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ONTOLOGY REPORT - ANNOTATIONS

Term:nicotinamide nucleotide metabolic process
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Accession:GO:0046496 term browser browse the term
Definition:The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.
Synonyms:exact_synonym: nicotinamide nucleotide metabolism


show annotations for term's descendants           Sort by:
 
nicotinamide nucleotide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NAXD NAD(P)HX dehydratase involved_in IEA UniProt
UniProt		 GO_REF:0000104 NCBI chr13:110,615,460...110,639,996
Ensembl chr13:110,615,545...110,639,996 		JBrowse link
G NAXE NAD(P)HX epimerase involved_in IMP (PMID:27616477) UniProt
UniProt		 PMID:27616477 NCBI chr 1:156,591,776...156,594,299
Ensembl chr 1:156,591,756...156,609,507 		JBrowse link
'de novo' NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NADSYN1 NAD synthetase 1 involved_in IMP (PMID:31883644) UniProt
UniProt		 PMID:31883644 NCBI chr11:71,453,203...71,501,816
Ensembl chr11:71,453,109...71,524,107 		JBrowse link
'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFMID arylformamidase involved_in IEA UniProt
UniProt		 GO_REF:0000104 NCBI chr17:78,187,362...78,207,702
Ensembl chr17:78,187,358...78,207,702 		JBrowse link
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase involved_in IBA
IEA		 (PMID:21873635) GO_Central
UniProt
GO_Central		 PMID:21873635 GO_REF:0000104 NCBI chr 2:42,767,089...42,792,583
Ensembl chr 2:42,767,089...42,792,593 		JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790 		JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr 8:39,934,651...40,016,392
Ensembl chr 8:39,934,614...40,016,392 		JBrowse link
G KMO kynurenine 3-monooxygenase involved_in IEA UniProt
UniProt		 GO_REF:0000104 NCBI chr 1:241,532,378...241,595,642
Ensembl chr 1:241,532,134...241,595,642 		JBrowse link
G KYNU kynureninase involved_in IEA UniProt
UniProt		 GO_REF:0000104 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833 		JBrowse link
NAD biosynthesis via nicotinamide riboside salvage pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NAMPT nicotinamide phosphoribosyltransferase involved_in TAS Reactome
Reactome		 Reactome:R-HSA-197264 NCBI chr 7:106,248,298...106,285,888
Ensembl chr 7:106,248,298...106,285,966 		JBrowse link
G NAXD NAD(P)HX dehydratase involved_in TAS Reactome
Reactome		 Reactome:R-HSA-197264 NCBI chr13:110,615,460...110,639,996
Ensembl chr13:110,615,545...110,639,996 		JBrowse link
G NNMT nicotinamide N-methyltransferase involved_in TAS Reactome
Reactome		 Reactome:R-HSA-197264 NCBI chr11:114,257,806...114,313,536
Ensembl chr11:114,257,787...114,313,536 		JBrowse link
G NUDT12 nudix hydrolase 12 involved_in TAS Reactome
Reactome		 Reactome:R-HSA-197264 NCBI chr 5:103,548,855...103,562,789
Ensembl chr 5:103,548,855...103,562,790 		JBrowse link
G PARP10 poly(ADP-ribose) polymerase family member 10 involved_in TAS Reactome
Reactome		 Reactome:R-HSA-197264 NCBI chr 8:143,977,158...144,012,764
Ensembl chr 8:143,977,153...144,012,772 		JBrowse link
G PARP16 poly(ADP-ribose) polymerase family member 16 involved_in TAS Reactome
Reactome		 Reactome:R-HSA-197264 NCBI chr15:65,230,917...65,286,883
Ensembl chr15:65,234,460...65,300,618 		JBrowse link
G PARP9 poly(ADP-ribose) polymerase family member 9 involved_in TAS Reactome
Reactome		 Reactome:R-HSA-197264 NCBI chr 3:122,527,924...122,564,784
Ensembl chr 3:122,527,924...122,564,577 		JBrowse link
G PTGIS prostaglandin I2 synthase involved_in TAS Reactome
Reactome		 Reactome:R-HSA-197264 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137 		JBrowse link
G SLC22A13 solute carrier family 22 member 13 involved_in TAS Reactome
Reactome		 Reactome:R-HSA-197264 NCBI chr 3:38,265,812...38,278,757
Ensembl chr 3:38,265,812...38,278,757 		JBrowse link
G SLC5A8 solute carrier family 5 member 8 involved_in TAS Reactome
Reactome		 Reactome:R-HSA-197264 NCBI chr12:101,155,493...101,210,238
Ensembl chr12:101,155,493...101,210,238 		JBrowse link
NAD biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASPDH aspartate dehydrogenase domain containing involved_in IEA UniProt
