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ONTOLOGY REPORT - ANNOTATIONS


Term:sphingolipid binding
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Accession:GO:0046625 term browser browse the term
Definition:Interacting selectively and non-covalently with sphingolipids, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).


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sphingolipid binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cerkl ceramide kinase-like ISO (MGI:MGI:5571022|PMID:23501591) RGD PMID:23501591 MGI:MGI:5571022 NCBI chr 3:66,268,835...66,395,615
Ensembl chr 3:66,268,947...66,394,764
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IPI in glomerular endothelial, but not mesangial, cells RGD PMID:15164763 RGD:2293487 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
JBrowse link
G Phb2 prohibitin 2 ISS
ISO
GO_REF:0000024
(MGI:MGI:6294409|PMID:20959514)
(PMID:20959514)
UniProt
RGD
PMID:20959514 GO_REF:0000024, MGI:MGI:6294409 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IDA RGD PMID:9765227 RGD:1581785 NCBI chr 2:218,654,406...218,658,761
Ensembl chr 2:218,654,554...218,658,761
JBrowse link
G Traf2 Tnf receptor-associated factor 2 ISO (PMID:20577214) RGD PMID:20577214 NCBI chr 3:2,746,061...2,770,690
Ensembl chr 3:2,746,075...2,770,620
JBrowse link
ceramide 1-phosphate binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cert1 ceramide transporter 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:27,365,145...27,469,797
Ensembl chr 2:27,365,148...27,469,779
JBrowse link
G Cptp ceramide-1-phosphate transfer protein ISO
IBA
ISS
(PMID:23863933)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:23863933, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:173,314,219...173,318,384
Ensembl chr 5:173,314,228...173,318,313
JBrowse link
G Gltp glycolipid transfer protein IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:47,667,556...47,687,708
Ensembl chr12:47,667,556...47,687,707
JBrowse link
G Gltpd2 glycolipid transfer protein domain containing 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:57,126,127...57,127,783
Ensembl chr10:57,125,961...57,128,686
JBrowse link
G Pla2g4a phospholipase A2 group IVA ISO
ISS
IEA
(PMID:17472963)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:17472963 GO_REF:0000024, GO_REF:0000107 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Plekha8 pleckstrin homology domain containing A8 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:84,770,294...84,820,887
Ensembl chr 4:84,770,375...84,820,887
JBrowse link
ceramide binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300lf Cd300 molecule-like family member F ISO
ISS
(PMID:24035150)
GO_REF:0000024
(MGI:MGI:5451118|PMID:23123064)
RGD
UniProt
PMID:23123064, PMID:24035150 GO_REF:0000024, MGI:MGI:5451118 NCBI chr10:103,669,781...103,690,584
Ensembl chr10:103,670,028...103,687,425
JBrowse link
G Cert1 ceramide transporter 1 ISO (PMID:14685229), (PMID:18184806) RGD PMID:14685229, PMID:18184806 NCBI chr 2:27,365,145...27,469,797
Ensembl chr 2:27,365,148...27,469,779
JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein ISO
ISS
(PMID:18317235)
GO_REF:0000024
RGD
UniProt
PMID:18317235 GO_REF:0000024 NCBI chr16:79,828,321...79,838,212
Ensembl chr16:79,828,324...79,838,212
JBrowse link
G Laptm4b lysosomal protein transmembrane 4 beta ISO
ISS
(PMID:26280656)
GO_REF:0000024
RGD
UniProt
PMID:26280656 GO_REF:0000024 NCBI chr 7:72,924,911...72,968,099
Ensembl chr 7:72,924,799...72,968,101
JBrowse link
G Plekha8 pleckstrin homology domain containing A8 ISO
ISS
(PMID:17687330)
GO_REF:0000024
RGD
UniProt
PMID:17687330 GO_REF:0000024 NCBI chr 4:84,770,294...84,820,887
Ensembl chr 4:84,770,375...84,820,887
JBrowse link
G Pltp phospholipid transfer protein ISO
IBA
(PMID:9132017)
PMID:21873635
RGD PMID:9132017, PMID:21873635 RGD:13792537 NCBI chr 3:161,304,469...161,322,289
Ensembl chr 3:161,304,469...161,322,289
JBrowse link
G Vdac1 voltage-dependent anion channel 1 ISO
IEA
(PMID:31015432)
GO_REF:0000107
RGD
Ensembl
PMID:31015432 GO_REF:0000107 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Vdac2 voltage-dependent anion channel 2 ISO
