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ONTOLOGY REPORT - ANNOTATIONS

Term:ceramide biosynthetic process
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Accession:GO:0046513 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.
Synonyms:exact_synonym: ceramide anabolism;   ceramide biosynthesis;   ceramide formation;   ceramide synthesis


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ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGK acylglycerol kinase involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:21873635)
(MGI:3054595|PMID:15252046)		 GO_Central
Ensembl
GO_Central
MGI		 PMID:15252046 PMID:21873635 GO_REF:0000107 MGI:3054595 NCBI chr18:8,263,761...8,369,060
Ensembl chr18:8,263,896...8,368,972 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr12:53,292,530...53,302,850
Ensembl chr12:53,292,526...53,302,993 		JBrowse link
G ALOXE3 arachidonate lipoxygenase 3 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr12:53,309,845...53,331,780
Ensembl chr12:53,309,848...53,331,523 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr17:5,712,048...5,749,811
Ensembl chr17:5,712,058...5,758,821 		JBrowse link
G ASAH2 N-acylsphingosine amidohydrolase 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr14:99,018,111...99,141,374
Ensembl chr14:99,025,005...99,129,100 		JBrowse link
G CERS2 ceramide synthase 2 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (MGI:3696894|PMID:15823095)
(PMID:21873635)		 MGI
GO_Central
UniProt
InterPro
Ensembl
UniProt
GO_Central		 PMID:15823095 PMID:21873635 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 MGI:3696894 NCBI chr 4:98,250,773...98,260,504
Ensembl chr 4:98,250,964...98,260,427 		JBrowse link
G CERS3 ceramide synthase 3 involved_in IBA
IEA		 (PMID:21873635) GO_Central
GO_Central
Ensembl
UniProt
InterPro		 PMID:21873635 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:139,027,604...139,154,830
Ensembl chr 1:139,030,642...139,136,874 		JBrowse link
G CERS4 ceramide synthase 4 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (MGI:2679796|PMID:12912983), (MGI:3696894|PMID:15823095)
(PMID:21873635)		 MGI
GO_Central
UniProt
Ensembl
InterPro
UniProt
GO_Central		 PMID:12912983 PMID:15823095 PMID:21873635 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 MGI:2679796 MGI:3696894 NCBI chr 2:71,004,418...71,047,968
Ensembl chr 2:71,004,420...71,048,248 		JBrowse link
G CERS5 ceramide synthase 5 involved_in IBA
IEA		 (PMID:21873635) GO_Central
GO_Central
UniProt
Ensembl
InterPro
UniProt		 PMID:21873635 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chr 5:16,038,918...16,070,103
Ensembl chr 5:16,037,747...16,070,007 		JBrowse link
G CERS6 ceramide synthase 6 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (MGI:3696894|PMID:15823095)
(PMID:21873635)		 MGI
GO_Central
UniProt
Ensembl
InterPro
UniProt
GO_Central		 PMID:15823095 PMID:21873635 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 MGI:3696894 NCBI chr15:74,927,088...75,261,558
Ensembl chr15:74,927,130...75,261,554 		JBrowse link
G COPE COPI coat complex subunit epsilon involved_in IBA
IEA		 (PMID:21873635) GO_Central
UniProt
InterPro		 PMID:21873635 GO_REF:0000002 GO_REF:0000117 NCBI chr 2:58,930,929...58,948,466
Ensembl chr 2:58,930,931...58,948,469 		JBrowse link
G CYP4F22 cytochrome P450 family 4 subfamily F member 22 involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl
GO_Central		 PMID:21873635 GO_REF:0000107 NCBI chr 2:62,078,403...62,110,891
Ensembl chr 2:62,081,269...62,110,899 		JBrowse link
G DEGS1 delta 4-desaturase, sphingolipid 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:21873635)
(MGI:5466789|PMID:22984457)		 GO_Central
GO_Central
MGI		 PMID:21873635 PMID:22984457 MGI:5466789 NCBI chr10:12,529,021...12,568,447
