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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of centrosome cycle
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Accession:GO:0046605 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation.
Synonyms:never_in_taxon: NCBITaxon:27896 ! Planariidae;   NCBITaxon:33090 ! Viridiplantae;   NCBITaxon:4751 ! Fungi


show annotations for term's descendants           Sort by:
regulation of centrosome cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf5 activating transcription factor 5 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:26213385)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:26213385 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707 		JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 IDA RGD PMID:10545494 RGD:70723 NCBI chr 8:114,376,649...114,410,297
Ensembl chr 8:114,376,662...114,410,934 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IMP RGD PMID:24388750 RGD:10047173 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mark4 microtubule affinity regulating kinase 4 involved_in ISO (PMID:25123532) RGD PMID:25123532 NCBI chr 1:79,075,353...79,108,882
Ensembl chr 1:79,068,904...79,108,556 		JBrowse link
G Mcph1 microcephalin 1 acts_upstream_of_or_within ISO MGI:5308745 (MGI:5306866|PMID:21947081) RGD PMID:21947081 MGI:5306866 NCBI chr16:71,021,855...71,224,067
Ensembl chr16:71,024,588...71,224,122 		JBrowse link
G Wdr62 WD repeat domain 62 IMP RGD PMID:24388750 RGD:10047173 NCBI chr 1:85,491,531...85,530,643
Ensembl chr 1:85,491,533...85,530,637 		JBrowse link
negative regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 involved_in ISS
IBA
ISO
IEA		 GO_REF:0000024
PMID:21873635
(MGI:4830038|PMID:20627074)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:20627074 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:4830038, RGD:13792537 NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782 		JBrowse link
G Kat2a lysine acetyltransferase 2A involved_in ISO (PMID:27796307) RGD PMID:27796307 NCBI chr10:85,632,216...85,640,561
Ensembl chr10:85,632,216...85,640,166 		JBrowse link
G Kat2b lysine acetyltransferase 2B involved_in ISO (PMID:27796307) RGD PMID:27796307 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Mdm1 Mdm1 nuclear protein involved_in IEA
ISS
ISO		 GO_REF:0000002
GO_REF:0000024
(PMID:26337392)		 InterPro
UniProt
RGD		 PMID:26337392 GO_REF:0000002 GO_REF:0000024 NCBI chr 7:53,729,603...53,766,034
Ensembl chr 7:53,729,610...53,766,034 		JBrowse link
G Rbm14 RNA binding motif protein 14 involved_in ISO (PMID:25385835) RGD PMID:25385835 NCBI chr 1:202,076,940...202,105,688
Ensembl chr 1:202,078,287...202,105,665 		JBrowse link
G Trim37 tripartite motif-containing 37 involved_in ISO
IBA		 (PMID:23769972)
PMID:21873635		 RGD PMID:23769972 PMID:21873635 RGD:13792537 NCBI chr10:71,943,384...72,075,563
Ensembl chr10:71,943,375...72,075,558 		JBrowse link
negative regulation of centrosome duplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnf cyclin F involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(MGI:4819440|PMID:20596027)
(PMID:20596027)		 UniProt
RGD		 PMID:20596027 GO_REF:0000024 MGI:4819440 NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101 		JBrowse link
G Cenatac centrosomal AT-AC splicing factor involved_in ISO (PMID:31722219), (PMID:34009673) RGD PMID:31722219 PMID:34009673 NCBI chr 8:44,735,968...44,742,859
Ensembl chr 8:44,735,972...44,742,837 		JBrowse link
G Kifc1 kinesin family member C1 acts_upstream_of_or_within ISO (MGI:3625381|PMID:16638812) RGD PMID:16638812 MGI:3625381 NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105 		JBrowse link
G Npm1 nucleophosmin 1 involved_in ISO (PMID:16041368) RGD PMID:16041368 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G Nubp1 NUBP iron-sulfur cluster assembly factor 1 acts_upstream_of_or_within ISO (MGI:3625381|PMID:16638812), (MGI:5463135|PMID:23028652) RGD PMID:16638812 PMID:23028652 MGI:3625381 MGI:5463135 NCBI chr10:5,259,328...5,270,848 JBrowse link
G Tmem67 transmembrane protein 67 involved_in IMP
ISO
IEA		 (MGI:4353840|PMID:19515853)
GO_REF:0000107
(PMID:19515853)		 RGD
Ensembl		 PMID:19515853 PMID:19515853 GO_REF:0000107 MGI:4353840, RGD:8554306 NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334 		JBrowse link
positive regulation of centriole elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpj centromere protein J involved_in ISO (PMID:27185865) RGD PMID:27185865 NCBI chr15:30,627,206...30,690,384
Ensembl chr15:30,627,224...30,686,791 		JBrowse link
G Cep120 centrosomal protein 120 involved_in ISO
IBA		 (PMID:27185865)
PMID:21873635		 RGD PMID:27185865 PMID:21873635 RGD:13792537 NCBI chr18:47,127,979...47,189,964
Ensembl chr18:47,127,981...47,189,964 		JBrowse link
G Cep295 centrosomal protein 295 involved_in ISO
ISS
IEA		 (PMID:27185865)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:27185865 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:12,156,568...12,194,542
