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ONTOLOGY REPORT - ANNOTATIONS

Term:ceramide biosynthetic process
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Accession:GO:0046513 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.
Synonyms:exact_synonym: ceramide anabolism;   ceramide biosynthesis;   ceramide formation;   ceramide synthesis

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ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agk acylglycerol kinase acts_upstream_of_or_within ISO (MGI:3054595|PMID:15252046) MGI PMID:15252046 MGI:3054595 NCBI chrNW_004955494:1,924,026...2,041,914
Ensembl chrNW_004955494:1,924,026...2,021,778 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in ISO (MGI:3789553|PMID:17403930) UniProt PMID:17403930 MGI:3789553 NCBI chrNW_004955467:8,876,186...8,887,980
Ensembl chrNW_004955467:8,876,027...8,888,033 		JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 involved_in ISO (MGI:5488571|PMID:22832496) UniProt PMID:22832496 MGI:5488571 NCBI chrNW_004955467:8,844,805...8,869,230
Ensembl chrNW_004955467:8,844,805...8,869,964 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISO (PMID:12764132), (PMID:12815059) UniProt PMID:12764132 PMID:12815059 NCBI chrNW_004955552:1,623,263...1,660,285
Ensembl chrNW_004955552:1,623,738...1,659,086 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO (PMID:17475390)
(MGI:6274955|PMID:21613224)
PMID:15123644
PMID:11278489
(PMID:11278489)		 UniProt PMID:11278489 PMID:15123644 PMID:17475390 PMID:21613224 MGI:6274955 RGD:13838793 RGD:13838803 NCBI chrNW_004955425:5,840,355...5,931,891
Ensembl chrNW_004955425:5,840,355...5,931,891 		JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO (MGI:3696321|PMID:16951403), (MGI:3764760|PMID:17977534), (MGI:5755322|PMID:26620563)
(MGI:5008665|PMID:21625621), (MGI:6380950|PMID:30605666)
(PMID:12105227), (PMID:12869556), (PMID:15823095), (PMID:17548428), (PMID:18541923), (PMID:22922758), (PMID:24782409)		 UniProt PMID:12105227 PMID:12869556 PMID:15823095 PMID:16951403 PMID:17548428 More... MGI:3696321 MGI:3764760 MGI:5008665 MGI:5755322 MGI:6380950 NCBI chrNW_004955524:2,788,672...2,798,068
Ensembl chrNW_004955524:2,788,653...2,796,370 		JBrowse link
G Cers2 ceramide synthase 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:17977534), (PMID:18165233), (PMID:29632068)
(MGI:4421488|PMID:19801672)
(MGI:3696894|PMID:15823095)
(MGI:5755322|PMID:26620563)		 UniProt
MGI		 PMID:15823095 PMID:17977534 PMID:18165233 PMID:19801672 PMID:26620563 More... MGI:3696894 MGI:4421488 MGI:5755322 NCBI chrNW_004955588:338,381...342,139
Ensembl chrNW_004955588:336,083...342,599 		JBrowse link
G Cers3 ceramide synthase 3 involved_in ISO (PMID:17977534), (PMID:22038835)
(MGI:5303015|PMID:22038835)
(PMID:23754960)		 UniProt PMID:17977534 PMID:22038835 PMID:23754960 MGI:5303015 NCBI chrNW_004955416:27,461,950...27,577,145
Ensembl chrNW_004955416:27,461,335...27,536,188 		JBrowse link
G Cers4 ceramide synthase 4 involved_in
acts_upstream_of_or_within		 ISO (PMID:17977534), (PMID:29632068)
(MGI:2679796|PMID:12912983), (MGI:3696894|PMID:15823095)		 UniProt
MGI		 PMID:12912983 PMID:15823095 PMID:17977534 PMID:29632068 MGI:2679796 MGI:3696894 NCBI chrNW_004955563:1,100,410...1,105,662
Ensembl chrNW_004955563:1,100,787...1,124,258 		JBrowse link
G Cers5 ceramide synthase 5 involved_in ISO (PMID:16951403), (PMID:29632068)
(MGI:3696624|PMID:16100120), (MGI:3722529|PMID:17609214), (MGI:3764760|PMID:17977534)		 UniProt PMID:16100120 PMID:16951403 PMID:17609214 PMID:17977534 PMID:29632068 MGI:3696624 MGI:3722529 MGI:3764760 NCBI chrNW_004955547:697,089...728,573
Ensembl chrNW_004955547:697,089...726,139 		JBrowse link
G Cers6 ceramide synthase 6 involved_in
acts_upstream_of_or_within		 ISO (PMID:17609214), (PMID:17977534)
(MGI:3696894|PMID:15823095)
(MGI:5755322|PMID:26620563)
(MGI:5513027|PMID:23760501)		 UniProt
