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ONTOLOGY REPORT - ANNOTATIONS

Term:membrane lipid catabolic process
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Accession:GO:0046466 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane.
Synonyms:exact_synonym: membrane lipid breakdown;   membrane lipid catabolism;   membrane lipid degradation
 broad_synonym: membrane lipid peroxidation


show annotations for term's descendants           Sort by:
membrane lipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:19005183), (PMID:23979599)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19005183 PMID:23979599 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 involved_in ISO (PMID:23409838) RGD PMID:23409838 NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828 		JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B involved_in ISO (PMID:26095358) RGD PMID:26095358 NCBI chr 5:144,944,618...144,966,703
Ensembl chr 5:144,944,636...144,966,720 		JBrowse link
G Zpbp2 zona pellucida binding protein 2 acts_upstream_of_or_within ISO MGI:3762590 (PMID:29536159) RGD PMID:29536159 NCBI chr10:83,558,772...83,567,511
Ensembl chr10:83,559,016...83,567,508 		JBrowse link
ceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer1 alkaline ceramidase 1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:20207939)
(PMID:27126290)
(PMID:12783875)
GO_REF:0000033		 RGD
GO_Central		 PMID:12783875 PMID:20207939 PMID:27126290 GO_REF:0000033 NCBI chr 9:1,794,340...1,824,432
Ensembl chr 9:1,793,139...1,824,434 		JBrowse link
G Acer2 alkaline ceramidase 2 involved_in ISO
IBA		 (PMID:16940153), (PMID:20207939)
GO_REF:0000033		 RGD
GO_Central		 PMID:16940153 PMID:20207939 GO_REF:0000033 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Acer3 alkaline ceramidase 3 involved_in ISO (PMID:20207939), (PMID:26792856), (PMID:30575723)
(PMID:26474409)		 RGD PMID:20207939 PMID:26474409 PMID:26792856 PMID:30575723 NCBI chr 1:152,504,180...152,606,596
Ensembl chr 1:152,504,186...152,606,591 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:23770692), (PMID:9653654)
GO_REF:0000107
(PMID:10610716), (PMID:12815059)		 UniProt
RGD
Ensembl		 PMID:9653654 PMID:10610716 PMID:12815059 PMID:23770692 GO_REF:0000024 GO_REF:0000107 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in IDA
ISO
IBA
IEA		 PMID:10488143
(PMID:10652340), (PMID:16126722), (PMID:16380386)
GO_REF:0000033
GO_REF:0000002
PMID:15123644
PMID:15217782
(PMID:10781606), (PMID:15946935), (PMID:16229686), (PMID:17475390), (PMID:19345744), (PMID:30154232)		 RGD
GO_Central
InterPro		 PMID:10652340 PMID:10781606 PMID:15946935 PMID:16126722 PMID:16229686 More... GO_REF:0000002 GO_REF:0000033, RGD:13838800, RGD:13838793, RGD:13838794 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162 		JBrowse link
G Cel carboxyl ester lipase involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
MGI:2180867 (PMID:11733511)		 Ensembl
GO_Central
RGD		 PMID:11733511 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035 		JBrowse link
ceramide phosphoethanolamine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Etnppl ethanolamine-phosphate phospho-lyase acts_upstream_of_or_within ISO (PMID:34048714) RGD PMID:34048714 NCBI chr 2:219,173,048...219,194,646
Ensembl chr 2:219,172,978...219,192,212 		JBrowse link
galactolipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnliprp2 pancreatic lipase related protein 2 involved_in IDA
ISO		 (PMID:15287741), (PMID:17401110), (PMID:18702514), (PMID:20083229) RGD PMID:15287741 PMID:17401110 PMID:18702514 PMID:20083229 PMID:8765145 RGD:2303162 NCBI chr 1:257,897,766...257,916,434
Ensembl chr 1:257,897,766...257,916,434 		JBrowse link
galactosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Galc galactosylceramidase involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:8399327)
(PMID:8769874)
MGI:1856218 (PMID:11371512)
GO_REF:0000033		 RGD
GO_Central		 PMID:8399327 PMID:8769874 PMID:11371512 GO_REF:0000033 NCBI chr 6:117,452,888...117,522,281
Ensembl chr 6:117,452,895...117,515,830 		JBrowse link
G Gba3 glucosylceramidase beta 3 involved_in ISO (PMID:17595169) RGD PMID:17595169 NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO MGI:2183897 (PMID:11371512) RGD PMID:11371512 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498 		JBrowse link
ganglioside catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glb1 galactosidase, beta 1 involved_in ISO
IEA		 (PMID:31720227)
GO_REF:0000107		 RGD
