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ONTOLOGY REPORT - ANNOTATIONS

Term:sphingoid metabolic process
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Accession:GO:0046519 term browser browse the term
Definition:The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.
Synonyms:exact_synonym: sphingoid base metabolic process;   sphingoid base metabolism;   sphingoid metabolism


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3-keto-sphinganine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdsr 3-ketodihydrosphingosine reductase involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:15364918)		 RGD PMID:15364918 PMID:21873635 RGD:13792537 NCBI chr13:22,862,117...22,894,118
Ensembl chr13:22,862,117...22,894,108 		JBrowse link
phytosphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer3 alkaline ceramidase 3 involved_in IBA
ISO		 PMID:21873635
(PMID:11356846), (PMID:20068046)		 RGD PMID:11356846 PMID:20068046 PMID:21873635 RGD:13792537 NCBI chr 1:152,504,180...152,606,596
Ensembl chr 1:152,504,186...152,606,591 		JBrowse link
sphinganine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 acts_upstream_of_or_within ISO MGI:3815115 (MGI:3846467|PMID:19416652) RGD PMID:19416652 MGI:3846467 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1098386|PMID:9363775)
GO_REF:0000107		 RGD
Ensembl		 PMID:9363775 GO_REF:0000107 MGI:1098386 NCBI chr 6:106,948,681...107,031,584
Ensembl chr 6:106,950,949...107,031,542 		JBrowse link
sphinganine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Degs2 delta(4)-desaturase, sphingolipid 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
SGD:S000002705 (MGI:3505861|PMID:11937514)
(MGI:3694278|PMID:16571104)		 RGD PMID:11937514 PMID:16571104 PMID:21873635 MGI:3505861 MGI:3694278, RGD:13792537 NCBI chr 6:127,596,063...127,613,293
Ensembl chr 6:127,596,071...127,613,293 		JBrowse link
sphingoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 acts_upstream_of_or_within ISO (PMID:19648650) RGD PMID:19648650 NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010 		JBrowse link
sphingosine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of_positive_effect
involved_in		 ISO
IEA		 (PMID:26510981)
GO_REF:0000107		 RGD
Ensembl		 PMID:26510981 GO_REF:0000107 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Acer1 alkaline ceramidase 1 involved_in ISO
IBA		 (PMID:17713573), (PMID:20207939), (PMID:20628055)
PMID:21873635
(MGI:5800647|PMID:27126290), (MGI:6107252|PMID:29056331)		 RGD PMID:17713573 PMID:20207939 PMID:20628055 PMID:27126290 PMID:29056331 More... MGI:5800647 MGI:6107252, RGD:13792537 NCBI chr 9:1,792,790...1,824,434
Ensembl chr 9:1,793,139...1,824,434 		JBrowse link
G Acer2 alkaline ceramidase 2 involved_in ISO
IBA		 (PMID:16940153), (PMID:20089856), (PMID:20207939), (PMID:20628055)
(MGI:6116621|PMID:29401619)
PMID:21873635		 RGD PMID:16940153 PMID:20089856 PMID:20207939 PMID:20628055 PMID:29401619 More... MGI:6116621, RGD:13792537 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Acer3 alkaline ceramidase 3 involved_in ISO (PMID:20068046), (PMID:20207939), (PMID:26792856)
(MGI:5749603|PMID:26474409)		 RGD PMID:20068046 PMID:20207939 PMID:26474409 PMID:26792856 MGI:5749603 NCBI chr 1:152,504,180...152,606,596
Ensembl chr 1:152,504,186...152,606,591 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:10610716), (PMID:12815059)
(MGI:1267186|PMID:9653654)		 UniProt
Ensembl
RGD		 PMID:9653654 PMID:10610716 PMID:12815059 GO_REF:0000024 GO_REF:0000107 MGI:1267186 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in IDA
ISO
IBA		 PMID:10488143
(PMID:30154232)
PMID:21873635
PMID:15217782
(MGI:3608219|PMID:16126722), (MGI:3640407|PMID:16380386), (MGI:6275120|PMID:10652340)
PMID:15123644		 RGD PMID:10652340 PMID:16126722 PMID:16380386 PMID:30154232 PMID:10488143 More... MGI:3608219 MGI:3640407 MGI:6275120, RGD:13838800, RGD:13792537, RGD:13838794, RGD:13838793 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162 		JBrowse link
G ENSRNOG00000069695 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr14:25,729,638...25,730,194 JBrowse link
G Gba glucosylceramidase beta involved_in ISO (PMID:19279011) RGD PMID:19279011 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO
IBA
IEA		 UniProtKB:Q9NRA0 (PMID:23106337)
PMID:21873635
GO_REF:0000107		 RGD
Ensembl		 PMID:23106337 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO
IBA		 UniProtKB:Q9NYA1 (PMID:23106337)
PMID:21873635		 RGD PMID:23106337 PMID:21873635 RGD:13792537 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3815115 (MGI:3814228|PMID:16216550)