MGI		 PMID:15823095 PMID:17609214 PMID:17977534 PMID:23760501 PMID:26620563 MGI:3696894 MGI:5513027 MGI:5755322 NCBI chrNW_004955449:5,636,678...5,920,377
Ensembl chrNW_004955449:5,642,341...5,920,573 		JBrowse link
G Degs1 delta 4-desaturase, sphingolipid 1 acts_upstream_of_or_within ISO (MGI:5466789|PMID:22984457) MGI PMID:22984457 MGI:5466789 NCBI chrNW_004955520:1,139,568...1,143,149
Ensembl chrNW_004955520:1,135,563...1,143,192 		JBrowse link
G Degs2 delta 4-desaturase, sphingolipid 2 acts_upstream_of_or_within ISO (MGI:3694278|PMID:16571104) MGI PMID:16571104 MGI:3694278 NCBI chrNW_004955438:21,300,118...21,313,330
Ensembl chrNW_004955438:21,300,118...21,313,330 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 involved_in ISO (MGI:5532629|PMID:23689133) UniProt PMID:23689133 MGI:5532629 NCBI chrNW_004955537:2,945,509...2,950,146
Ensembl chrNW_004955537:2,945,509...2,950,146 		JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in ISO (PMID:15337768)
(MGI:6245295|PMID:22517924)		 UniProt PMID:15337768 PMID:22517924 MGI:6245295 NCBI chrNW_004955484:2,726,496...2,775,763
Ensembl chrNW_004955484:2,726,362...2,775,903 		JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in ISO (PMID:19279011) BHF-UCL PMID:19279011 NCBI chrNW_004955545:1,682,097...1,689,373
Ensembl chrNW_004955545:1,682,097...1,689,376 		JBrowse link
G LOC102004294 cytochrome P450 4F22 involved_in ISO (PMID:26056268) UniProt PMID:26056268 NCBI chrNW_004955495:7,730,881...7,763,684
Ensembl chrNW_004955495:7,730,826...7,763,684 		JBrowse link
G P2rx1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO (MGI:3640029|PMID:16325464) MGI PMID:16325464 MGI:3640029 NCBI chrNW_004955467:12,955,663...12,971,547
Ensembl chrNW_004955467:12,955,672...12,971,547 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (MGI:3640029|PMID:16325464) MGI PMID:16325464 MGI:3640029 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926 		JBrowse link
G Pnpla1 patatin like phospholipase domain containing 1 involved_in ISO (PMID:27751867)
(MGI:5882269|PMID:27751867)		 UniProt PMID:27751867 MGI:5882269 NCBI chrNW_004955437:4,008,814...4,047,895
Ensembl chrNW_004955437:4,008,545...4,048,033 		JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in
acts_upstream_of_or_within		 ISO (PMID:19506037)
(MGI:5707904|PMID:25667419)
(MGI:5632043|PMID:25605874)
(MGI:5632043|PMID:25605874), (MGI:5707904|PMID:25667419)		 UniProt
MGI		 PMID:19506037 PMID:25605874 PMID:25667419 MGI:5632043 MGI:5707904 NCBI chrNW_004955437:16,900,756...16,969,042
Ensembl chrNW_004955437:16,900,688...16,969,042 		JBrowse link
G Sgms1 sphingomyelin synthase 1 acts_upstream_of_or_within ISO (MGI:5632043|PMID:25605874)
(PMID:25605874)		 MGI PMID:25605874 MGI:5632043 NCBI chrNW_004955425:5,507,905...5,819,357
Ensembl chrNW_004955425:5,784,751...5,822,488 		JBrowse link
G Sgms2 sphingomyelin synthase 2 acts_upstream_of_or_within ISO (MGI:5632043|PMID:25605874) MGI PMID:25605874 MGI:5632043 NCBI chrNW_004955496:1,909,347...1,955,004
Ensembl chrNW_004955496:1,905,517...1,947,009 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 involved_in ISO (PMID:17303575), (PMID:18815062), (PMID:20807762), (PMID:33163980)
(MGI:7327228|PMID:35705808)
(MGI:82530|PMID:8706124)
(PMID:19279011), (PMID:8706124)		 RGD
UniProt
BHF-UCL		 PMID:8706124 PMID:17261082 PMID:17303575 PMID:18815062 PMID:19279011 More... MGI:7327228 MGI:82530 RGD:1601344 NCBI chrNW_004955414:22,117,929...22,121,744
Ensembl chrNW_004955414:22,117,930...22,121,744 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 ISO RGD PMID:12473648 RGD:1581395 NCBI chrNW_004955411:34,481,431...34,484,423
Ensembl chrNW_004955411:34,481,823...34,484,406 		JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 involved_in ISO (PMID:16517606), (PMID:25180167)
(MGI:6450503|PMID:25180167)		 BHF-UCL
UniProt		 PMID:16517606 PMID:25180167 MGI:6450503 NCBI chrNW_004955442:19,184,794...19,210,999