Ensembl chr10:12,557,767...12,568,978 		JBrowse link
G DEGS2 delta 4-desaturase, sphingolipid 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:21873635)
(MGI:3694278|PMID:16571104)		 GO_Central
MGI		 PMID:16571104 PMID:21873635 MGI:3694278 NCBI chr 7:121,058,102...121,131,612
Ensembl chr 7:121,058,105...121,076,328 		JBrowse link
G ELOVL1 ELOVL fatty acid elongase 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 6:167,881,357...167,886,125
Ensembl chr 6:167,881,352...167,886,124 		JBrowse link
G FA2H fatty acid 2-hydroxylase involved_in ISO (PMID:15337768)
(MGI:6245295|PMID:22517924)		 UniProt PMID:15337768 PMID:22517924 MGI:6245295 NCBI chr 6:12,855,330...12,910,821
Ensembl chr 6:12,855,421...12,910,818 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 4:94,583,905...94,606,689
Ensembl chr 4:94,584,134...94,609,745 		JBrowse link
G GDF1 growth differentiation factor 1 involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000117 NCBI chr 2:58,951,463...58,972,692
Ensembl chr 2:58,951,727...58,974,670 		JBrowse link
G P2RX1 purinergic receptor P2X 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3640029|PMID:16325464) Ensembl
Ensembl
MGI		 PMID:16325464 GO_REF:0000107 MGI:3640029 NCBI chr12:49,956,329...49,974,789
Ensembl chr12:49,956,327...49,974,671 		JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3640029|PMID:16325464) Ensembl
Ensembl
MGI		 PMID:16325464 GO_REF:0000107 MGI:3640029 NCBI chr14:31,415,188...31,476,502
Ensembl chr14:31,415,193...31,476,472 		JBrowse link
G PNPLA1 patatin like phospholipase domain containing 1 involved_in ISO (MGI:5882269|PMID:27751867)
(PMID:27751867)		 UniProt PMID:27751867 MGI:5882269 NCBI chr 7:31,987,596...32,025,673
Ensembl chr 7:31,988,197...32,025,245 		JBrowse link
G SAMD8 sterile alpha motif domain containing 8 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:21873635)
(MGI:5707904|PMID:25667419)
(MGI:5632043|PMID:25605874), (MGI:5707904|PMID:25667419)		 GO_Central
Ensembl
GO_Central
MGI		 PMID:21873635 PMID:25605874 PMID:25667419 GO_REF:0000107 MGI:5632043 MGI:5707904 NCBI chr14:77,679,287...77,737,657
Ensembl chr14:77,636,149...77,737,654 		JBrowse link
G SGMS1 sphingomyelin synthase 1 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:21873635)
(PMID:25605874)
(MGI:5632043|PMID:25605874)		 Ensembl
GO_Central
Ensembl
MGI
GO_Central		 PMID:21873635 PMID:25605874 GO_REF:0000107 MGI:5632043 NCBI chr14:99,147,266...99,458,111
Ensembl chr14:99,147,272...99,185,082 		JBrowse link
G SGMS2 sphingomyelin synthase 2 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:21873635)
(MGI:5632043|PMID:25605874)		 GO_Central
GO_Central
Ensembl
MGI		 PMID:21873635 PMID:25605874 GO_REF:0000107 MGI:5632043 NCBI chr 8:114,052,726...114,145,946
Ensembl chr 8:114,057,603...114,076,154 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in IBA
IEA
ISO		 (PMID:21873635) GO_Central
UniProt
GO_Central
RGD		 PMID:17261082 PMID:21873635 GO_REF:0000117 RGD:1601344 NCBI chr 9:3,324,091...3,328,493
Ensembl chr 9:3,324,442...3,328,457 		JBrowse link
G SMPD2 sphingomyelin phosphodiesterase 2 involved_in IBA
ISO		 (PMID:21873635) GO_Central
GO_Central
RGD		 PMID:12473648 PMID:21873635 RGD:1581395 NCBI chr 1:75,508,303...75,511,572
Ensembl chr 1:75,508,350...75,512,153 		JBrowse link
G SMPD4 sphingomyelin phosphodiesterase 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:50,663,488...50,689,355
Ensembl chr14:50,663,608...50,689,352 		JBrowse link
G SMPD5 sphingomyelin phosphodiesterase 5 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 4:639,228...643,057 JBrowse link
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:21873635)
(PMID:25691431)
(MGI:3814228|PMID:16216550)		 GO_Central
GO_Central
Ensembl
