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ONTOLOGY REPORT - ANNOTATIONS


Term:acylglycerol biosynthetic process
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Accession:GO:0046463 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
Synonyms:exact_synonym: acylglycerol anabolism;   acylglycerol biosynthesis;   acylglycerol formation;   acylglycerol synthesis



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diacylglycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANG angiogenin involved_in IDA (PMID:2457905) UniProt
UniProt
PMID:2457905 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971
JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535
JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr10:112,149,865...112,216,306
Ensembl chr10:112,149,865...112,215,377
JBrowse link
G MOGAT1 monoacylglycerol O-acyltransferase 1 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:2181469|PMID:12077311)
GO_Central
GO_Central
Ensembl
MGI
PMID:12077311 PMID:21873635 GO_REF:0000107 MGI:2181469 NCBI chr 2:222,671,658...222,709,930
Ensembl chr 2:222,671,658...222,709,930
JBrowse link
G MOGAT2 monoacylglycerol O-acyltransferase 2 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
(PMID:21873635)
(MGI:2656067|PMID:12576479), (MGI:3040558|PMID:14966132)
GO_Central
Ensembl
GO_Central
MGI
PMID:12576479 PMID:14966132 PMID:21873635 GO_REF:0000107 MGI:2656067 MGI:3040558 NCBI chr11:75,717,819...75,732,953
Ensembl chr11:75,717,838...75,732,958
JBrowse link
G PLA2G15 phospholipase A2 group XV involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr16:68,245,371...68,261,062
Ensembl chr16:68,245,304...68,261,058
JBrowse link
G PLCE1 phospholipase C epsilon 1 involved_in TAS
IMP
(PMID:11022047)
(PMID:29058690)
UniProt
UniProt
PMID:11022047 PMID:29058690 NCBI chr10:93,993,931...94,332,823
Ensembl chr10:93,993,931...94,332,823
JBrowse link
G PNPLA2 patatin like phospholipase domain containing 2 involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr11:818,914...825,573
Ensembl chr11:818,914...825,573
JBrowse link
glycerol biosynthetic process from pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PCK1 phosphoenolpyruvate carboxykinase 1 involved_in
acts_upstream_of_or_within
IBA
IEA
ISS
ISO
(PMID:21873635)
(MGI:2157262|PMID:11792850)
GO_Central
Ensembl
BHF-UCL
GO_Central
MGI
BHF-UCL
PMID:11792850 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:2157262 NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121
JBrowse link
G PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr14:24,094,311...24,104,125
Ensembl chr14:24,094,053...24,110,598
JBrowse link
monoacylglycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AWAT2 acyl-CoA wax alcohol acyltransferase 2 involved_in IDA (PMID:28420705) UniProt
UniProt
PMID:28420705 NCBI chr  X:70,040,542...70,049,970
Ensembl chr  X:70,040,542...70,049,938
JBrowse link
G DGAT1 diacylglycerol O-acyltransferase 1 involved_in IDA
IEA
(PMID:28420705) UniProt
Ensembl
UniProt
PMID:28420705 GO_REF:0000107 NCBI chr 8:144,314,584...144,326,852
Ensembl chr 8:144,314,584...144,326,910
JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 involved_in IDA (PMID:28420705) UniProt
UniProt
PMID:28420705 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535
JBrowse link
G DGAT2L6 diacylglycerol O-acyltransferase 2 like 6 involved_in IDA (PMID:28420705) UniProt
UniProt
PMID:28420705 NCBI chr  X:70,177,483...70,205,704
Ensembl chr  X:70,177,483...70,205,704
JBrowse link
G MOGAT2 monoacylglycerol O-acyltransferase 2 involved_in IDA (PMID:28420705) UniProt
UniProt
PMID:28420705 NCBI chr11:75,717,819...75,732,953
Ensembl chr11:75,717,838...75,732,958
JBrowse link
G MOGAT3 monoacylglycerol O-acyltransferase 3 involved_in IDA (PMID:28420705) UniProt
UniProt
PMID:28420705 NCBI chr 7:101,192,886...101,201,131
