028180 GO_REF:0000107 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439 		JBrowse link
G SASH3 SAM and SH3 domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16227612) Ensembl
MGI		 PMID:16227612 GO_REF:0000107 NCBI chr  X:100,989,605...101,003,162
Ensembl chr  X:100,989,685...101,001,885 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 involved_in ISO (MGI:6140589|PMID:24880459) UniProt PMID:24880459 MGI:6140589 NCBI chr 6:31,511,003...31,511,995
Ensembl chr 6:31,509,268...31,511,557 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:4819294|PMID:20639485) BHF-UCL PMID:20639485 MGI:4819294 NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892 		JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLA-DRA MHC class II DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:2,133,026...2,137,825
Ensembl chr12:2,132,499...2,168,975 		JBrowse link
G FOXP3 forkhead box P3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12612578)
(PMID:16275384)
(PMID:16301745), (PMID:18573908)		 Ensembl
MGI		 PMID:12612578 PMID:16275384 PMID:16301745 PMID:18573908 GO_REF:0000107 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758 		JBrowse link
G HLA-DRB1 MHC class II DLA DRB1 beta chain involved_in ISO (PMID:28467828) UniProt PMID:28467828 NCBI chr12:2,151,409...2,164,564 JBrowse link
G IL2RG interleukin 2 receptor subunit gamma acts_upstream_of_or_within ISO (PMID:16227984) MGI PMID:16227984 NCBI chr  X:55,480,846...55,488,485
Ensembl chr  X:55,481,092...55,484,751 		JBrowse link
G KLHL25 kelch like family member 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:49,339,576...49,375,473
Ensembl chr 3:49,348,982...49,351,663 		JBrowse link
G LOC100687459 GTPase IMAP family member 5 ISO RGD PMID:15778366 RGD:2303772 NCBI chr16:14,887,308...14,895,522 JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698 		JBrowse link
G LGALS9 galectin 9 involved_in ISO (PMID:20209097) UniProt PMID:20209097 NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391 		JBrowse link
positive regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBFB core-binding factor subunit beta involved_in ISO (MGI:3772948|PMID:18258917) UniProt PMID:18258917 MGI:3772948 NCBI chr 5:82,253,496...82,313,765
Ensembl chr 5:82,255,617...82,313,168 		JBrowse link
G LOC484306 leukocyte immunoglobulin-like receptor subfamily B member 3 involved_in ISO (PMID:18420485) ARUK-UCL PMID:18420485 NCBI chr 1:102,779,562...102,786,924 JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439 		JBrowse link
G RUNX1 RUNX family transcription factor 1 involved_in ISO (MGI:3772948|PMID:18258917) UniProt PMID:18258917 MGI:3772948 NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839 		JBrowse link
G RUNX3 RUNX family transcription factor 3 involved_in ISO (MGI:3772948|PMID:18258917) UniProt PMID:18258917 MGI:3772948
positive regulation of NK T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP3B1 adaptor related protein complex 3 subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14557411) Ensembl
MGI		 PMID:14557411 GO_REF:0000107 NCBI chr 3:28,481,974...28,748,095
Ensembl chr 3:28,481,038...28,751,258 		JBrowse link
G AP3D1 adaptor related protein complex 3 subunit delta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14557411) Ensembl
MGI		 PMID:14557411 GO_REF:0000107 NCBI chr20:56,893,479...56,932,460
Ensembl chr20:56,893,535...56,931,830 		JBrowse link
G CD1D CD1d molecule acts_upstream_of_or_within ISO (PMID:9133426)
(PMID:10201995)		 MGI PMID:9133426 PMID:10201995 NCBI chr38:23,489,169...23,491,712 JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16973387) Ensembl
MGI		 PMID:16973387 GO_REF:0000107 NCBI chr23:13,886,869...13,946,480
Ensembl chr23:13,889,000...13,977,636 		JBrowse link
G ZBTB16 zinc finger and BTB domain containing 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:19,082,594...19,284,360
Ensembl chr 5:19,087,154...19,267,628 		JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 involved_in ISO (MGI:3576832|PMID:15845453) BHF-UCL PMID:15845453 MGI:3576832 NCBI chr11:51,357,706...51,359,207
Ensembl chr11:51,340,530...51,359,365 		JBrowse link
G HLX H2.0 like homeobox involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16424184) Ensembl