MGI		 PMID:16216550 PMID:21873635 PMID:25691431 GO_REF:0000107 MGI:3814228 NCBI chr14:3,081,964...3,138,113
Ensembl chr14:3,081,972...3,138,103 		JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:21873635)
(PMID:25691431)
(MGI:3814228|PMID:16216550)		 GO_Central
GO_Central
Ensembl
MGI		 PMID:16216550 PMID:21873635 PMID:25691431 GO_REF:0000107 MGI:3814228 NCBI chr 7:100,545,360...100,638,973
Ensembl chr 7:100,544,478...100,638,905 		JBrowse link
G SPTLC3 serine palmitoyltransferase long chain base subunit 3 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr17:21,769,388...21,903,269
Ensembl chr17:21,769,484...21,903,264 		JBrowse link
G SPTSSA serine palmitoyltransferase small subunit A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr 7:65,302,887...65,325,877
Ensembl chr 7:65,302,858...65,326,728 		JBrowse link
G SPTSSB serine palmitoyltransferase small subunit B involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:21873635)
(MGI:5689923|PMID:26438849)		 Ensembl
GO_Central
Ensembl
MGI
GO_Central		 PMID:21873635 PMID:26438849 GO_REF:0000107 MGI:5689923 NCBI chr13:101,023,238...101,059,917
Ensembl chr13:101,023,812...101,059,885 		JBrowse link
G TLCD3B TLC domain containing 3B involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:21873635)
(MGI:5490837|PMID:23275342)		 GO_Central
Ensembl
GO_Central
MGI		 PMID:21873635 PMID:23275342 GO_REF:0000107 MGI:5490837 NCBI chr 3:18,224,652...18,231,416
Ensembl chr 3:18,223,875...18,231,844 		JBrowse link
galactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3GALT1 beta-1,3-galactosyltransferase 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr15:73,772,833...74,340,060
Ensembl chr15:74,335,112...74,339,380 		JBrowse link
G B3GALT2 beta-1,3-galactosyltransferase 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr10:613,464...623,587
Ensembl chr10:613,608...624,131 		JBrowse link
G B4GALT3 beta-1,4-galactosyltransferase 3 involved_in IBA
IEA		 (PMID:21873635) GO_Central
GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr 4:89,278,256...89,284,407
Ensembl chr 4:89,278,439...89,284,400 		JBrowse link
G FA2H fatty acid 2-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:12,855,330...12,910,821
Ensembl chr 6:12,855,421...12,910,818 		JBrowse link
G GAL3ST1 galactose-3-O-sulfotransferase 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:21873635)
(MGI:1355015|PMID:10727929)		 GO_Central
GO_Central
Ensembl
MGI
Ensembl		 PMID:10727929 PMID:21873635 GO_REF:0000107 MGI:1355015 NCBI chr14:47,455,089...47,476,459
Ensembl chr14:47,457,787...47,476,455 		JBrowse link
G UGT8 UDP glycosyltransferase 8 involved_in ISO PMID:8713090 UniProt PMID:8713090 RGD:39458006 NCBI chr 8:108,233,134...108,315,284
Ensembl chr 8:108,233,143...108,314,921 		JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3GALT4 beta-1,3-galactosyltransferase 4 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 7:29,643,049...29,644,847
Ensembl chr 7:29,643,182...29,648,604 		JBrowse link
G B4GALNT1 beta-1,4-N-acetyl-galactosaminyltransferase 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:21873635)
(MGI:1331265|PMID:10021458)		 GO_Central
GO_Central
Ensembl
MGI		 PMID:10021458 PMID:21873635 GO_REF:0000107 MGI:1331265 NCBI chr 5:22,889,654...22,897,386
Ensembl chr 5:22,889,656...22,897,508 		JBrowse link
G ST6GALNAC3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr 6:136,633,410...137,201,213
Ensembl chr 6:136,633,441...137,201,252 		JBrowse link
G ST6GALNAC4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr 1:268,391,851...268,402,449
Ensembl chr 1:268,391,855...268,402,407 		JBrowse link
G ST6GALNAC5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:136,207,838...136,391,083
Ensembl chr 6:136,204,374...136,390,995 		JBrowse link