Ensembl chr 7:101,195,007...101,201,038
JBrowse link
G PLA2G4A phospholipase A2 group IVA involved_in IDA (PMID:7794891) UniProt
UniProt
PMID:7794891 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981
JBrowse link
negative regulation of phosphatidate phosphatase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LPIN1 lipin 1 involved_in ISO
IEA
RGD
Ensembl
Ensembl
PMID:21715287 GO_REF:0000107 RGD:38599010 NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409
JBrowse link
negative regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FBXW7 F-box and WD repeat domain containing 7 involved_in ISS BHF-UCL
BHF-UCL
GO_REF:0000024 NCBI chr 4:152,320,544...152,536,873
Ensembl chr 4:152,320,544...152,536,092
JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO RGD PMID:29148806 RGD:15042869 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
JBrowse link
G SIK1 salt inducible kinase 1 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr21:43,414,483...43,427,131
Ensembl chr21:43,414,483...43,427,131
JBrowse link
G SIK1B salt inducible kinase 1B (putative) involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr21:6,111,131...6,123,778
Ensembl chr21:6,111,131...6,123,778
JBrowse link
positive regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL5 acyl-CoA synthetase long chain family member 5 ISO RGD PMID:16263710 RGD:2312807 NCBI chr10:112,374,116...112,428,376
Ensembl chr10:112,374,116...112,428,379
JBrowse link
G APOC3 apolipoprotein C3 ISO RGD PMID:23542898 RGD:10054091 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072
JBrowse link
G CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 involved_in IGI (PMID:22134922) UniProt
UniProt
PMID:22134922 NCBI chr16:50,025,225...50,037,081
Ensembl chr16:50,024,410...50,037,088
JBrowse link
G CTDNEP1 CTD nuclear envelope phosphatase 1 involved_in IGI (PMID:22134922) UniProt
UniProt
PMID:22134922 NCBI chr17:7,243,591...7,251,978
Ensembl chr17:7,243,591...7,252,491
JBrowse link
G DGAT1 diacylglycerol O-acyltransferase 1 ISO RGD PMID:23449193 RGD:10400846 NCBI chr 8:144,314,584...144,326,852
Ensembl chr 8:144,314,584...144,326,910
JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:17526931 GO_REF:0000107 RGD:10400884 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535
JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial ISO RGD PMID:15598672 RGD:2313665 NCBI chr10:112,149,865...112,216,306
Ensembl chr10:112,149,865...112,215,377
JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr 6:24,423,969...24,495,232
Ensembl chr 6:24,424,565...24,495,205
JBrowse link
G LDLR low density lipoprotein receptor involved_in ISS
IEA
BHF-UCL
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr19:11,089,432...11,133,820
Ensembl chr19:11,089,462...11,133,820
JBrowse link
G MFSD2A major facilitator superfamily domain containing 2A acts_upstream_of_or_within
involved_in
ISS
IEA
ARUK-UCL
ARUK-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:39,955,145...39,969,956
Ensembl chr 1:39,955,112...39,969,968
JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 involved_in IMP (PMID:17186944) BHF-UCL
BHF-UCL
PMID:17186944 NCBI chr19:50,376,457...50,383,388
Ensembl chr19:50,329,653...50,383,388
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in IMP (PMID:17693624) BHF-UCL
BHF-UCL
PMID:17693624 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033
JBrowse link
G PLIN5 perilipin 5 involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr19:4,522,531...4,535,224
Ensembl chr19:4,522,531...4,535,224
JBrowse link
G RGN regucalcin involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:16817230 GO_REF:0000107 RGD:9590221 NCBI chr  X:47,078,414...47,093,313
Ensembl chr  X:47,078,355...47,093,314
JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in ISS
IEA
BHF-UCL