Ensembl chr 8:12,156,554...12,194,552 		JBrowse link
G Ppp1r35 protein phosphatase 1, regulatory subunit 35 involved_in ISO (PMID:30168418) RGD PMID:30168418 NCBI chr12:18,915,909...18,919,253 JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr13:22,907,105...22,932,200
Ensembl chr13:22,907,109...22,932,229 		JBrowse link
positive regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpj centromere protein J involved_in ISO (PMID:22020124) RGD PMID:22020124 NCBI chr15:30,627,206...30,690,384
Ensembl chr15:30,627,224...30,686,791 		JBrowse link
G Nup62 nucleoporin 62 involved_in ISO (PMID:24107630) RGD PMID:24107630 NCBI chr 1:95,298,995...95,314,902
Ensembl chr 1:95,295,526...95,315,174 		JBrowse link
G Plk4 polo-like kinase 4 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:22349705)
(PMID:16244668), (PMID:17681131), (PMID:27796307)		 UniProt
Ensembl
RGD		 PMID:16244668 PMID:17681131 PMID:22349705 PMID:27796307 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:123,802,527...123,820,942
Ensembl chr 2:123,802,512...123,820,942 		JBrowse link
G Sass6 SAS-6 centriolar assembly protein involved_in ISO (PMID:22020124) RGD PMID:22020124 NCBI chr 2:204,546,660...204,578,930
Ensembl chr 2:204,546,660...204,578,927 		JBrowse link
G Stil STIL, centriolar assembly protein involved_in ISO (PMID:22020124) RGD PMID:22020124 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730 		JBrowse link
positive regulation of centrosome duplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Azin1 antizyme inhibitor 1 IMP RGD PMID:17667942 RGD:14700805 NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578 		JBrowse link
G Cep120 centrosomal protein 120 involved_in ISO (MGI:5635753|PMID:25251415) RGD PMID:25251415 MGI:5635753 NCBI chr18:47,127,979...47,189,964
Ensembl chr18:47,127,981...47,189,964 		JBrowse link
G Cep295 centrosomal protein 295 involved_in ISO
IEA
ISS		 (PMID:25131205)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:25131205 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:12,156,568...12,194,542
Ensembl chr 8:12,156,554...12,194,552 		JBrowse link
G Npm1 nucleophosmin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 UniProtKB:Q28201 (MGI:3697024|PMID:17015463)
GO_REF:0000107		 RGD
Ensembl		 PMID:17015463 GO_REF:0000107 MGI:3697024 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G Poc1a POC1 centriolar protein A acts_upstream_of_or_within ISO MGI:2135614 (MGI:5700251|PMID:26496357) RGD PMID:26496357 MGI:5700251 NCBI chr 8:106,922,058...106,991,678
Ensembl chr 8:106,922,978...106,991,089 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000002
(MGI:3697024|PMID:17015463)		 InterPro
RGD		 PMID:17015463 GO_REF:0000002 MGI:3697024 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alms1 ALMS1, centrosome and basal body associated protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:118,125,581...118,226,005
Ensembl chr 4:118,125,607...118,226,005 		JBrowse link
G C1h10orf90 similar to human chromosome 10 open reading frame 90 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:189,059,744...189,293,353
Ensembl chr 1:189,059,746...189,293,435 		JBrowse link
G Cenpj centromere protein J involved_in ISO (PMID:20531387) RGD PMID:20531387 NCBI chr15:30,627,206...30,690,384
Ensembl chr15:30,627,224...30,686,791 		JBrowse link
G Cep295 centrosomal protein 295 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:12,156,568...12,194,542
Ensembl chr 8:12,156,554...12,194,552 		JBrowse link
G Cep295nl CEP295 N-terminal like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:103,562,190...103,581,183
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Cep76 centrosomal protein 76 involved_in ISO
IBA		 (PMID:19460342)
PMID:21873635		 RGD PMID:19460342 PMID:21873635 RGD:13792537 NCBI chr18:61,174,514...61,208,512
Ensembl chr18:61,178,310...61,208,504 		JBrowse link
G Npm1 nucleophosmin 1 involved_in ISO
ISS		 (PMID:20352051)
GO_REF:0000024		 RGD
UniProt		 PMID:20352051 GO_REF:0000024 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G Plk2 polo-like kinase 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15242618), (PMID:19001868), (PMID:20352051), (PMID:20531387)		 UniProt
Ensembl
RGD		 PMID:15242618 PMID:19001868 PMID:20352051 PMID:20531387 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Spice1 spindle and centriole associated protein 1 involved_in IBA
ISS		 PMID:21873635
GO_REF:0000024		 UniProt PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:56,289,291...56,332,382
Ensembl chr11:56,290,540...56,332,447 		JBrowse link
G Stil STIL, centriolar assembly protein involved_in ISO (PMID:22020124) RGD PMID:22020124 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
regulation of centrosome duplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07007744.2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 2:27,601,232...27,601,825 JBrowse link
