Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:ceramide biosynthetic process
go back to main search page
Accession:GO:0046513 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.
Synonyms:exact_synonym: ceramide anabolism;   ceramide biosynthesis;   ceramide formation;   ceramide synthesis


show annotations for term's descendants           Sort by:
ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACER3 alkaline ceramidase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:76,860,918...77,026,797
Ensembl chr11:76,860,859...77,026,797 		JBrowse link
G AGK acylglycerol kinase involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:15252046) Ensembl
TreeGrafter
MGI
GO_Central		 PMID:15252046 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:141,551,410...141,655,244
Ensembl chr 7:141,551,278...141,655,244 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:8,072,636...8,087,716
Ensembl chr17:8,072,636...8,087,716 		JBrowse link
G ALOXE3 arachidonate lipoxygenase 3 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:8,095,900...8,118,916
Ensembl chr17:8,095,900...8,119,047 		JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 involved_in IDA (PMID:12764132), (PMID:12815059) UniProt PMID:12764132 PMID:12815059 NCBI chr 8:18,055,992...18,084,961
Ensembl chr 8:18,055,992...18,084,998 		JBrowse link
G ASAH2 N-acylsphingosine amidohydrolase 2 involved_in IMP
IDA		 (PMID:11278489)
(PMID:17475390)		 UniProt PMID:11278489 PMID:17475390 NCBI chr10:50,184,861...50,251,516
Ensembl chr10:50,182,778...50,279,720 		JBrowse link
G CERS1 ceramide synthase 1 involved_in IDA
IEA
IBA
ISS		 (PMID:12105227), (PMID:12869556), (PMID:15823095), (PMID:17548428), (PMID:18541923), (PMID:22922758), (PMID:24782409) UniProt
TreeGrafter
GO_Central
HGNC-UCL
InterPro		 PMID:12105227 PMID:12869556 PMID:15823095 PMID:17548428 PMID:18541923 More... GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000117 GO_REF:0000118 NCBI chr19:18,868,545...18,896,982
Ensembl chr19:18,868,545...18,896,727 		JBrowse link
G CERS2 ceramide synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA		 (PMID:15823095)
(PMID:17977534), (PMID:18165233), (PMID:29632068)		 Ensembl
MGI
TreeGrafter
GO_Central
UniProt
InterPro		 PMID:15823095 PMID:17977534 PMID:18165233 PMID:29632068 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr 1:150,965,186...150,974,835
Ensembl chr 1:150,960,583...150,975,003 		JBrowse link
G CERS3 ceramide synthase 3 involved_in IDA
IBA
IEA
IMP		 (PMID:17977534), (PMID:22038835)
(PMID:23754960)		 UniProt
GO_Central
Ensembl
InterPro		 PMID:17977534 PMID:22038835 PMID:23754960 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr15:100,400,395...100,544,683
Ensembl chr15:100,400,395...100,544,995 		JBrowse link
G CERS4 ceramide synthase 4 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA		 (PMID:12912983), (PMID:15823095)
(PMID:17977534), (PMID:29632068)		 InterPro
MGI
TreeGrafter
GO_Central
UniProt
Ensembl		 PMID:12912983 PMID:15823095 PMID:17977534 PMID:29632068 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr19:8,209,370...8,262,421
Ensembl chr19:8,206,736...8,262,421 		JBrowse link
G CERS5 ceramide synthase 5 involved_in IDA
IBA
IEA		 (PMID:16951403), (PMID:29632068) UniProt
GO_Central
InterPro
Ensembl		 PMID:16951403 PMID:29632068 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr12:50,129,289...50,167,369
Ensembl chr12:50,129,289...50,167,533 		JBrowse link
G CERS6 ceramide synthase 6 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA		 (PMID:15823095)
(PMID:17609214), (PMID:17977534)		 InterPro
MGI
GO_Central
UniProt		 PMID:15823095 PMID:17609214 PMID:17977534 GO_REF:0000002 GO_REF:0000033 GO_REF:0000117 NCBI chr 2:168,456,272...168,775,134
Ensembl chr 2:168,456,249...168,775,134 		JBrowse link
G CLN8 CLN8 transmembrane ER and ERGIC protein involved_in NAS (PMID:12151215) UniProt PMID:12151215 NCBI chr 8:1,753,059...1,786,570
Ensembl chr 8:1,755,778...1,801,711 		JBrowse link
G CYP4F22 cytochrome P450 family 4 subfamily F member 22 involved_in IMP
IEA
IBA		 (PMID:26056268) UniProt
TreeGrafter
GO_Central		 PMID:26056268 GO_REF:0000033 GO_REF:0000118 NCBI chr19:15,508,525...15,552,317
