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ONTOLOGY REPORT - ANNOTATIONS


Term:phosphatidylglycerol metabolic process
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Accession:GO:0046471 term browser browse the term
Definition:The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes.
Synonyms:exact_synonym: phosphatidylglycerol metabolism



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phosphatidylglycerol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA3 ATP binding cassette subfamily A member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,679,312...38,712,868
Ensembl chr 6:38,679,324...38,712,648
JBrowse link
G PLA2G10 phospholipase A2 group X involved_in IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 6:28,573,239...28,591,714
Ensembl chr 6:28,574,387...28,591,703
JBrowse link
G PLA2G15 phospholipase A2 group XV involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 5:81,269,914...81,280,700
Ensembl chr 5:81,269,920...81,280,700
JBrowse link
G PLA2G1B phospholipase A2 group IB involved_in ISS
IBA
IEA
UniProt
GO_Central
Ensembl
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr26:16,248,417...16,257,163
Ensembl chr26:16,248,409...16,257,178
JBrowse link
G PLA2G2C phospholipase A2 group IIC involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:78,609,852...78,700,940 JBrowse link
G PLA2G2D phospholipase A2 group IID involved_in IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 2:78,739,826...78,745,839
Ensembl chr 2:78,739,769...78,745,920
JBrowse link
G PLA2G2E phospholipase A2 group IIE involved_in IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 2:78,834,820...78,838,058
Ensembl chr 2:78,831,309...78,841,821
JBrowse link
G PLA2G2F phospholipase A2 group IIF involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:78,714,251...78,724,257
Ensembl chr 2:78,716,228...78,723,984
JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:24,127,074...24,132,508
Ensembl chr26:24,128,005...24,132,508
JBrowse link
G PLA2G5 phospholipase A2 group V involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:78,762,851...78,781,642
Ensembl chr 2:78,762,852...78,781,983
JBrowse link
cardiolipin acyl-chain remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:20,307,207...20,355,659
Ensembl chr17:20,307,226...20,355,508
JBrowse link
G PLA2G6 phospholipase A2 group VI involved_in IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr10:26,499,033...26,559,533
Ensembl chr10:26,509,695...26,634,087
JBrowse link
G TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:122,111,608...122,125,714
Ensembl chr  X:122,111,434...122,125,506
JBrowse link
G THEM5 thioesterase superfamily member 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:60,857,348...60,865,789
Ensembl chr17:60,857,350...60,865,579
JBrowse link
cardiolipin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRLS1 cardiolipin synthase 1 involved_in ISO (PMID:16678169), (PMID:16716149)
(PMID:35147173)
UniProt PMID:16678169 PMID:16716149 PMID:35147173 NCBI chr24:15,814,111...15,837,485
Ensembl chr24:15,814,770...15,893,458
JBrowse link
G PGS1 phosphatidylglycerophosphate synthase 1 involved_in IEA
IBA
InterPro
GO_Central
GO_REF:0000002 GO_REF:0000033 NCBI chr 9:2,808,169...2,845,308
Ensembl chr 9:2,808,338...2,845,722
JBrowse link
G PTPMT1 protein tyrosine phosphatase mitochondrial 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,081,414...42,087,435
Ensembl chr18:42,081,262...42,087,423
JBrowse link
G TAMM41 TAM41 mitochondrial translocator assembly and maintenance homolog involved_in IEA
IBA
UniProt
GO_Central
InterPro
GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr20:6,650,347...6,703,407
Ensembl chr20:6,653,026...6,709,922
JBrowse link
cardiolipin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MECP2 methyl-CpG binding protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17237885) Ensembl
MGI
PMID:17237885 GO_REF:0000107 NCBI chr  X:121,866,721...121,876,088
Ensembl chr  X:121,873,218...121,932,994
JBrowse link
G MECP2 methyl-CpG binding protein 2 involved_in IEA Ensembl GO_REF:0000107
G PNPLA8 patatin like phospholipase domain containing 8 involved_in ISO (PMID:28442572) UniProt PMID:28442572 NCBI chr18:12,134,921...12,181,496
Ensembl chr18:12,141,830...12,179,974
JBrowse link
G TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase involved_in ISO (PMID:21068380), (PMID:26114544) UniProt PMID:21068380 PMID:26114544 NCBI chr  X:122,111,608...122,125,714
Ensembl chr  X:122,111,434...122,125,506
JBrowse link
phosphatidylglycerol acyl-chain remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G2F phospholipase A2 group IIF involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:78,714,251...78,724,257
Ensembl chr 2:78,716,228...78,723,984
JBrowse link
G SERAC1 serine active site containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:47,599,802...47,651,034
Ensembl chr 1:47,578,472...47,669,494
JBrowse link
phosphatidylglycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:23,261,673...23,323,985
Ensembl chr28:23,258,428...23,298,017
JBrowse link
G PGS1 phosphatidylglycerophosphate synthase 1 involved_in IEA UniProt GO_REF:0000041 NCBI chr 9:2,808,169...2,845,308
Ensembl chr 9:2,808,338...2,845,722
JBrowse link
phosphatidylglycerol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLA2G4A phospholipase A2 group IVA involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:19,804,412...19,955,215
Ensembl chr 7:19,832,664...19,966,936
JBrowse link
G PLB1 phospholipase B1 involved_in ISO PMID:9442064 UniProt PMID:9442064 RGD:30309923 NCBI chr17:22,420,679...22,558,318
Ensembl chr17:22,440,651...22,557,737
JBrowse link
positive regulation of cardiolipin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPATA18 spermatogenesis associated 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:44,996,770...45,034,327
Ensembl chr13:44,996,517...45,033,626
JBrowse link
G TAFAZZIN tafazzin, phospholipid-lysophospholipid transacylase ISO RGD PMID:20348225 RGD:13432160 NCBI chr  X:122,111,608...122,125,714
Ensembl chr  X:122,111,434...122,125,506
JBrowse link
regulation of cardiolipin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJC19 DnaJ heat shock protein family (Hsp40) member C19 involved_in ISO (PMID:24856930) UniProt PMID:24856930 NCBI chr34:14,199,507...14,204,736
Ensembl chr34:14,199,675...14,204,687
JBrowse link
G PHB2 prohibitin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:38,075,769...38,080,440
Ensembl chr27:38,075,652...38,080,109
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22121
    cellular process 21652
      metabolic process 15394
        primary metabolic process 13985
          lipid metabolic process 1351
            phospholipid metabolic process 366
              glycerophospholipid metabolic process 276
                phosphatidylglycerol metabolic process 28
                  cardiolipin metabolic process + 14
                  phosphatidylglycerol acyl-chain remodeling 2
                  phosphatidylglycerol biosynthetic process + 5
                  phosphatidylglycerol catabolic process 2
paths to the root