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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of organ growth
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Accession:GO:0046621 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.



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negative regulation of organ growth term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd26 ankyrin repeat domain containing 26 acts_upstream_of_or_within ISO MGI:3774418 (PMID:18162531) RGD PMID:18162531 NCBI chr 4:151,670,604...151,740,032
Ensembl chr 4:151,672,037...151,739,968
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide acts_upstream_of_or_within ISO MGI:1857152 (PMID:12114718) RGD PMID:12114718 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
JBrowse link
G Fxn frataxin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2177175|MGI:2177176 (PMID:9405681)
Ensembl
RGD
PMID:9405681 GO_REF:0000107 NCBI chr 1:221,874,007...221,897,543
Ensembl chr 1:221,872,420...221,897,540
JBrowse link
G Men1 menin 1 acts_upstream_of_or_within ISO (PMID:17975067) RGD PMID:17975067 NCBI chr 1:203,638,905...203,644,871
Ensembl chr 1:203,639,000...203,644,871
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (MGI:3832995|PMID:19208814) RGD PMID:19208814 MGI:3832995 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptk2 protein tyrosine kinase 2 acts_upstream_of_or_within ISO MGI:87963 (PMID:16374517) RGD PMID:16374517 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Slc6a4 solute carrier family 6 member 4 involved_in ISO (MGI:3832995|PMID:19208814) RGD PMID:19208814 MGI:3832995 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Stk3 serine/threonine kinase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1929004 (PMID:20080598)
Ensembl
RGD
PMID:20080598 GO_REF:0000107 NCBI chr 7:66,053,209...66,323,292
Ensembl chr 7:66,052,345...66,323,233
JBrowse link
G Stk4 serine/threonine kinase 4 acts_upstream_of_or_within ISO MGI:1928487 (PMID:20080598) RGD PMID:20080598 NCBI chr 3:152,745,958...152,827,747
Ensembl chr 3:152,745,681...152,827,744
JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO MGI:1926344 (PMID:17919533) RGD PMID:17919533 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
G Wwc1 WW and C2 domain containing 1 involved_in ISO
IBA
(PMID:24682284)
GO_REF:0000033
RGD
GO_Central
PMID:24682284 GO_REF:0000033 NCBI chr10:20,300,735...20,454,393
Ensembl chr10:20,300,833...20,454,497
JBrowse link
G Wwc2 WW and C2 domain containing 2 involved_in ISO
IBA
(PMID:24682284)
GO_REF:0000033
RGD
GO_Central
PMID:24682284 GO_REF:0000033 NCBI chr16:44,258,372...44,421,815
Ensembl chr16:44,258,372...44,421,812
JBrowse link
G Wwc3 WWC family member 3 involved_in ISO
IBA
(PMID:24682284)
GO_REF:0000033
RGD
GO_Central
PMID:24682284 GO_REF:0000033 NCBI chr  X:23,584,204...23,701,864
Ensembl chr  X:23,584,424...23,700,513
JBrowse link
negative regulation of cardiac muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in IMP PMID:28948298 BHF-UCL PMID:28948298 RGD:13464260 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 involved_in IMP PMID:26240138 BHF-UCL PMID:26240138 RGD:13210532 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Cxadr CXADR, Ig-like cell adhesion molecule acts_upstream_of_or_within ISO MGI:3711226 (PMID:16543498) RGD PMID:16543498 NCBI chr11:16,982,864...17,030,078
Ensembl chr11:16,982,860...17,030,046
JBrowse link
G Gja1 gap junction protein, alpha 1 IMP RGD PMID:19377854 RGD:7207421 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within ISO MGI:3712002 (PMID:17322895) RGD PMID:17322895 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 involved_in
acts_upstream_of_or_within
IMP
ISO
IDA
PMID:26298346
MGI:1856923 (PMID:15870077)
RGD PMID:15870077 PMID:26298346 PMID:26298346 RGD:11522645, RGD:11522645 NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 IMP RGD PMID:24705172 RGD:9831164 NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 acts_upstream_of_or_within ISO MGI:3609429 (PMID:21768366) RGD PMID:21768366 NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395
JBrowse link
G Mir1 microRNA 1 acts_upstream_of_or_within ISO (PMID:17397913) RGD PMID:17397913 NCBI chr18:1,887,537...1,887,623 JBrowse link
G Mir873 microRNA 873 involved_in ISO (PMID:28583401) RGD PMID:28583401 NCBI chr 5:51,356,919...51,356,995
Ensembl chr 5:51,356,919...51,356,995
JBrowse link
