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ONTOLOGY REPORT - ANNOTATIONS

Term:gamma-delta T cell activation
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Accession:GO:0046629 term browser browse the term
Definition:The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
Synonyms:exact_synonym: gamma-delta T lymphocyte activation


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gamma-delta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXADR CXADR Ig-like cell adhesion molecule involved_in ISO (MGI:4822257|PMID:20813954) UniProt PMID:20813954 MGI:4822257 NCBI chr13:182,134,416...182,185,977
Ensembl chr13:182,134,566...182,185,950 		JBrowse link
G ITK IL2 inducible T cell kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:66,010,766...66,082,263
Ensembl chr16:66,010,772...66,082,185 		JBrowse link
G JAML junction adhesion molecule like involved_in ISO (MGI:4822257|PMID:20813954) UniProt PMID:20813954 MGI:4822257 NCBI chr 9:45,506,496...45,537,304
Ensembl chr 9:45,505,907...45,534,863 		JBrowse link
G LOC100153163 MHC class I polypeptide-related sequence B involved_in ISO (PMID:9497295) UniProt PMID:9497295 NCBI chr 7:23,596,900...23,610,431 JBrowse link
CD8-positive, gamma-delta intraepithelial T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR9 C-C motif chemokine receptor 9 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5629467|PMID:25348153) MGI
Ensembl		 PMID:25348153 GO_REF:0000107 MGI:5629467 NCBI chr13:29,033,609...29,051,227
Ensembl chr13:29,033,570...29,054,598 		JBrowse link
G GPR18 G protein-coupled receptor 18 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5629467|PMID:25348153) MGI
Ensembl		 PMID:25348153 GO_REF:0000107 MGI:5629467 NCBI chr11:68,187,402...68,191,622
Ensembl chr11:68,187,327...68,191,269 		JBrowse link
G LOC100523789 NKG2-A/NKG2-B type II integral membrane protein involved_in ISO (PMID:18064301) UniProt PMID:18064301 NCBI chr 5:61,621,869...61,633,693 JBrowse link
gamma-delta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G JAG2 jagged canonical Notch ligand 2 involved_in IEA Ensembl GO_REF:0000107
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of ISO (MGI:70338|PMID:7807014) MGI PMID:7807014 MGI:70338 NCBI chr 6:88,719,886...88,745,922
Ensembl chr 6:88,720,176...88,745,914 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of		 IEA
ISO		 (MGI:70338|PMID:7807014) Ensembl
MGI		 PMID:7807014 GO_REF:0000107 MGI:70338 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,560,073...21,601,308 		JBrowse link
G SOX13 SRY-box transcription factor 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:64,745,762...64,780,942
Ensembl chr 9:64,731,969...64,780,942 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A acts_upstream_of ISO (MGI:3054293|PMID:15294943) MGI PMID:15294943 MGI:3054293 NCBI chr12:20,474,221...20,498,785
Ensembl chr12:20,474,227...20,499,138 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B involved_in
acts_upstream_of		 IEA
ISO		 (MGI:3054293|PMID:15294943) Ensembl
MGI		 PMID:15294943 GO_REF:0000107 MGI:3054293 NCBI chr12:20,498,103...20,574,365
Ensembl chr12:20,508,404...20,574,266 		JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of
involved_in		 ISO
IEA		 (MGI:77314|PMID:7477352)
(MGI:83585|PMID:8790395)		 MGI
Ensembl		 PMID:7477352 PMID:8790395 GO_REF:0000107 MGI:77314 MGI:83585 NCBI chr14:2,103,706...2,160,886
Ensembl chr14:2,056,670...2,161,171 		JBrowse link
G TCF7 transcription factor 7 involved_in ISO (MGI:6276541|PMID:30413363) UniProt PMID:30413363 MGI:6276541 NCBI chr 2:136,422,740...136,456,323
Ensembl chr 2:136,422,940...136,457,910 		JBrowse link
gamma-delta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH5 alkB homolog 5, RNA demethylase involved_in
acts_upstream_of		 IEA
ISO		 (MGI:7437433|PMID:35939687) Ensembl
UniProt		 PMID:35939687 GO_REF:0000107 MGI:7437433 NCBI chr12:60,507,662...60,530,239
Ensembl chr12:60,507,667...60,529,733 		JBrowse link
