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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet activating factor metabolic process
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Accession:GO:0046469 term browser browse the term
Definition:The chemical reactions and pathways involving platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.
Synonyms:exact_synonym: PAF metabolic process;   PAF metabolism;   platelet activating factor metabolism


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platelet activating factor metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g6 phospholipase A2 group VI involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 7:120,519,479...120,559,716
Ensembl chr 7:120,519,467...120,559,347
JBrowse link
G Pla2g7 phospholipase A2 group VII involved_in ISO (PMID:10066756), (PMID:10504265), (PMID:11590221), (PMID:8624782) RGD PMID:8624782 PMID:10066756 PMID:10504265 PMID:11590221 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
platelet activating factor biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chpt1 choline phosphotransferase 1 involved_in ISO (PMID:10893425) RGD PMID:10893425 NCBI chr 7:29,019,518...29,070,928
Ensembl chr 7:29,043,916...29,070,928
JBrowse link
G Lpcat2 lysophosphatidylcholine acyltransferase 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3708195|PMID:17182612)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:17182612 GO_REF:0000024 GO_REF:0000107 MGI:3708195 NCBI chr19:15,470,177...15,540,704
Ensembl chr19:15,469,303...15,540,773
JBrowse link
G Pla2g4a phospholipase A2 group IVA involved_in IEA
ISO
GO_REF:0000107
(MGI:1100762|PMID:9403692)
Ensembl
RGD
PMID:9403692 GO_REF:0000107 MGI:1100762 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Pla2g4c phospholipase A2 group IVC involved_in ISO (PMID:19501189) RGD PMID:19501189 NCBI chr 1:75,440,035...75,481,995
Ensembl chr 1:75,428,027...75,620,911
JBrowse link
G Pla2g5 phospholipase A2, group V IDA RGD PMID:11106649 RGD:2303037 NCBI chr 5:157,247,601...157,268,968
Ensembl chr 5:157,247,781...157,268,903
JBrowse link
platelet activating factor catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g10 phospholipase A2, group X involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:16962371)
Ensembl
UniProt
RGD
PMID:16962371 GO_REF:0000024 GO_REF:0000107 NCBI chr10:1,509,732...1,520,970
Ensembl chr10:1,509,732...1,520,970
JBrowse link
G Pla2g7 phospholipase A2 group VII involved_in ISO (PMID:16371369) RGD PMID:16371369 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    metabolic process 11797
      nitrogen compound metabolic process 10017
        organonitrogen compound metabolic process 6803
          platelet activating factor metabolic process 8
            platelet activating factor biosynthetic process 5
            platelet activating factor catabolic process 2
Path 2
Term Annotations click to browse term
  biological_process 19491
    metabolic process 11797
      cellular metabolic process 10755
        phosphorus metabolic process 2829
          phosphate-containing compound metabolic process 2807
            phospholipid metabolic process 377
              glycerophospholipid metabolic process 288
                platelet activating factor metabolic process 8
                  platelet activating factor biosynthetic process 5
                  platelet activating factor catabolic process 2
paths to the root