G ST6GALNAC6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 acts_upstream_of_or_within ISO (MGI:1354410|PMID:10702226) MGI PMID:10702226 MGI:1354410 NCBI chr 1:268,371,569...268,383,559 JBrowse link
G ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 7:86,450,302...86,514,232
Ensembl chr 7:86,446,149...86,514,393 		JBrowse link
G ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:106,683,536...106,701,165
Ensembl chr 1:106,683,562...106,696,300 		JBrowse link
G ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 2:106,754,831...106,845,806
Ensembl chr 2:106,754,701...106,845,830 		JBrowse link
G ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr10:43,601,677...43,755,154
Ensembl chr10:43,602,908...43,755,277 		JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4GALT5 beta-1,4-galactosyltransferase 5 involved_in IEA
ISS		 Ensembl
UniProt
Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:51,257,273...51,334,566
Ensembl chr17:51,259,813...51,334,020 		JBrowse link
G B4GALT6 beta-1,4-galactosyltransferase 6 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 6:115,525,515...115,593,265
Ensembl chr 6:115,524,636...115,593,270 		JBrowse link
G ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in IEA
IBA		 (PMID:21873635) Ensembl
GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr 4:7,814,492...7,911,053
Ensembl chr 4:7,896,554...7,909,505 		JBrowse link
G ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in IEA
IBA		 (PMID:21873635) Ensembl
GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr 6:13,402,336...13,456,495
Ensembl chr 6:13,402,345...13,419,378 		JBrowse link
G ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 6:167,363,348...167,596,892
Ensembl chr 6:167,363,347...167,595,835 		JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FA2H fatty acid 2-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:12,855,330...12,910,821
Ensembl chr 6:12,855,421...12,910,818 		JBrowse link
G UGCG UDP-glucose ceramide glucosyltransferase involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl
GO_Central		 PMID:21873635 GO_REF:0000107 NCBI chr 1:252,651,850...252,690,817
Ensembl chr 1:252,651,879...252,688,550 		JBrowse link
lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4GALT4 beta-1,4-galactosyltransferase 4 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr13:140,969,561...141,003,936
Ensembl chr13:140,969,602...141,003,929 		JBrowse link
G B4GALT6 beta-1,4-galactosyltransferase 6 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 6:115,525,515...115,593,265
Ensembl chr 6:115,524,636...115,593,270 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:21873635)
(PMID:25691431)		 GO_Central
Ensembl
MGI		 PMID:21873635 PMID:25691431 GO_REF:0000107 NCBI chr15:94,359,784...94,377,331
Ensembl chr15:94,359,358...94,377,303 		JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:21873635)
(PMID:25691431)		 GO_Central
Ensembl
MGI		 PMID:21873635 PMID:25691431 GO_REF:0000107 NCBI chr 5:21,262,134...21,264,689
Ensembl chr 5:21,262,193...21,264,685 		JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:25691431)
(MGI:5638294|PMID:25691431)
(PMID:21873635)		 Ensembl
Ensembl
MGI
GO_Central		 PMID:21873635 PMID:25691431 GO_REF:0000107 MGI:5638294 NCBI chr12:22,411,130...22,417,744
Ensembl chr12:22,411,587...22,417,736 		JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr12:5,114,946...5,122,580
Ensembl chr12:5,114,947...5,120,083 		JBrowse link
omega-hydroxyceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PNPLA1 patatin like phospholipase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:31,987,596...32,025,673
Ensembl chr 7:31,988,197...32,025,245 		JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCN1 cellular communication network factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3849354|PMID:19364818) Ensembl
