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ONTOLOGY REPORT - ANNOTATIONS

Term:phosphatidylglycerol metabolic process
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Accession:GO:0046471 term browser browse the term
Definition:The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes.
Synonyms:exact_synonym: phosphatidylglycerol metabolism


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phosphatidylglycerol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP binding cassette subfamily A member 3 involved_in ISO (MGI:3706225|PMID:17142808), (MGI:3709444|PMID:17267394) RGD PMID:17142808 PMID:17267394 MGI:3706225 MGI:3709444 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745 		JBrowse link
G Pla2g10 phospholipase A2, group X involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:12359733)
GO_REF:0000024
(MGI:2446974|PMID:12359733)		 Ensembl
RGD
UniProt		 PMID:12359733 GO_REF:0000024 GO_REF:0000107 MGI:2446974 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000 		JBrowse link
G Pla2g15 phospholipase A2, group XV involved_in ISO
ISS		 (PMID:29724779)
GO_REF:0000024		 RGD
UniProt		 PMID:29724779 GO_REF:0000024 NCBI chr19:34,050,685...34,068,070
Ensembl chr19:34,050,694...34,068,063 		JBrowse link
G Pla2g1b phospholipase A2 group IB involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:1420353)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:1420353 GO_REF:0000024 GO_REF:0000107 NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226 		JBrowse link
G Pla2g2d phospholipase A2, group IID involved_in ISO (MGI:1346886|PMID:10531313) RGD PMID:10531313 MGI:1346886 NCBI chr 5:151,016,010...151,022,531
Ensembl chr 5:151,018,870...151,022,525 		JBrowse link
G Pla2g2e phospholipase A2, group IIE involved_in ISO (MGI:1346886|PMID:10531313) RGD PMID:10531313 MGI:1346886 NCBI chr 5:151,121,392...151,127,157
Ensembl chr 5:151,121,439...151,126,821 		JBrowse link
G Pla2g3 phospholipase A2, group III involved_in ISO (PMID:28947740) RGD PMID:28947740 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913 		JBrowse link
cardiolipin acyl-chain remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:23152787)		 UniProt
RGD		 PMID:23152787 GO_REF:0000024 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869 		JBrowse link
G Pla2g5 phospholipase A2, group V involved_in ISO
IEA
ISS		 (PMID:23533611)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:23533611 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658 		JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in ISO
IEA
IBA
IDA
ISS		 (PMID:23533611)
GO_REF:0000107
PMID:21873635
PMID:24648512
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:23533611 PMID:21873635 PMID:24648512 GO_REF:0000024 GO_REF:0000107, RGD:13792537, RGD:25671395 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114 		JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:152,065,539...152,076,178
Ensembl chr  X:152,065,609...152,074,001 		JBrowse link
G Them5 thioesterase superfamily member 5 involved_in IBA
ISO		 PMID:21873635
(MGI:5432849|PMID:22586271)		 RGD PMID:22586271 PMID:21873635 MGI:5432849, RGD:13792537 NCBI chr 2:181,980,783...181,986,002
Ensembl chr 2:181,980,783...181,986,002 		JBrowse link
cardiolipin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crls1 cardiolipin synthase 1 involved_in ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(PMID:16678169)		 UniProt
RGD		 PMID:16678169 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 3:120,119,822...120,138,674
Ensembl chr 3:120,119,852...120,138,655 		JBrowse link
G Pgs1 phosphatidylglycerophosphate synthase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:103,214,635...103,250,254
Ensembl chr10:103,214,646...103,250,254 		JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in ISO
IEA		 (PMID:19164547)
GO_REF:0000107		 RGD
Ensembl		 PMID:19164547 GO_REF:0000107 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114 		JBrowse link
G Plscr3 phospholipid scramblase 3 involved_in ISO
IEA
ISS		 (PMID:16939411)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:16939411 GO_REF:0000024 GO_REF:0000107 NCBI chr10:54,566,556...54,573,240
Ensembl chr10:54,566,873...54,578,709 		JBrowse link
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5288296|PMID:21641550)		 UniProt
RGD		 PMID:21641550 GO_REF:0000024 MGI:5288296 NCBI chr 3:76,889,922...76,899,427
Ensembl chr 3:76,889,922...76,899,427 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
(PMID:19523918)		 Ensembl