Ensembl		 PMID:31720227 GO_REF:0000107 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127 		JBrowse link
G Gm2a ganglioside GM2 activator involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1861930 (PMID:9223328)		 GO_Central
RGD		 PMID:9223328 GO_REF:0000033 NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757 		JBrowse link
G Hexa hexosaminidase subunit alpha involved_in
acts_upstream_of_or_within		 ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
MGI:1857181|MGI:2429698 (PMID:7937929), (PMID:8789434), (PMID:9223328), (PMID:9645704)
(PMID:8123671), (PMID:8672428), (PMID:9694901)		 UniProt
GO_Central
RGD		 PMID:7937929 PMID:8123671 PMID:8672428 PMID:8789434 PMID:9223328 More... GO_REF:0000024 GO_REF:0000033 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013 		JBrowse link
G Hexb hexosaminidase subunit beta involved_in
acts_upstream_of_or_within		 ISS
IBA
ISO
IEA		 GO_REF:0000024
GO_REF:0000033
MGI:1857438|MGI:2429701 (PMID:10021458), (PMID:12657883), (PMID:12756243), (PMID:15748167), (PMID:8566348), (PMID:8789434), (PMID:9223328), (PMID:9645704)
(PMID:8123671), (PMID:8672428)
GO_REF:0000107		 UniProt
GO_Central
RGD
Ensembl		 PMID:8123671 PMID:8566348 PMID:8672428 PMID:8789434 PMID:9223328 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223 		JBrowse link
G Neu1 neuraminidase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,897,480...3,901,745
Ensembl chr20:3,897,480...3,901,745 		JBrowse link
G Neu2 neuraminidase 2 involved_in ISS
ISO
IBA
IEA		 GO_REF:0000024
(PMID:10713120)
GO_REF:0000033
GO_REF:0000107
(PMID:14613940), (PMID:22228546)		 UniProt
RGD
GO_Central
Ensembl		 PMID:10713120 PMID:14613940 PMID:22228546 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:88,218,494...88,267,356
Ensembl chr 9:88,249,135...88,267,355 		JBrowse link
G Neu3 neuraminidase 3 involved_in ISO
IBA
ISS		 (PMID:10861246), (PMID:11298736), (PMID:15847605), (PMID:17334392)
(PMID:11696012), (PMID:14970224), (PMID:17708748)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:10861246 PMID:11298736 PMID:11696012 PMID:14970224 PMID:15847605 More... GO_REF:0000024 GO_REF:0000033 NCBI chr 1:154,137,732...154,148,879
Ensembl chr 1:154,050,855...154,148,813 		JBrowse link
G Neu4 neuraminidase 4 involved_in ISO
IBA		 (PMID:15213228), (PMID:15847605)
(PMID:19506080)
GO_REF:0000033		 RGD
GO_Central		 PMID:15213228 PMID:15847605 PMID:19506080 GO_REF:0000033 NCBI chr 9:94,396,920...94,402,576
Ensembl chr 9:94,396,920...94,402,576 		JBrowse link
glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba1 glucosylceramidase beta 1 involved_in ISO
IBA		 (PMID:16293621), (PMID:19279011), (PMID:21700325), (PMID:24022302), (PMID:24211208), (PMID:25584808), (PMID:9201993)
(PMID:21700325), (PMID:23707074), (PMID:24211208)
GO_REF:0000033		 RGD
GO_Central		 PMID:9201993 PMID:16293621 PMID:19279011 PMID:21700325 PMID:23707074 More... GO_REF:0000033 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Gba2 glucosylceramidase beta 2 involved_in ISO
IEA
ISS		 (PMID:17080196), (PMID:30308956)
(PMID:17080196), (PMID:23250757)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17080196 PMID:23250757 PMID:30308956 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:57,822,389...57,834,522
Ensembl chr 5:57,822,389...57,834,072 		JBrowse link
G Gba3 glucosylceramidase beta 3 involved_in
NOT|involved_in		 ISO (PMID:17595169), (PMID:26724485)
(PMID:20728381)		 RGD PMID:17595169 PMID:20728381 PMID:26724485 NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653 		JBrowse link
glycolipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Naga alpha-N-acetylgalactosaminidase involved_in ISO
IEA
ISS		 (PMID:9741689)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:9741689 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:113,846,358...113,855,430
Ensembl chr 7:113,846,374...113,855,315 		JBrowse link
glycosphingolipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gla galactosidase, alpha involved_in ISO
IMP		 (PMID:10838196), (PMID:8804427) RGD PMID:8804427 PMID:10838196 PMID:34320241 RGD:401976418 NCBI chr  X:97,769,227...97,780,646
Ensembl chr  X:97,768,996...97,780,664 		JBrowse link
glycosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba3 glucosylceramidase beta 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653 		JBrowse link
G Gla galactosidase, alpha acts_upstream_of_or_within ISO MGI:1861794 (PMID:10840053), (PMID:10841515), (PMID:11752062), (PMID:15629890), (PMID:9122231) RGD PMID:9122231 PMID:10840053 PMID:10841515 PMID:11752062 PMID:15629890 NCBI chr  X:97,769,227...97,780,646
