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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of centrosome cycle
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Accession:GO:0046605 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation.


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regulation of centrosome cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf5 activating transcription factor 5 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:26213385)
UniProt
Ensembl
RGD
PMID:26213385 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 IDA RGD PMID:10545494 RGD:70723 NCBI chr 8:122,743,274...122,776,801
Ensembl chr 8:122,743,189...122,776,806
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IMP RGD PMID:24388750 RGD:10047173 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mark4 microtubule affinity regulating kinase 4 involved_in ISO (PMID:25123532) RGD PMID:25123532 NCBI chr 1:80,335,517...80,367,366
Ensembl chr 1:80,335,526...80,367,328
JBrowse link
G Mcph1 microcephalin 1 acts_upstream_of_or_within ISO MGI:5308745 (MGI:5306866|PMID:21947081) RGD PMID:21947081 MGI:5306866 NCBI chr16:75,904,087...76,110,624
Ensembl chr16:75,904,006...76,110,553
JBrowse link
G Wdr62 WD repeat domain 62 IMP RGD PMID:24388750 RGD:10047173 NCBI chr 1:90,995,545...91,034,592
Ensembl chr 1:88,694,824...88,734,223
JBrowse link
negative regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:4830038|PMID:20627074)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:20627074 GO_REF:0000024 GO_REF:0000107 MGI:4830038 NCBI chr 5:86,387,238...86,554,108
Ensembl chr 5:86,387,078...86,554,102
JBrowse link
G Kat2a lysine acetyltransferase 2A involved_in ISO (PMID:27796307) RGD PMID:27796307 NCBI chr10:88,611,586...88,619,558
Ensembl chr10:88,611,586...88,619,537
JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO (PMID:27796307) RGD PMID:27796307 NCBI chr 9:4,440,982...4,492,949 JBrowse link
G Mdm1 Mdm1 nuclear protein involved_in IEA
ISO
ISS
GO_REF:0000002
(PMID:26337392)
GO_REF:0000024
InterPro
RGD
UniProt
PMID:26337392 GO_REF:0000002 GO_REF:0000024 NCBI chr 7:61,165,652...61,200,865
Ensembl chr 7:61,165,640...61,200,879
JBrowse link
G Rbm14 RNA binding motif protein 14 involved_in ISO (PMID:25385835) RGD PMID:25385835 NCBI chr 1:220,048,740...220,067,124
Ensembl chr 1:220,048,873...220,067,124
JBrowse link
G Trim37 tripartite motif-containing 37 involved_in ISO
IBA
(PMID:23769972)
PMID:21873635
RGD PMID:23769972, PMID:21873635 RGD:13792537 NCBI chr10:74,436,165...74,568,636
Ensembl chr10:74,436,208...74,568,493
JBrowse link
negative regulation of centrosome duplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnf cyclin F involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:4819440|PMID:20596027)
(PMID:20596027)
UniProt
RGD
PMID:20596027 GO_REF:0000024 MGI:4819440 NCBI chr10:13,594,687...13,619,935
Ensembl chr10:13,594,687...13,619,935
JBrowse link
G Cenatac centrosomal AT-AC splicing factor involved_in ISO (PMID:31722219) RGD PMID:31722219 NCBI chr 8:48,729,695...48,736,574
Ensembl chr 8:48,729,835...48,736,506
JBrowse link
G Npm1 nucleophosmin 1 involved_in ISO (PMID:16041368) RGD PMID:16041368 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950
JBrowse link
G Nubp1 nucleotide binding protein 1 acts_upstream_of_or_within ISO (MGI:3625381|PMID:16638812), (MGI:5463135|PMID:23028652) RGD PMID:16638812 PMID:23028652 MGI:3625381 MGI:5463135 NCBI chr10:5,333,378...5,343,949
Ensembl chr10:5,333,378...5,344,121
JBrowse link
G Tmem67 transmembrane protein 67 involved_in IMP
ISO
IEA
(MGI:4353840|PMID:19515853)
GO_REF:0000107
(PMID:19515853)
RGD
Ensembl
PMID:19515853, PMID:19515853 GO_REF:0000107 MGI:4353840, RGD:8554306 NCBI chr 5:25,666,138...25,721,056
Ensembl chr 5:25,666,137...25,721,072
JBrowse link
positive regulation of centriole elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpj centromere protein J involved_in ISO (PMID:27185865) RGD PMID:27185865 NCBI chr15:36,745,672...36,809,228
Ensembl chr15:36,746,088...36,798,814
JBrowse link
G Cep120 centrosomal protein 120 involved_in ISO
IBA
(PMID:27185865)
PMID:21873635
RGD PMID:27185865, PMID:21873635 RGD:13792537 NCBI chr18:48,658,495...48,720,570
Ensembl chr18:48,658,495...48,720,472
JBrowse link
G Cep295 centrosomal protein 295 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:27185865)
Ensembl
UniProt
RGD
PMID:27185865 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:13,871,065...13,909,249
Ensembl chr 8:13,871,213...13,909,188
JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr13:26,825,261...26,850,460
Ensembl chr13:26,825,261...26,850,460
JBrowse link