G AABR07025089.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr16:26,091,905...26,186,434 JBrowse link
G AABR07055527.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 7:4,352,572...4,353,409 JBrowse link
G Cep131 centrosomal protein 131 involved_in IBA
ISO		 PMID:21873635
(PMID:22797915)		 RGD PMID:22797915 PMID:21873635 RGD:13792537 NCBI chr10:105,346,015...105,370,380
Ensembl chr10:105,346,015...105,370,380 		JBrowse link
G Chmp1a charged multivesicular body protein 1A involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr19:51,238,153...51,246,433
Ensembl chr19:51,238,160...51,246,436 		JBrowse link
G Chmp1b charged multivesicular body protein 1B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr18:60,740,349...60,742,879 JBrowse link
G Chmp2a charged multivesicular body protein 2A involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 1:73,660,045...73,662,894
Ensembl chr 1:73,660,046...73,662,452 		JBrowse link
G Chmp2b charged multivesicular body protein 2B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr11:3,337,478...3,364,015
Ensembl chr11:3,337,494...3,385,181 		JBrowse link
G Chmp3 charged multivesicular body protein 3 involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 4:103,576,453...103,622,566
Ensembl chr 4:103,576,515...103,623,959 		JBrowse link
G Chmp4b charged multivesicular body protein 4B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 3:143,170,859...143,211,376
Ensembl chr 3:143,170,902...143,210,844 		JBrowse link
G Chmp4c charged multivesicular body protein 4C involved_in ISO
IEA		 (PMID:20616062)
GO_REF:0000107		 RGD
Ensembl		 PMID:20616062 GO_REF:0000107 NCBI chr 2:91,391,729...91,428,652
Ensembl chr 2:91,388,530...91,428,668 		JBrowse link
G Chmp5 charged multivesicular body protein 5 involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 5:56,081,385...56,098,529
Ensembl chr 5:56,081,343...56,098,529 		JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:4441223|PMID:20230755)		 UniProt
Ensembl
RGD		 PMID:20230755 GO_REF:0000024 GO_REF:0000107 MGI:4441223 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162 		JBrowse link
G Fbxw5 F-box and WD repeat domain containing 5 involved_in ISO
ISS		 (PMID:21725316)
GO_REF:0000024		 RGD
UniProt		 PMID:21725316 GO_REF:0000024 NCBI chr 3:8,322,543...8,327,092
Ensembl chr 3:8,322,543...8,327,092 		JBrowse link
G Gen1 GEN1 Holliday junction 5' flap endonuclease involved_in ISO (PMID:23108668), (PMID:23166748) RGD PMID:23108668 PMID:23166748 NCBI chr 6:33,947,599...33,978,461
Ensembl chr 6:33,948,206...33,978,401 		JBrowse link
G Nat10 N-acetyltransferase 10 involved_in ISO (PMID:31722219) RGD PMID:31722219 NCBI chr 3:90,111,643...90,149,891
Ensembl chr 3:90,111,645...90,149,927 		JBrowse link
G Npm1 nucleophosmin 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:3604807 (MGI:3604166|PMID:16007073)		 RGD PMID:16007073 PMID:21873635 MGI:3604166, RGD:13792537 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr 8:113,590,998...113,646,795
Ensembl chr 8:113,590,998...113,646,773 		JBrowse link
G Pkhd1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin involved_in ISO (PMID:20554582) RGD PMID:20554582 NCBI chr 9:22,547,396...23,037,443
Ensembl chr 9:22,549,513...23,037,381 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:31722219)		 UniProt
Ensembl
RGD		 PMID:31722219 GO_REF:0000024 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B involved_in ISO (PMID:20616062) RGD PMID:20616062 NCBI chr13:22,907,105...22,932,200
Ensembl chr13:22,907,109...22,932,229 		JBrowse link
G Xpo1 exportin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3610707|PMID:16297385)
GO_REF:0000107		 RGD
Ensembl		 PMID:16297385 GO_REF:0000107 MGI:3610707 NCBI chr14:97,233,282...97,275,536
Ensembl chr14:97,233,270...97,275,498 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 involved_in ISO (PMID:23108668) RGD PMID:23108668 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    cellular process 18233
      cell cycle process 1275
        centrosome cycle 145
          regulation of centrosome cycle 58
            negative regulation of centrosome cycle + 12
            positive regulation of centrosome cycle 0
            regulation of centrosome duplication + 52
Path 2
Term Annotations click to browse term
  biological_process 19553
    cellular process 18233
      cellular component organization or biogenesis 6802
        cellular component organization 6536
          organelle organization 3601
            cytoskeleton organization 1513
              microtubule cytoskeleton organization 658
                microtubule organizing center organization 160
                  centrosome cycle 145
                    regulation of centrosome cycle 58
                      negative regulation of centrosome cycle + 12
                      positive regulation of centrosome cycle 0
                      regulation of centrosome duplication + 52
paths to the root