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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of centrosome cycle
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Accession:GO:0046606 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the centrosome cycle.
Synonyms:exact_synonym: down regulation of centrosome cycle;   downregulation of centrosome cycle
 narrow_synonym: inhibition of centrosome cycle


show annotations for term's descendants           Sort by:
negative regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(MGI:4830038|PMID:20627074)
GO_REF:0000118
GO_REF:0000033		 UniProt
Ensembl
RGD
TreeGrafter
GO_Central		 PMID:20627074 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:4830038 NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782 		JBrowse link
G Kat2a lysine acetyltransferase 2A involved_in ISO (PMID:27796307) RGD PMID:27796307 NCBI chr10:85,632,216...85,640,561
Ensembl chr10:85,632,216...85,640,166 		JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO (PMID:27796307) RGD PMID:27796307 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Mdm1 Mdm1 nuclear protein involved_in IEA
ISO
ISS		 GO_REF:0000002
(PMID:26337392)
GO_REF:0000024		 InterPro
RGD
UniProt		 PMID:26337392 GO_REF:0000002 GO_REF:0000024 NCBI chr 7:53,729,603...53,766,034
Ensembl chr 7:53,729,610...53,766,034 		JBrowse link
G Rbm14 RNA binding motif protein 14 involved_in ISO (PMID:25385835) RGD PMID:25385835 NCBI chr 1:202,076,940...202,105,688
Ensembl chr 1:202,078,287...202,105,665 		JBrowse link
G Trim37 tripartite motif-containing 37 involved_in ISO
IBA		 (PMID:23769972)
GO_REF:0000033		 RGD
GO_Central		 PMID:23769972 GO_REF:0000033 NCBI chr10:71,943,384...72,075,563
Ensembl chr10:71,943,375...72,075,558 		JBrowse link
negative regulation of centrosome duplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnf cyclin F involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:20596027)		 UniProt
RGD		 PMID:20596027 GO_REF:0000024 NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101 		JBrowse link
G Cenatac centrosomal AT-AC splicing factor involved_in ISO (PMID:31722219), (PMID:34009673) RGD PMID:31722219 PMID:34009673 NCBI chr 8:44,735,968...44,742,859
Ensembl chr 8:44,735,972...44,742,837 		JBrowse link
G Kifc1 kinesin family member C1 acts_upstream_of_or_within ISO (PMID:16638812) RGD PMID:16638812 NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105 		JBrowse link
G Npm1 nucleophosmin 1 involved_in ISO (PMID:16041368) RGD PMID:16041368 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G Nubp1 NUBP iron-sulfur cluster assembly factor 1 acts_upstream_of_or_within ISO (PMID:16638812), (PMID:23028652) RGD PMID:16638812 PMID:23028652 NCBI chr10:5,259,328...5,270,848 JBrowse link
G Tmem67 transmembrane protein 67 involved_in IMP
ISO
IEA		 (MGI:4353840|PMID:19515853)
GO_REF:0000107
(PMID:19515853)		 RGD
Ensembl		 PMID:19515853 PMID:19515853 GO_REF:0000107 MGI:4353840, RGD:8554306 NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cell cycle process 1350
        centrosome cycle 151
          negative regulation of centrosome cycle 12
            negative regulation of centrosome duplication + 12
Path 2
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cellular component organization or biogenesis 7290
        cellular component organization 6980
          organelle organization 3887
            cytoskeleton organization 1643
              microtubule cytoskeleton organization 746
                microtubule organizing center organization 166
                  centrosome cycle 151
                    regulation of centrosome cycle 61
                      negative regulation of centrosome cycle 12
                        negative regulation of centrosome duplication + 12
paths to the root