positive regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nup62 nucleoporin 62 involved_in ISO (PMID:24107630) RGD PMID:24107630 NCBI chr 1:100,811,140...100,827,119
Ensembl chr 1:100,811,755...100,827,111
JBrowse link
G Plk4 polo-like kinase 4 involved_in ISO
ISS
(PMID:16244668), (PMID:17681131), (PMID:22349705), (PMID:27796307)
GO_REF:0000024
RGD
UniProt
PMID:16244668 PMID:17681131 PMID:22349705 PMID:27796307 GO_REF:0000024 NCBI chr 2:127,686,911...127,705,518
Ensembl chr 2:127,686,925...127,705,518
JBrowse link
positive regulation of centrosome duplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin1 antizyme inhibitor 1 IMP RGD PMID:17667942 RGD:14700805 NCBI chr 7:77,345,646...77,372,398
Ensembl chr 7:77,345,646...77,372,398
JBrowse link
G Cep120 centrosomal protein 120 involved_in ISO (MGI:5635753|PMID:25251415) RGD PMID:25251415 MGI:5635753 NCBI chr18:48,658,495...48,720,570
Ensembl chr18:48,658,495...48,720,472
JBrowse link
G Cep295 centrosomal protein 295 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:25131205)
Ensembl
UniProt
RGD
PMID:25131205 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:13,871,065...13,909,249
Ensembl chr 8:13,871,213...13,909,188
JBrowse link
G Npm1 nucleophosmin 1 acts_upstream_of_or_within ISO UniProtKB:Q28201 (MGI:3697024|PMID:17015463) RGD PMID:17015463 MGI:3697024 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950
JBrowse link
G Poc1a POC1 centriolar protein A acts_upstream_of_or_within ISO MGI:2135614 (MGI:5700251|PMID:26496357) RGD PMID:26496357 MGI:5700251 NCBI chr 8:114,982,764...115,050,844
Ensembl chr 8:114,986,326...115,050,728
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000002
(MGI:3697024|PMID:17015463)
InterPro
RGD
PMID:17015463 GO_REF:0000002 MGI:3697024 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908
JBrowse link
regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alms1 ALMS1, centrosome and basal body associated protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:117,371,544...117,472,310
Ensembl chr 4:117,371,659...117,472,198
JBrowse link
G Cenpj centromere protein J involved_in ISO (PMID:20531387) RGD PMID:20531387 NCBI chr15:36,745,672...36,809,228
Ensembl chr15:36,746,088...36,798,814
JBrowse link
G Cep295 centrosomal protein 295 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:13,871,065...13,909,249
Ensembl chr 8:13,871,213...13,909,188
JBrowse link
G Cep295nl CEP295 N-terminal like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:107,363,511...107,381,280
Ensembl chr10:107,363,511...107,376,645
JBrowse link
G Cep76 centrosomal protein 76 involved_in ISO (PMID:19460342) RGD PMID:19460342 NCBI chr18:63,364,990...63,394,766
Ensembl chr18:63,359,832...63,394,766
JBrowse link
G LOC100302465 hypothetical LOC100302465 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:206,324,763...206,417,143
Ensembl chr 1:206,324,765...206,417,143
JBrowse link
G Npm1 nucleophosmin 1 involved_in ISO
ISS
(PMID:20352051)
GO_REF:0000024
RGD
UniProt
PMID:20352051 GO_REF:0000024 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950
JBrowse link
G Plk2 polo-like kinase 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:15242618), (PMID:19001868), (PMID:20352051), (PMID:20531387)
UniProt
RGD
PMID:15242618 PMID:19001868 PMID:20352051 PMID:20531387 GO_REF:0000024 NCBI chr 2:41,911,143...41,916,901
Ensembl chr 2:41,911,131...41,916,901
JBrowse link
G Spice1 spindle and centriole associated protein 1 involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:20736305)
UniProt
RGD
PMID:20736305, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:61,250,649...61,294,116
Ensembl chr11:61,251,696...61,294,022
JBrowse link
G Stil STIL, centriolar assembly protein involved_in ISO (PMID:22020124) RGD PMID:22020124 NCBI chr 5:133,819,302...133,851,362
Ensembl chr 5:133,819,726...133,851,416
JBrowse link
regulation of centrosome duplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07007744.2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 2:26,869,828...26,870,421 JBrowse link
G AABR07025089.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr16:28,072,014...28,166,296 JBrowse link
G AABR07041089.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr  X:118,996,333...118,998,300 JBrowse link
G AABR07055527.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 7:4,951,747...4,952,584 JBrowse link
G AABR07067023.1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 9:26,636,334...26,707,571 JBrowse link
G AABR07067024.1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 9:26,727,162...26,734,763 JBrowse link
G Cep131 centrosomal protein 131 involved_in IBA