positive regulation of gamma-delta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GIMAP5 GTPase, IMAP family member 5 ISO RGD PMID:11859104 RGD:625608 NCBI chr18:6,363,443...6,371,725 JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (MGI:70338|PMID:7807014) MGI PMID:7807014 MGI:70338 NCBI chr 6:88,719,886...88,745,922
Ensembl chr 6:88,720,176...88,745,914 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:113,824,511...113,944,078
Ensembl chr 8:113,825,161...113,944,070 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:19,677,613...19,720,550
Ensembl chr 5:19,677,875...19,723,132 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:70338|PMID:7807014) MGI
Ensembl		 PMID:7807014 GO_REF:0000107 MGI:70338 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,560,073...21,601,308 		JBrowse link
G SOX13 SRY-box transcription factor 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:64,745,762...64,780,942
Ensembl chr 9:64,731,969...64,780,942 		JBrowse link
G SOX4 SRY-box transcription factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:16,886,834...16,895,488
Ensembl chr 7:16,891,319...16,892,752 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO (MGI:3054293|PMID:15294943) MGI PMID:15294943 MGI:3054293 NCBI chr12:20,474,221...20,498,785
Ensembl chr12:20,474,227...20,499,138 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3054293|PMID:15294943) Ensembl
MGI		 PMID:15294943 GO_REF:0000107 MGI:3054293 NCBI chr12:20,498,103...20,574,365
Ensembl chr12:20,508,404...20,574,266 		JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:83585|PMID:8790395)
(MGI:77314|PMID:7477352)		 MGI
Ensembl		 PMID:7477352 PMID:8790395 GO_REF:0000107 MGI:77314 MGI:83585 NCBI chr14:2,103,706...2,160,886
Ensembl chr14:2,056,670...2,161,171 		JBrowse link
regulation of gamma-delta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EGR3 early growth response 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5139961|PMID:21737317) MGI
Ensembl		 PMID:21737317 GO_REF:0000107 MGI:5139961 NCBI chr14:6,943,184...6,948,507
Ensembl chr14:6,944,935...6,948,580 		JBrowse link
G RORC RAR related orphan receptor C acts_upstream_of_or_within ISO (MGI:5139961|PMID:21737317) MGI PMID:21737317 MGI:5139961 NCBI chr 4:97,374,672...97,399,017
Ensembl chr 4:97,375,136...97,400,209 		JBrowse link
G SOX13 SRY-box transcription factor 13 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5139961|PMID:21737317) Ensembl
MGI		 PMID:21737317 GO_REF:0000107 MGI:5139961 NCBI chr 9:64,745,762...64,780,942
Ensembl chr 9:64,731,969...64,780,942 		JBrowse link
G TCF7 transcription factor 7 involved_in ISO (MGI:5486619|PMID:23562159) UniProt PMID:23562159 MGI:5486619 NCBI chr 2:136,422,740...136,456,323
Ensembl chr 2:136,422,940...136,457,910 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17410
    immune system process 2424
      leukocyte activation 1005
        lymphocyte activation 819
          T cell activation 579
            gamma-delta T cell activation 22
              gamma-delta T cell activation involved in immune response + 0
              gamma-delta T cell differentiation + 17
              gamma-delta T cell proliferation + 1
              negative regulation of gamma-delta T cell activation + 0
              positive regulation of gamma-delta T cell activation + 10
              regulation of gamma-delta T cell activation + 13
Path 2
Term Annotations click to browse term
  biological_process 17410
    cellular process 16454
      cell activation 1147
        leukocyte activation 1005
          lymphocyte activation 819
            T cell activation 579
              gamma-delta T cell activation 22
                gamma-delta T cell activation involved in immune response + 0
                gamma-delta T cell differentiation + 17
                gamma-delta T cell proliferation + 1
                negative regulation of gamma-delta T cell activation + 0
                positive regulation of gamma-delta T cell activation + 10
                regulation of gamma-delta T cell activation + 13
paths to the root