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ONTOLOGY REPORT - ANNOTATIONS

Term:phosphatidylglycerol metabolic process
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Accession:GO:0046471 term browser browse the term
Definition:The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes.
Synonyms:exact_synonym: phosphatidylglycerol metabolism


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phosphatidylglycerol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP binding cassette subfamily A member 3 involved_in ISO (PMID:17142808), (PMID:17267394) RGD PMID:17142808 PMID:17267394 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745 		JBrowse link
G Oc90 otoconin 90 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:97,635,890...97,669,303
Ensembl chr 7:97,635,890...97,669,416 		JBrowse link
G Pla2g10 phospholipase A2, group X involved_in IEA
ISO
ISS
IBA		 GO_REF:0000107
(PMID:12359733)
GO_REF:0000024
GO_REF:0000033		 Ensembl
RGD
UniProt
GO_Central		 PMID:12359733 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000 		JBrowse link
G Pla2g15 phospholipase A2, group XV involved_in ISO
ISS		 (PMID:29724779)
GO_REF:0000024		 RGD
UniProt		 PMID:29724779 GO_REF:0000024 NCBI chr19:34,050,685...34,068,070
Ensembl chr19:34,050,694...34,068,063 		JBrowse link
G Pla2g1b phospholipase A2 group IB involved_in ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:1420353)
GO_REF:0000107
GO_REF:0000033		 UniProt
RGD
Ensembl
GO_Central		 PMID:1420353 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226 		JBrowse link
G Pla2g2a phospholipase A2 group IIA involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Pla2g2c phospholipase A2, group IIC involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:150,959,365...150,981,388
Ensembl chr 5:150,959,182...150,981,377 		JBrowse link
G Pla2g2d phospholipase A2, group IID involved_in ISO
IBA		 (PMID:10531313)
GO_REF:0000033		 RGD
GO_Central		 PMID:10531313 GO_REF:0000033 NCBI chr 5:151,016,010...151,022,531
Ensembl chr 5:151,018,870...151,022,525 		JBrowse link
G Pla2g2e phospholipase A2, group IIE involved_in ISO (PMID:10531313) RGD PMID:10531313 NCBI chr 5:151,121,363...151,127,147
Ensembl chr 5:151,121,439...151,126,821 		JBrowse link
G Pla2g2f phospholipase A2, group IIF involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:150,986,788...150,993,175
Ensembl chr 5:150,986,788...150,993,175 		JBrowse link
G Pla2g3 phospholipase A2, group III involved_in ISO (PMID:28947740) RGD PMID:28947740 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913 		JBrowse link
G Pla2g5 phospholipase A2, group V involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658 		JBrowse link
cardiolipin acyl-chain remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:23152787)		 UniProt
RGD		 PMID:23152787 GO_REF:0000024 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869 		JBrowse link
G Pla2g5 phospholipase A2, group V involved_in ISO
IEA
ISS		 (PMID:23533611)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:23533611 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658 		JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in ISO
IBA
IEA
IDA
ISS		 (PMID:23533611)
GO_REF:0000033
GO_REF:0000107
PMID:24648512
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:23533611 PMID:24648512 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:25671395 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114 		JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:152,065,539...152,076,178
Ensembl chr  X:152,065,609...152,074,001 		JBrowse link
G Them5 thioesterase superfamily member 5 involved_in IBA
ISO		 GO_REF:0000033
(PMID:22586271)		 GO_Central
RGD		 PMID:22586271 GO_REF:0000033 NCBI chr 2:181,980,783...181,986,002
Ensembl chr 2:181,980,783...181,986,002 		JBrowse link
cardiolipin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crls1 cardiolipin synthase 1 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:16678169)		 UniProt
GO_Central
RGD		 PMID:16678169 GO_REF:0000024 GO_REF:0000033 NCBI chr 3:120,119,822...120,138,674
Ensembl chr 3:120,119,852...120,138,655 		JBrowse link
G Pgs1 phosphatidylglycerophosphate synthase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:103,214,635...103,250,254
Ensembl chr10:103,214,646...103,250,254 		JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in ISO
IEA		 (PMID:19164547)
GO_REF:0000107		 RGD
Ensembl		 PMID:19164547 GO_REF:0000107 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114 		JBrowse link
G Plscr3 phospholipid scramblase 3 involved_in ISO