InterPro
InterPro		 GO_REF:0000002 GO_REF:0000041 NCBI chr19:50,511,603...50,515,101
Ensembl chr19:50,511,600...50,514,690 		JBrowse link
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase involved_in IMP
IEA		 (PMID:28792876) UniProt
UniProt		 PMID:28792876 GO_REF:0000041 NCBI chr 2:42,767,089...42,792,583
Ensembl chr 2:42,767,089...42,792,593 		JBrowse link
G KMO kynurenine 3-monooxygenase involved_in IEA UniProt GO_REF:0000041 NCBI chr 1:241,532,378...241,595,642
Ensembl chr 1:241,532,134...241,595,642 		JBrowse link
G KYNU kynureninase involved_in IMP
IEA		 (PMID:28792876) UniProt
UniProt
InterPro
InterPro		 PMID:28792876 GO_REF:0000002 GO_REF:0000041 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833 		JBrowse link
G NADSYN1 NAD synthetase 1 involved_in IBA
IEA		 (PMID:21873635) GO_Central
InterPro
UniProt
GO_Central
UniProt
InterPro		 PMID:21873635 GO_REF:0000002 GO_REF:0000041 NCBI chr11:71,453,203...71,501,816
Ensembl chr11:71,453,109...71,524,107 		JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:21873635)
(MGI:3522067|PMID:15381699)		 UniProt
GO_Central
InterPro
UniProt
Ensembl
GO_Central
MGI		 PMID:15381699 PMID:21873635 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 MGI:3522067 NCBI chr 7:106,248,298...106,285,888
Ensembl chr 7:106,248,298...106,285,966 		JBrowse link
G NAPRT nicotinate phosphoribosyltransferase involved_in IEA
ISO		 UniProt
UniProt
InterPro
RGD		 PMID:8694849 GO_REF:0000002 GO_REF:0000041 GO_REF:0000104 RGD:2289495 NCBI chr 8:143,572,874...143,578,330
Ensembl chr 8:143,574,785...143,578,649 		JBrowse link
G NMNAT1 nicotinamide nucleotide adenylyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:21873635)
(MGI:3522067|PMID:15381699), (MGI:3654729|PMID:16914673)		 UniProt
UniProt
Ensembl
InterPro
GO_Central
MGI
GO_Central		 PMID:15381699 PMID:16914673 PMID:21873635 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 MGI:3522067 MGI:3654729 NCBI chr 1:9,942,923...9,996,892
Ensembl chr 1:9,943,428...9,985,501 		JBrowse link
G NMNAT2 nicotinamide nucleotide adenylyltransferase 2 involved_in IEA
IBA
ISO		 (PMID:21873635) UniProt
UniProt
GO_Central
InterPro
RGD
GO_Central		 PMID:21873635 PMID:22449973 GO_REF:0000002 GO_REF:0000041 RGD:13782043 NCBI chr 1:183,248,237...183,418,380
Ensembl chr 1:183,248,237...183,418,380 		JBrowse link
G NMNAT3 nicotinamide nucleotide adenylyltransferase 3 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:21873635)
(MGI:3654729|PMID:16914673)		 UniProt
InterPro
Ensembl
GO_Central
UniProt
MGI
GO_Central		 PMID:16914673 PMID:21873635 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 MGI:3654729 NCBI chr 3:139,560,180...139,678,050
Ensembl chr 3:139,560,180...139,678,017 		JBrowse link
G NMRK1 nicotinamide riboside kinase 1 involved_in IEA UniProt
UniProt		 GO_REF:0000041 NCBI chr 9:75,060,577...75,088,155
Ensembl chr 9:75,060,573...75,088,217 		JBrowse link
G NMRK2 nicotinamide riboside kinase 2 involved_in IEA UniProt
UniProt		 GO_REF:0000041 NCBI chr19:3,933,069...3,942,416
Ensembl chr19:3,933,069...3,942,416 		JBrowse link
G QPRT quinolinate phosphoribosyltransferase involved_in IBA
IEA
ISO		 (PMID:21873635) GO_Central
InterPro
UniProt
GO_Central
RGD
UniProt		 PMID:8694849 PMID:21873635 GO_REF:0000002 GO_REF:0000041 RGD:2289495 NCBI chr16:29,679,008...29,698,699
Ensembl chr16:29,663,279...29,698,699 		JBrowse link
NAD catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT12 nudix hydrolase 12 involved_in
acts_upstream_of_or_within		 IBA
IDA		 (PMID:21873635)
(PMID:12790796)		 GO_Central
UniProt
MGI
GO_Central
MGI		 PMID:12790796 PMID:21873635 NCBI chr 5:103,548,855...103,562,789
Ensembl chr 5:103,548,855...103,562,790 		JBrowse link
G NUDT17 nudix hydrolase 17 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr 1:145,845,630...145,848,954
Ensembl chr 1:145,845,630...145,848,954 		JBrowse link
G SARM1 sterile alpha and TIR motif containing 1 involved_in IDA
IEA		 (PMID:25908823), (PMID:27671644), (PMID:28334607), (PMID:31128467), (PMID:31439792), (PMID:31439793), (PMID:32049506), (PMID:32828421), (PMID:33053563) UniProt
UniProt
