Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:S-adenosylmethionine metabolic process
go back to main search page
Accession:GO:0046500 term browser browse the term
Definition:The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
Synonyms:exact_synonym: S-adenosyl methionine metabolic process;   S-adenosyl methionine metabolism;   S-adenosylmethionine metabolism;   SAM metabolic process


show annotations for term's descendants           Sort by:
S-adenosylmethionine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMD1 adenosylmethionine decarboxylase 1 ISO RGD PMID:1415709 PMID:21048303 RGD:7242909 RGD:7242912 NCBI chr12:67,432,871...67,453,791
Ensembl chr12:67,448,141...67,451,696 		JBrowse link
G BHMT betaine--homocysteine S-methyltransferase NOT|involved_in ISO (PMID:18230605) BHF-UCL PMID:18230605 NCBI chr 3:27,732,381...27,752,168
Ensembl chr 3:27,734,108...27,752,046 		JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:27,775,779...27,804,603
Ensembl chr 3:27,776,084...27,789,960 		JBrowse link
G GAMT guanidinoacetate N-methyltransferase ISO RGD PMID:15533043 RGD:1359081 NCBI chr20:57,440,698...57,442,588 JBrowse link
G GNMT glycine N-methyltransferase involved_in ISO
IEA		 RGD
Ensembl
TreeGrafter		 PMID:12054489 PMID:18501206 GO_REF:0000107 GO_REF:0000118 RGD:7242952 RGD:728472 NCBI chr12:11,500,363...11,503,075
Ensembl chr12:11,500,392...11,503,481 		JBrowse link
G HNMT histamine N-methyltransferase ISO RGD PMID:15739896 RGD:152985534 NCBI chr19:40,656,266...40,702,498
Ensembl chr19:40,655,161...40,702,218 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO RGD PMID:1201245 RGD:6893692 NCBI chr 2:84,445,526...84,457,435
Ensembl chr 2:84,380,919...84,536,818 		JBrowse link
G PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase ISO RGD PMID:8263531 RGD:729481 NCBI chr 1:40,494,441...40,539,453
Ensembl chr 1:40,494,461...40,538,937 		JBrowse link
G PEMT phosphatidylethanolamine N-methyltransferase ISO RGD PMID:8344945 RGD:729486 NCBI chr 5:41,871,685...41,960,831
Ensembl chr 5:41,872,108...41,960,828 		JBrowse link
G PRMT1 protein arginine methyltransferase 1 involved_in ISO PMID:12737817 UniProt PMID:12737817 RGD:401966876 NCBI chr 1:106,849,864...106,859,896
Ensembl chr 1:106,849,864...106,874,075 		JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APIP APAF1 interacting protein involved_in IEA UniProt GO_REF:0000104 NCBI chr18:33,012,049...33,033,453
Ensembl chr18:33,011,121...33,033,435 		JBrowse link
G ENOPH1 enolase-phosphatase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr32:6,408,778...6,451,606
Ensembl chr32:6,407,460...6,450,790 		JBrowse link
G MRI1 methylthioribose-1-phosphate isomerase 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr20:48,648,987...48,658,231
Ensembl chr20:48,653,152...48,658,160 		JBrowse link
S-adenosylmethionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAT1A methionine adenosyltransferase 1A involved_in ISO
IEA		 RGD
TreeGrafter
UniProt
InterPro		 PMID:9202427 PMID:10898761 PMID:19497982 GO_REF:0000002 GO_REF:0000041 GO_REF:0000117 GO_REF:0000118 RGD:1359039 RGD:7242770 RGD:7242777 NCBI chr 4:29,450,857...29,467,251
Ensembl chr 4:29,452,601...29,466,929 		JBrowse link
G MAT2A methionine adenosyltransferase 2A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12023972) RGD
MGI
TreeGrafter
UniProt
Ensembl
InterPro		 PMID:10898761 PMID:12023972 PMID:12029623 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 RGD:7242777 RGD:727376 NCBI chr17:39,525,635...39,532,512
Ensembl chr17:39,525,626...39,532,512 		JBrowse link
G MAT2B methionine adenosyltransferase 2B involved_in IEA UniProt
TreeGrafter
Ensembl		 GO_REF:0000041 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:47,703,991...47,726,363
Ensembl chr 4:47,709,576...47,726,360 		JBrowse link
G METTL16 methyltransferase 16, RNA N6-adenosine acts_upstream_of
involved_in		 ISO
IEA		 (PMID:28525753), (PMID:30197297)
(MGI:6199095|PMID:30197299)		 UniProt
Ensembl		 PMID:28525753 PMID:30197297 PMID:30197299 GO_REF:0000107 MGI:6199095 NCBI chr 9:46,491,503...46,566,752
Ensembl chr 9:46,496,963...46,558,313 		JBrowse link
S-adenosylmethionine cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHCY adenosylhomocysteinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr24:23,410,553...23,423,494
Ensembl chr24:23,411,140...23,419,767 		JBrowse link
G AHCYL1 adenosylhomocysteinase like 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:41,945,224...41,983,917
Ensembl chr 6:41,946,974...41,985,643 		JBrowse link
G AHCYL2 adenosylhomocysteinase like 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:7,347,173...7,509,113
Ensembl chr14:7,350,102...7,509,157 		JBrowse link
G LOC478441 adenosylhomocysteinase-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr32:1,687,020...1,707,833 JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO (MGI:3710265|PMID:17369066) BHF-UCL PMID:17369066 MGI:3710265 NCBI chr34:6,068,572...6,119,580
Ensembl chr34:6,070,046...6,098,312 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    metabolic process 10998
      organic substance metabolic process 10554
        S-adenosylmethionine metabolic process 22
          S-adenosylmethionine biosynthetic process 4
          S-adenosylmethionine catabolic process + 0
          S-adenosylmethionine cycle + 8
Path 2
Term Annotations click to browse term
  biological_process 17917
    metabolic process 10998
      cellular metabolic process 9218
        sulfur compound metabolic process 318
          S-adenosylmethionine metabolic process 22
            S-adenosylmethionine biosynthetic process 4
            S-adenosylmethionine catabolic process + 0
            S-adenosylmethionine cycle + 8
paths to the root