MGI		 PMID:16424184 GO_REF:0000107 NCBI chr38:15,538,744...15,543,686
Ensembl chr38:15,539,029...15,542,152 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894097) Ensembl
MGI		 PMID:11894097 GO_REF:0000107 NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:48,916,446...48,977,183
Ensembl chr10:48,972,842...48,974,452 		JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MALT1 MALT1 paracaspase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:17,351,458...17,412,591
Ensembl chr 1:17,354,926...17,403,927 		JBrowse link
G MIR326 microRNA mir-326 acts_upstream_of_or_within ISO (PMID:19838199) MGI PMID:19838199 NCBI chr21:23,240,463...23,240,553
Ensembl chr21:23,240,463...23,240,553 		JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chr 1:116,763,371...116,770,683
Ensembl chr 1:116,757,289...116,772,325 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:8,147,160...8,154,401
Ensembl chr33:8,073,840...8,154,561 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) UniProt PMID:26098997 MGI:5689221 NCBI chr 8:251,776...313,290
Ensembl chr 8:253,407...313,059 		JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRD2 bromodomain containing 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr12:2,534,034...2,546,029
Ensembl chr12:2,534,034...2,546,029 		JBrowse link
G BRD4 bromodomain containing 4 involved_in ISO (MGI:6106706|PMID:28262505) UniProt PMID:28262505 MGI:6106706 NCBI chr20:46,844,795...46,927,620
Ensembl chr20:46,891,514...46,927,608 		JBrowse link
G EP300 E1A binding protein p300 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:24,076,538...24,156,708
Ensembl chr10:24,077,971...24,156,396 		JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:635,384...640,715
Ensembl chr10:638,719...640,359 		JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL18 interleukin 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348 		JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of_or_within ISO (PMID:16424184) MGI PMID:16424184 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291 		JBrowse link
G IL6 interleukin 6 acts_upstream_of_or_within ISO (PMID:12594267) MGI PMID:12594267 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (MGI:5689221|PMID:26098997) UniProt PMID:26098997 MGI:5689221 NCBI chr 8:251,776...313,290
Ensembl chr 8:253,407...313,059 		JBrowse link
G PRKCZ protein kinase C zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:57,012,020...57,113,346
Ensembl chr 5:57,012,070...57,112,664 		JBrowse link
G RARA retinoic acid receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:22,254,803...22,298,614
Ensembl chr 9:22,254,806...22,289,459 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (MGI:4943387|PMID:18354165) BHF-UCL PMID:18354165 MGI:4943387 NCBI chr 7:25,883,297...25,909,608
Ensembl chr 7:25,883,251...25,906,892 		JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SHB SH2 domain containing adaptor protein B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24645804) Ensembl
MGI		 PMID:24645804 GO_REF:0000107 NCBI chr11:54,189,580...54,329,004
Ensembl chr11:54,189,843...54,329,325 		JBrowse link
regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKLE1 ankyrin repeat and LEM domain containing 1 NOT|involved_in ISO (MGI:5800654|PMID:27010503) UniProt PMID:27010503 MGI:5800654 NCBI chr20:45,461,135...45,465,922
Ensembl chr20:45,461,676...45,465,417 		JBrowse link
regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SH3RF1 SH3 domain containing ring finger 1 involved_in ISO (MGI:6158776|PMID:27084103) UniProt PMID:27084103 MGI:6158776 NCBI chr25:20,025,920...20,208,470
Ensembl chr25:20,015,915...20,205,946 		JBrowse link
regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZBTB7B zinc finger and BTB domain containing 7B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18776904) Ensembl
MGI		 PMID:18776904 GO_REF:0000107 NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436 		JBrowse link
regulation of NK T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRDM1 PR/SET domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:63,454,242...63,495,278
Ensembl chr12:63,470,974...63,495,579 		JBrowse link
G ZNF683 zinc finger protein 683 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:73,656,842...73,667,621
