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ONTOLOGY REPORT - ANNOTATIONS

Term:S-adenosylmethionine metabolic process
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Accession:GO:0046500 term browser browse the term
Definition:The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
Synonyms:exact_synonym: S-adenosyl methionine metabolic process;   S-adenosyl methionine metabolism;   S-adenosylmethionine metabolism;   SAM metabolic process


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S-adenosylmethionine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMD1 adenosylmethionine decarboxylase 1 ISO RGD PMID:1415709 PMID:21048303 RGD:7242909 RGD:7242912 NCBI chr 1:76,839,448...76,863,745
Ensembl chr 1:76,839,731...76,863,738 		JBrowse link
G BHMT betaine--homocysteine S-methyltransferase NOT|involved_in ISO (PMID:18230605) BHF-UCL PMID:18230605 NCBI chr 2:87,911,093...87,935,252
Ensembl chr 2:87,910,603...87,935,252 		JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:87,866,631...87,882,623
Ensembl chr 2:87,866,621...87,882,716 		JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:3856245 RGD:2301219 NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844 		JBrowse link
G GAMT guanidinoacetate N-methyltransferase ISO RGD PMID:15533043 RGD:1359081 NCBI chr 2:77,076,566...77,079,751
Ensembl chr 2:77,076,566...77,079,759 		JBrowse link
G GNMT glycine N-methyltransferase involved_in IEA
ISS
IBA
ISO		 (PMID:21873635) Ensembl
UniProt
GO_Central
RGD
UniProt
GO_Central		 PMID:12054489 PMID:18501206 PMID:21873635 GO_REF:0000024 GO_REF:0000107 RGD:7242952 RGD:728472 NCBI chr 7:38,038,359...38,041,218
Ensembl chr 7:38,038,358...38,041,217 		JBrowse link
G HNMT histamine N-methyltransferase ISO RGD PMID:15739896 RGD:152985534 NCBI chr15:13,733,412...13,768,106
Ensembl chr15:13,732,680...13,768,199 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO RGD PMID:1201245 RGD:6893692 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820 		JBrowse link
G PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase ISO RGD PMID:8263531 RGD:729481 NCBI chr 1:16,202,859...16,249,879
Ensembl chr 1:16,198,223...16,249,531 		JBrowse link
G PEMT phosphatidylethanolamine N-methyltransferase ISO RGD PMID:8344945 RGD:729486 NCBI chr12:60,880,367...60,919,279 JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APIP APAF1 interacting protein involved_in IEA UniProt
UniProt		 GO_REF:0000104 NCBI chr 2:26,095,020...26,115,462
Ensembl chr 2:26,095,038...26,115,464 		JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA UniProt
UniProt		 GO_REF:0000104 NCBI chr 8:135,775,743...135,802,404
Ensembl chr 8:135,775,745...135,802,388 		JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt
UniProt		 GO_REF:0000104 NCBI chr 2:65,348,609...65,354,892
Ensembl chr 2:65,348,006...65,355,118 		JBrowse link
S-adenosylmethionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNG1 cyclin G1 involved_in IEA UniProt GO_REF:0000041 NCBI chr16:60,349,255...60,356,737
Ensembl chr16:60,349,258...60,356,738 		JBrowse link
G MAT1A methionine adenosyltransferase 1A involved_in IEA
IBA
ISO		 (PMID:21873635) UniProt
GO_Central
UniProt
Ensembl
InterPro
RGD
GO_Central		 PMID:9202427 PMID:10898761 PMID:19497982 PMID:21873635 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 GO_REF:0000117 RGD:1359039 RGD:7242770 RGD:7242777 NCBI chr14:82,109,405...82,126,487
Ensembl chr14:82,107,390...82,127,049 		JBrowse link
G MAT2A methionine adenosyltransferase 2A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2183618|PMID:12023972) UniProt
UniProt
InterPro
MGI
RGD		 PMID:10898761 PMID:12023972 PMID:12029623 GO_REF:0000002 GO_REF:0000041 GO_REF:0000117 MGI:2183618 RGD:7242777 RGD:727376 NCBI chr 3:59,220,203...59,225,097
Ensembl chr 3:59,218,688...59,225,249 		JBrowse link
G MAT2B methionine adenosyltransferase 2B involved_in IBA
IEA		 (PMID:21873635) GO_Central
GO_Central
UniProt
Ensembl
UniProt		 PMID:21873635 GO_REF:0000041 GO_REF:0000107 NCBI chr16:60,255,541...60,274,228
Ensembl chr16:60,255,358...60,274,135 		JBrowse link
G METTL16 methyltransferase 16, N6-methyladenosine involved_in
acts_upstream_of		 IEA
ISO		 (MGI:6199095|PMID:30197299)
(PMID:30197299)
(PMID:28525753), (PMID:30197297)		 Ensembl
Ensembl
UniProt		 PMID:28525753 PMID:30197297 PMID:30197299 GO_REF:0000107 MGI:6199095 NCBI chr12:48,491,254...48,567,253
Ensembl chr12:48,499,240...48,561,536 		JBrowse link
S-adenosylmethionine cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHCY adenosylhomocysteinase involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr17:37,726,084...37,744,378
Ensembl chr17:37,726,084...37,744,461 		JBrowse link
G AHCYL1 adenosylhomocysteinase like 1 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr 4:110,092,976...110,132,826
Ensembl chr 4:110,092,907...110,132,646 		JBrowse link
G AHCYL2 adenosylhomocysteinase like 2 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr18:19,260,226...19,441,839
Ensembl chr18:19,260,228...19,441,883 		JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO (MGI:3710265|PMID:17369066) BHF-UCL PMID:17369066 MGI:3710265 NCBI chr16:74,245,214...74,270,828
Ensembl chr16:74,245,228...74,270,783 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17484
    metabolic process 11008
      organic substance metabolic process 10576
        S-adenosylmethionine metabolic process 22
          S-adenosylmethionine biosynthetic process 5
          S-adenosylmethionine catabolic process + 0
          S-adenosylmethionine cycle + 7
Path 2
Term Annotations click to browse term
  biological_process 17484
    metabolic process 11008
      cellular metabolic process 8603
        sulfur compound metabolic process 292
          S-adenosylmethionine metabolic process 22
            S-adenosylmethionine biosynthetic process 5
            S-adenosylmethionine catabolic process + 0
            S-adenosylmethionine cycle + 7
paths to the root