Ensembl chr19:15,508,525...15,552,317 		JBrowse link
G DEGS1 delta 4-desaturase, sphingolipid 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:22984457) GO_Central
MGI		 PMID:22984457 GO_REF:0000033 NCBI chr 1:224,183,240...224,193,441
Ensembl chr 1:224,175,756...224,193,441 		JBrowse link
G DEGS2 delta 4-desaturase, sphingolipid 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:100,143,957...100,166,886
Ensembl chr14:100,143,957...100,159,645 		JBrowse link
G ELOVL1 ELOVL fatty acid elongase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:43,363,401...43,368,011
Ensembl chr 1:43,363,398...43,368,074 		JBrowse link
G FA2H fatty acid 2-hydroxylase involved_in IDA
IEA		 (PMID:15337768) UniProt
Ensembl		 PMID:15337768 GO_REF:0000107 NCBI chr16:74,712,969...74,774,820
Ensembl chr16:74,712,955...74,774,831 		JBrowse link
G GBA1 glucosylceramidase beta 1 involved_in IMP (PMID:19279011) BHF-UCL PMID:19279011 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G P2RX1 purinergic receptor P2X 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16325464) Ensembl
MGI		 PMID:16325464 GO_REF:0000107 NCBI chr17:3,896,592...3,916,465
Ensembl chr17:3,896,592...3,916,476 		JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16325464) Ensembl
MGI		 PMID:16325464 GO_REF:0000107 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032 		JBrowse link
G PNPLA1 patatin like phospholipase domain containing 1 involved_in IMP
IEA		 (PMID:27751867) UniProt
Ensembl		 PMID:27751867 GO_REF:0000107 NCBI chr 6:36,243,168...36,313,955
Ensembl chr 6:36,243,203...36,313,955 		JBrowse link
G SAMD8 sterile alpha motif domain containing 8 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA		 (PMID:25667419)
(PMID:25605874)
(PMID:25605874), (PMID:25667419)
(PMID:19506037)		 Ensembl
MGI
TreeGrafter
GO_Central
UniProt		 PMID:19506037 PMID:25605874 PMID:25667419 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr10:75,099,593...75,182,123
Ensembl chr10:75,099,586...75,182,123 		JBrowse link
G SGMS1 sphingomyelin synthase 1 acts_upstream_of_or_within
involved_in		 IDA
IBA
IEA		 (PMID:25605874) MGI
GO_Central
TreeGrafter
Ensembl		 PMID:25605874 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr10:50,305,600...50,625,184
Ensembl chr10:50,305,586...50,625,163 		JBrowse link
G SGMS2 sphingomyelin synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:25605874) Ensembl
MGI
GO_Central		 PMID:25605874 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:107,824,563...107,915,047
Ensembl chr 4:107,824,563...107,915,047 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in ISO
IEA
IBA
IDA
IMP		 (PMID:17303575), (PMID:18815062), (PMID:20807762), (PMID:33163980)
(PMID:19279011), (PMID:8706124)		 RGD
TreeGrafter
GO_Central
Ensembl
UniProt
BHF-UCL		 PMID:8706124 PMID:17261082 PMID:17303575 PMID:18815062 PMID:19279011 More... GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 RGD:1601344 NCBI chr11:6,390,474...6,394,996
Ensembl chr11:6,390,440...6,394,998 		JBrowse link
G SMPD2 sphingomyelin phosphodiesterase 2 involved_in ISO
IBA		 RGD
GO_Central		 PMID:12473648 GO_REF:0000033 RGD:1581395 NCBI chr 6:109,440,724...109,443,919
Ensembl chr 6:109,440,724...109,443,919 		JBrowse link
G SMPD4 sphingomyelin phosphodiesterase 4 involved_in IDA
IBA
IEA		 (PMID:16517606), (PMID:25180167) BHF-UCL
GO_Central
Ensembl		 PMID:16517606 PMID:25180167 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:130,151,392...130,181,757
Ensembl chr 2:130,151,392...130,182,750 		JBrowse link
G SMPD5 sphingomyelin phosphodiesterase 5 (pseudogene) involved_in ISO (MGI:6450238|PMID:21183079) UniProt PMID:21183079 MGI:6450238 NCBI chr 8:144,049,398...144,050,059
Ensembl chr 8:144,049,079...144,051,203 		JBrowse link
G SPTLC1 serine palmitoyltransferase long chain base subunit 1 acts_upstream_of_or_within
involved_in		 IDA
IBA
IEA		 (PMID:25691431) MGI
GO_Central
TreeGrafter
Ensembl		 PMID:25691431 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:92,031,147...92,115,413
Ensembl chr 9:92,000,087...92,115,413 		JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 involved_in