Ensembl chr 2:73,658,525...73,667,605 		JBrowse link
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL27 interleukin 27 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:18,243,988...18,248,369
Ensembl chr 6:18,244,040...18,247,635 		JBrowse link
regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL20 C-C motif chemokine ligand 20 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chr25:40,506,385...40,509,903
Ensembl chr25:40,506,753...40,509,709 		JBrowse link
G CCR6 C-C motif chemokine receptor 6 NOT|involved_in ISO (MGI:3820359|PMID:19050256) UniProt PMID:19050256 MGI:3820359 NCBI chr 1:54,932,798...54,960,646
Ensembl chr 1:54,932,690...54,959,740 		JBrowse link
G MIR301A microRNA mir-301a acts_upstream_of_or_within ISO (PMID:22517757) MGI PMID:22517757 NCBI chr 9:33,724,572...33,724,655
Ensembl chr 9:33,724,571...33,724,655 		JBrowse link
regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLA-DRA MHC class II DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:2,133,026...2,137,825
Ensembl chr12:2,132,499...2,168,975 		JBrowse link
G GATA3 GATA binding protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18776904) Ensembl
MGI		 PMID:18776904 GO_REF:0000107 NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760 		JBrowse link
G HLA-DRB1 MHC class II DLA DRB1 beta chain involved_in ISO (PMID:15322540) UniProt PMID:15322540 NCBI chr12:2,151,409...2,164,564 JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18776904) Ensembl
MGI		 PMID:18776904 GO_REF:0000107 NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436 		JBrowse link
T follicular helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL2 achaete-scute family bHLH transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:46,394,034...46,396,723
Ensembl chr18:46,395,391...46,395,975 		JBrowse link
G FOXP1 forkhead box P1 involved_in ISO (MGI:5607369|PMID:24859450) UniProt PMID:24859450 MGI:5607369 NCBI chr20:20,438,631...21,020,516
Ensembl chr20:20,788,433...21,016,397 		JBrowse link
G GPR183 G protein-coupled receptor 183 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:49,332,665...49,347,721
Ensembl chr22:49,333,188...49,347,593 		JBrowse link
G IL21 interleukin 21 involved_in ISS UniProt GO_REF:0000024 NCBI chr19:17,641,833...17,651,275
Ensembl chr19:17,641,833...17,651,266 		JBrowse link
G IL6 interleukin 6 involved_in ISO (MGI:5450752|PMID:23045607) UniProt PMID:23045607 MGI:5450752 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23583643) Ensembl
MGI		 PMID:23583643 GO_REF:0000107 NCBI chr 7:25,265,836...25,312,417
Ensembl chr 7:25,233,235...25,305,174 		JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23583643) Ensembl
MGI		 PMID:23583643 GO_REF:0000107 NCBI chr 9:59,881,889...59,943,271
Ensembl chr 9:59,881,966...59,929,341 		JBrowse link
T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRACR2A calcium release activated channel regulator 2A involved_in ISO (MGI:6195365|PMID:29987160)
(PMID:29987160)		 UniProt PMID:29987160 MGI:6195365 NCBI chr27:41,090,906...41,228,677
Ensembl chr27:41,094,009...41,217,919 		JBrowse link
G HLX H2.0 like homeobox involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16424184) Ensembl
MGI		 PMID:16424184 GO_REF:0000107 NCBI chr38:15,538,744...15,543,686
Ensembl chr38:15,539,029...15,542,152 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:15944249) UniProt PMID:15944249 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165 		JBrowse link
G IL18R1 interleukin 18 receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10227969) Ensembl
MGI		 PMID:10227969 GO_REF:0000107 NCBI chr10:40,614,336...40,653,300
Ensembl chr10:40,615,312...40,653,454 		JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of ISO (PMID:16424184) MGI PMID:16424184 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:28,516,002...28,633,759
Ensembl chr32:28,517,108...28,634,019 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:8,147,160...8,154,401
Ensembl chr33:8,073,840...8,154,561 		JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16081776) Ensembl
MGI		 PMID:16081776 GO_REF:0000107 NCBI chr 1:110,436,677...110,466,709
Ensembl chr 1:110,436,662...110,466,809 		JBrowse link