BHF-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
JBrowse link
G SLC27A1 solute carrier family 27 member 1 involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr19:17,468,745...17,506,169
Ensembl chr19:17,468,769...17,506,168
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within
ISS
IEA
ISO
(MGI:3603730|PMID:16046411) UniProt
Ensembl
UniProt
MGI
PMID:16046411 GO_REF:0000024 GO_REF:0000107 MGI:3603730 NCBI chr17:17,811,334...17,837,017
Ensembl chr17:17,810,399...17,837,002
JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (MGI:5468191|PMID:23260145) MGI PMID:23260145 MGI:5468191 NCBI chr10:112,950,247...113,167,678
Ensembl chr10:112,950,247...113,167,678
JBrowse link
regulation of diacylglycerol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AVIL advillin involved_in IMP (PMID:29058690) UniProt
UniProt
PMID:29058690 NCBI chr12:57,797,376...57,818,734
Ensembl chr12:57,797,376...57,818,734
JBrowse link
regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IDA (PMID:10432298) UniProt
UniProt
PMID:10432298 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G FITM2 fat storage inducing transmembrane protein 2 involved_in ISS
IEA
(PMID:18160536) BHF-UCL
BHF-UCL
Ensembl
PMID:18160536 GO_REF:0000107 NCBI chr20:44,302,840...44,311,202
Ensembl chr20:44,302,840...44,311,202
JBrowse link
G THRSP thyroid hormone responsive involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr11:78,063,861...78,068,351
Ensembl chr11:78,063,861...78,068,351
JBrowse link
triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL1 acyl-CoA synthetase long chain family member 1 involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:16466685 GO_REF:0000107 RGD:2312800 NCBI chr 4:184,755,595...184,826,593
Ensembl chr 4:184,755,595...184,826,818
JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 ISO RGD PMID:16466685 RGD:2312800 NCBI chr  X:109,641,335...109,733,325
Ensembl chr  X:109,624,244...109,733,403
JBrowse link
G ACSL6 acyl-CoA synthetase long chain family member 6 ISO RGD PMID:16466685 RGD:2312800 NCBI chr 5:131,949,973...132,012,068
Ensembl chr 5:131,949,973...132,012,243
JBrowse link
G AGMO alkylglycerol monooxygenase involved_in TAS Reactome
Reactome
Reactome:R-HSA-75109 NCBI chr 7:15,117,223...15,562,015
Ensembl chr 7:15,200,317...15,562,015
JBrowse link
G DGAT1 diacylglycerol O-acyltransferase 1 involved_in
acts_upstream_of_or_within
IBA
IDA
IEA
ISO
(PMID:21873635)
(PMID:18458083)
(PMID:18238778), (PMID:32433610), (PMID:32433611)
GO_Central
MGI
GO_Central
Ensembl
InterPro
UniProt
MGI
UniProt
RGD
PMID:14596837 PMID:18238778 PMID:18458083 PMID:21873635 PMID:32433610 More... GO_REF:0000002 GO_REF:0000107 RGD:1625586 NCBI chr 8:144,314,584...144,326,852
Ensembl chr 8:144,314,584...144,326,910
JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 involved_in
acts_upstream_of_or_within
IDA
IEA
TAS
IBA
ISO
(PMID:11481335), (PMID:27184406)
(PMID:21873635)
(MGI:2151970|PMID:11481335), (MGI:2181469|PMID:12077311)
(MGI:3036977|PMID:14668353)
UniProt
Ensembl
Reactome
GO_Central
UniProt
MGI
Reactome
GO_Central
PMID:11481335 PMID:12077311 PMID:14668353 PMID:21873635 PMID:27184406 GO_REF:0000041 GO_REF:0000107 MGI:2151970 MGI:2181469 MGI:3036977 Reactome:R-HSA-75109 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535
JBrowse link
G GK glycerol kinase involved_in TAS Reactome
Reactome
Reactome:R-HSA-75109 NCBI chr  X:30,653,348...30,731,462
Ensembl chr  X:30,653,359...30,731,462
JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial involved_in TAS
IBA
IDA
(PMID:21873635)
(PMID:18238778)
Reactome
Reactome
GO_Central
UniProt
UniProt
GO_Central
PMID:18238778 PMID:21873635 Reactome:R-HSA-75109 NCBI chr10:112,149,865...112,216,306
Ensembl chr10:112,149,865...112,215,377
JBrowse link
G GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial involved_in
acts_upstream_of_or_within