acts_upstream_of_or_within		 IEA
IBA
IDA		 (PMID:25691431) Ensembl
GO_Central
MGI		 PMID:25691431 GO_REF:0000033 GO_REF:0000107 NCBI chr14:77,505,997...77,616,637
Ensembl chr14:77,505,997...77,616,637 		JBrowse link
G SPTLC3 serine palmitoyltransferase long chain base subunit 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr20:13,008,972...13,169,103
Ensembl chr20:13,008,972...13,169,103 		JBrowse link
G SPTSSA serine palmitoyltransferase small subunit A acts_upstream_of_or_within
involved_in		 IDA
IBA		 (PMID:25691431) MGI
GO_Central		 PMID:25691431 GO_REF:0000033 NCBI chr14:34,432,788...34,462,240
Ensembl chr14:34,432,788...34,462,240 		JBrowse link
G SPTSSB serine palmitoyltransferase small subunit B involved_in
acts_upstream_of_or_within		 IEA
IBA
ISS		 Ensembl
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:161,344,798...161,371,517
Ensembl chr 3:161,344,798...161,372,880 		JBrowse link
G TLCD3B TLC domain containing 3B involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:23275342) Ensembl
MGI
GO_Central
TreeGrafter		 PMID:23275342 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr16:30,024,427...30,053,040
Ensembl chr16:30,024,427...30,052,978 		JBrowse link
galactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3GALT1 beta-1,3-galactosyltransferase 1 involved_in IDA (PMID:9582303) BHF-UCL PMID:9582303 NCBI chr 2:167,293,001...167,874,045
Ensembl chr 2:167,293,001...167,874,045 		JBrowse link
G B3GALT2 beta-1,3-galactosyltransferase 2 involved_in IDA (PMID:9582303) BHF-UCL PMID:9582303 NCBI chr 1:193,178,730...193,186,613
Ensembl chr 1:193,178,730...193,186,613 		JBrowse link
G B4GALT3 beta-1,4-galactosyltransferase 3 involved_in IDA
IBA
IEA		 (PMID:9405390) BHF-UCL
GO_Central
TreeGrafter		 PMID:9405390 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:161,171,310...161,177,968
Ensembl chr 1:161,171,310...161,177,968 		JBrowse link
G FA2H fatty acid 2-hydroxylase involved_in IEA
ISS		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000041 GO_REF:0000107 NCBI chr16:74,712,969...74,774,820
Ensembl chr16:74,712,955...74,774,831 		JBrowse link
G GAL3ST1 galactose-3-O-sulfotransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:10727929) Ensembl
MGI
GO_Central
TreeGrafter		 PMID:10727929 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr22:30,554,635...30,574,665
Ensembl chr22:30,554,635...30,574,665 		JBrowse link
G UGT8 UDP glycosyltransferase 8 involved_in IEA
IBA
ISS		 Ensembl
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000041 GO_REF:0000107 NCBI chr 4:114,598,402...114,678,225
Ensembl chr 4:114,598,770...114,678,225 		JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3GALT4 beta-1,3-galactosyltransferase 4 involved_in IDA (PMID:9582303) BHF-UCL PMID:9582303 NCBI chr 6:33,277,123...33,278,825
Ensembl chr 6:33,277,123...33,284,832 		JBrowse link
G B4GALNT1 beta-1,4-N-acetyl-galactosaminyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
IDA
IMP		 (PMID:10021458)
(PMID:7487055), (PMID:7890749)
(PMID:1601877)		 Ensembl
MGI
TreeGrafter
GO_Central
UniProt		 PMID:1601877 PMID:7487055 PMID:7890749 PMID:10021458 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:57,623,409...57,633,201
Ensembl chr12:57,623,409...57,633,239 		JBrowse link
G ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 involved_in IC (PMID:9822625) UniProt PMID:9822625 NCBI chr 2:85,837,120...85,889,034
Ensembl chr 2:85,837,120...85,905,199 		JBrowse link
G ST6GALNAC3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:76,074,746...76,637,339
Ensembl chr 1:76,074,746...76,634,603 		JBrowse link
G ST6GALNAC4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 9:127,907,886...127,917,041
Ensembl chr 9:127,907,886...127,917,041 		JBrowse link
G ST6GALNAC5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:76,867,480...77,067,546
Ensembl chr 1:76,867,480...77,067,546 		JBrowse link
G ST6GALNAC6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA
IEA		 (PMID:10702226) BHF-UCL
MGI
GO_Central
TreeGrafter
Ensembl		 PMID:10702226 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:127,885,321...127,906,616
Ensembl chr 9:127,885,321...127,905,408 		JBrowse link
G ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in IDA (PMID:10766765) BHF-UCL PMID:10766765 NCBI chr15:92,393,881...92,468,728
Ensembl chr15:92,393,881...92,468,728 		JBrowse link
G ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in IDA
IEA		 (PMID:10766765) BHF-UCL
Ensembl		 PMID:10766765 GO_REF:0000107 NCBI chr18:57,352,557...57,368,931
Ensembl chr18:57,352,557...57,371,731 		JBrowse link
G ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in IDA (PMID:10766765) BHF-UCL PMID:10766765 NCBI chr 5:100,806,933...100,903,282
Ensembl chr 5:100,806,933...100,903,282 		JBrowse link
G ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in IEA
ISS		 (PMID:11980897) Ensembl
BHF-UCL		 PMID:11980897 GO_REF:0000107 NCBI chr10:17,315,421...17,454,595
Ensembl chr10:17,315,421...17,454,595 		JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4GALT5 beta-1,4-galactosyltransferase 5 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:49,632,945...49,713,878
Ensembl chr20:49,632,945...49,713,878 		JBrowse link
G B4GALT6 beta-1,4-galactosyltransferase 6 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr18:31,622,246...31,724,641
Ensembl chr18:31,622,246...31,685,836 		JBrowse link
G C20orf173 chromosome 20 open reading frame 173 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr20:35,520,741...35,529,652
Ensembl chr20:35,523,186...35,529,652 		JBrowse link
G ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in IDA
IBA
IEA		 (PMID:8027041) UniProt
GO_Central
Ensembl		 PMID:8027041 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 8:133,454,848...133,571,887
Ensembl chr 8:133,454,848...133,571,926 		JBrowse link
G ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in IEA
IBA
IDA		 (PMID:8920913) Ensembl
GO_Central
TreeGrafter
UniProt		 PMID:8920913 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr16:70,375,977...70,439,100
Ensembl chr16:70,375,977...70,439,237 		JBrowse link
G ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:43,707,536...43,931,159
Ensembl chr 1:43,705,824...43,931,165 		JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FA2H fatty acid 2-hydroxylase involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:74,712,969...74,774,820
Ensembl chr16:74,712,955...74,774,831 		JBrowse link
G UGCG UDP-glucose ceramide glucosyltransferase involved_in IEA
IBA
IDA		 (PMID:8643456) Ensembl
GO_Central
UniProt		 PMID:8643456 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:111,896,814...111,935,369
Ensembl chr 9:111,896,814...111,935,369 		JBrowse link
lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4GALT4 beta-1,4-galactosyltransferase 4 involved_in IDA (PMID:9792633) UniProt PMID:9792633 NCBI chr 3:119,211,742...119,240,878
Ensembl chr 3:119,211,732...119,240,946 		JBrowse link
G B4GALT6 beta-1,4-galactosyltransferase 6 involved_in IDA (PMID:10320813) BHF-UCL PMID:10320813 NCBI chr18:31,622,246...31,724,641
Ensembl chr18:31,622,246...31,685,836 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within IMP (PMID:25691431) MGI PMID:25691431 NCBI chr 2:189,763,859...189,784,339
Ensembl chr 2:189,770,267...189,784,364 		JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within IMP (PMID:25691431) MGI PMID:25691431 NCBI chr12:55,818,041...55,821,879
Ensembl chr12:55,818,041...55,821,879 		JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within
involved_in		 IMP
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr17:39,921,041...39,927,601
Ensembl chr17:39,921,041...39,927,601 		JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA
IDA		 (PMID:16118219) Ensembl
UniProt		 PMID:16118219 GO_REF:0000107 NCBI chr17:76,383,204...76,387,855
Ensembl chr17:76,376,584...76,387,860 		JBrowse link
negative regulation of glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in NAS (PMID:11165240) UniProt PMID:11165240 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
omega-hydroxyceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PNPLA1 patatin like phospholipase domain containing 1 involved_in IEA
IMP		 (PMID:28248318) Ensembl
UniProt		 PMID:28248318 GO_REF:0000107 NCBI chr 6:36,243,168...36,313,955