ISO
PMID:21873635
(PMID:22797915)
RGD PMID:22797915, PMID:21873635 RGD:13792537 NCBI chr10:109,243,240...109,267,636
Ensembl chr10:109,243,039...109,267,500
JBrowse link
G Chmp1a charged multivesicular body protein 1A involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr19:56,001,724...56,010,004
Ensembl chr19:56,001,724...56,010,004
JBrowse link
G Chmp1b charged multivesicular body protein 1B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr18:62,923,620...62,926,150 JBrowse link
G Chmp2a charged multivesicular body protein 2A involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 1:65,540,808...65,543,708
Ensembl chr 1:65,541,322...65,543,707
JBrowse link
G Chmp2b charged multivesicular body protein 2B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr11:2,666,405...2,692,213
Ensembl chr11:2,665,285...2,692,198
JBrowse link
G Chmp3 charged multivesicular body protein 3 involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 4:99,449,213...99,496,156
Ensembl chr 4:99,449,111...99,494,423
JBrowse link
G Chmp4b charged multivesicular body protein 4B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 3:150,188,275...150,227,453
Ensembl chr 3:150,188,455...150,227,405
JBrowse link
G Chmp4c charged multivesicular body protein 4C involved_in ISO
IEA
(PMID:20616062)
GO_REF:0000107
RGD
Ensembl
PMID:20616062 GO_REF:0000107 NCBI chr 2:93,574,554...93,641,497
Ensembl chr 2:93,574,559...93,641,497
JBrowse link
G Chmp5 charged multivesicular body protein 5 involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 5:57,267,312...57,284,455
Ensembl chr 5:57,267,312...57,284,448
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:4441223|PMID:20230755)
UniProt
RGD
PMID:20230755 GO_REF:0000024 MGI:4441223 NCBI chr 8:17,421,552...17,445,513
Ensembl chr 8:17,421,557...17,446,165
JBrowse link
G Fbxw5 F-box and WD repeat domain containing 5 involved_in ISO
ISS
(PMID:21725316)
GO_REF:0000024
RGD
UniProt
PMID:21725316 GO_REF:0000024 NCBI chr 3:2,726,705...2,731,213
Ensembl chr 3:2,727,254...2,731,212
JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease involved_in ISO (PMID:23108668), (PMID:23166748) RGD PMID:23108668 PMID:23166748 NCBI chr 6:36,910,064...36,940,868
Ensembl chr 6:36,910,675...36,940,868
JBrowse link
G Nat10 N-acetyltransferase 10 involved_in ISO (PMID:31722219) RGD PMID:31722219 NCBI chr 3:93,658,119...93,698,136
Ensembl chr 3:93,658,117...93,698,136
JBrowse link
G Npm1 nucleophosmin 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3604807 (MGI:3604166|PMID:16007073)
RGD PMID:16007073, PMID:21873635 MGI:3604166, RGD:13792537 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950
JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 8:121,916,233...121,973,145
Ensembl chr 8:121,916,185...121,973,125
JBrowse link
G Pkhd1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin involved_in ISO (PMID:20554582) RGD PMID:20554582 NCBI chr 9:26,164,969...26,736,704 JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:31722219)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:31722219 GO_REF:0000024 GO_REF:0000107 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr13:26,825,261...26,850,460
Ensembl chr13:26,825,261...26,850,460
JBrowse link
G Xpo1 exportin 1 acts_upstream_of_or_within ISO (MGI:3610707|PMID:16297385) RGD PMID:16297385 MGI:3610707 NCBI chr14:108,007,421...108,049,088
Ensembl chr14:108,007,724...108,049,660
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO (PMID:23108668) RGD PMID:23108668 NCBI chr 6:136,366,917...136,380,751
Ensembl chr 6:136,371,555...136,379,348
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19634
    cellular process 18481
      cell cycle process 1165
        centrosome cycle 137
          regulation of centrosome cycle 57
            negative regulation of centrosome cycle + 11
            positive regulation of centrosome cycle 0
            regulation of centrosome duplication + 51
Path 2
Term Annotations click to browse term
  biological_process 19634
    cellular process 18481
      cellular component organization or biogenesis 6713
        cellular component organization 6470
          organelle organization 4057
            cytoskeleton organization 1443
              microtubule cytoskeleton organization 634
                microtubule organizing center organization 149
                  centrosome cycle 137
                    regulation of centrosome cycle 57
                      negative regulation of centrosome cycle + 11
                      positive regulation of centrosome cycle 0
                      regulation of centrosome duplication + 51
paths to the root