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ONTOLOGY REPORT - ANNOTATIONS

Term:ceramide catabolic process
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Accession:GO:0046514 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid.
Synonyms:exact_synonym: ceramide breakdown;   ceramide catabolism;   ceramide degradation


show annotations for term's descendants           Sort by:
ceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer1 alkaline ceramidase 1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:20207939)
(PMID:12783875)
GO_REF:0000033
(MGI:5800647|PMID:27126290)		 RGD
GO_Central		 PMID:12783875 PMID:20207939 PMID:27126290 GO_REF:0000033 MGI:5800647 NCBI chr 9:1,794,340...1,824,432
Ensembl chr 9:1,793,139...1,824,434 		JBrowse link
G Acer2 alkaline ceramidase 2 involved_in ISO
IBA		 (PMID:16940153), (PMID:20207939)
GO_REF:0000033		 RGD
GO_Central		 PMID:16940153 PMID:20207939 GO_REF:0000033 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Acer3 alkaline ceramidase 3 involved_in ISO (PMID:20207939), (PMID:26792856), (PMID:30575723)
(MGI:5749603|PMID:26474409)		 RGD PMID:20207939 PMID:26474409 PMID:26792856 PMID:30575723 MGI:5749603 NCBI chr 1:152,504,180...152,606,596
Ensembl chr 1:152,504,186...152,606,591 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:1267186|PMID:9653654), (MGI:5505361|PMID:23770692)
(PMID:10610716), (PMID:12815059)		 UniProt
Ensembl
RGD		 PMID:9653654 PMID:10610716 PMID:12815059 PMID:23770692 GO_REF:0000024 GO_REF:0000107 MGI:1267186 MGI:5505361 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in IDA
IBA
IEA
ISO		 PMID:10488143
GO_REF:0000033
GO_REF:0000002
PMID:15123644
(MGI:3608219|PMID:16126722), (MGI:3640407|PMID:16380386), (MGI:6275120|PMID:10652340)
PMID:15217782
(PMID:10781606), (PMID:15946935), (PMID:16229686), (PMID:17475390), (PMID:19345744), (PMID:30154232)		 GO_Central
InterPro
RGD		 PMID:10652340 PMID:10781606 PMID:15946935 PMID:16126722 PMID:16229686 More... GO_REF:0000002 GO_REF:0000033 MGI:3608219 MGI:3640407 MGI:6275120, RGD:13838800, RGD:13838793, RGD:13838794 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162 		JBrowse link
G Cel carboxyl ester lipase involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
MGI:2180867 (PMID:11733511)		 Ensembl
GO_Central
RGD		 PMID:11733511 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035 		JBrowse link
galactosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Galc galactosylceramidase involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:8399327)
MGI:1856218 (PMID:11371512)
GO_REF:0000033
(MGI:78941|PMID:8769874)		 RGD
GO_Central		 PMID:8399327 PMID:8769874 PMID:11371512 GO_REF:0000033 MGI:78941 NCBI chr 6:117,452,888...117,522,281
Ensembl chr 6:117,452,895...117,515,830 		JBrowse link
G Gba3 glucosylceramidase beta 3 involved_in ISO (PMID:17595169) RGD PMID:17595169 NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO MGI:2183897 (PMID:11371512) RGD PMID:11371512 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498 		JBrowse link
ganglioside catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gm2a ganglioside GM2 activator involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1861930 (PMID:9223328)		 GO_Central
RGD		 PMID:9223328 GO_REF:0000033 NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757 		JBrowse link
G Hexa hexosaminidase subunit alpha involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA		 GO_REF:0000024
MGI:1857181|MGI:2429698 (PMID:7937929), (PMID:8789434), (PMID:9223328), (PMID:9645704)
GO_REF:0000033
(PMID:8123671), (PMID:8672428), (PMID:9694901)		 UniProt
RGD
GO_Central		 PMID:7937929 PMID:8123671 PMID:8672428 PMID:8789434 PMID:9223328 More... GO_REF:0000024 GO_REF:0000033 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013 		JBrowse link
G Hexb hexosaminidase subunit beta involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA
IEA		 GO_REF:0000024
MGI:1857438|MGI:2429701 (PMID:10021458), (PMID:12657883), (PMID:12756243), (PMID:15748167), (PMID:8566348), (PMID:8789434), (PMID:9223328), (PMID:9645704)
GO_REF:0000033
(PMID:8123671), (PMID:8672428)
GO_REF:0000107		 UniProt
RGD
GO_Central
Ensembl		 PMID:8123671 PMID:8566348 PMID:8672428 PMID:8789434 PMID:9223328 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223 		JBrowse link
G Neu1 neuraminidase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,897,480...3,901,745
Ensembl chr20:3,897,480...3,901,745 		JBrowse link