G Nog noggin involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:3783944|PMID:17218603)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:17218603 GO_REF:0000024 GO_REF:0000107 MGI:3783944 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO
IMP
RNAcentral:URS000006FDD4_10090|RNAcentral:URS000013D17D_10090 (MGI:5584062|PMID:23575307) RGD PMID:23575307 PMID:30783439 MGI:5584062, RGD:150527846 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Rbp4 retinol binding protein 4 involved_in ISO (MGI:2655947|PMID:12663486) RGD PMID:12663486 MGI:2655947 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
JBrowse link
G Sav1 salvador family WW domain containing protein 1 acts_upstream_of_or_within ISO MGI:2654594|MGI:4430538 (PMID:21512031) RGD PMID:21512031 NCBI chr 6:88,478,536...88,500,121
Ensembl chr 6:88,478,539...88,499,968
JBrowse link
G Tbx5 T-box transcription factor 5 involved_in ISO
IEA
ISS
(PMID:11161571)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:11161571 GO_REF:0000024 GO_REF:0000107 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 IMP RGD PMID:15537505 RGD:1601597 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO (PMID:18634800) RGD PMID:18634800 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
G Vgll4 vestigial-like family member 4 involved_in ISO (MGI:6120600|PMID:27720608) RGD PMID:27720608 MGI:6120600 NCBI chr 4:147,925,630...148,038,519
Ensembl chr 4:147,927,034...148,038,471
JBrowse link
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 IMP RGD PMID:21170593 RGD:6784534 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Ctdp1 CTD phosphatase subunit 1 IMP RGD PMID:22569295 RGD:9686371 NCBI chr18:73,854,277...73,916,232
Ensembl chr18:73,854,282...73,916,457
JBrowse link
G Foxp1 forkhead box P1 IMP RGD PMID:26333362 RGD:11561912 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IMP RGD PMID:24190878 RGD:10449133 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO
IEA
(MGI:4829580|PMID:20516643)
GO_REF:0000107
RGD
Ensembl
PMID:20516643 GO_REF:0000107 MGI:4829580 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Mir451a microRNA 451a IMP RGD PMID:25209900 RGD:11558015 NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IMP RGD PMID:22082674 RGD:11533929 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383
JBrowse link
G Pi16 peptidase inhibitor 16 acts_upstream_of_or_within ISO (PMID:17909105) RGD PMID:17909105 NCBI chr20:7,376,073...7,385,386
Ensembl chr20:7,376,126...7,385,383
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IMP RGD PMID:22198280 RGD:5687133 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Rbm10 RNA binding motif protein 10 IMP RGD PMID:30257214 RGD:151667449 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575
JBrowse link
G Rgs2 regulator of G-protein signaling 2 IMP RGD PMID:16380388 RGD:13524577 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rgs4 regulator of G-protein signaling 4 IDA RGD PMID:9918533 RGD:7207376 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 IMP RGD PMID:25022898 RGD:13464131 NCBI chr11:43,378,719...43,417,166
Ensembl chr11:43,377,216...43,417,202
JBrowse link
G Yy1 YY1 transcription factor IMP RGD PMID:18632988 RGD:9588273 NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747
JBrowse link
G Zfp418 zinc finger protein 418 acts_upstream_of_or_within ISO (PMID:29065170) RGD PMID:29065170 NCBI chr 1:66,581,406...66,594,247
Ensembl chr 1:66,581,287...66,594,242
JBrowse link
negative regulation of growth plate cartilage chondrocyte proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within ISO MGI:2653208 (PMID:26972716) RGD PMID:26972716 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19872
    multicellular organismal process 8843
      negative regulation of multicellular organismal process 1361
        negative regulation of organ growth 46
          negative regulation of growth plate cartilage chondrocyte proliferation 1
          negative regulation of heart growth + 33
Path 2
Term Annotations click to browse term
  biological_process 19872
    biological regulation 13396
      regulation of biological process 12998
        regulation of growth 684
          regulation of developmental growth 403
            regulation of organ growth 131
              negative regulation of organ growth 46
                negative regulation of growth plate cartilage chondrocyte proliferation 1
                negative regulation of heart growth + 33
paths to the root