Ensembl chrNW_004955442:19,184,794...19,210,999 		JBrowse link
G Sptlc1 serine palmitoyltransferase long chain base subunit 1 acts_upstream_of_or_within ISO (MGI:3814228|PMID:16216550)
(PMID:25691431)		 MGI PMID:16216550 PMID:25691431 MGI:3814228 NCBI chrNW_004955515:57,711...161,012
Ensembl chrNW_004955515:57,711...161,611 		JBrowse link
G Sptlc2 serine palmitoyltransferase long chain base subunit 2 acts_upstream_of_or_within ISO (MGI:3814228|PMID:16216550)
(PMID:25691431)		 MGI PMID:16216550 PMID:25691431 MGI:3814228 NCBI chrNW_004955438:1,385,431...1,491,534
Ensembl chrNW_004955438:1,385,431...1,491,578 		JBrowse link
G Sptssa serine palmitoyltransferase small subunit A acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chrNW_004955409:26,460,208...26,460,854 JBrowse link
G Sptssb serine palmitoyltransferase small subunit B acts_upstream_of_or_within ISO (MGI:5689923|PMID:26438849) MGI PMID:26438849 MGI:5689923 NCBI chrNW_004955448:11,756,766...11,791,418
Ensembl chrNW_004955448:11,756,766...11,790,368 		JBrowse link
G Tlcd3b TLC domain containing 3B acts_upstream_of_or_within ISO (MGI:5490837|PMID:23275342) MGI PMID:23275342 MGI:5490837 NCBI chrNW_004955493:6,929,477...6,940,109
Ensembl chrNW_004955493:6,929,477...6,942,227 		JBrowse link
galactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt1 beta-1,3-galactosyltransferase 1 involved_in ISO (PMID:9582303) BHF-UCL PMID:9582303 NCBI chrNW_004955449:6,452,189...7,007,329
Ensembl chrNW_004955449:6,452,189...6,553,158 		JBrowse link
G B3galt2 beta-1,3-galactosyltransferase 2 involved_in ISO (PMID:9582303) BHF-UCL PMID:9582303 NCBI chrNW_004955406:30,603,238...30,610,822
Ensembl chrNW_004955406:30,603,238...30,610,822 		JBrowse link
G B4galt3 beta-1,4-galactosyltransferase 3 involved_in ISO (PMID:9405390) BHF-UCL PMID:9405390 NCBI chrNW_004955468:12,934,521...12,945,435
Ensembl chrNW_004955468:12,932,059...12,940,723 		JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in ISO PMID:17901466
(MGI:3826747|PMID:18815260)
(MGI:3696647|PMID:15658937)		 UniProt PMID:15658937 PMID:17901466 PMID:18815260 MGI:3696647 MGI:3826747 RGD:13825191 NCBI chrNW_004955484:2,726,496...2,775,763
Ensembl chrNW_004955484:2,726,362...2,775,903 		JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 acts_upstream_of_or_within ISO (MGI:1355015|PMID:10727929) MGI PMID:10727929 MGI:1355015 NCBI chrNW_004955455:4,771,378...4,794,085
Ensembl chrNW_004955455:4,771,346...4,784,142 		JBrowse link
G Ugt8 UDP glycosyltransferase 8 involved_in ISO PMID:8713090 UniProt PMID:8713090 RGD:39458006 NCBI chrNW_004955428:24,800,854...24,864,904
Ensembl chrNW_004955428:24,800,854...24,865,378 		JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt4 beta-1,3-galactosyltransferase 4 involved_in ISO (PMID:9582303) BHF-UCL PMID:9582303 NCBI chrNW_004955437:1,839,707...1,840,516 JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyltransferase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:7487055), (PMID:7890749)
(MGI:1331265|PMID:10021458)
(MGI:83232|PMID:8855236)
PMID:3140234
(PMID:1601877)		 UniProt
MGI		 PMID:1601877 PMID:3140234 PMID:7487055 PMID:7890749 PMID:8855236 More... MGI:1331265 MGI:83232 RGD:21201261 NCBI chrNW_004955458:5,351,924...5,361,755
Ensembl chrNW_004955458:5,350,244...5,360,965 		JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 acts_upstream_of_or_within ISO (MGI:1354410|PMID:10702226) MGI PMID:10702226 MGI:1354410 NCBI chrNW_004955419:771,721...792,756
Ensembl chrNW_004955419:772,837...796,724 		JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in ISO (PMID:10766765) BHF-UCL PMID:10766765 NCBI chrNW_004955416:20,697,651...20,763,975
Ensembl chrNW_004955416:20,697,651...20,767,112 		JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in ISO (PMID:10766765) BHF-UCL PMID:10766765 NCBI chrNW_004955402:41,713,969...41,732,889