IEA
ISS		 (PMID:16939411)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:16939411 GO_REF:0000024 GO_REF:0000107 NCBI chr10:54,566,556...54,573,240
Ensembl chr10:54,566,873...54,578,709 		JBrowse link
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21641550)		 UniProt
RGD		 PMID:21641550 GO_REF:0000024 NCBI chr 3:76,889,922...76,899,427
Ensembl chr 3:76,889,922...76,899,427 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in ISO
IEA		 (PMID:19523918)
GO_REF:0000107		 RGD
Ensembl		 PMID:19523918 GO_REF:0000107 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063 		JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase involved_in ISO (PMID:11118295), (PMID:16873891), (PMID:17043667), (PMID:19164547) RGD PMID:11118295 PMID:16873891 PMID:17043667 PMID:19164547 NCBI chr  X:152,065,539...152,076,178
Ensembl chr  X:152,065,609...152,074,001 		JBrowse link
G Tamm41 TAM41 mitochondrial translocator assembly and maintenance homolog involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:148,070,388...148,103,728
Ensembl chr 4:148,018,463...148,103,694 		JBrowse link
cardiolipin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mecp2 methyl CpG binding protein 2 acts_upstream_of_or_within ISO MGI:2137311 (PMID:17237885) RGD PMID:17237885 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
G Pnpla8 patatin-like phospholipase domain containing 8 involved_in ISS
ISO		 GO_REF:0000024
(PMID:28442572)		 UniProt
RGD		 PMID:28442572 GO_REF:0000024 NCBI chr 6:61,329,810...61,391,736
Ensembl chr 6:61,329,810...61,391,734 		JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase involved_in ISO (PMID:26908608), (PMID:33096711)
(PMID:21068380), (PMID:26114544)
(PMID:19700766)		 RGD PMID:19700766 PMID:21068380 PMID:26114544 PMID:26908608 PMID:33096711 NCBI chr  X:152,065,539...152,076,178
Ensembl chr  X:152,065,609...152,074,001 		JBrowse link
phosphatidylglycerol acyl-chain remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g2f phospholipase A2, group IIF involved_in ISO (PMID:11112443) RGD PMID:11112443 NCBI chr 5:150,986,788...150,993,175
Ensembl chr 5:150,986,788...150,993,175 		JBrowse link
G Serac1 serine active site containing 1 involved_in ISO (PMID:22683713) RGD PMID:22683713 NCBI chr 1:46,620,741...46,656,801
Ensembl chr 1:46,620,498...46,656,727 		JBrowse link
phosphatidylglycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial involved_in ISO
ISS
IEA		 (PMID:19075029)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:19075029 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in ISO (PMID:19523918) RGD PMID:19523918 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063 		JBrowse link
phosphatidylglycerol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g4a phospholipase A2 group 4A involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:9425121)		 UniProt
Ensembl
RGD		 PMID:9425121 GO_REF:0000024 GO_REF:0000107 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Plb1 phospholipase B1 involved_in IDA PMID:9442064 UniProt PMID:9442064 RGD:30309923 NCBI chr 6:24,087,051...24,227,167
Ensembl chr 6:24,089,214...24,210,117 		JBrowse link
positive regulation of cardiolipin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spata18 spermatogenesis associated 18 involved_in IEA
ISO		 GO_REF:0000107
(PMID:38322995)		 Ensembl
RGD		 PMID:38322995 GO_REF:0000107 NCBI chr14:34,531,931...34,558,671
Ensembl chr14:34,531,061...34,558,687 		JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase IMP RGD PMID:20348225 RGD:13432160 NCBI chr  X:152,065,539...152,076,178
Ensembl chr  X:152,065,609...152,074,001 		JBrowse link
regulation of cardiolipin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 involved_in ISO (PMID:24856930) RGD PMID:24856930 NCBI chr 2:116,923,272...116,945,312
Ensembl chr 2:116,923,272...116,945,264 		JBrowse link
G Phb2 prohibitin 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24856930)		 UniProt
Ensembl
RGD		 PMID:24856930 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    cellular process 19154
      metabolic process 11953
        primary metabolic process 10582
          lipid metabolic process 1452
            phospholipid metabolic process 372
              glycerophospholipid metabolic process 276
                phosphatidylglycerol metabolic process 31
                  cardiolipin metabolic process + 16
                  phosphatidylglycerol acyl-chain remodeling 2
                  phosphatidylglycerol biosynthetic process + 9
                  phosphatidylglycerol catabolic process 2
paths to the root