G SEMA4A semaphorin 4A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:41,670,814...41,695,349
Ensembl chr 7:41,672,120...41,692,460 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:1,566,563...1,685,378
Ensembl chr37:1,566,585...1,829,894 		JBrowse link
G TMEM98 transmembrane protein 98 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:40,130,421...40,144,120
Ensembl chr 9:40,128,885...40,144,181 		JBrowse link
T-helper 1 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL4 interleukin 4 acts_upstream_of_or_within ISO (PMID:20706986) MGI PMID:20706986 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:84,818,893...84,939,283
Ensembl chr 2:84,787,708...84,939,114 		JBrowse link
G SPN sialophorin involved_in ISO (PMID:18036228) UniProt PMID:18036228 NCBI chr 6:17,770,303...17,774,946 JBrowse link
G STAT6 signal transducer and activator of transcription 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20706986) Ensembl
MGI		 PMID:20706986 GO_REF:0000107 NCBI chr10:1,232,515...1,247,011
Ensembl chr10:1,233,691...1,247,075 		JBrowse link
G TBX21 T-box transcription factor 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:24,077,752...24,086,560
Ensembl chr 9:24,077,761...24,086,261 		JBrowse link
T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:48,537,036...48,561,154 JBrowse link
G ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:12,565,173...12,601,152
Ensembl chr28:12,564,727...12,600,240 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:8,147,160...8,154,401
Ensembl chr33:8,073,840...8,154,561 		JBrowse link
G RORA RAR related orphan receptor A involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:25,315,974...26,026,708
Ensembl chr30:25,325,275...26,026,623 		JBrowse link
G RORC RAR related orphan receptor C involved_in
acts_upstream_of_or_within		 ISO (MGI:3692468|PMID:16990136), (MGI:3772713|PMID:18164222)
(PMID:18792410)
(PMID:20383124)		 GO_Central
MGI		 PMID:16990136 PMID:18164222 PMID:18792410 PMID:20383124 MGI:3692468 MGI:3772713 NCBI chr17:60,821,498...60,842,485
Ensembl chr17:60,821,981...60,842,453 		JBrowse link
T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:48,537,036...48,561,154 JBrowse link
G IL6 interleukin 6 involved_in ISS
IEA		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000024 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G IL6R interleukin 6 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,877,731...42,920,149
Ensembl chr 7:42,880,885...42,920,090 		JBrowse link
G IRF4 interferon regulatory factor 4 involved_in ISO (MGI:5448096|PMID:22983707) UniProt PMID:22983707 MGI:5448096 NCBI chr35:760,367...782,314
Ensembl chr35:767,011...781,339 		JBrowse link
G LY9 lymphocyte antigen 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:21,522,898...21,554,652
Ensembl chr38:21,523,637...21,554,579 		JBrowse link
G OTUD5 OTU deubiquitinase 5 acts_upstream_of_or_within ISO (PMID:25470037) MGI PMID:25470037 NCBI chr  X:42,079,396...42,109,129
Ensembl chr  X:42,081,561...42,108,612 		JBrowse link
G SLAMF6 SLAM family member 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr38:21,742,228...21,769,521
Ensembl chr38:21,742,301...21,764,494 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BATF basic leucine zipper ATF-like transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:48,537,036...48,561,154 JBrowse link
G BCL3 BCL3 transcription coactivator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16081776) Ensembl
MGI		 PMID:16081776 GO_REF:0000107 NCBI chr 1:110,620,850...110,628,830
Ensembl chr 1:110,620,827...110,654,771 		JBrowse link
G BCL6 BCL6 transcription repressor involved_in
acts_upstream_of		 IEA
ISO		 (PMID:12594267) Ensembl
MGI		 PMID:12594267 GO_REF:0000107 NCBI chr34:20,112,302...20,135,705
Ensembl chr34:20,113,322...20,124,704 		JBrowse link
G GATA3 GATA binding protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20706986) Ensembl
MGI		 PMID:20706986 GO_REF:0000107 NCBI chr 2:28,068,143...28,098,445
Ensembl chr 2:28,069,051...28,087,760 		JBrowse link
G HLX H2.0 like homeobox involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16424184) Ensembl
MGI		 PMID:16424184 GO_REF:0000107 NCBI chr38:15,538,744...15,543,686
