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ONTOLOGY REPORT - ANNOTATIONS

Term:S-adenosylmethionine metabolic process
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Accession:GO:0046500 term browser browse the term
Definition:The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
Synonyms:exact_synonym: S-adenosyl methionine metabolic process;   S-adenosyl methionine metabolism;   S-adenosylmethionine metabolism;   SAM metabolic process


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S-adenosylmethionine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amd1 adenosylmethionine decarboxylase 1 IDA RGD PMID:21048303 PMID:1415709 RGD:7242909, RGD:7242912 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase NOT|involved_in ISO (PMID:18230605) RGD PMID:18230605 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18230605)		 Ensembl
RGD		 PMID:18230605 GO_REF:0000107 NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475 		JBrowse link
G Comt catechol-O-methyltransferase TAS RGD PMID:12584150 RGD:1359089 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Dnmt1 DNA methyltransferase 1 IDA RGD PMID:3856245 RGD:2301219 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Gamt guanidinoacetate N-methyltransferase IDA RGD PMID:15533043 RGD:1359081 NCBI chr 7:9,448,590...9,451,778
Ensembl chr 7:9,448,628...9,451,778 		JBrowse link
G Gnmt glycine N-methyltransferase involved_in IMP
IBA
ISO
IEA
IDA		 PMID:21873635
PMID:10756111
(MGI:3852308|PMID:15340920)
GO_REF:0000107
(PMID:15340920)		 RGD
Ensembl		 PMID:15340920 PMID:12054489 PMID:18501206 PMID:21873635 PMID:10756111 More... GO_REF:0000107 MGI:3852308, RGD:728472, RGD:7242952, RGD:13792537, RGD:12793006, RGD:8553948 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434 		JBrowse link
G Hnmt histamine N-methyltransferase IDA RGD PMID:15739896 RGD:152985534 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase IEP RGD PMID:1201245 RGD:6893692 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 IDA RGD PMID:8263531 RGD:729481 NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201 		JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase IDA RGD PMID:8344945 RGD:729486 NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase TAS RGD PMID:12438084 RGD:1359087 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
L-methionine salvage from S-adenosylmethionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apip APAF1 interacting protein involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 3:89,431,973...89,457,999
Ensembl chr 3:89,432,037...89,458,340 		JBrowse link
G Enoph1 enolase-phosphatase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:9,531,336...9,557,797
Ensembl chr14:9,531,339...9,569,273 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr19:23,907,335...23,913,320
Ensembl chr19:23,907,335...23,913,320 		JBrowse link
S-adenosylmethionine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mat1a methionine adenosyltransferase 1A involved_in IDA
IBA
ISO
IEA		 PMID:21873635
(PMID:10677294), (PMID:25075345)
GO_REF:0000041		 RGD
UniProt		 PMID:10677294 PMID:25075345 PMID:9202427 PMID:21873635 PMID:19497982 More... GO_REF:0000041, RGD:1359039, RGD:13792537, RGD:7242770, RGD:7242777 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274 		JBrowse link
G Mat2a methionine adenosyltransferase 2A involved_in
acts_upstream_of_or_within		 TAS
IBA
ISO
IEA
IDA		 PMID:21873635
(PMID:10644686), (PMID:25075345)
(MGI:2183618|PMID:12023972)
GO_REF:0000041		 RGD
UniProt		 PMID:10644686 PMID:12023972 PMID:25075345 PMID:11099469 PMID:21873635 More... GO_REF:0000041 MGI:2183618, RGD:1359040, RGD:13792537, RGD:7242777, RGD:727376 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493 		JBrowse link
G Mat2b methionine adenosyltransferase 2B involved_in ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:10644686), (PMID:25075345)
GO_REF:0000041
PMID:21873635		 UniProt
RGD		 PMID:10644686 PMID:25075345 PMID:21873635 GO_REF:0000024 GO_REF:0000041, RGD:13792537 NCBI chr10:25,106,928...25,122,982
Ensembl chr10:25,106,930...25,122,777 		JBrowse link
G Mettl16 methyltransferase 16, N6-methyladenosine acts_upstream_of ISO (MGI:6199095|PMID:30197299)
(PMID:28525753), (PMID:30197297), (PMID:30197299)		 RGD PMID:28525753 PMID:30197297 PMID:30197299 MGI:6199095 NCBI chr10:59,640,915...59,697,291
Ensembl chr10:59,640,972...59,687,061 		JBrowse link
G RGD1560523 similar to S-adenosylmethionine synthetase gamma form (Methionine adenosyltransferase) involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr13:26,088,997...26,090,862
Ensembl chr13:26,089,606...26,090,793 		JBrowse link
S-adenosylmethionine cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahcy adenosylhomocysteinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393 		JBrowse link
G Ahcyl1 adenosylhomocysteinase-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:195,294,149...195,328,586
Ensembl chr 2:195,294,153...195,345,815 		JBrowse link
G Ahcyl2 adenosylhomocysteinase-like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:58,381,290...58,531,061
Ensembl chr 4:58,381,218...58,531,060 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO (MGI:3710265|PMID:17369066) RGD PMID:17369066 MGI:3710265 NCBI chr 1:34,866,991...34,899,425
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19746
    metabolic process 12044
      organic substance metabolic process 11597
        S-adenosylmethionine metabolic process 24
          S-adenosylmethionine biosynthetic process 5
          S-adenosylmethionine catabolic process + 0
          S-adenosylmethionine cycle + 7
Path 2
Term Annotations click to browse term
  biological_process 19746
    metabolic process 12044
      cellular metabolic process 9531
        sulfur compound metabolic process 303
          S-adenosylmethionine metabolic process 24
            S-adenosylmethionine biosynthetic process 5
            S-adenosylmethionine catabolic process + 0
            S-adenosylmethionine cycle + 7
paths to the root