Ensembl chr 6:36,243,203...36,313,955 		JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCN1 cellular communication network factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19364818) Ensembl
MGI		 PMID:19364818 GO_REF:0000107 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589 		JBrowse link
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS UniProt GO_REF:0000024 NCBI chr17:79,730,943...79,742,219
Ensembl chr17:79,730,943...79,742,219 		JBrowse link
G PLA2G6 phospholipase A2 group VI involved_in ISO
IBA
IEA		 RGD
GO_Central
TreeGrafter		 PMID:18936091 GO_REF:0000033 GO_REF:0000118 RGD:6482750 NCBI chr22:38,111,495...38,181,830
Ensembl chr22:38,111,495...38,214,778 		JBrowse link
G PRKCD protein kinase C delta involved_in IMP (PMID:19279011) BHF-UCL PMID:19279011 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717 		JBrowse link
G SIRT3 sirtuin 3 involved_in ISS UniProt GO_REF:0000024 NCBI chr11:215,030...236,931
Ensembl chr11:215,030...236,931 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 ISO RGD PMID:20096352 RGD:10041064 NCBI chr16:68,358,327...68,448,508
Ensembl chr16:68,358,327...68,448,508 		JBrowse link
G SPHK2 sphingosine kinase 2 involved_in IEA
IDA		 (PMID:16118219) Ensembl
UniProt		 PMID:16118219 GO_REF:0000107 NCBI chr19:48,619,506...48,630,405
Ensembl chr19:48,619,291...48,630,717 		JBrowse link
G ZNF750 zinc finger protein 750 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:37115925) Ensembl
MGI		 PMID:37115925 GO_REF:0000107 NCBI chr17:82,829,434...82,840,022
Ensembl chr17:82,829,434...82,840,022 		JBrowse link
regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:31880535) UniProt
MGI
Ensembl		 PMID:31880535 GO_REF:0000107 GO_REF:0000117 NCBI chr 2:189,763,859...189,784,339
Ensembl chr 2:189,770,267...189,784,364 		JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 involved_in IEA UniProt GO_REF:0000117 NCBI chr12:55,818,041...55,821,879
Ensembl chr12:55,818,041...55,821,879 		JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:31880535) Ensembl
MGI
UniProt		 PMID:31880535 GO_REF:0000107 GO_REF:0000117 NCBI chr17:39,921,041...39,927,601
Ensembl chr17:39,921,041...39,927,601 		JBrowse link
G PRKCD protein kinase C delta involved_in IDA (PMID:17303575) UniProt PMID:17303575 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717 		JBrowse link
G SAMD8 sterile alpha motif domain containing 8 involved_in IDA (PMID:19506037) UniProt PMID:19506037 NCBI chr10:75,099,593...75,182,123
Ensembl chr10:75,099,586...75,182,123 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    metabolic process 12464
      amide metabolic process 508
        amide biosynthetic process 170
          ceramide biosynthetic process 72
            ganglioside biosynthetic process + 17
            glycosylceramide biosynthetic process + 8
            isogloboside biosynthetic process 0
            lactosylceramide biosynthetic process 2
            negative regulation of ceramide biosynthetic process + 5
            omega-hydroxyceramide biosynthetic process 1
            positive regulation of ceramide biosynthetic process + 8
            regulation of ceramide biosynthetic process + 14
Path 2
Term Annotations click to browse term
  biological_process 19669
    metabolic process 12464
      organic substance metabolic process 11967
        lipid metabolic process 1530
          cellular lipid metabolic process 1120
            membrane lipid metabolic process 226
              sphingolipid metabolic process 177
                ceramide metabolic process 114
                  ceramide biosynthetic process 72
                    ganglioside biosynthetic process + 17
                    glycosylceramide biosynthetic process + 8
                    isogloboside biosynthetic process 0
                    lactosylceramide biosynthetic process 2
                    negative regulation of ceramide biosynthetic process + 5
                    omega-hydroxyceramide biosynthetic process 1
                    positive regulation of ceramide biosynthetic process + 8
                    regulation of ceramide biosynthetic process + 14
paths to the root