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ONTOLOGY REPORT - ANNOTATIONS


Term:S-adenosylhomocysteine metabolic process
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Accession:GO:0046498 term browser browse the term
Definition:The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine.
Synonyms:exact_synonym: S-adenosylhomocysteine metabolism


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S-adenosylhomocysteine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase TAS RGD PMID:12584150 RGD:1359089 NCBI chr11:82,568,052...82,587,642 JBrowse link
G Gamt guanidinoacetate N-methyltransferase IDA RGD PMID:15533043 RGD:1359081 NCBI chr 7:9,448,590...9,451,778 JBrowse link
G Gnmt glycine N-methyltransferase involved_in IDA
IBA
IMP
PMID:21873635
PMID:10756111
RGD
GO_Central
CAFA
PMID:15347642, PMID:21873635, PMID:10756111 RGD:1359070, RGD:13792537, RGD:12793006 NCBI chr 9:14,254,675...14,258,028 JBrowse link
G Icmt isoprenylcysteine carboxyl methyltransferase IMP RGD PMID:9192075 RGD:2289655 NCBI chr 5:162,804,368...162,811,129 JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 IDA RGD PMID:8263531 RGD:729481 NCBI chr 1:2,111,756...2,160,354 JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase IDA RGD PMID:8344945 RGD:729486 NCBI chr10:44,775,910...44,849,990 JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase TAS RGD PMID:12438084 RGD:1359087 NCBI chr10:83,383,019...83,386,557 JBrowse link
S-adenosylhomocysteine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahcy adenosylhomocysteinase acts_upstream_of_or_within IDA
ISO
(MGI:2183618|PMID:12023972) RGD PMID:12023972, PMID:11741948 MGI:2183618, RGD:730275 NCBI chr 3:143,569,134...143,584,359 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    metabolic process 11795
      cellular metabolic process 10753
        cellular modified amino acid metabolic process 202
          S-adenosylhomocysteine metabolic process 8
            S-adenosylhomocysteine catabolic process 1
Path 2
Term Annotations click to browse term
  biological_process 19492
    cellular process 18342
      cellular metabolic process 10753
        cellular aromatic compound metabolic process 5636
          nucleobase-containing compound metabolic process 5419
            nucleobase-containing small molecule metabolic process 577
              nucleoside metabolic process 64
                purine nucleoside metabolic process 36
                  purine ribonucleoside metabolic process 30
                    S-adenosylhomocysteine metabolic process 8
                      S-adenosylhomocysteine catabolic process 1
paths to the root