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ONTOLOGY REPORT - ANNOTATIONS


Term:S-adenosylmethionine metabolic process
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Accession:GO:0046500 term browser browse the term
Definition:The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
Synonyms:exact_synonym: S-adenosyl methionine metabolic process;   S-adenosyl methionine metabolism;   S-adenosylmethionine metabolism;   SAM metabolic process


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S-adenosylmethionine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 IDA RGD PMID:21048303, PMID:1415709 RGD:7242909, RGD:7242912 NCBI chr20:45,384,000...45,399,694
Ensembl chr20:45,384,000...45,399,694
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase NOT|involved_in ISO (PMID:18230605) RGD PMID:18230605 NCBI chr 2:23,236,573...23,256,158
Ensembl chr 2:23,236,575...23,256,158
JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in ISO
IEA
(PMID:18230605)
GO_REF:0000107
RGD
Ensembl
PMID:18230605 GO_REF:0000107 NCBI chr 2:23,272,320...23,289,266
Ensembl chr 2:23,272,328...23,289,266
JBrowse link
G Comt catechol-O-methyltransferase TAS RGD PMID:12584150 RGD:1359089 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Dnmt1 DNA methyltransferase 1 IDA RGD PMID:3856245 RGD:2301219 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Gamt guanidinoacetate N-methyltransferase IDA RGD PMID:15533043 RGD:1359081 NCBI chr 7:12,314,848...12,317,998
Ensembl chr 7:12,314,848...12,317,998
JBrowse link
G Gnmt glycine N-methyltransferase involved_in IMP
ISO
IBA
IDA
(MGI:3852308|PMID:15340920)
PMID:10756111
PMID:21873635
(PMID:15340920)
RGD PMID:15340920, PMID:12054489, PMID:10756111, PMID:21873635, PMID:15340920, PMID:18501206 MGI:3852308, RGD:728472, RGD:12793006, RGD:13792537, RGD:8553948, RGD:7242952 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627
JBrowse link
G Mthfr methylenetetrahydrofolate reductase IEP RGD PMID:1201245 RGD:6893692 NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 IDA RGD PMID:8263531 RGD:729481 NCBI chr 1:1,734,863...1,767,759
Ensembl chr 1:1,736,276...1,767,618
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase IDA RGD PMID:8344945 RGD:729486 NCBI chr10:46,339,821...46,404,640
Ensembl chr10:46,339,821...46,404,642
JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase TAS RGD PMID:12438084 RGD:1359087 NCBI chr10:86,340,893...86,342,501
Ensembl chr10:86,340,940...86,342,858
JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apip APAF1 interacting protein involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:92,969,128...92,998,104
Ensembl chr 3:92,969,141...92,995,483
JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:11,172,359...11,198,799
Ensembl chr14:11,172,362...11,198,194
JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr19:25,360,299...25,366,283
Ensembl chr19:25,360,164...25,366,806
JBrowse link
S-adenosylmethionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mat1a methionine adenosyltransferase 1A involved_in IDA
IEA
ISO
IBA
GO_REF:0000041
(PMID:10677294)
PMID:21873635
UniProt
RGD
PMID:10677294, PMID:9202427, PMID:21873635, PMID:10898761, PMID:19497982 GO_REF:0000041, RGD:1359039, RGD:13792537, RGD:7242777, RGD:7242770 NCBI chr16:18,690,649...18,709,135
Ensembl chr16:18,690,246...18,709,133
JBrowse link
G Mat2a methionine adenosyltransferase 2A acts_upstream_of_or_within
involved_in
TAS
ISO
IEA
IBA
IDA
(MGI:2183618|PMID:12023972)
GO_REF:0000041
PMID:21873635
(PMID:10644686), (PMID:25075345)
RGD
UniProt
PMID:10644686 PMID:12023972 PMID:25075345, PMID:11099469, PMID:21873635, PMID:10898761, PMID:12029623 GO_REF:0000041 MGI:2183618, RGD:1359040, RGD:13792537, RGD:7242777, RGD:727376 NCBI chr 4:100,297,478...100,303,047
Ensembl chr 4:100,296,075...100,303,080
JBrowse link
G Mat2b methionine adenosyltransferase 2B involved_in IBA
ISS
ISO
IEA
PMID:21873635
GO_REF:0000024
(PMID:10644686), (PMID:25075345)
GO_REF:0000041
UniProt
RGD
PMID:10644686 PMID:25075345, PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr10:25,832,096...25,848,045
Ensembl chr10:25,832,072...25,847,994
JBrowse link
G Mettl16 methyltransferase like 16 acts_upstream_of ISO (PMID:28525753), (PMID:30197297), (PMID:30197299)
(MGI:6199095|PMID:30197299)
RGD PMID:28525753 PMID:30197297 PMID:30197299 MGI:6199095 NCBI chr10:61,626,595...61,682,947
Ensembl chr10:61,626,597...61,672,136
JBrowse link
S-adenosylmethionine cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahcy adenosylhomocysteinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:150,587,833...150,603,057
Ensembl chr 3:150,587,833...150,603,082
JBrowse link
G Ahcyl1 adenosylhomocysteinase-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:210,438,884...210,474,350
Ensembl chr 2:210,438,893...210,473,761
JBrowse link
G Ahcyl2 adenosylhomocysteinase-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:57,050,241...57,199,870
Ensembl chr 4:57,050,214...57,199,900
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO (MGI:3710265|PMID:17369066) RGD PMID:17369066 MGI:3710265 NCBI chr 1:37,743,089...37,774,485
Ensembl chr 1:37,743,147...37,774,015
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19599
    metabolic process 11860
      organic substance metabolic process 11392
        S-adenosylmethionine metabolic process 22
          S-adenosylmethionine biosynthetic process 4
          S-adenosylmethionine catabolic process + 0
          S-adenosylmethionine cycle + 7
Path 2
Term Annotations click to browse term
  biological_process 19599
    metabolic process 11860
      cellular metabolic process 10814
        sulfur compound metabolic process 324
          S-adenosylmethionine metabolic process 22
            S-adenosylmethionine biosynthetic process 4
            S-adenosylmethionine catabolic process + 0
            S-adenosylmethionine cycle + 7
paths to the root