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ONTOLOGY REPORT - ANNOTATIONS

Term:gamma-delta T cell activation
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Accession:GO:0046629 term browser browse the term
Definition:The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
Synonyms:exact_synonym: gamma-delta T lymphocyte activation


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gamma-delta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXADR CXADR Ig-like cell adhesion molecule involved_in ISO (MGI:4822257|PMID:20813954) UniProt PMID:20813954 MGI:4822257 NCBI chr21:4,246,779...4,367,369
Ensembl chr21:17,636,952...17,693,324 		JBrowse link
G ITK IL2 inducible T cell kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:152,582,125...152,656,211
Ensembl chr 5:159,204,016...159,277,689 		JBrowse link
G JAML junction adhesion molecule like involved_in ISO (MGI:4822257|PMID:20813954) UniProt PMID:20813954 MGI:4822257 NCBI chr11:113,027,829...113,062,344
Ensembl chr11:116,960,436...116,994,373 		JBrowse link
G MICB MHC class I polypeptide-related sequence B involved_in ISO (PMID:9497295) UniProt PMID:9497295 NCBI chr 6:31,151,935...31,167,567 JBrowse link
CD8-positive, gamma-delta intraepithelial T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR9 C-C motif chemokine receptor 9 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5629467|PMID:25348153) MGI
Ensembl		 PMID:25348153 GO_REF:0000107 MGI:5629467 NCBI chr 3:45,719,655...45,810,964
Ensembl chr 3:46,900,845...46,917,443 		JBrowse link
G GPR18 G protein-coupled receptor 18 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5629467|PMID:25348153) MGI
Ensembl		 PMID:25348153 GO_REF:0000107 MGI:5629467 NCBI chr13:80,423,534...80,427,604
Ensembl chr13:99,562,589...99,563,584 		JBrowse link
G LOC100990924 NKG2-A/NKG2-B type II integral membrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:10,469,351...10,576,060
Ensembl chr12:10,720,723...10,744,046 		JBrowse link
gamma-delta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G JAG2 jagged canonical Notch ligand 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:85,785,586...85,812,056
Ensembl chr14:105,569,837...105,585,878 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of ISO (MGI:70338|PMID:7807014) MGI PMID:7807014 MGI:70338 NCBI chr 1:31,560,229...31,572,391
Ensembl chr 1:32,565,739...32,579,923 		JBrowse link
G LOC100988550 signal transducer and activator of transcription 5A acts_upstream_of ISO (MGI:3054293|PMID:15294943) MGI PMID:15294943 MGI:3054293 NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783 		JBrowse link
G LOC100989105 signal transducer and activator of transcription 5B acts_upstream_of
involved_in		 ISO
IEA		 (MGI:3054293|PMID:15294943) MGI
Ensembl		 PMID:15294943 GO_REF:0000107 MGI:3054293 NCBI chr17:15,040,303...15,116,682
Ensembl chr17:15,306,418...15,336,463 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of
involved_in		 ISO
IEA		 (MGI:70338|PMID:7807014) MGI
Ensembl		 PMID:7807014 GO_REF:0000107 MGI:70338 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994 		JBrowse link
G SOX13 SRY-box transcription factor 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:179,675,017...179,730,628
Ensembl chr 1:184,003,907...184,016,504 		JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of
involved_in		 ISO
IEA		 (MGI:77314|PMID:7477352)
(MGI:83585|PMID:8790395)		 MGI
Ensembl		 PMID:7477352 PMID:8790395 GO_REF:0000107 MGI:77314 MGI:83585 NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101 		JBrowse link
G TCF7 transcription factor 7 involved_in ISO (MGI:6276541|PMID:30413363) UniProt PMID:30413363 MGI:6276541 NCBI chr 5:129,518,134...129,549,972
Ensembl chr 5:135,671,095...135,702,734 		JBrowse link
gamma-delta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALKBH5 alkB homolog 5, RNA demethylase involved_in
acts_upstream_of		 IEA
ISO		 (MGI:7437433|PMID:35939687) Ensembl
UniProt		 PMID:35939687 GO_REF:0000107 MGI:7437433 NCBI chr17:32,725,632...32,753,021
Ensembl chr17:38,003,362...38,030,715 		JBrowse link