RGD		 PMID:19523918 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063 		JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase involved_in ISO (PMID:11118295), (PMID:16873891), (PMID:17043667), (PMID:19164547) RGD PMID:11118295 PMID:16873891 PMID:17043667 PMID:19164547 NCBI chr  X:152,065,539...152,076,178
Ensembl chr  X:152,065,609...152,074,001 		JBrowse link
G Tamm41 TAM41 mitochondrial translocator assembly and maintenance homolog involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:148,070,388...148,103,728
Ensembl chr 4:148,018,463...148,103,694 		JBrowse link
cardiolipin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mecp2 methyl CpG binding protein 2 acts_upstream_of_or_within ISO MGI:2137311 (MGI:3769075|PMID:17237885) RGD PMID:17237885 MGI:3769075 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
G Pnpla8 patatin-like phospholipase domain containing 8 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5917216|PMID:28442572)
(PMID:28442572)		 UniProt
RGD		 PMID:28442572 GO_REF:0000024 MGI:5917216 NCBI chr 6:61,329,810...61,391,736
Ensembl chr 6:61,329,810...61,391,734 		JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase involved_in ISO (PMID:26908608), (PMID:33096711)
(PMID:19700766)
(MGI:4868510|PMID:21068380), (MGI:5819036|PMID:26114544)		 RGD PMID:19700766 PMID:21068380 PMID:26114544 PMID:26908608 PMID:33096711 MGI:4868510 MGI:5819036 NCBI chr  X:152,065,539...152,076,178
Ensembl chr  X:152,065,609...152,074,001 		JBrowse link
phosphatidylglycerol acyl-chain remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g2f phospholipase A2, group IIF involved_in ISO (PMID:11112443) RGD PMID:11112443 NCBI chr 5:150,986,788...150,993,175
Ensembl chr 5:150,986,788...150,993,175 		JBrowse link
G Serac1 serine active site containing 1 involved_in ISO (PMID:22683713) RGD PMID:22683713 NCBI chr 1:46,620,741...46,656,801
Ensembl chr 1:46,620,498...46,656,727 		JBrowse link
phosphatidylglycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial involved_in ISO
ISS
IEA		 (PMID:19075029)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:19075029 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 involved_in ISO (PMID:19523918) RGD PMID:19523918 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063 		JBrowse link
phosphatidylglycerol catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g4a phospholipase A2 group IVA involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:9425121)		 UniProt
Ensembl
RGD		 PMID:9425121 GO_REF:0000024 GO_REF:0000107 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Plb1 phospholipase B1 involved_in IDA PMID:9442064 UniProt PMID:9442064 RGD:30309923 NCBI chr 6:24,087,051...24,227,167
Ensembl chr 6:24,089,214...24,210,117 		JBrowse link
positive regulation of cardiolipin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase IMP RGD PMID:20348225 RGD:13432160 NCBI chr  X:152,065,539...152,076,178
Ensembl chr  X:152,065,609...152,074,001 		JBrowse link
regulation of cardiolipin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 involved_in ISO (MGI:5604945|PMID:24856930) RGD PMID:24856930 MGI:5604945 NCBI chr 2:116,923,272...116,945,312
Ensembl chr 2:116,923,272...116,945,264 		JBrowse link
G Phb2 prohibitin 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5604945|PMID:24856930)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:24856930 GO_REF:0000024 GO_REF:0000107 MGI:5604945 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19818
    metabolic process 12096
      cellular metabolic process 7496
        cellular lipid metabolic process 1052
          glycerolipid metabolic process 388
            glycerophospholipid metabolic process 283
              phosphatidylglycerol metabolic process 27
                cardiolipin metabolic process + 15
                phosphatidylglycerol acyl-chain remodeling 2
                phosphatidylglycerol biosynthetic process + 9
                phosphatidylglycerol catabolic process 2
Path 2
Term Annotations click to browse term
  biological_process 19818
    metabolic process 12096
      cellular metabolic process 7496
        phosphorus metabolic process 2846
          phosphate-containing compound metabolic process 2817
            phospholipid metabolic process 377
              glycerophospholipid metabolic process 283
                phosphatidylglycerol metabolic process 27
                  cardiolipin metabolic process + 15
                  phosphatidylglycerol acyl-chain remodeling 2
                  phosphatidylglycerol biosynthetic process + 9
                  phosphatidylglycerol catabolic process 2
paths to the root