ISS
(PMID:31015432)
GO_REF:0000024
RGD
UniProt
PMID:31015432 GO_REF:0000024 NCBI chr15:2,634,622...2,648,548
Ensembl chr15:2,634,624...2,648,551
JBrowse link
ganglioside binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clip3 CAP-GLY domain containing linker protein 3 ISO
ISS
(PMID:20052288)
GO_REF:0000024
RGD
UniProt
PMID:20052288 GO_REF:0000024 NCBI chr 1:88,750,453...88,766,453
Ensembl chr 1:90,962,707...90,978,907
JBrowse link
G LOC108348122 CAP-Gly domain-containing linker protein 3 ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:90,962,921...90,978,946
Ensembl chr 1:90,962,707...90,978,907
JBrowse link
ganglioside GM1 binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epdr1 ependymin related 1 ISO
IEA
(PMID:30729188)
GO_REF:0000107
RGD
Ensembl
PMID:30729188 GO_REF:0000107 NCBI chr17:47,397,558...47,422,183
Ensembl chr17:47,397,558...47,422,182
JBrowse link
G Psap prosaposin IEA
ISO
GO_REF:0000107
(PMID:1454804)
Ensembl
RGD
PMID:1454804 GO_REF:0000107 NCBI chr20:29,831,302...29,856,876
Ensembl chr20:29,831,314...29,856,875
JBrowse link
G Rtn4r reticulon 4 receptor ISO
ISS
(PMID:18411262)
GO_REF:0000024
RGD
UniProt
PMID:18411262 GO_REF:0000024 NCBI chr11:86,992,665...87,017,091
Ensembl chr11:86,992,399...87,017,115
JBrowse link
ganglioside GM2 binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Psap prosaposin IEA
ISO
GO_REF:0000107
(PMID:1454804)
Ensembl
RGD
PMID:1454804 GO_REF:0000107 NCBI chr20:29,831,302...29,856,876
Ensembl chr20:29,831,314...29,856,875
JBrowse link
ganglioside GM3 binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Psap prosaposin IEA
ISO
GO_REF:0000107
(PMID:1454804)
Ensembl
RGD
PMID:1454804 GO_REF:0000107 NCBI chr20:29,831,302...29,856,876
Ensembl chr20:29,831,314...29,856,875
JBrowse link
ganglioside GP1c binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Psap prosaposin IEA
ISO
GO_REF:0000107
(PMID:1454804)
Ensembl
RGD
PMID:1454804 GO_REF:0000107 NCBI chr20:29,831,302...29,856,876
Ensembl chr20:29,831,314...29,856,875
JBrowse link
ganglioside GT1b binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mag myelin-associated glycoprotein IDA
ISS
ISO
PMID:8995428
GO_REF:0000024
(MGI:MGI:5822923|PMID:27922006)
UniProt
RGD
PMID:27922006, PMID:8995428 GO_REF:0000024, MGI:MGI:5822923, RGD:12050139 NCBI chr 1:89,345,325...89,360,905
Ensembl chr 1:89,345,429...89,360,733
JBrowse link
G Psap prosaposin IEA
ISO
GO_REF:0000107
(PMID:1454804)
Ensembl
RGD
PMID:1454804 GO_REF:0000107 NCBI chr20:29,831,302...29,856,876
Ensembl chr20:29,831,314...29,856,875
JBrowse link
G Rtn4r reticulon 4 receptor ISO
ISS
(PMID:18411262)
GO_REF:0000024
RGD
UniProt
PMID:18411262 GO_REF:0000024 NCBI chr11:86,992,665...87,017,091
Ensembl chr11:86,992,399...87,017,115
JBrowse link
glycosphingolipid binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cel carboxyl ester lipase IDA RGD PMID:15296737 RGD:2313559 NCBI chr 3:7,134,021...7,141,522
Ensembl chr 3:7,134,021...7,141,522
JBrowse link
G Il2 interleukin 2 IDA binds gangliosides GM1, GD1a, GD1b and GT1b with increased binding as the carbohydrate side chains increase in complexity RGD PMID:6609839 RGD:1600093 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Lama1 laminin subunit alpha 1 ISO (MGI:MGI:3836888|PMID:19118221) RGD PMID:19118221 MGI:MGI:3836888 NCBI chr 9:115,916,907...116,042,123
Ensembl chr 9:115,916,907...116,042,123
JBrowse link
G Lamb1 laminin subunit beta 1 ISO (MGI:MGI:3836888|PMID:19118221) RGD PMID:19118221 MGI:MGI:3836888 NCBI chr 6:50,528,796...50,596,593
Ensembl chr 6:50,528,823...50,596,079
JBrowse link
G Lamc1 laminin subunit gamma 1 ISO (MGI:MGI:3836888|PMID:19118221) RGD PMID:19118221 MGI:MGI:3836888 NCBI chr13:70,656,727...70,783,515
Ensembl chr13:70,658,707...70,783,515
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IPI RGD PMID:8106508 RGD:2303724 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20455
    binding 17199
      lipid binding 806
        sphingolipid binding 29
          ceramide binding + 18
          glycosphingolipid binding + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.