positive regulation of gamma-delta T cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LILRB1 leukocyte immunoglobulin like receptor B1 involved_in ISO (PMID:21233315) UniProt PMID:21233315 NCBI chr19:51,561,376...51,578,564 JBrowse link
positive regulation of gamma-delta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GIMAP5 GTPase, IMAP family member 5 ISO RGD PMID:11859104 RGD:625608 NCBI chr 7:142,319,479...142,326,035 JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (MGI:70338|PMID:7807014) MGI PMID:7807014 MGI:70338 NCBI chr 1:31,560,229...31,572,391
Ensembl chr 1:32,565,739...32,579,923 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:100,552,959...100,674,156
Ensembl chr 4:111,125,312...111,245,980 		JBrowse link
G LOC100988550 signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO (MGI:3054293|PMID:15294943) MGI PMID:15294943 MGI:3054293 NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783 		JBrowse link
G LOC100989105 signal transducer and activator of transcription 5B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3054293|PMID:15294943) MGI
Ensembl		 PMID:15294943 GO_REF:0000107 MGI:3054293 NCBI chr17:15,040,303...15,116,682
Ensembl chr17:15,306,418...15,336,463 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:70338|PMID:7807014) MGI
Ensembl		 PMID:7807014 GO_REF:0000107 MGI:70338 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994 		JBrowse link
G SOX13 SRY-box transcription factor 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:179,675,017...179,730,628
Ensembl chr 1:184,003,907...184,016,504 		JBrowse link
G SOX4 SRY-box transcription factor 4 involved_in ISO (MGI:5486619|PMID:23562159) UniProt PMID:23562159 MGI:5486619 NCBI chr 6:21,422,846...21,427,779 JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:77314|PMID:7477352)
(MGI:83585|PMID:8790395)		 MGI
Ensembl		 PMID:7477352 PMID:8790395 GO_REF:0000107 MGI:77314 MGI:83585 NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101 		JBrowse link
regulation of gamma-delta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EGR3 early growth response 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5139961|PMID:21737317) MGI
Ensembl		 PMID:21737317 GO_REF:0000107 MGI:5139961 NCBI chr 8:21,937,516...21,943,646
Ensembl chr 8:18,877,396...18,882,874 		JBrowse link
G RORC RAR related orphan receptor C acts_upstream_of_or_within ISO (MGI:5139961|PMID:21737317) MGI PMID:21737317 MGI:5139961 NCBI chr 1:127,164,725...127,190,479
Ensembl chr 1:130,808,705...130,834,490 		JBrowse link
G SOX13 SRY-box transcription factor 13 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5139961|PMID:21737317) MGI
Ensembl		 PMID:21737317 GO_REF:0000107 MGI:5139961 NCBI chr 1:179,675,017...179,730,628
Ensembl chr 1:184,003,907...184,016,504 		JBrowse link
G TCF7 transcription factor 7 involved_in ISO (MGI:5486619|PMID:23562159) UniProt PMID:23562159 MGI:5486619 NCBI chr 5:129,518,134...129,549,972
Ensembl chr 5:135,671,095...135,702,734 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15680
    immune system process 2246
      leukocyte activation 951
        lymphocyte activation 768
          T cell activation 536
            gamma-delta T cell activation 23
              gamma-delta T cell activation involved in immune response + 1
              gamma-delta T cell differentiation + 17
              gamma-delta T cell proliferation + 1
              negative regulation of gamma-delta T cell activation + 0
              positive regulation of gamma-delta T cell activation + 11
              regulation of gamma-delta T cell activation + 14
Path 2
Term Annotations click to browse term
  biological_process 15680
    cellular process 14662
      cell activation 1098
        leukocyte activation 951
          lymphocyte activation 768
            T cell activation 536
              gamma-delta T cell activation 23
                gamma-delta T cell activation involved in immune response + 1
                gamma-delta T cell differentiation + 17
                gamma-delta T cell proliferation + 1
                negative regulation of gamma-delta T cell activation + 0
                positive regulation of gamma-delta T cell activation + 11
                regulation of gamma-delta T cell activation + 14
paths to the root