Ensembl chrNW_004955402:41,713,573...41,723,749 		JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in ISO (PMID:10766765) BHF-UCL PMID:10766765 NCBI chrNW_004955418:12,590,744...12,679,677
Ensembl chrNW_004955418:12,590,536...12,679,677 		JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in ISO (MGI:2182536|PMID:11980897) BHF-UCL PMID:11980897 MGI:2182536 NCBI chrNW_004955429:10,538,660...10,660,493
Ensembl chrNW_004955429:10,538,661...10,658,008 		JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt5 beta-1,4-galactosyltransferase 5 involved_in ISO (MGI:6196231|PMID:30114188) UniProt PMID:30114188 MGI:6196231 NCBI chrNW_004955445:8,471,684...8,559,672
Ensembl chrNW_004955445:8,534,220...8,559,672 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISO (MGI:6196231|PMID:30114188) UniProt PMID:30114188 MGI:6196231 NCBI chrNW_004955402:18,945,013...19,024,132
Ensembl chrNW_004955402:18,942,872...19,024,132 		JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in ISO (PMID:8027041)
(MGI:65558|PMID:8144500)		 UniProt PMID:8027041 PMID:8144500 MGI:65558 NCBI chrNW_004955461:7,960,901...8,036,221
Ensembl chrNW_004955461:7,960,690...7,976,183 		JBrowse link
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in ISO (PMID:8920913)
(MGI:6467685|PMID:22735313)
(MGI:65558|PMID:8144500)		 UniProt PMID:8144500 PMID:8920913 PMID:22735313 MGI:6467685 MGI:65558 RGD:68307 NCBI chrNW_004955484:3,176,214...3,230,433
Ensembl chrNW_004955484:3,177,104...3,230,433 		JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in ISO (MGI:6467685|PMID:22735313) UniProt PMID:22735313 MGI:6467685 NCBI chrNW_004955537:3,258,076...3,458,742
Ensembl chrNW_004955537:3,258,076...3,458,742 		JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fa2h fatty acid 2-hydroxylase involved_in ISO (MGI:5285470|PMID:21628453) UniProt PMID:21628453 MGI:5285470 NCBI chrNW_004955484:2,726,496...2,775,763
Ensembl chrNW_004955484:2,726,362...2,775,903 		JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase involved_in ISO (PMID:8643456)
(MGI:2180222|PMID:10430909), (MGI:3603060|PMID:16109770), (MGI:5448789|PMID:22851168), (MGI:5510915|PMID:23748427)		 UniProt PMID:8643456 PMID:10430909 PMID:16109770 PMID:22851168 PMID:23748427 MGI:2180222 MGI:3603060 MGI:5448789 MGI:5510915 NCBI chrNW_004955419:15,417,468...15,451,936
Ensembl chrNW_004955419:15,416,796...15,451,936 		JBrowse link
lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt4 beta-1,4-galactosyltransferase 4 involved_in ISO (PMID:9792633) UniProt PMID:9792633 NCBI chrNW_004955427:18,964,578...18,982,090
Ensembl chrNW_004955427:18,963,396...18,985,479 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISO (PMID:10320813) BHF-UCL PMID:10320813 NCBI chrNW_004955402:18,945,013...19,024,132
Ensembl chrNW_004955402:18,942,872...19,024,132 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chrNW_004955403:9,100,516...9,113,230
Ensembl chrNW_004955403:9,100,516...9,113,223 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chrNW_004955458:3,451,434...3,454,259
Ensembl chrNW_004955458:3,451,021...3,457,086 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within ISO (MGI:5638294|PMID:25691431)
(PMID:25691431)		 MGI PMID:25691431 MGI:5638294 NCBI chrNW_004955451:14,621,565...14,627,556
Ensembl chrNW_004955451:14,621,399...14,642,763 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO (PMID:16118219)
(MGI:6294167|PMID:16118219)		 UniProt PMID:16118219 MGI:6294167 NCBI chrNW_004955506:5,902,079...5,906,639
Ensembl chrNW_004955506:5,902,345...5,904,988 		JBrowse link
omega-hydroxyceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpla1 patatin like phospholipase domain containing 1 involved_in ISO (PMID:28248318)
(MGI:5888934|PMID:28248300)		 UniProt PMID:28248300 PMID:28248318 MGI:5888934 NCBI chrNW_004955437:4,008,814...4,047,895
