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ONTOLOGY REPORT - ANNOTATIONS


Term:sphingoid biosynthetic process
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Accession:GO:0046520 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.
Synonyms:exact_synonym: sphingoid anabolism;   sphingoid biosynthesis;   sphingoid formation;   sphingoid synthesis


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sphingoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 acts_upstream_of_or_within ISO (PMID:19648650) RGD PMID:19648650 NCBI chr 3:132,560,437...132,689,313
Ensembl chr 3:132,560,506...132,692,737
JBrowse link
phytosphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer3 alkaline ceramidase 3 involved_in IBA
ISO
PMID:21873635
(PMID:11356846), (PMID:20068046)
RGD PMID:11356846 PMID:20068046, PMID:21873635 RGD:13792537 NCBI chr 1:163,160,987...163,263,621
Ensembl chr 1:163,160,979...163,263,606
JBrowse link
sphinganine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 acts_upstream_of_or_within ISO MGI:3815115 (MGI:3846467|PMID:19416652) RGD PMID:19416652 MGI:3846467 NCBI chr17:11,856,525...11,895,566
Ensembl chr17:11,856,525...11,895,566
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 acts_upstream_of_or_within ISO (MGI:1098386|PMID:9363775) RGD PMID:9363775 MGI:1098386 NCBI chr 6:111,334,408...111,417,960
Ensembl chr 6:111,339,136...111,417,954
JBrowse link
sphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of_positive_effect
involved_in
ISO
IEA
(PMID:26510981)
GO_REF:0000107
RGD
Ensembl
PMID:26510981 GO_REF:0000107 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
JBrowse link
G Acer1 alkaline ceramidase 1 involved_in ISO (PMID:17713573), (PMID:20207939), (PMID:20628055)
(MGI:5800647|PMID:27126290), (MGI:6107252|PMID:29056331)
RGD PMID:17713573 PMID:20207939 PMID:20628055 PMID:27126290 PMID:29056331 MGI:5800647 MGI:6107252 NCBI chr 9:10,061,978...10,093,588
Ensembl chr 9:10,061,978...10,093,588
JBrowse link
G Acer2 alkaline ceramidase 2 involved_in ISO (PMID:16940153), (PMID:20089856), (PMID:20207939), (PMID:20628055)
(MGI:6116621|PMID:29401619)
RGD PMID:16940153 PMID:20089856 PMID:20207939 PMID:20628055 PMID:29401619 MGI:6116621 NCBI chr 5:105,230,540...105,279,732
Ensembl chr 5:105,230,580...105,279,731
JBrowse link
G Acer3 alkaline ceramidase 3 involved_in ISO (PMID:20068046), (PMID:20207939), (PMID:26792856)
(MGI:5749603|PMID:26474409)
RGD PMID:20068046 PMID:20207939 PMID:26474409 PMID:26792856 MGI:5749603 NCBI chr 1:163,160,987...163,263,621
Ensembl chr 1:163,160,979...163,263,606
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:1267186|PMID:9653654)
(PMID:10610716), (PMID:12815059)
UniProt
Ensembl
RGD
PMID:9653654 PMID:10610716 PMID:12815059 GO_REF:0000024 GO_REF:0000107 MGI:1267186 NCBI chr16:53,998,604...54,030,006
Ensembl chr16:53,998,560...54,040,836
JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in IDA
ISO
IBA
PMID:15123644
(MGI:3608219|PMID:16126722), (MGI:3640407|PMID:16380386), (MGI:6275120|PMID:10652340)
PMID:15217782
PMID:21873635
(PMID:30154232)
PMID:10488143
RGD PMID:10652340 PMID:16126722 PMID:16380386 PMID:30154232, PMID:15123644, PMID:15217782, PMID:21873635, PMID:10488143 MGI:3608219 MGI:3640407 MGI:6275120, RGD:13838793, RGD:13838794, RGD:13792537, RGD:13838800 NCBI chr 1:250,557,042...250,665,083
Ensembl chr 1:250,557,044...250,630,677
JBrowse link
G Gba glucosylceramidase beta involved_in ISO (PMID:19279011) RGD PMID:19279011 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601
JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO
IEA
IBA
UniProtKB:Q9NRA0 (PMID:23106337)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:23106337, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO
IBA
UniProtKB:Q9NYA1 (PMID:23106337)
PMID:21873635
RGD PMID:23106337, PMID:21873635 RGD:13792537 NCBI chr 1:101,692,972...101,700,604
Ensembl chr 1:101,692,973...101,697,277
JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3815115 (MGI:3814228|PMID:16216550)
RGD PMID:16216550, PMID:21873635 MGI:3814228, RGD:13792537 NCBI chr17:11,856,525...11,895,566
Ensembl chr17:11,856,525...11,895,566
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3815117 (MGI:3814228|PMID:16216550)
RGD PMID:16216550, PMID:21873635 MGI:3814228, RGD:13792537 NCBI chr 6:111,334,408...111,417,960
Ensembl chr 6:111,339,136...111,417,954
JBrowse link
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:132,560,437...132,689,313
Ensembl chr 3:132,560,506...132,692,737
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    metabolic process 11797
      nitrogen compound metabolic process 10017
        organonitrogen compound metabolic process 6803
          organonitrogen compound biosynthetic process 1999
            sphingolipid biosynthetic process 90
              sphingoid biosynthetic process 12
                phytosphingosine biosynthetic process 1
                sphinganine biosynthetic process 2
                sphingosine biosynthetic process 12
Path 2
Term Annotations click to browse term
  biological_process 19491
    metabolic process 11797
      primary metabolic process 10565
        lipid metabolic process 1362
          cellular lipid metabolic process 1018
            membrane lipid metabolic process 187
              membrane lipid biosynthetic process 127
                sphingolipid biosynthetic process 90
                  sphingoid biosynthetic process 12
                    phytosphingosine biosynthetic process 1
                    sphinganine biosynthetic process 2
                    sphingosine biosynthetic process 12
paths to the root