Ensembl chr  X:97,768,996...97,780,664 		JBrowse link
G Lct lactase involved_in IDA PMID:4752949 UniProt PMID:4752949 RGD:151356630 NCBI chr13:39,781,929...39,824,456
Ensembl chr13:39,781,929...39,824,456 		JBrowse link
positive regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcd protein kinase C, delta involved_in ISO
IEA		 (PMID:19279011)
GO_REF:0000107		 RGD
Ensembl		 PMID:19279011 GO_REF:0000107 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
positive regulation of sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21177474)		 UniProt
RGD		 PMID:21177474 GO_REF:0000024 NCBI chr10:104,242,169...104,247,185
Ensembl chr10:104,242,223...104,246,589 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
IEA		 (PMID:19279011)
GO_REF:0000107		 RGD
Ensembl		 PMID:19279011 GO_REF:0000107 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
regulation of glucosylceramide catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir127 microRNA 127 acts_upstream_of ISO UniProtKB:P04062 (PMID:25584808) RGD PMID:25584808 NCBI chr 6:128,546,215...128,546,311
Ensembl chr 6:128,546,215...128,546,311 		JBrowse link
G Mir16 microRNA 16 acts_upstream_of_or_within ISO UniProtKB:P04062 (PMID:25584808) RGD PMID:25584808 NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443 		JBrowse link
G Mir195 microRNA 195 acts_upstream_of_or_within ISO UniProtKB:P04062 (PMID:25584808) RGD PMID:25584808 NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924 		JBrowse link
sphingolipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:14500380)		 UniProt
Ensembl
RGD		 PMID:14500380 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:24809814), (PMID:28165339)		 UniProt
GO_Central
Ensembl
RGD		 PMID:24809814 PMID:28165339 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:29,047,793...29,094,209
Ensembl chr20:29,047,796...29,094,084 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:44,986,229...44,989,343
Ensembl chr20:44,986,231...44,989,441 		JBrowse link
G Vps54 VPS54 subunit of GARP complex involved_in IEA
ISO		 GO_REF:0000107
MGI:1857091 (PMID:32345721)		 Ensembl
RGD		 PMID:32345721 GO_REF:0000107 NCBI chr14:95,378,821...95,455,871
Ensembl chr14:95,378,012...95,455,857 		JBrowse link
sphingomyelin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smpd1 sphingomyelin phosphodiesterase 1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:18815062), (PMID:20807762), (PMID:22573858)
(PMID:23973266)
GO_REF:0000033		 RGD
GO_Central		 PMID:18815062 PMID:20807762 PMID:22573858 PMID:23973266 GO_REF:0000033 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:10608884), (PMID:14741383)
(PMID:9520418)
(PMID:23973266)
GO_REF:0000107		 RGD
Ensembl		 PMID:9520418 PMID:10608884 PMID:14741383 PMID:23973266 GO_REF:0000107 NCBI chr20:44,986,229...44,989,343
Ensembl chr20:44,986,231...44,989,441 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:23973266)
(PMID:14741383)		 Ensembl
RGD		 PMID:14741383 PMID:23973266 GO_REF:0000107 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 involved_in ISO
IBA		 (PMID:16517606), (PMID:25180167)
(PMID:25180167)
GO_REF:0000033		 RGD
GO_Central		 PMID:16517606 PMID:25180167 GO_REF:0000033 NCBI chr11:83,362,534...83,386,257
Ensembl chr11:83,362,534...83,386,250 		JBrowse link
G Smpd5 sphingomyelin phosphodiesterase 5 involved_in ISO (PMID:21183079) RGD PMID:21183079 NCBI chr 7:108,009,182...108,011,767
Ensembl chr 7:108,009,173...108,011,763 		JBrowse link
G Smpdl3a sphingomyelin phosphodiesterase, acid-like 3A NOT|involved_in ISO
ISS		 (PMID:26783088)
GO_REF:0000024		 RGD
UniProt		 PMID:26783088 GO_REF:0000024 NCBI chr20:37,132,592...37,155,567
Ensembl chr20:37,132,592...37,155,567 		JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:144,944,618...144,966,703
Ensembl chr 5:144,944,636...144,966,720 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        catabolic process 2871
          lipid catabolic process 356
            membrane lipid catabolic process 42
              glycolipid catabolic process + 21
              sphingolipid catabolic process + 37
Path 2
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      metabolic process 11953
        primary metabolic process 10582
          lipid metabolic process 1452
            membrane lipid metabolic process 207
              membrane lipid catabolic process 42
                glycolipid catabolic process + 21
                sphingolipid catabolic process + 37
paths to the root