Ensembl		 PMID:25908823 PMID:27671644 PMID:28334607 PMID:31128467 PMID:31439792 More... GO_REF:0000107 GO_REF:0000117 NCBI chr17:28,371,694...28,404,049
Ensembl chr17:28,364,356...28,404,049 		JBrowse link
G TIGD7 tigger transposable element derived 7 involved_in ISO (MGI:5426136|PMID:11011142) UniProt PMID:11011142 MGI:5426136 NCBI chr16:3,298,808...3,305,430
Ensembl chr16:3,298,808...3,305,729 		JBrowse link
NAD salvage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NAPRT nicotinate phosphoribosyltransferase involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr 8:143,572,874...143,578,330
Ensembl chr 8:143,574,785...143,578,649 		JBrowse link
NADP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6PD glucose-6-phosphate dehydrogenase acts_upstream_of_or_within ISO (MGI:1097071|PMID:9330624), (MGI:1202104|PMID:9539108), (MGI:1261671|PMID:9627357), (MGI:54902|PMID:7439685), (MGI:87492|PMID:9169132)
(MGI:3522057|PMID:15271799)
(MGI:1349468|PMID:3377761), (MGI:2387959|PMID:10627286), (MGI:3607389|PMID:14757696), (MGI:3694178|PMID:15998684), (MGI:49164|PMID:1953691), (MGI:85983|PMID:9067418)		 MGI PMID:1953691 PMID:3377761 PMID:7439685 PMID:9067418 PMID:9169132 More... MGI:1097071 MGI:1202104 MGI:1261671 MGI:1349468 MGI:2387959 MGI:3522057 MGI:3607389 MGI:3694178 MGI:49164 MGI:54902 MGI:85983 MGI:87492 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 ISO RGD PMID:21641335 RGD:11522736 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,477 		JBrowse link
G NADK NAD kinase involved_in IBA
IEA
ISO		 (PMID:21873635) GO_Central
GO_Central
InterPro
RGD
InterPro		 PMID:21873635 PMID:22550069 GO_REF:0000002 RGD:13703105 NCBI chr 1:1,751,232...1,780,514
Ensembl chr 1:1,751,232...1,780,457 		JBrowse link
G NADK2 NAD kinase 2, mitochondrial involved_in IEA InterPro
InterPro
UniProt
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr 5:36,192,589...36,242,279
Ensembl chr 5:36,192,589...36,242,279 		JBrowse link
NADP catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT12 nudix hydrolase 12 involved_in
acts_upstream_of_or_within		 IBA
IDA		 (PMID:21873635)
(PMID:12790796)		 GO_Central
GO_Central
MGI
UniProt
MGI		 PMID:12790796 PMID:21873635 NCBI chr 5:103,548,855...103,562,789
Ensembl chr 5:103,548,855...103,562,790 		JBrowse link
G NUDT13 nudix hydrolase 13 involved_in ISS
IEA		 UniProt
Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:73,110,455...73,131,823
Ensembl chr10:73,110,375...73,131,828 		JBrowse link
G NUDT17 nudix hydrolase 17 involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr 1:145,845,630...145,848,954
Ensembl chr 1:145,845,630...145,848,954 		JBrowse link
regulation of 'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACMSD aminocarboxymuconate semialdehyde decarboxylase involved_in TAS (PMID:12140278), (PMID:19843166) ParkinsonsUK-UCL
ParkinsonsUK-UCL		 PMID:12140278 PMID:19843166 NCBI chr 2:134,838,616...134,902,034
Ensembl chr 2:134,838,616...134,902,034 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19656
    metabolic process 13108
      cellular metabolic process 10997
        heterocycle metabolic process 6769
          pyridine-containing compound metabolic process 44
            pyridine nucleotide metabolic process 35
              nicotinamide nucleotide metabolic process 35
                NAD catabolic process 4
                NADP catabolic process 3
                nicotinamide nucleotide biosynthetic process + 30
Path 2
Term Annotations click to browse term
  biological_process 19656
    metabolic process 13108
      cellular metabolic process 10997
        heterocycle metabolic process 6769
          nucleobase-containing compound metabolic process 6584
            nucleobase-containing small molecule metabolic process 705
              nucleoside phosphate metabolic process 628
                nucleotide metabolic process 620
                  pyridine nucleotide metabolic process 35
                    nicotinamide nucleotide metabolic process 35
                      NAD catabolic process 4
                      NADP catabolic process 3
                      nicotinamide nucleotide biosynthetic process + 30
paths to the root