Ensembl chrNW_004955437:4,008,545...4,048,033 		JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn1 cellular communication network factor 1 acts_upstream_of_or_within ISO (MGI:3849354|PMID:19364818) MGI PMID:19364818 MGI:3849354 NCBI chrNW_004955423:8,416,498...8,419,029
Ensembl chrNW_004955423:8,413,725...8,419,166 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (MGI:4947032|PMID:21177474) UniProt PMID:21177474 MGI:4947032 NCBI chrNW_004955506:3,151,133...3,154,613
Ensembl chrNW_004955506:3,151,133...3,154,613 		JBrowse link
G Pla2g6 phospholipase A2 group VI ISO RGD PMID:18936091 RGD:6482750 NCBI chrNW_004955413:24,431,592...24,482,229
Ensembl chrNW_004955413:24,429,589...24,482,537 		JBrowse link
G Prkcd protein kinase C delta involved_in ISO (PMID:19279011) BHF-UCL PMID:19279011 NCBI chrNW_004955430:3,125,066...3,151,857
Ensembl chrNW_004955430:3,124,738...3,153,274 		JBrowse link
G Sirt3 sirtuin 3 involved_in ISO (MGI:5755322|PMID:26620563) UniProt PMID:26620563 MGI:5755322 NCBI chrNW_004955476:11,794,951...11,826,244
Ensembl chrNW_004955476:11,794,951...11,826,237 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 ISO RGD PMID:20096352 RGD:10041064 NCBI chrNW_004955484:8,207,686...8,298,164
Ensembl chrNW_004955484:8,272,572...8,298,144 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (PMID:16118219)
(MGI:6294167|PMID:16118219)		 UniProt PMID:16118219 MGI:6294167 NCBI chrNW_004955559:1,921,479...1,929,450
Ensembl chrNW_004955559:1,917,301...1,928,493 		JBrowse link
regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of ISO (MGI:6393026|PMID:31880535) MGI PMID:31880535 MGI:6393026 NCBI chrNW_004955403:9,100,516...9,113,230
Ensembl chrNW_004955403:9,100,516...9,113,223 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of ISO (MGI:6393026|PMID:31880535) MGI PMID:31880535 MGI:6393026 NCBI chrNW_004955451:14,621,565...14,627,556
Ensembl chrNW_004955451:14,621,399...14,642,763 		JBrowse link
G Prkcd protein kinase C delta involved_in ISO (PMID:17303575) UniProt PMID:17303575 NCBI chrNW_004955430:3,125,066...3,151,857
Ensembl chrNW_004955430:3,124,738...3,153,274 		JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in ISO (PMID:19506037) UniProt PMID:19506037 NCBI chrNW_004955437:16,900,756...16,969,042
Ensembl chrNW_004955437:16,900,688...16,969,042 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12249
    metabolic process 7791
      nitrogen compound metabolic process 6610
        amide metabolic process 767
          ceramide metabolic process 93
            ceramide biosynthetic process 61
              ganglioside biosynthetic process + 12
              glycosylceramide biosynthetic process + 7
              isogloboside biosynthetic process 0
              lactosylceramide biosynthetic process 2
              negative regulation of ceramide biosynthetic process + 4
              omega-hydroxyceramide biosynthetic process 1
              positive regulation of ceramide biosynthetic process + 7
              regulation of ceramide biosynthetic process + 12
Path 2
Term Annotations click to browse term
  biological_process 12249
    metabolic process 7791
      primary metabolic process 6964
        lipid metabolic process 965
          cellular lipid metabolic process 731
            membrane lipid metabolic process 161
              sphingolipid metabolic process 123
                sphingolipid biosynthetic process 80
                  ceramide biosynthetic process 61
                    ganglioside biosynthetic process + 12
                    glycosylceramide biosynthetic process + 7
                    isogloboside biosynthetic process 0
                    lactosylceramide biosynthetic process 2
                    negative regulation of ceramide biosynthetic process + 4
                    omega-hydroxyceramide biosynthetic process 1
                    positive regulation of ceramide biosynthetic process + 7
                    regulation of ceramide biosynthetic process + 12
paths to the root