Ensembl chr38:15,539,029...15,542,152 		JBrowse link
G IL4 interleukin 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20706986) TreeGrafter
MGI		 PMID:20706986 GO_REF:0000118 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534 		JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of ISO (PMID:16424184) MGI PMID:16424184 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291 		JBrowse link
G IL6 interleukin 6 acts_upstream_of ISO (PMID:12594267) MGI PMID:12594267 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G KMT2A lysine methyltransferase 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:15,212,559...15,302,825
Ensembl chr 5:15,217,348...15,270,971 		JBrowse link
G MEN1 menin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:52,346,747...52,352,884
Ensembl chr18:52,346,933...52,353,340 		JBrowse link
G MYB MYB proto-oncogene, transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:27,908,309...27,991,984
Ensembl chr 1:27,908,364...27,991,969 		JBrowse link
G RTP2 receptor transporter protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:20,087,395...20,091,248
Ensembl chr34:20,087,226...20,115,428 		JBrowse link
T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha acts_upstream_of_or_within ISO (PMID:8434133) MGI PMID:8434133 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869 		JBrowse link
G IL12B interleukin 12B involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:51,178,637...51,194,606
Ensembl chr 4:51,183,568...51,193,228 		JBrowse link
G PDP2 pyruvate dehydrogenase phosphatase catalytic subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:82,421,531...82,428,600
Ensembl chr 5:82,424,978...82,426,573 		JBrowse link
G PTGER4 prostaglandin E receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:68,663,362...68,676,241
Ensembl chr 4:68,663,364...68,676,358 		JBrowse link
G RORC RAR related orphan receptor C involved_in ISO (MGI:2686818|PMID:14691482) UniProt PMID:14691482 MGI:2686818 NCBI chr17:60,821,498...60,842,485
Ensembl chr17:60,821,981...60,842,453 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17878
    immune system process 2491
      leukocyte activation 1022
        lymphocyte activation 829
          T cell activation 582
            T cell differentiation 324
              alpha-beta T cell differentiation 141
                CD4-positive, alpha-beta T cell differentiation + 102
                CD8-positive, alpha-beta T cell differentiation + 20
                NK T cell differentiation + 15
                alpha-beta T cell differentiation involved in immune response + 79
                alpha-beta T cell lineage commitment + 24
                alpha-beta intraepithelial T cell differentiation + 1
                beta selection 3
                negative regulation of alpha-beta T cell differentiation + 30
                positive regulation of alpha-beta T cell differentiation + 53
                regulation of alpha-beta T cell differentiation + 78
Path 2
Term Annotations click to browse term
  biological_process 17878
    cellular process 16920
      cellular developmental process 4609
        cell differentiation 4608
          cell development 3263
            hemopoiesis 1054
              leukocyte differentiation 674
                mononuclear cell differentiation 552
                  lymphocyte differentiation 454
                    T cell differentiation 324
                      alpha-beta T cell differentiation 141
                        CD4-positive, alpha-beta T cell differentiation + 102
                        CD8-positive, alpha-beta T cell differentiation + 20
                        NK T cell differentiation + 15
                        alpha-beta T cell differentiation involved in immune response + 79
                        alpha-beta T cell lineage commitment + 24
                        alpha-beta intraepithelial T cell differentiation + 1
                        beta selection 3
                        negative regulation of alpha-beta T cell differentiation + 30
                        positive regulation of alpha-beta T cell differentiation + 53
                        regulation of alpha-beta T cell differentiation + 78
paths to the root