(PMID:19416851), (PMID:33558761)
PMID:21873635		 RGD PMID:16216550 PMID:19416851 PMID:33558761 PMID:21873635 MGI:3814228, RGD:13792537 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 MGI:3815117 (MGI:3814228|PMID:16216550)
(PMID:19416851), (PMID:33558761)
GO_REF:0000107
PMID:21873635		 RGD
Ensembl		 PMID:16216550 PMID:19416851 PMID:33558761 PMID:21873635 GO_REF:0000107 MGI:3814228, RGD:13792537 NCBI chr 6:106,948,681...107,031,584
Ensembl chr 6:106,950,949...107,031,542 		JBrowse link
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 involved_in ISO
IBA		 (PMID:19416851)
PMID:21873635		 RGD PMID:19416851 PMID:21873635 RGD:13792537 NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010 		JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A involved_in ISO (PMID:19416851), (PMID:33558761) RGD PMID:19416851 PMID:33558761 NCBI chr 6:72,144,714...72,156,130
Ensembl chr 6:72,144,714...72,156,214 		JBrowse link
G Sptssb serine palmitoyltransferase, small subunit B involved_in ISO (PMID:19416851) RGD PMID:19416851 NCBI chr 2:154,133,728...154,162,127
Ensembl chr 2:154,133,733...154,163,120 		JBrowse link
sphingosine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO
ISS		 (PMID:10781606), (PMID:15946935), (PMID:16229686), (PMID:17475390), (PMID:26190575)
GO_REF:0000024		 RGD
UniProt		 PMID:10781606 PMID:15946935 PMID:16229686 PMID:17475390 PMID:26190575 GO_REF:0000024 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162 		JBrowse link
G Naaa N-acylethanolamine acid amidase involved_in ISO
ISS		 (PMID:15655246)
GO_REF:0000024		 RGD
UniProt		 PMID:15655246 GO_REF:0000024 NCBI chr14:15,777,306...15,796,411
Ensembl chr14:15,777,306...15,796,410 		JBrowse link
G Plpp1 phospholipid phosphatase 1 involved_in IDA
ISO		 PMID:10359651
(MGI:6383560|PMID:10359651)
PMID:8663293
(PMID:9705349)		 RGD PMID:9705349 PMID:10359651 PMID:10359651 PMID:8663293 MGI:6383560, RGD:15090857, RGD:15090855 NCBI chr 2:44,439,002...44,500,430
Ensembl chr 2:44,438,994...44,501,268 		JBrowse link
G Plpp2 phospholipid phosphatase 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:9705349)		 UniProt
RGD		 PMID:9705349 GO_REF:0000024 NCBI chr 7:10,175,918...10,184,032
Ensembl chr 7:10,175,948...10,184,071 		JBrowse link
G Plpp3 phospholipid phosphatase 3 involved_in ISO
IEA
ISS		 (PMID:9305923), (PMID:9705349)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:9305923 PMID:9705349 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205 		JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(MGI:2176350|PMID:11756451)		 Ensembl
RGD		 PMID:11756451 PMID:21873635 GO_REF:0000107 MGI:2176350, RGD:13792537 NCBI chr 6:94,425,339...94,446,534
Ensembl chr 6:94,425,339...94,446,534 		JBrowse link
G Sgpp2 sphingosine-1-phosphate phosphatase 2 involved_in ISO
IBA		 (PMID:12411432)
PMID:21873635		 RGD PMID:12411432 PMID:21873635 RGD:13792537 NCBI chr 9:79,762,658...79,884,665
Ensembl chr 9:79,763,284...79,880,457 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO
ISS		 (PMID:20577214)
GO_REF:0000024		 RGD
UniProt		 PMID:20577214 GO_REF:0000024 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in
acts_upstream_of_or_within		 ISO (MGI:3703830|PMID:17346996)
MGI:3580701 (MGI:3608224|PMID:16093248)		 RGD PMID:16093248 PMID:17346996 MGI:3608224 MGI:3703830 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19898
    metabolic process 12211
      nitrogen compound metabolic process 10349
        organonitrogen compound metabolic process 7049
          sphingolipid metabolic process 152
            sphingoid metabolic process 23
              3-keto-sphinganine metabolic process 1
              phytosphingosine metabolic process + 1
              sphinganine metabolic process + 3
              sphingoid biosynthetic process + 15
              sphingoid catabolic process + 0
              sphingosine metabolic process + 21
Path 2
Term Annotations click to browse term
  biological_process 19898
    metabolic process 12211
      primary metabolic process 10967
        lipid metabolic process 1456
          cellular lipid metabolic process 1054
            membrane lipid metabolic process 201
              sphingolipid metabolic process 152
                sphingoid metabolic process 23
                  3-keto-sphinganine metabolic process 1
                  phytosphingosine metabolic process + 1
                  sphinganine metabolic process + 3
                  sphingoid biosynthetic process + 15
                  sphingoid catabolic process + 0
                  sphingosine metabolic process + 21
paths to the root