Ensembl
MGI		 PMID:19364818 GO_REF:0000107 MGI:3849354 NCBI chr 4:130,392,404...130,395,179
Ensembl chr 4:130,392,407...130,395,150 		JBrowse link
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (MGI:4947032|PMID:21177474) UniProt PMID:21177474 MGI:4947032 NCBI chr12:2,612,543...2,619,541
Ensembl chr12:2,612,574...2,619,519 		JBrowse link
G PLA2G6 phospholipase A2 group VI involved_in ISO
IBA		 (PMID:21873635) RGD
GO_Central		 PMID:18936091 PMID:21873635 RGD:6482750 NCBI chr 5:9,713,809...9,777,921
Ensembl chr 5:9,713,873...9,777,918 		JBrowse link
G PRKCD protein kinase C delta involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,610...35,323,356 		JBrowse link
G SIRT3 sirtuin 3 involved_in ISO (MGI:5755322|PMID:26620563) UniProt PMID:26620563 MGI:5755322 NCBI chr 2:38,465...55,074
Ensembl chr 2:38,464...55,101 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 ISO RGD PMID:20096352 RGD:10041064 NCBI chr 6:28,938,287...29,025,397
Ensembl chr 6:28,938,290...29,025,357 		JBrowse link
G SPHK2 sphingosine kinase 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 6:53,982,911...53,986,779
Ensembl chr 6:53,979,012...53,986,768 		JBrowse link
regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:6393026|PMID:31880535) MGI
Ensembl
UniProt		 PMID:31880535 GO_REF:0000107 GO_REF:0000117 MGI:6393026 NCBI chr15:94,359,784...94,377,331
Ensembl chr15:94,359,358...94,377,303 		JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IEA UniProt GO_REF:0000117 NCBI chr 5:21,262,134...21,264,689
Ensembl chr 5:21,262,193...21,264,685 		JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:6393026|PMID:31880535) MGI
UniProt
Ensembl
UniProt		 PMID:31880535 GO_REF:0000107 GO_REF:0000117 MGI:6393026 NCBI chr12:22,411,130...22,417,744
Ensembl chr12:22,411,587...22,417,736 		JBrowse link
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,610...35,323,356 		JBrowse link
G SAMD8 sterile alpha motif domain containing 8 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr14:77,679,287...77,737,657
Ensembl chr14:77,636,149...77,737,654 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17636
    metabolic process 11038
      nitrogen compound metabolic process 9360
        amide metabolic process 1242
          ceramide metabolic process 101
            ceramide biosynthetic process 67
              ganglioside biosynthetic process + 15
              glycosylceramide biosynthetic process + 7
              isogloboside biosynthetic process 0
              lactosylceramide biosynthetic process 2
              negative regulation of ceramide biosynthetic process + 4
              omega-hydroxyceramide biosynthetic process 1
              positive regulation of ceramide biosynthetic process + 7
              regulation of ceramide biosynthetic process + 12
Path 2
Term Annotations click to browse term
  biological_process 17636
    metabolic process 11038
      primary metabolic process 9851
        lipid metabolic process 1331
          cellular lipid metabolic process 989
            membrane lipid metabolic process 199
              sphingolipid metabolic process 148
                sphingolipid biosynthetic process 97
                  ceramide biosynthetic process 67
                    ganglioside biosynthetic process + 15
                    glycosylceramide biosynthetic process + 7
                    isogloboside biosynthetic process 0
                    lactosylceramide biosynthetic process 2
                    negative regulation of ceramide biosynthetic process + 4
                    omega-hydroxyceramide biosynthetic process 1
                    positive regulation of ceramide biosynthetic process + 7
                    regulation of ceramide biosynthetic process + 12
paths to the root