G Neu2 neuraminidase 2 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(MGI:1354405|PMID:10713120)
(PMID:14613940), (PMID:22228546)		 UniProt
GO_Central
Ensembl
RGD		 PMID:10713120 PMID:14613940 PMID:22228546 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:1354405 NCBI chr 9:88,218,494...88,267,356
Ensembl chr 9:88,249,135...88,267,355 		JBrowse link
G Neu3 neuraminidase 3 involved_in ISO
IBA
ISS		 (PMID:10861246), (PMID:11298736), (PMID:15847605), (PMID:17334392)
GO_REF:0000033
(MGI:3040535|PMID:14970224), (MGI:3765376|PMID:17708748), (MGI:6478528|PMID:11696012)
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:10861246 PMID:11298736 PMID:11696012 PMID:14970224 PMID:15847605 More... GO_REF:0000024 GO_REF:0000033 MGI:3040535 MGI:3765376 MGI:6478528 NCBI chr 1:154,137,732...154,148,879
Ensembl chr 1:154,050,855...154,148,813 		JBrowse link
G Neu4 neuraminidase 4 involved_in ISO
IBA		 (PMID:15213228), (PMID:15847605)
GO_REF:0000033
(MGI:4361102|PMID:19506080)		 RGD
GO_Central		 PMID:15213228 PMID:15847605 PMID:19506080 GO_REF:0000033 MGI:4361102 NCBI chr 9:94,396,920...94,402,576
Ensembl chr 9:94,396,920...94,402,576 		JBrowse link
glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba1 glucosylceramidase beta 1 involved_in ISO
IBA		 (MGI:5141165|PMID:21700325), (MGI:5501380|PMID:23707074), (MGI:6271235|PMID:24211208)
GO_REF:0000033
(PMID:16293621), (PMID:19279011), (PMID:21700325), (PMID:24022302), (PMID:24211208), (PMID:25584808), (PMID:9201993)		 RGD
GO_Central		 PMID:9201993 PMID:16293621 PMID:19279011 PMID:21700325 PMID:23707074 More... GO_REF:0000033 MGI:5141165 MGI:5501380 MGI:6271235 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Gba2 glucosylceramidase beta 2 involved_in ISO
IEA
ISS		 (PMID:17080196), (PMID:30308956)
GO_REF:0000107
(MGI:3690511|PMID:17080196), (MGI:5484792|PMID:23250757)
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17080196 PMID:23250757 PMID:30308956 GO_REF:0000024 GO_REF:0000107 MGI:3690511 MGI:5484792 NCBI chr 5:57,822,389...57,834,522
Ensembl chr 5:57,822,389...57,834,072 		JBrowse link
G Gba3 glucosylceramidase beta 3 involved_in
NOT|involved_in		 ISO (PMID:17595169), (PMID:26724485)
(PMID:20728381)		 RGD PMID:17595169 PMID:20728381 PMID:26724485 NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653 		JBrowse link
glycosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba3 glucosylceramidase beta 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653 		JBrowse link
G Gla galactosidase, alpha acts_upstream_of_or_within ISO MGI:1861794 (PMID:10840053), (PMID:10841515), (PMID:11752062), (PMID:15629890), (PMID:9122231) RGD PMID:9122231 PMID:10840053 PMID:10841515 PMID:11752062 PMID:15629890 NCBI chr  X:97,769,227...97,780,646
Ensembl chr  X:97,768,996...97,780,664 		JBrowse link
G Lct lactase involved_in IDA PMID:4752949 UniProt PMID:4752949 RGD:151356630 NCBI chr13:39,781,929...39,824,456
Ensembl chr13:39,781,929...39,824,456 		JBrowse link
positive regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcd protein kinase C, delta involved_in ISO
IEA		 (PMID:19279011)
GO_REF:0000107		 RGD
Ensembl		 PMID:19279011 GO_REF:0000107 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir127 microRNA 127 acts_upstream_of ISO UniProtKB:P04062 (PMID:25584808) RGD PMID:25584808 NCBI chr 6:128,546,215...128,546,311
Ensembl chr 6:128,546,215...128,546,311 		JBrowse link
G Mir16 microRNA 16 acts_upstream_of_or_within ISO UniProtKB:P04062 (PMID:25584808) RGD PMID:25584808 NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443 		JBrowse link
G Mir195 microRNA 195 acts_upstream_of_or_within ISO UniProtKB:P04062 (PMID:25584808) RGD PMID:25584808 NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    metabolic process 12289
      amide metabolic process 439
        ceramide metabolic process 111
          ceramide catabolic process 24
            ganglioside catabolic process 7
            glycosylceramide catabolic process + 11
Path 2
Term Annotations click to browse term
  biological_process 20115
    metabolic process 12289
      primary metabolic process 10923
        lipid metabolic process 1460
          cellular lipid metabolic process 1068
            membrane lipid metabolic process 209
              sphingolipid metabolic process 157
                ceramide metabolic process 111
                  ceramide catabolic process 24
                    ganglioside catabolic process 7
                    glycosylceramide catabolic process + 11
paths to the root