IBA
ISS
IEA
ISO
(PMID:21873635)
(MGI:3762297|PMID:17689486)
GO_Central
UniProt
GO_Central
Ensembl
MGI
UniProt
PMID:17689486 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:3762297 NCBI chr 2:96,021,946...96,036,265
Ensembl chr 2:96,021,946...96,039,451
JBrowse link
G GPAT3 glycerol-3-phosphate acyltransferase 3 involved_in IEA
IDA
(PMID:17170135) UniProt
UniProt
Ensembl
PMID:17170135 GO_REF:0000041 GO_REF:0000107 NCBI chr 4:83,535,634...83,605,875
Ensembl chr 4:83,535,914...83,605,875
JBrowse link
G GPAT4 glycerol-3-phosphate acyltransferase 4 NOT|involved_in IDA
ISS
(PMID:18238778) UniProt
UniProt
PMID:18238778 GO_REF:0000024 NCBI chr 8:41,578,190...41,625,001
Ensembl chr 8:41,577,187...41,625,001
JBrowse link
G LPGAT1 lysophosphatidylglycerol acyltransferase 1 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr 1:211,743,457...211,830,763
Ensembl chr 1:211,743,457...211,830,763
JBrowse link
G LPIN1 lipin 1 involved_in IBA
IEA
TAS
(PMID:21873635) GO_Central
InterPro
Reactome
GO_Central
Reactome
InterPro
PMID:21873635 GO_REF:0000002 Reactome:R-HSA-75109 NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409
JBrowse link
G LPIN2 lipin 2 involved_in TAS
IBA
(PMID:21873635) Reactome
Reactome
GO_Central
GO_Central
PMID:21873635 Reactome:R-HSA-75109 NCBI chr18:2,916,994...3,013,201
Ensembl chr18:2,916,994...3,013,144
JBrowse link
G LPIN3 lipin 3 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr20:41,340,779...41,360,583
Ensembl chr20:41,340,821...41,360,582
JBrowse link
G LPL lipoprotein lipase involved_in IEA
ISO
Ensembl
Ensembl
RGD
PMID:11788374 GO_REF:0000107 RGD:70246 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259
JBrowse link
G MOGAT1 monoacylglycerol O-acyltransferase 1 involved_in TAS
IEA
IBA
(PMID:21873635) Reactome
UniProt
GO_Central
Reactome
GO_Central
UniProt
PMID:21873635 GO_REF:0000041 Reactome:R-HSA-75109 NCBI chr 2:222,671,658...222,709,930
Ensembl chr 2:222,671,658...222,709,930
JBrowse link
G MOGAT2 monoacylglycerol O-acyltransferase 2 involved_in
acts_upstream_of_or_within
IEA
TAS
ISO
(MGI:2656067|PMID:12576479) UniProt
UniProt
Reactome
Ensembl
MGI
Reactome
PMID:12576479 GO_REF:0000041 GO_REF:0000107 MGI:2656067 Reactome:R-HSA-75109 NCBI chr11:75,717,819...75,732,953
Ensembl chr11:75,717,838...75,732,958
JBrowse link
G MOGAT3 monoacylglycerol O-acyltransferase 3 involved_in TAS
IEA
IBA
IDA
(PMID:21873635)
(PMID:27184406)
Reactome
UniProt
GO_Central
Reactome
UniProt
GO_Central
PMID:21873635 PMID:27184406 GO_REF:0000041 Reactome:R-HSA-75109 NCBI chr 7:101,192,886...101,201,131
Ensembl chr 7:101,195,007...101,201,038
JBrowse link
G PNPLA3 patatin like phospholipase domain containing 3 involved_in IDA (PMID:15364929), (PMID:22560221) BHF-UCL
BHF-UCL
PMID:15364929 PMID:22560221 NCBI chr22:43,923,805...43,947,582
Ensembl chr22:43,923,792...43,964,488
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18659
    cellular process 17546
      cellular metabolic process 10924
        cellular biosynthetic process 6105
          glycerolipid biosynthetic process 268
            acylglycerol biosynthetic process 52
              diacylglycerol biosynthetic process + 9
              monoacylglycerol biosynthetic process 7
              triglyceride biosynthetic process + 44
Path 2
Term Annotations click to browse term
  biological_process 18659
    metabolic process 12014
      primary metabolic process 10656
        lipid metabolic process 1491
          cellular lipid metabolic process 1081
            glycerolipid metabolic process 423
              acylglycerol metabolic process 147
                acylglycerol biosynthetic process 52
                  diacylglycerol biosynthetic process + 9
                  monoacylglycerol biosynthetic process 7
                  triglyceride biosynthetic process + 44
paths to the root