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ONTOLOGY REPORT - ANNOTATIONS

Term:sphingoid biosynthetic process
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Accession:GO:0046520 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.
Synonyms:exact_synonym: sphingoid anabolism;   sphingoid biosynthesis;   sphingoid formation;   sphingoid synthesis


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sphingoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPTLC3 serine palmitoyltransferase long chain base subunit 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19648650) MGI
Ensembl		 PMID:19648650 GO_REF:0000107 NCBI chr20:12,966,584...13,125,802
Ensembl chr20:12,952,524...13,111,347 		JBrowse link
phytosphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACER3 alkaline ceramidase 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:71,911,204...72,077,528
Ensembl chr11:75,557,846...75,717,586 		JBrowse link
sphinganine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 acts_upstream_of_or_within ISO (PMID:19416652) MGI PMID:19416652 NCBI chr 9:63,087,798...63,174,977 JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9363775) Ensembl
MGI		 PMID:9363775 GO_REF:0000107 NCBI chr14:58,066,123...58,170,472
Ensembl chr14:77,266,545...77,370,663 		JBrowse link
sphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of_positive_effect
involved_in		 ISO
IEA		 (PMID:26510981) ARUK-UCL
Ensembl		 PMID:26510981 GO_REF:0000107 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776 		JBrowse link
G ACER1 alkaline ceramidase 1 involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr19:5,327,251...5,393,587
Ensembl chr19:6,252,300...6,281,016 		JBrowse link
G ACER2 alkaline ceramidase 2 involved_in IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr 9:19,216,891...19,262,477
Ensembl chr 9:19,709,402...19,750,896 		JBrowse link
G ACER3 alkaline ceramidase 3 involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr11:71,911,204...72,077,528
Ensembl chr11:75,557,846...75,717,586 		JBrowse link
G AGK acylglycerol kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:133,438,436...133,580,423
Ensembl chr 7:145,948,154...146,050,512 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 involved_in ISO (PMID:12815059)
(MGI:1267186|PMID:9653654)
(PMID:10610716)		 UniProt PMID:9653654 PMID:10610716 PMID:12815059 MGI:1267186 NCBI chr 8:17,272,632...17,300,902 JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,579,300...130,589,560
Ensembl chr 1:134,185,385...134,194,851 		JBrowse link
G LOC100985247 putative inactive neutral ceramidase B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:46,842,830...46,908,811
Ensembl chr10:48,969,434...49,025,336 		JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:70,331,370...70,336,043
Ensembl chr17:75,883,329...75,886,481 		JBrowse link
G SPHK2 sphingosine kinase 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:45,620,980...45,631,786
Ensembl chr19:54,213,166...54,224,767 		JBrowse link
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16216550) TreeGrafter
MGI		 PMID:16216550 GO_REF:0000118 NCBI chr 9:63,087,798...63,174,977 JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16216550) Ensembl
MGI
TreeGrafter		 PMID:16216550 GO_REF:0000107 GO_REF:0000118 NCBI chr14:58,066,123...58,170,472
Ensembl chr14:77,266,545...77,370,663 		JBrowse link
G SPTLC3 serine palmitoyltransferase long chain base subunit 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:12,966,584...13,125,802
Ensembl chr20:12,952,524...13,111,347 		JBrowse link
G SPTSSA serine palmitoyltransferase small subunit A involved_in ISO (PMID:19416851), (PMID:33558761) ComplexPortal PMID:19416851 PMID:33558761 NCBI chr14:15,190,833...15,219,882 JBrowse link
G SPTSSB serine palmitoyltransferase small subunit B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:158,358,718...158,385,625
Ensembl chr 3:166,406,488...166,406,718 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16313
    metabolic process 10179
      cellular metabolic process 8945
        cellular biosynthetic process 7125
          membrane lipid biosynthetic process 134
            sphingolipid biosynthetic process 96
              sphingoid biosynthetic process 15
                phytosphingosine biosynthetic process 1
                sphinganine biosynthetic process 2
                sphingosine biosynthetic process 15
Path 2
Term Annotations click to browse term
  biological_process 16313
    metabolic process 10179
      organic substance metabolic process 9739
        lipid metabolic process 1297
          cellular lipid metabolic process 981
            membrane lipid metabolic process 195
              membrane lipid biosynthetic process 134
                sphingolipid biosynthetic process 96
                  sphingoid biosynthetic process 15
                    phytosphingosine biosynthetic process 1
                    sphinganine biosynthetic process 2
                    sphingosine biosynthetic process 15
paths to the root